SG11201807835RA - An injector with reduced break loose force - Google Patents

Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -, Organization 111111110111101110101011111010111110111011111111100111011101111101111011111 International Bureau 0.. .... .. (10) International Publication Number (43) International Publication Date ..... ..or::,„, 21 September 2017 (21.09.2017) WIP0 I PCT WO 2017/157396 Al (51) International Patent Classification: BZ, A61M 5/315 (2006.01) DO, HN, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, (21) International Application Number: KP, PCT/DK2017/050070 MD, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, (22) International Filing Date: NI, 13 March 2017 (13.03.2017) RU, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, (25) Filing Language: English ZA, ZM, ZW. (26) Publication Language: English (84) Designated States (unless otherwise indicated, for every (30) Priority Data: kind PA 2016 00154 13 March 2016 (13.03.2016) DK GM, of regional protection available): ARIPO (BW, GH, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, PA 2016 00198 3 April 2016 (03.04.2016) DK TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, PA 2016 70589 8 August 2016 (08.08.2016) DK TJ, DK, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, (71) Applicant: TINA HETTING HOLDING APS [DK/DK]; LV, Strandvejen 251 B, 2920 Charlottenlund (DK). SM, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). (72) Inventor: HETTING, Mikael; Strandvejen 251 B, 2920 Charlottenlund (DK). Published: (74) Agents: HEEBOLL-NIELSEN, Anders et al.; Awapatent — with international search report (Art. 21(3)) A/S, Strandgade 56, 1401 Kobenhavn K (DK). — before the expiration of the time limit for amending the — Designated States (unless otherwise indicated, for every claims and to be republished in the event of receipt of (81) kind of national protection available): AE, AG, AL, AM, amendments (Rule 48.2(h)) AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, = = Title: AN INJECTOR WITH REDUCED BREAK LOOSE FORCE (54) (57) : The present invention relates to an injector for delivery of a pharmaceutical composi- tion, the injector comprising - a cylinder extending = = along a longitudinal axis, the cylinder having an in- 3 N__ ner wall, an outer wall, and an outlet at an outlet end opposite an actuating end, - a piston assembly com- prising a compressible section between an actuating = _ 4 — = 32-----________ / 4 .. ___---321 piston element and a passive piston element, which piston elements abut the inner wall of the cylinder at = = 8 abutting interfaces thereby sealing the compressible section when the piston assembly is inserted in the = cylinder, the compressible section comprising a compressible fluid and a resilient frame linking the actuating piston element to the passive piston ele- — 31----____________ , 5 = 33-----________ 34 ment. The injector is suited for pre-filled injectors _ 36 __ 35 allowing long term storage of protein based pharma- ceutical compositions. 1-1 C:r M IN ir) Fig. 2 Il IN Il 0 ei O