SG11201908817WA - Peptide compound and method for producing same, composition for screening use, and method for selecting peptide compound - Google Patents

Peptide compound and method for producing same, composition for screening use, and method for selecting peptide compound

Info

Publication number
SG11201908817WA
SG11201908817WA SG11201908817WA SG11201908817WA SG 11201908817W A SG11201908817W A SG 11201908817WA SG 11201908817W A SG11201908817W A SG 11201908817WA SG 11201908817W A SG11201908817W A SG 11201908817WA
Authority
SG
Singapore
Prior art keywords
peptide compound
composition
selecting
screening use
producing same
Prior art date
Application number
Inventor
Masaaki Inoue
Takashi Tamura
Yuji Yoshimitsu
Takahiro Hohsaka
Takayoshi Watanabe
Original Assignee
Fujifilm Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujifilm Corp filed Critical Fujifilm Corp
Publication of SG11201908817WA publication Critical patent/SG11201908817WA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747—Apoptosis related proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • C40B40/08—Libraries containing RNA or DNA which encodes proteins, e.g. gene libraries
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/06—Biochemical methods, e.g. using enzymes or whole viable microorganisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/10—Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C07K2319/43—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a FLAG-tag
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

PEPTIDE COMPOUND AND METHOD FOR PRODUCING SAME, COMPOSITION FOR SCREENING USE, AND METHOD FOR SELECTING PEPTIDE COMPOUND An object of the present invention is to provide a novel cyclic peptide compound excellent in cell membrane permeability, a method for producing the same, a composition for screening use, and a method for selecting a cyclic peptide compound that binds to a target substance. According to the present invention, a peptide compound represented by Formula (1) or a salt thereof is provided. In the formula, the symbols have the meanings as defined in the specification of the present application. [No available figure]
SG11201908817W 2017-03-21 2018-03-20 Peptide compound and method for producing same, composition for screening use, and method for selecting peptide compound SG11201908817WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2017053954 2017-03-21
PCT/JP2018/011143 WO2018174078A1 (en) 2017-03-21 2018-03-20 Peptide compound and method for producing same, composition for screening use, and method for selecting peptide compound

Publications (1)

Publication Number Publication Date
SG11201908817WA true SG11201908817WA (en) 2019-10-30

Family

ID=63585509

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201908817W SG11201908817WA (en) 2017-03-21 2018-03-20 Peptide compound and method for producing same, composition for screening use, and method for selecting peptide compound

Country Status (12)

Country Link
US (1) US11319347B2 (en)
EP (1) EP3604326A4 (en)
JP (1) JP6831903B2 (en)
KR (1) KR20190121346A (en)
CN (1) CN110475785B (en)
AU (1) AU2018238892B2 (en)
BR (1) BR112019019829A2 (en)
CA (1) CA3057419A1 (en)
RU (1) RU2731211C1 (en)
SG (1) SG11201908817WA (en)
TW (1) TW201840582A (en)
WO (1) WO2018174078A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102243870B1 (en) * 2016-09-30 2021-04-22 후지필름 가부시키가이샤 Cyclic peptides, affinity chromatography carriers, labeled antibodies, antibody drug complexes, and pharmaceutical preparations
JP2020196706A (en) * 2019-05-29 2020-12-10 花王株式会社 Norovirus-binding peptides
CN110407744A (en) * 2019-08-13 2019-11-05 上海毕得医药科技有限公司 A kind of synthetic method of 1- (4-aminopyridine -2- base) ethyl ketone
EP4074829A4 (en) * 2019-12-12 2024-01-10 Chugai Seiyaku Kabushiki Kaisha Method for producing peptide containing non-natural amino acid
CN117794527A (en) * 2021-06-04 2024-03-29 学校法人京都药科大学 Novel AMP-activating protein kinase activators
CN117642413A (en) 2021-08-31 2024-03-01 富士胶片株式会社 Compounds and labeled biological substances using the same
JPWO2023032996A1 (en) 2021-08-31 2023-03-09
JPWO2023032995A1 (en) 2021-08-31 2023-03-09
WO2023048291A1 (en) 2021-09-24 2023-03-30 富士フイルム株式会社 tRNA, AMINOACYL-tRNA, POLYPEPTIDE SYNTHESIS REAGENT, UNNATURAL AMINO ACID INCORPORATION METHOD, POLYPEPTIDE PRODUCTION METHOD, NUCLEIC ACID DISPLAY LIBRARY PRODUCTION METHOD, NUCLEIC ACID/POLYPEPTIDE CONJUGATE, AND SCREENING METHOD
WO2024073605A2 (en) * 2022-09-29 2024-04-04 Peptidream Inc. Epha2-binding pending peptide and composition comprising same

