SG11202000390TA - Pharmaceutical combinations comprising an anti bst-1 antibody and a cytidine analogue - Google Patents

Pharmaceutical combinations comprising an anti bst-1 antibody and a cytidine analogue

Info

Publication number
SG11202000390TA
SG11202000390TA SG11202000390TA SG11202000390TA SG11202000390TA SG 11202000390T A SG11202000390T A SG 11202000390TA SG 11202000390T A SG11202000390T A SG 11202000390TA SG 11202000390T A SG11202000390T A SG 11202000390TA SG 11202000390T A SG11202000390T A SG 11202000390TA
Authority
SG
Singapore
Prior art keywords
bst
antibody
pharmaceutical combinations
cytidine analogue
cytidine
Prior art date
Application number
SG11202000390TA
Other languages
English (en)
Inventor
Cecilia Simonelli
Andrea Pellacani
Monica Binaschi
Daniela Bellaosa
Corrado Carrisi
Original Assignee
Berlin Chemie Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Berlin Chemie Ag filed Critical Berlin Chemie Ag
Publication of SG11202000390TA publication Critical patent/SG11202000390TA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/40Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41Glycosylation, sialylation, or fucosylation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732Antibody-dependent cellular cytotoxicity [ADCC]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77Internalization into the cell

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
SG11202000390TA 2017-07-21 2018-07-20 Pharmaceutical combinations comprising an anti bst-1 antibody and a cytidine analogue SG11202000390TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1711785.4A GB201711785D0 (en) 2017-07-21 2017-07-21 Antibodies
PCT/EP2018/069768 WO2019016371A1 (en) 2017-07-21 2018-07-20 PHARMACEUTICAL ASSOCIATIONS COMPRISING ANTI-BST-1 ANTIBODY AND A CYTIDINE ANALOG

Publications (1)

Publication Number Publication Date
SG11202000390TA true SG11202000390TA (en) 2020-02-27

Family

ID=59771583

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202000390TA SG11202000390TA (en) 2017-07-21 2018-07-20 Pharmaceutical combinations comprising an anti bst-1 antibody and a cytidine analogue

Country Status (22)

Country Link
US (1) US20200231694A1 (enExample)
EP (1) EP3655033A1 (enExample)
JP (1) JP2020527594A (enExample)
KR (1) KR20200032162A (enExample)
CN (1) CN111132697A (enExample)
AR (1) AR112460A1 (enExample)
AU (1) AU2018303241A1 (enExample)
BR (1) BR112020001320A2 (enExample)
CA (1) CA3070264A1 (enExample)
CL (1) CL2020000175A1 (enExample)
CO (1) CO2020001792A2 (enExample)
EA (1) EA202090333A1 (enExample)
GB (1) GB201711785D0 (enExample)
IL (1) IL272096A (enExample)
MA (1) MA49627A (enExample)
MX (1) MX2020000752A (enExample)
PH (1) PH12020550024A1 (enExample)
SG (1) SG11202000390TA (enExample)
TW (1) TW201907952A (enExample)
UY (1) UY37815A (enExample)
WO (1) WO2019016371A1 (enExample)
ZA (1) ZA202000881B (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201809746D0 (en) * 2018-06-14 2018-08-01 Berlin Chemie Ag Pharmaceutical combinations

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004063494A1 (de) * 2004-12-23 2006-07-13 Tegenero Ag Antikörper
NZ618503A (en) * 2011-06-28 2016-03-31 Oxford Biotherapeutics Ltd Antibodies to adp-ribosyl cyclase 2
GB201806084D0 (en) * 2018-04-13 2018-05-30 Berlin Chemie Ag Antibodies
EP4045083B1 (en) * 2019-10-18 2024-01-10 Forty Seven, Inc. Combination therapies for treating myelodysplastic syndromes and acute myeloid leukemia

Also Published As

Publication number Publication date
US20200231694A1 (en) 2020-07-23
ZA202000881B (en) 2021-08-25
EA202090333A1 (ru) 2020-05-06
CO2020001792A2 (es) 2020-07-31
MX2020000752A (es) 2020-08-17
GB201711785D0 (en) 2017-09-06
CA3070264A1 (en) 2019-01-24
AR112460A1 (es) 2019-10-30
TW201907952A (zh) 2019-03-01
KR20200032162A (ko) 2020-03-25
CN111132697A (zh) 2020-05-08
CL2020000175A1 (es) 2020-06-12
AU2018303241A1 (en) 2020-02-20
PH12020550024A1 (en) 2021-02-15
BR112020001320A2 (pt) 2020-08-11
UY37815A (es) 2019-02-28
MA49627A (fr) 2020-05-27
WO2019016371A1 (en) 2019-01-24
EP3655033A1 (en) 2020-05-27
IL272096A (en) 2020-03-31
JP2020527594A (ja) 2020-09-10

Similar Documents

Publication Publication Date Title
IL275737A (en) Variant antibodies against TIGIT
IL293377B1 (en) Variants of hsd17b13 and their uses
IL268206A (en) Antibodies directed against bcma and their use
GB2572126B (en) Pharmaceutical
GB2569961B (en) Pharmaceutical
GB2572125B (en) Pharmaceutical
HUE061247T2 (hu) Termékek és készítmények
SG11202009787VA (en) Modified mitochondria and use thereof
ZA202004675B (en) Pharmaceutical combinations comprising an anti-ly75 antibody
IL275577A (en) Antibodies and their variants against PD-L1
DK3334500T3 (da) Multiligand-lægemiddelskonjugater og anvendelser deraf
SG11202106067UA (en) Tubulysins and protein-tubulysin conjugates
SG11202101517PA (en) Isoquinoline-steroid conjugates and uses thereof
IL264403A (en) Vortioxetine analogue and use and preparation thereof
IL269239A (en) A pharmaceutical combination containing fonsimod
ZA201906248B (en) Anti-ceacam1 antibody and use thereof
EP3706771A4 (en) BCL9 PEPTIDES AND VARIANTS THEREOF
IL276323A (en) 4-Methyldihydropyrimidinone compounds and their pharmaceutical use
SG11202008543RA (en) Pyrrolidineamide derivatives and uses thereof
ZA202008034B (en) Ivosidenib forms and pharmaceutical compositions
GB201714409D0 (en) Oligonucleotides and analogues thereof
ZA202000881B (en) Pharmaceutical combinations comprising an anti bst-1 antibody and a cytidine analogue
IL275211A (en) Fast and flexible segment chains - division
IL273671A (en) Cornoline variants and their use
IL292646A (en) Pharmaceutical combination and its use