SG11201911971SA - Generalized stochastic super-resolution sequencing - Google Patents

Generalized stochastic super-resolution sequencing

Info

Publication number
SG11201911971SA
SG11201911971SA SG11201911971SA SG11201911971SA SG11201911971SA SG 11201911971S A SG11201911971S A SG 11201911971SA SG 11201911971S A SG11201911971S A SG 11201911971SA SG 11201911971S A SG11201911971S A SG 11201911971SA SG 11201911971S A SG11201911971S A SG 11201911971SA
Authority
SG
Singapore
Prior art keywords
resolution sequencing
generalized stochastic
stochastic super
super
generalized
Prior art date
Application number
SG11201911971SA
Inventor
Gary Mark Skinner
Geraint Wyn Evans
Stanley S Hong
Original Assignee
Illumina Cambridge Ltd
Illumina Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Illumina Cambridge Ltd, Illumina Inc filed Critical Illumina Cambridge Ltd
Publication of SG11201911971SA publication Critical patent/SG11201911971SA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6456Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458Fluorescence microscopy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6432Quenching
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • G01N2021/6441Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks with two or more labels
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6408Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6452Individual samples arranged in a regular 2D-array, e.g. multiwell plates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Optical Measuring Cells (AREA)
  • Microscoopes, Condenser (AREA)
SG11201911971SA 2018-03-09 2019-03-06 Generalized stochastic super-resolution sequencing SG11201911971SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862640909P 2018-03-09 2018-03-09
PCT/US2019/021013 WO2019173515A1 (en) 2018-03-09 2019-03-06 Generalized stochastic super-resolution sequencing

Publications (1)

Publication Number Publication Date
SG11201911971SA true SG11201911971SA (en) 2020-01-30

Family

ID=67843731

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201911971SA SG11201911971SA (en) 2018-03-09 2019-03-06 Generalized stochastic super-resolution sequencing

Country Status (13)

Country Link
US (2) US11111533B2 (en)
EP (1) EP3762507A4 (en)
JP (2) JP7143341B2 (en)
KR (1) KR102299751B1 (en)
CN (1) CN111094592A (en)
AU (2) AU2019231688B2 (en)
BR (1) BR112019027603A2 (en)
CA (1) CA3067144C (en)
IL (1) IL271411B2 (en)
MX (1) MX2019014803A (en)
RU (1) RU2739571C1 (en)
SG (1) SG11201911971SA (en)
WO (1) WO2019173515A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10829816B2 (en) 2012-11-19 2020-11-10 Apton Biosystems, Inc. Methods of analyte detection
CA2891939C (en) 2012-11-19 2020-10-27 Apton Biosystems, Inc. Digital analysis of molecular analytes using single molecule detection
EP4306650A3 (en) 2013-08-22 2024-03-27 Pacific Biosciences of California, Inc. Digital analysis of molecular analytes using electrical methods
JP7305611B2 (en) 2017-03-17 2023-07-10 アプトン バイオシステムズ インコーポレイテッド Methods of sequencing and high-resolution imaging
RU2739571C1 (en) 2018-03-09 2020-12-25 Иллюмина Кембридж Лимитед Generalized stochastic sequestration of superresolution
WO2020061237A1 (en) 2018-09-19 2020-03-26 Apton Biosystems, Inc. Densely-packed analyte layers and detection methods
US20220145379A1 (en) * 2019-12-16 2022-05-12 Illumina, Inc. Kits and flow cells
MX2021016073A (en) * 2019-12-31 2022-03-25 Illumina Inc Autofocus functionality in optical sample analysis.
US11408032B2 (en) 2020-01-17 2022-08-09 Element Biosciences, Inc. Tube lens design for improved depth-of-field
KR102654655B1 (en) 2020-10-20 2024-04-05 한양대학교 산학협력단 Method for stochastic optical reconstruction microscopy imaging and stochastic optical reconstruction microscopy imaging apparatus
KR102619825B1 (en) 2020-10-20 2024-01-03 한양대학교 산학협력단 Stochastic optical reconstruction microscopy imaging buffer solution and preparation stochastic optical reconstruction microscopy imaging methods using thereof
KR20230059684A (en) 2021-10-26 2023-05-03 한양대학교 산학협력단 Polarity sensing method of polymer thin film at single-molecule level
KR20230120819A (en) 2022-02-10 2023-08-17 한양대학교 산학협력단 Method sensing hydrogen bonds in solvents using fluorescence microscopy or stochastic optical reconstruction microscopy
WO2024122327A1 (en) * 2022-12-09 2024-06-13 ユニバーサル・バイオ・リサーチ株式会社 Gene panel sequencer and gene panel sequencing method

