SG11202002186VA - Novel artificial nucleic acid molecules - Google Patents
Novel artificial nucleic acid moleculesInfo
- Publication number
- SG11202002186VA SG11202002186VA SG11202002186VA SG11202002186VA SG11202002186VA SG 11202002186V A SG11202002186V A SG 11202002186VA SG 11202002186V A SG11202002186V A SG 11202002186VA SG 11202002186V A SG11202002186V A SG 11202002186VA SG 11202002186V A SG11202002186V A SG 11202002186VA
- Authority
- SG
- Singapore
- Prior art keywords
- nucleic acid
- acid molecules
- artificial nucleic
- novel artificial
- novel
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP2017076775 | 2017-10-19 | ||
EP2017076741 | 2017-10-19 | ||
PCT/EP2018/057552 WO2018172556A1 (en) | 2017-03-24 | 2018-03-23 | Nucleic acids encoding crispr-associated proteins and uses thereof |
EP2018076185 | 2018-09-26 | ||
PCT/EP2018/078453 WO2019077001A1 (en) | 2017-10-19 | 2018-10-17 | Novel artificial nucleic acid molecules |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202002186VA true SG11202002186VA (en) | 2020-05-28 |
Family
ID=66173912
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202002186VA SG11202002186VA (en) | 2017-10-19 | 2018-10-17 | Novel artificial nucleic acid molecules |
Country Status (13)
Country | Link |
---|---|
US (1) | US20220233568A1 (en) |
EP (1) | EP3697912A1 (en) |
JP (2) | JP2021501572A (en) |
KR (1) | KR20200071081A (en) |
CN (1) | CN111630173A (en) |
AU (1) | AU2018351481A1 (en) |
BR (1) | BR112020004351A2 (en) |
CA (1) | CA3073634A1 (en) |
IL (1) | IL272850A (en) |
MX (1) | MX2020003995A (en) |
RU (1) | RU2020115287A (en) |
SG (1) | SG11202002186VA (en) |
WO (1) | WO2019077001A1 (en) |
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WO2017109134A1 (en) | 2015-12-22 | 2017-06-29 | Curevac Ag | Method for producing rna molecule compositions |
EP3423595A1 (en) | 2016-03-03 | 2019-01-09 | CureVac AG | Rna analysis by total hydrolysis |
EP3601576A1 (en) | 2017-03-24 | 2020-02-05 | CureVac AG | Nucleic acids encoding crispr-associated proteins and uses thereof |
EP3673069A1 (en) | 2017-08-22 | 2020-07-01 | CureVac AG | Bunyavirales vaccine |
RU2020117848A (en) | 2017-11-08 | 2021-12-08 | Куревак Аг | PHK SEQUENCE ADAPTATION |
EP3723796A1 (en) | 2017-12-13 | 2020-10-21 | CureVac AG | Flavivirus vaccine |
WO2019122371A1 (en) | 2017-12-21 | 2019-06-27 | Curevac Ag | Linear double stranded dna coupled to a single support or a tag and methods for producing said linear double stranded dna |
JP2021519595A (en) * | 2018-04-17 | 2021-08-12 | キュアバック アーゲー | New RSV RNA molecule and vaccination composition |
CN110241116B (en) * | 2019-05-21 | 2023-02-07 | 中国医学科学院放射医学研究所 | Circular RNA and application thereof in promoting DNA damage repair |
US20220313813A1 (en) | 2019-06-18 | 2022-10-06 | Curevac Ag | Rotavirus mrna vaccine |
BR112022001947A2 (en) | 2019-08-14 | 2022-09-20 | Curevac Ag | RNA COMBINATIONS AND COMPOSITIONS WITH REDUCED IMMUNOSTIMULATORY PROPERTIES |
JP2022546417A (en) * | 2019-08-29 | 2022-11-04 | チューリッヒ大学 | Minimal mRNA and its uses |
CN110592223B (en) * | 2019-10-31 | 2022-10-25 | 中南大学湘雅三医院 | Application of diagnostic and prognostic marker hsa _ circRNA _012515 for NSCLC |
CN112759652B (en) * | 2019-11-01 | 2022-09-20 | 北京华夏清医治疗科技有限公司 | Chimeric antigen receptor and application thereof |
US20230008266A1 (en) * | 2019-11-07 | 2023-01-12 | Icahn School Of Medicine At Mount Sinai | Synthetic modified rna and uses thereof |