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4917044B1 (en) 1964-07-13 1974-04-26
KR20000032823A (en) 1998-11-18 2000-06-15 이계철 Electronic bankbook system and financial service method using electronic bankbook system
US6416950B1 (en) 1998-12-02 2002-07-09 Phylos, Inc. DNA-protein fusions and uses thereof
ES2383332T3 (en) 1999-07-27 2012-06-20 Bristol-Myers Squibb Company Peptide Acceptor Ligation Procedure
WO2003002595A2 (en) * 2001-06-27 2003-01-09 Probiodrug Ag Dipeptidyl peptidase iv inhibitors and their uses as anti-cancer agents
EP1725250A2 (en) * 2004-02-18 2006-11-29 Frutarom Ltd. Method for the preparation of peptide-oligonucleotide conjugates
WO2006004841A2 (en) * 2004-06-29 2006-01-12 The Scripps Research Institute Galanin agonists
WO2007055429A1 (en) 2005-11-14 2007-05-18 Japan Science And Technology Agency MUTANT tRNA FOR INTRODUCING UNNATURAL AMINO ACID INTO PROTEIN
WO2009096541A1 (en) * 2008-02-01 2009-08-06 Ajinomoto Co., Inc. Method of producing cysteine derivative
WO2010033617A2 (en) 2008-09-16 2010-03-25 The Research Foundation Of State University Of New York Stapled peptides and method of synthesis
US20110213124A1 (en) * 2010-02-26 2011-09-01 Gryshuk Amy L Methods and systems for synthesis of a d-aminoluciferin precursor and related compounds
JP5818237B2 (en) 2010-09-09 2015-11-18 国立大学法人 東京大学 Translational construction and search for active species of special peptide compound library containing N-methylamino acid and other special amino acids
WO2012075048A2 (en) 2010-11-30 2012-06-07 The Johns Hopkins University Hybrid cyclic libraries and screens thereof
WO2012083078A2 (en) 2010-12-15 2012-06-21 The Research Foundation Of State University Of New York Croos-linked peptides and proteins, methods of making same, and uses thereof
US9642922B2 (en) 2013-08-23 2017-05-09 The Board Of Trustees Of The Leland Stanford Junior University Caspase-triggered nano-aggregation probes and methods of use
WO2016144665A1 (en) * 2015-03-06 2016-09-15 Colorado State University Research Foundation Method for preparing largazole analogs and uses thereof

Also Published As

Publication number Publication date
TW201840582A (en) 2018-11-16
EP3604326A1 (en) 2020-02-05
CA3057419A1 (en) 2018-09-27
CN110475785A (en) 2019-11-19
WO2018174078A1 (en) 2018-09-27
AU2018238892B2 (en) 2020-07-23
EP3604326A4 (en) 2020-12-16
US11319347B2 (en) 2022-05-03
JP6831903B2 (en) 2021-02-17
RU2731211C1 (en) 2020-08-31
KR20190121346A (en) 2019-10-25
US20200040039A1 (en) 2020-02-06
CN110475785B (en) 2023-06-13
JPWO2018174078A1 (en) 2020-01-30
AU2018238892A1 (en) 2019-10-17
BR112019019829A2 (en) 2020-04-22

Similar Documents

Publication Publication Date Title
SG11201908817WA (en) Peptide compound and method for producing same, composition for screening use, and method for selecting peptide compound
PH12019500540A1 (en) Anti-pd-1 antibodies and their uses
MX2017014699A (en) Novel polypeptides.
SG10201914126RA (en) Anti-ox40 antibodies and their uses
NZ706189A (en) Monoclonal antibodies to growth and differentiation factor 15 (gdf-15)
EA201890752A1 (en) METHOD OF OBTAINING ANTI-FIBER CONNECTIONS
MX2019011778A (en) Composition for tagatose production and method for tagatose production using same.
PH12016500643B1 (en) NEW OCTAHYDRO-CYCLOBUTA [1,2-c;3,4-c'] DIPYRROL-2-YL
MX2022000893A (en) Method of obtaining mitochondria from cells and obtained mitochondria.
MX2019011758A (en) Composition for tagatose production and method for tagatose production using same.
PH12020550703A1 (en) Sulfonamide compounds and use thereof
MX2019013419A (en) Bicyclic pesticidal compounds.
MX2020006370A (en) Pyrazolopyridine-diamides, their use as insecticide and processes for preparing the same.
WO2017064627A3 (en) Process for preparation of eribulin and intermediates thereof
EA201991311A1 (en) PHENYLAMIDINES AND THEIR APPLICATION AS FUNGICIDES
EA201400214A1 (en) Anthranilamide compounds and their use as pesticides
EA201400215A1 (en) Anthranilamide compounds and their use as pesticides
EA201890177A1 (en) MULTI-SPECIFIC BINDING PROTEINS
EA201990270A1 (en) MIXTURES CONTAINING DEFI AND TAURATAMIDES, AND METHODS FOR PRODUCING THERE
MX2019002620A (en) Methods of chemical synthesis of diaminophenothiazinium compounds including methylthioninium chloride (mtc).
WO2016014864A8 (en) Hydroxy-(r),(r)-2,2'-bismethylnaltrexones and uses thereof
MX2013006813A (en) Lactone compounds and materials made therefrom.
EA201991354A1 (en) PHENOXYPHENYLAMIDINES AND THEIR APPLICATION AS FUNGICIDES
PH12017501869A1 (en) (s)-2'-vinyl-abscisic acid derivatives
MX2021015879A (en) Constrained peptides.