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2044616A1 (en) 1989-10-26 1991-04-27 Roger Y. Tsien Dna sequencing
CA2294053A1 (en) 1997-06-25 1998-12-30 Orchid Biocomputer, Inc. Methods for the detection of multiple single nucleotide polymorphisms in a single reaction
US20050191698A1 (en) 1999-04-20 2005-09-01 Illumina, Inc. Nucleic acid sequencing using microsphere arrays
GB0321306D0 (en) 2003-09-11 2003-10-15 Solexa Ltd Modified polymerases for improved incorporation of nucleotide analogues
EP2071927A2 (en) 2006-09-28 2009-06-24 Illumina, Inc. Compositions and methods for nucleotide sequencing
EP2677308B1 (en) 2006-12-14 2017-04-26 Life Technologies Corporation Method for fabricating large scale FET arrays
US8349167B2 (en) 2006-12-14 2013-01-08 Life Technologies Corporation Methods and apparatus for detecting molecular interactions using FET arrays
US8262900B2 (en) 2006-12-14 2012-09-11 Life Technologies Corporation Methods and apparatus for measuring analytes using large scale FET arrays
US7909193B2 (en) 2007-11-15 2011-03-22 Target Brands, Inc. Packaging cap
US20100137143A1 (en) 2008-10-22 2010-06-03 Ion Torrent Systems Incorporated Methods and apparatus for measuring analytes
RU2611207C2 (en) 2012-01-13 2017-02-21 Конинклейке Филипс Н.В. Dna sequencing with reagent recycling on wire grid
WO2013112999A1 (en) 2012-01-27 2013-08-01 Cornell University Methods and arrays for controlled manipulation of dna and chromatin fragments for genetic and epigenetic analysis
CN105793434B (en) * 2013-08-02 2021-08-10 Stc.Unm 公司 DNA sequencing and epigenomic analysis
CN103866010B (en) * 2014-02-28 2016-04-20 郭诚 A kind of method of gene sequencing
WO2016065300A1 (en) * 2014-10-24 2016-04-28 Eshoo Mark W Microfluidic cartridge
WO2016112999A1 (en) * 2015-01-16 2016-07-21 Longsand Limited Number of revisions of file to store based on category
WO2017087823A1 (en) * 2015-11-18 2017-05-26 Mir Kalim U Super-resolution sequencing
US20180088048A1 (en) * 2016-04-29 2018-03-29 Northwestern University Devices, methods, and systems relating to super resolution imaging
RU2739571C1 (en) 2018-03-09 2020-12-25 Иллюмина Кембридж Лимитед Generalized stochastic sequestration of superresolution

Also Published As

Publication number Publication date
BR112019027603A2 (en) 2020-11-10
AU2019231688B2 (en) 2022-03-31
MX2019014803A (en) 2021-02-09
US20210363578A1 (en) 2021-11-25
EP3762507A1 (en) 2021-01-13
KR102299751B1 (en) 2021-09-08
US12091713B2 (en) 2024-09-17
JP7143341B2 (en) 2022-09-28
US20190276886A1 (en) 2019-09-12
WO2019173515A1 (en) 2019-09-12
IL271411B1 (en) 2023-11-01
IL271411B2 (en) 2024-03-01
JP2021510292A (en) 2021-04-22
EP3762507A4 (en) 2021-11-10
US11111533B2 (en) 2021-09-07
RU2739571C1 (en) 2020-12-25
IL271411A (en) 2020-01-30
JP2022191231A (en) 2022-12-27
CN111094592A (en) 2020-05-01
CA3067144C (en) 2023-09-05
AU2022204662A1 (en) 2022-07-21
KR20200024794A (en) 2020-03-09
CA3067144A1 (en) 2019-09-12
AU2019231688A1 (en) 2020-01-02
JP7462002B2 (en) 2024-04-04

Similar Documents

Publication Publication Date Title
IL271411A (en) Generalized stochastic super-resolution sequencing
EP3411494A4 (en) Super-resolution sequencing
EP4021351C0 (en) Docking element
CA184572S (en) Document organizer
GB201807286D0 (en) New use
GB201807370D0 (en) Bend shiffener
ZA202101466B (en) Construction element
IL285396A (en) Biological sequencing
EP3973114C0 (en) Construction element
SG11202106202QA (en) Overhanging element
CA185827S (en) Book
ZAF201800650S (en) Construction element
GB2578827B (en) Swimming aid
ZA202204562B (en) Construction element
GB201908621D0 (en) Construction set
GB201820913D0 (en) St
FI12548U1 (en) Element
GB201906000D0 (en) Structural element
GB201813992D0 (en) St
ZAF201801202S (en) Construction units
ZAF201801201S (en) Construction units
GB201813486D0 (en) st
GB201813476D0 (en) st
GB201813347D0 (en) St
GB201813206D0 (en) St