SG11201903840WA - Method - Google Patents
MethodInfo
- Publication number
- SG11201903840WA SG11201903840WA SG11201903840WA SG11201903840WA SG11201903840WA SG 11201903840W A SG11201903840W A SG 11201903840WA SG 11201903840W A SG11201903840W A SG 11201903840WA SG 11201903840W A SG11201903840W A SG 11201903840WA SG 11201903840W A SG11201903840W A SG 11201903840WA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- oxford
- headington
- vpci
- level
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 208000035868 Vascular inflammations Diseases 0.000 abstract 2
- 239000000090 biomarker Substances 0.000 abstract 2
- 230000000747 cardiac effect Effects 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 244000028344 Primula vulgaris Species 0.000 abstract 1
- 235000016311 Primula vulgaris Nutrition 0.000 abstract 1
- 210000004204 blood vessel Anatomy 0.000 abstract 1
- 238000002591 computed tomography Methods 0.000 abstract 1
- 230000008520 organization Effects 0.000 abstract 1
- 208000019553 vascular disease Diseases 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T11/00—2D [Two Dimensional] image generation
- G06T11/003—Reconstruction from projections, e.g. tomography
- G06T11/008—Specific post-processing after tomographic reconstruction, e.g. voxelisation, metal artifact correction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
- A61B6/03—Computed tomography [CT]
- A61B6/032—Transmission computed tomography [CT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/50—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications
- A61B6/504—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications for diagnosis of blood vessels, e.g. by angiography
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/52—Devices using data or image processing specially adapted for radiation diagnosis
- A61B6/5211—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data
- A61B6/5217—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data extracting a diagnostic or physiological parameter from medical diagnostic data
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/0002—Inspection of images, e.g. flaw detection
- G06T7/0012—Biomedical image inspection
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/60—Analysis of geometric attributes
- G06T7/62—Analysis of geometric attributes of area, perimeter, diameter or volume
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H30/00—ICT specially adapted for the handling or processing of medical images
- G16H30/40—ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/10—Image acquisition modality
- G06T2207/10072—Tomographic images
- G06T2207/10081—Computed x-ray tomography [CT]
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/30—Subject of image; Context of image processing
- G06T2207/30004—Biomedical image processing
- G06T2207/30048—Heart; Cardiac
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/30—Subject of image; Context of image processing
- G06T2207/30004—Biomedical image processing
- G06T2207/30101—Blood vessel; Artery; Vein; Vascular
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
Landscapes
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Medical Informatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Theoretical Computer Science (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Computer Vision & Pattern Recognition (AREA)
- General Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Optics & Photonics (AREA)
- High Energy & Nuclear Physics (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Primary Health Care (AREA)
- Epidemiology (AREA)
- Quality & Reliability (AREA)
- Geometry (AREA)
- Pulmonology (AREA)
- Dentistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Vascular Medicine (AREA)
- Physiology (AREA)
- Data Mining & Analysis (AREA)
- Databases & Information Systems (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Medical Treatment And Welfare Office Work (AREA)
Abstract