CN111041025B (en) | 2019-12-17 | 2021-06-18 | 深圳市瑞吉生物科技有限公司 | mRNA targeting molecule based on combination of N-acetylgalactosamine polypeptide and preparation method thereof |
MX2022007680A (en) | 2019-12-20 | 2022-09-26 | Curevac Ag | Lipid nanoparticles for delivery of nucleic acids. |
US11576966B2 (en) | 2020-02-04 | 2023-02-14 | CureVac SE | Coronavirus vaccine |
US11241493B2 (en) | 2020-02-04 | 2022-02-08 | Curevac Ag | Coronavirus vaccine |
IL293571A (en) | 2020-02-04 | 2022-08-01 | Curevac Ag | Coronavirus vaccine |
US20230096704A1 (en) * | 2020-02-05 | 2023-03-30 | University Of Florida Research Foundation, Incorporated | Rna-loaded nanoparticles and use thereof for the treatment of cancer |
AU2021247163A1 (en) * | 2020-04-01 | 2022-10-20 | University Of Florida Research Foundation, Incorporated | Multilamellar RNA nanoparticle vaccine against SARS-CoV-2 |
CN111413498B (en) * | 2020-04-08 | 2023-08-04 | 复旦大学附属中山医院 | Autoantibody 7-AAb detection panel for liver cell liver cancer and application thereof |
KR20230053008A (en) | 2020-05-29 | 2023-04-20 | 큐어백 에스이 | Nucleic Acid-Based Combination Vaccines |
CN111744019B (en) * | 2020-07-01 | 2023-08-04 | 深圳瑞吉生物科技有限公司 | Mannose-based mRNA targeted delivery system and application thereof |
WO2022023559A1 (en) | 2020-07-31 | 2022-02-03 | Curevac Ag | Nucleic acid encoded antibody mixtures |
CN116157525A (en) * | 2020-08-07 | 2023-05-23 | 香港科技大学 | Compositions and methods for increasing protein expression |
WO2022043551A2 (en) | 2020-08-31 | 2022-03-03 | Curevac Ag | Multivalent nucleic acid based coronavirus vaccines |
WO2022076901A1 (en) * | 2020-10-09 | 2022-04-14 | Duke University | Novel targets for reactivation of prader-willi syndrome-associated genes |
CN112280750B (en) * | 2020-10-22 | 2022-11-01 | 山东农业大学 | Novel goose astrovirus with cross-species transmission capability and application thereof |
CN112526127B (en) * | 2020-10-28 | 2022-12-06 | 四川大学华西医院 | Detection method of tetanus antigen and application thereof |
WO2022137133A1 (en) | 2020-12-22 | 2022-06-30 | Curevac Ag | Rna vaccine against sars-cov-2 variants |
CA3171051A1 (en) | 2020-12-22 | 2022-06-30 | Curevac Ag | Pharmaceutical composition comprising lipid-based carriers encapsulating rna for multidose administration |
CA3205569A1 (en) | 2020-12-22 | 2022-06-30 | CureVac SE | Rna vaccine against sars-cov-2 variants |
CN112574997B (en) * | 2021-01-17 | 2023-07-21 | 楷拓生物科技(苏州)有限公司 | Modified body of FBXW7 annular RNA and application of modified body in tumor medicaments and novel crown vaccines |
EP4087938A2 (en) | 2021-01-27 | 2022-11-16 | CureVac AG | Method of reducing the immunostimulatory properties of in vitro transcribed rna |
JP2024508707A (en) * | 2021-02-12 | 2024-02-28 | シアトル チルドレンズ ホスピタル (ディービーエイ シアトル チルドレンズ リサーチ インスティテュート) | Activity-inducing fusion protein with heat shock protein 90 binding domain |
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CN113341152B (en) * | 2021-04-27 | 2022-04-26 | 华南农业大学 | Application of RPS9 protein in prediction of good response of crab eating monkey to superovulation |
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CA3230056A1 (en) | 2021-09-03 | 2023-03-09 | Patrick Baumhof | Novel lipid nanoparticles for delivery of nucleic acids comprising phosphatidylserine |