FAIPVATB) - FAIPVAT FAIPVAT y -82 c ' - e ) -84 -86 - 88 FAIPVAT (FAIPVAr - FAInan-PVAT) Distance from the RCA wall (mm) VPCI-100x Attenuation map (HU) Water Fat LaFF4 +15 -15 -20 -190 in (A) D VPCI (%) FPI tertiles — Low -- Mid ---- High FIGURE 1 W O 20 18/07 8395 Al VPCI (%) VPCI (/r) 2 4 6 8 10 12 14 16 18 20 (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 03 May 2018 (03.05.2018) WIPO I PCT omit ° oI0IIIIIIIIIIV111mull oimIE (10) International Publication Number WO 2018/078395 Al (51) International Patent Classification: A61B 6/03 (2006.01) GO6T 7/62 (2017.01) GO6T 7/00 (2017.01) (21) International Application Number: PCT/GB2017/053262 (22) International Filing Date: 31 October 2017 (31.10.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 20160100555 31 October 2016 (31.10.2016) GR 1620494.3 02 December 2016 (02.12.2016) GB (71) Applicant: OXFORD UNIVERSITY INNOVATION LIMITED [GB/GB]; Buxton Court, 3 West Way, Botley OX2 OSZ (GB). (72) Inventors: ANTONIADES, Charalambos; Level 6 West Wing, John Radcliffe Hospital, Headington, Oxford OX3 9DU (GB). CHANNON, Keith; Level 6 West Wing, John Radcliffe Hospital, Headington, Oxford OX3 9DU (GB). OIKONOMOU, Evangelos; Level 6 West Wing, John Radcliffe Hospital, Headington, Oxford OX3 9DU (GB). NEUBAUER, Stefan; Level 6 West Wing, John Radcliffe Hospital, Headington, Oxford OX3 9DU (GB). (74) Agent: GILL JENNINGS & EVERY LLP et al.; The Broadgate Tower, 20 Primrose Street, London Greater Lon- don EC2A 2ES (GB). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, (54) Title: METHOD (57) : The present invention describes a new functional bio- marker of vascular inflammation and its use in predicting all-cause or cardiac mortality. The invention also provides a method for stratifying patients according to their risk of all-cause or cardiac mortality using data gathered from a computer tomography scans of a blood vessel to determine a specific combination of structural and functional bio- markers of vascular inflammation and disease. [Continued on next page] WO 2018/078395 Al MIDEDIMOMMIDIREIDINIMIERIMEMOVOIS TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3))
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GR20160100555 | 2016-10-31 | ||
| GB1620494.3A GB2557263A (en) | 2016-12-02 | 2016-12-02 | Method |
| PCT/GB2017/053262 WO2018078395A1 (en) | 2016-10-31 | 2017-10-31 | Method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201903840WA true SG11201903840WA (en) | 2019-05-30 |
Family
ID=60201620
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201903840WA SG11201903840WA (en) | 2016-10-31 | 2017-10-31 | Method |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US11393137B2 (en) |
| EP (2) | EP3960087B1 (en) |
| JP (1) | JP7210463B2 (en) |
| KR (1) | KR102487832B1 (en) |
| CN (2) | CN117918872A (en) |
| AU (2) | AU2017351986B2 (en) |
| CA (2) | CA3226114A1 (en) |
| ES (2) | ES2938857T3 (en) |
| HU (1) | HUE063284T2 (en) |
| RU (1) | RU2758548C2 (en) |
| SG (1) | SG11201903840WA (en) |
| WO (1) | WO2018078395A1 (en) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11393137B2 (en) | 2016-10-31 | 2022-07-19 | Oxford University Innovation Limited | Method for predicting cardiovascular risk |
| GB2577349B (en) * | 2018-09-18 | 2023-06-14 | Univ Oxford Innovation Ltd | Radiomic signature of adipose |
| GB2578485A (en) * | 2018-09-18 | 2020-05-13 | Univ Oxford Innovation Ltd | Radiomic signature of a perivascular region |
| WO2020081686A1 (en) * | 2018-10-17 | 2020-04-23 | Heartflow, Inc. | Systems and methods for assessing cardiovascular disease and treatment effectiveness from adipose tissue |
| US10813612B2 (en) * | 2019-01-25 | 2020-10-27 | Cleerly, Inc. | Systems and method of characterizing high risk plaques |
| US11508063B2 (en) * | 2019-08-05 | 2022-11-22 | Elucid Bioimaging Inc. | Non-invasive measurement of fibrous cap thickness |
| EP3828817B1 (en) * | 2019-11-28 | 2023-08-23 | Siemens Healthcare GmbH | Computer-implemented method for evaluating a ct data set regarding perivascular tissue, evaluation device, computer program and electronically readable storage medium |
| JP2023509514A (en) | 2020-01-07 | 2023-03-08 | クリールリー、 インコーポレーテッド | Systems, Methods, and Devices for Medical Image Analysis, Diagnosis, Severity Classification, Decision Making, and/or Disease Tracking |
| CN111150490B (en) * | 2020-01-15 | 2021-01-29 | 陈挺 | Intelligent assistant system for cardiac radio frequency ablation surgery based on AR and AI technologies |
| RU2738135C1 (en) * | 2020-02-11 | 2020-12-08 | Общество с ограниченной ответственностью "Научно-технический центр "МТ" (ООО "НТЦ-МТ") | Dual energy roentgenography method (embodiments) |
| CN111738986B (en) * | 2020-06-01 | 2021-02-09 | 数坤（北京）网络科技有限公司 | Fat attenuation index generation method and device and computer readable medium |
| WO2023000039A1 (en) * | 2021-07-23 | 2023-01-26 | Navier Medical Ltd | Systems and methods for detecting microcalcification activity |
| US20230289963A1 (en) | 2022-03-10 | 2023-09-14 | Cleerly, Inc. | Systems, devices, and methods for non-invasive image-based plaque analysis and risk determination |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080108894A1 (en) * | 2004-11-15 | 2008-05-08 | Elgavish Gabriel A | Methods and Systems of Analyzing Clinical Parameters and Methods of Producing Visual Images |
| US20100278405A1 (en) * | 2005-11-11 | 2010-11-04 | Kakadiaris Ioannis A | Scoring Method for Imaging-Based Detection of Vulnerable Patients |
| WO2010071896A2 (en) * | 2008-12-19 | 2010-06-24 | Piedmont Healthcare, Inc. | System and method for lesion-specific coronary artery calcium quantification |
| WO2011069120A1 (en) * | 2009-12-03 | 2011-06-09 | Cedars-Sinai Medical Center | Method and system for plaque characterization |
| US8532360B2 (en) * | 2010-04-20 | 2013-09-10 | Atheropoint Llc | Imaging based symptomatic classification using a combination of trace transform, fuzzy technique and multitude of features |
| WO2014197460A1 (en) * | 2013-06-04 | 2014-12-11 | The Trustees Of The University Of Pennsylvania | Methods for diagnosing and treating bicuspid aortic valve and/or aortopathies |
| WO2015073977A1 (en) | 2013-11-15 | 2015-05-21 | The Johns Hopkins University | Systems and methods of assessing risk of sudden cardiac death |
| EP2927692B1 (en) * | 2014-04-04 | 2017-09-27 | Winfried März | Multiple biomarker approach for prediction of mortality in dialysis patients |
| GB201414496D0 (en) * | 2014-08-15 | 2014-10-01 | Isis Innovation | Method |
| US11393137B2 (en) | 2016-10-31 | 2022-07-19 | Oxford University Innovation Limited | Method for predicting cardiovascular risk |
-
2017
- 2017-10-31 US US16/345,165 patent/US11393137B2/en active Active
- 2017-10-31 ES ES17792171T patent/ES2938857T3/en active Active
- 2017-10-31 CN CN202310836385.4A patent/CN117918872A/en active Pending
- 2017-10-31 EP EP21198980.1A patent/EP3960087B1/en active Active
- 2017-10-31 CA CA3226114A patent/CA3226114A1/en active Pending
- 2017-10-31 CN CN201780081809.3A patent/CN110267596B/en active Active
- 2017-10-31 KR KR1020197015673A patent/KR102487832B1/en active IP Right Grant
- 2017-10-31 JP JP2019546092A patent/JP7210463B2/en active Active
- 2017-10-31 SG SG11201903840WA patent/SG11201903840WA/en unknown
- 2017-10-31 WO PCT/GB2017/053262 patent/WO2018078395A1/en unknown
- 2017-10-31 EP EP17792171.5A patent/EP3531917B1/en active Active
- 2017-10-31 HU HUE21198980A patent/HUE063284T2/en unknown
- 2017-10-31 CA CA3040391A patent/CA3040391A1/en active Pending
- 2017-10-31 AU AU2017351986A patent/AU2017351986B2/en active Active
- 2017-10-31 ES ES21198980T patent/ES2952254T3/en active Active
- 2017-10-31 RU RU2019112787A patent/RU2758548C2/en active
-
2021
- 2021-11-11 US US17/454,540 patent/US11880916B2/en active Active
-
2022
- 2022-12-07 US US18/062,829 patent/US11948230B2/en active Active
- 2022-12-12 AU AU2022287535A patent/AU2022287535B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2017351986A1 (en) | 2019-05-02 |
| US11948230B2 (en) | 2024-04-02 |
| US20190287276A1 (en) | 2019-09-19 |
| KR102487832B1 (en) | 2023-01-12 |
| US11393137B2 (en) | 2022-07-19 |
| RU2019112787A3 (en) | 2021-02-05 |
| AU2022287535A1 (en) | 2023-02-02 |
| EP3531917B1 (en) | 2023-01-25 |
| CN117918872A (en) | 2024-04-26 |
| AU2022287535B2 (en) | 2024-03-14 |
| CA3226114A1 (en) | 2018-05-03 |
| AU2017351986B2 (en) | 2022-12-08 |
| KR20190072633A (en) | 2019-06-25 |
| CN110267596B (en) | 2024-04-02 |
| RU2019112787A (en) | 2020-11-30 |
| CA3040391A1 (en) | 2018-05-03 |
| EP3960087A1 (en) | 2022-03-02 |
| ES2938857T3 (en) | 2023-04-17 |
| JP2020501850A (en) | 2020-01-23 |
| WO2018078395A1 (en) | 2018-05-03 |
| ES2952254T3 (en) | 2023-10-30 |
| HUE063284T2 (en) | 2024-01-28 |
| RU2758548C2 (en) | 2021-10-29 |
| JP7210463B2 (en) | 2023-01-23 |
| US20230113005A1 (en) | 2023-04-13 |
| US20220139005A1 (en) | 2022-05-05 |
| US11880916B2 (en) | 2024-01-23 |
| EP3531917A1 (en) | 2019-09-04 |
| CN110267596A (en) | 2019-09-20 |
| EP3960087B1 (en) | 2023-07-12 |
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