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WO2023144193A1 (en) | 2022-01-25 | 2023-08-03 | CureVac SE | Mrnas for treatment of hereditary tyrosinemia type i |
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CN116240175B (en) * | 2023-02-28 | 2024-02-23 | 武汉科技大学 | Preparation method of chimeric anti-HIV broad-spectrum neutralizing antibody exosome and application thereof in anti-HIV infection |
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RU2717986C2 (en) * | 2013-12-30 | 2020-03-27 | Куревак Аг | Artificial molecules of nucleic acid |
ES2754239T3 (en) | 2014-03-12 | 2020-04-16 | Curevac Ag | Combination of vaccination and OX40 agonists |
CA2936286A1 (en) | 2014-04-01 | 2015-10-08 | Curevac Ag | Polymeric carrier cargo complex for use as an immunostimulating agent or as an adjuvant |
CA2962849A1 (en) | 2014-12-16 | 2016-06-23 | Curevac Ag | Ebolavirus and marburgvirus vaccines |
SG11201704681QA (en) * | 2014-12-30 | 2017-07-28 | Curevac Ag | Artificial nucleic acid molecules |
CA2975333A1 (en) | 2015-04-22 | 2016-10-27 | Curevac Ag | Rna containing composition for treatment of tumor diseases |
WO2017001058A1 (en) * | 2015-07-01 | 2017-01-05 | Curevac Ag | Method for analysis of an rna molecule |
BR112018001995A2 (en) * | 2015-08-28 | 2018-09-18 | Curevac Ag | artificial nucleic acid molecules |
EP3373965A1 (en) | 2015-11-09 | 2018-09-19 | CureVac AG | Rotavirus vaccines |
US20180312545A1 (en) | 2015-11-09 | 2018-11-01 | Curevac Ag | Optimized nucleic acid molecules |
WO2017109134A1 (en) | 2015-12-22 | 2017-06-29 | Curevac Ag | Method for producing rna molecule compositions |
SG10201913630YA (en) | 2016-02-17 | 2020-03-30 | Curevac Ag | Zika virus vaccine |
WO2018104540A1 (en) * | 2016-12-08 | 2018-06-14 | Curevac Ag | Rnas for wound healing |
EP3601576A1 (en) * | 2017-03-24 | 2020-02-05 | CureVac AG | Nucleic acids encoding crispr-associated proteins and uses thereof |
-
2018
- 2018-10-17 KR KR1020207012300A patent/KR20200071081A/en not_active Application Discontinuation
- 2018-10-17 US US16/757,289 patent/US20220233568A1/en active Pending
- 2018-10-17 SG SG11202002186VA patent/SG11202002186VA/en unknown
- 2018-10-17 RU RU2020115287A patent/RU2020115287A/en unknown
- 2018-10-17 WO PCT/EP2018/078453 patent/WO2019077001A1/en unknown
- 2018-10-17 AU AU2018351481A patent/AU2018351481A1/en active Pending
- 2018-10-17 CN CN201880067696.6A patent/CN111630173A/en active Pending
- 2018-10-17 MX MX2020003995A patent/MX2020003995A/en unknown
- 2018-10-17 EP EP18789606.3A patent/EP3697912A1/en active Pending
- 2018-10-17 JP JP2020521986A patent/JP2021501572A/en active Pending
- 2018-10-17 BR BR112020004351-6A patent/BR112020004351A2/en unknown
- 2018-10-17 CA CA3073634A patent/CA3073634A1/en active Pending
-
2020
- 2020-02-23 IL IL272850A patent/IL272850A/en unknown
-
2023
- 2023-11-06 JP JP2023189376A patent/JP2024012523A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
BR112020004351A2 (en) | 2020-09-08 |
CN111630173A (en) | 2020-09-04 |
JP2021501572A (en) | 2021-01-21 |
IL272850A (en) | 2020-04-30 |
US20220233568A1 (en) | 2022-07-28 |
RU2020115287A3 (en) | 2022-02-28 |
EP3697912A1 (en) | 2020-08-26 |
CA3073634A1 (en) | 2019-04-25 |
MX2020003995A (en) | 2020-07-22 |
KR20200071081A (en) | 2020-06-18 |
JP2024012523A (en) | 2024-01-30 |
RU2020115287A (en) | 2021-11-19 |
AU2018351481A1 (en) | 2020-03-12 |
WO2019077001A1 (en) | 2019-04-25 |
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