SG11201807694WA - Methods and systems for assessing infertility and ovulatory function disorders - Google Patents
Methods and systems for assessing infertility and ovulatory function disordersInfo
- Publication number
- SG11201807694WA SG11201807694WA SG11201807694WA SG11201807694WA SG11201807694WA SG 11201807694W A SG11201807694W A SG 11201807694WA SG 11201807694W A SG11201807694W A SG 11201807694WA SG 11201807694W A SG11201807694W A SG 11201807694WA SG 11201807694W A SG11201807694W A SG 11201807694WA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- new york
- methods
- assessing
- systems
- Prior art date
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
- G16B5/20—Probabilistic models
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medical Informatics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Theoretical Computer Science (AREA)
- Bioinformatics & Computational Biology (AREA)
- Evolutionary Biology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Molecular Biology (AREA)
- Physiology (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Probability & Statistics with Applications (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Pathology (AREA)
- Databases & Information Systems (AREA)
- Primary Health Care (AREA)
- Epidemiology (AREA)
- Data Mining & Analysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
Abstract
INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -, Organization MINII111011101 01011111 010 11111 01110111 11111 11111 010 111110 11111111111 00 1111 International Bureau 0.. .... .. ...... ... (10) International Publication Number (43) International Publication Date WO 2017/156279 A3 14 September 2017 (14.09.2017) WIP0 I PCT (51) International Patent Classification: AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, C12Q 1/68 (2006.01) G01N 33/50 (2006.01) BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, G01N 33/53 (2006.01) DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, (21) International Application Number: KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, PCT/US2017/021583 MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, (22) International Filing Date: NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, 9 March 2017 (09.03.2017) RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, (25) Filing Language: English ZA, ZM, ZW. (26) Publication Language: English (84) Designated States (unless otherwise indicated, for every (30) Priority Data: kind of regional protection available): ARIPO (BW, GH, 62/306,027 9 March 2016 (09.03.2016) US GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, (71) Applicant: CELMATIX INC. [US/US]; 14 Wall St, Suite TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, 16d, New York, NY 10005 (US). DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, (72) Inventors: BEIM, Piraye, Yurttas; 70 Little West Street, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, Phlb, New York, NY 10004 (US). PARFITT, David, GW, KM, ML, MR, NE, SN, TD, TG). Emlyn; 54 West 40th Street, New York, NY 10018 (US). HU-SELIGER, Tina; 146 East 49th Street, Apartment 5b, Published: New York, NY 10017 (US). SANTISTEVAN, Anthony; with international search report (Art. 21(3)) = 3505 Broadway, Apartment 36, New York, NY 10031 before limit (US). — the expiration of the time for amending the be in claims and to republished the event of receipt of = (74) Agents: MEYERS, Thomas, C. et al.; Brown Rudnick amendments (Rule 48.2(h)) LLP, One Financial Center, Boston, MA 02111 (US). (88) Date of publication of the international search report: (81) Designated States (unless otherwise indicated, for every 19 October 2017 kind of national protection available): AE, AG, AL, AM, = = = = = = = = = M C:7 IN ei ,tD in (54) Title: METHODS AND SYSTEMS FOR ASSESSING INFERTILITY AND OVULATORY FUNCTION DISORDERS Il ---.. (57) : The present invention relates to methods and systems for assessing risk of infertility and ovarian dysfunction and/or diminished ovarian reserve and/or for determining an appropriate course of treatment. In some embodiments, the invention provides Il C methods for assessing likelihood of ovarian dysfunction, including identifying a plurality of genetic variants that are filtered into N functional biological pathways. The frequency distribution of the variants in each functional pathway is then compared to frequency 0 distributions obtained from reference sets corresponding to each pathway. Further embodiments of the invention comprise clustering subjects based on patterns in their genetic variants, and identifying phenotypic differences with respect to ovarian dysfunction between clusters of patients.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662306027P | 2016-03-09 | 2016-03-09 | |
PCT/US2017/021583 WO2017156279A2 (en) | 2016-03-09 | 2017-03-09 | Methods and systems for assessing infertility and ovulatory function disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201807694WA true SG11201807694WA (en) | 2018-10-30 |
Family
ID=59786764
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201807694WA SG11201807694WA (en) | 2016-03-09 | 2017-03-09 | Methods and systems for assessing infertility and ovulatory function disorders |
Country Status (7)
Country | Link |
---|---|
US (1) | US20170262580A1 (en) |
EP (1) | EP3430165A4 (en) |
AU (1) | AU2017229787A1 (en) |
CA (1) | CA3017195A1 (en) |
IL (1) | IL261656A (en) |
SG (1) | SG11201807694WA (en) |
WO (2) | WO2017156291A1 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2019060882A1 (en) * | 2017-09-25 | 2019-03-28 | Letterie Gerard | System for supporting clinical decision-making in reproductive endocrinology and infertility |
US10552957B2 (en) * | 2018-03-24 | 2020-02-04 | Dan Nayot | Methods and systems for determining quality of an oocyte |
WO2020180424A1 (en) | 2019-03-04 | 2020-09-10 | Iocurrents, Inc. | Data compression and communication using machine learning |
RU2761982C1 (en) * | 2021-02-01 | 2021-12-14 | Екатерина Дмитриевна Дубинская | Method for personalised treatment of ovarian endometriosis in women of reproductive age based on a point diagnostic system |
CN113189334B (en) * | 2021-04-27 | 2022-04-26 | 华南农业大学 | Application of COMT protein in prediction of good response of crab eating monkey to superovulation |
IL305090A (en) | 2021-06-10 | 2023-10-01 | Alife Health Inc | Machine learning for optimizing ovarian stimulation |
CN114936662A (en) * | 2022-02-18 | 2022-08-23 | 北京大学第三医院(北京大学第三临床医学院) | System for predicting ovarian hyperresponsiveness of subject |
CN114774413B (en) * | 2022-03-18 | 2024-01-30 | 中国水产科学研究院北戴河中心实验站 | Construction method, detection method and application of zebra fish egg-laying obstacle model |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2780430A1 (en) * | 2009-11-10 | 2011-05-19 | Gema Diagnostics, Inc. | Genes differentially expressed by cumulus cells and assays using same to identify pregnancy competent oocytes |
US20140171337A1 (en) * | 2012-12-14 | 2014-06-19 | Celmatix, Inc. | Methods and devices for assessing risk of female infertility |
US9836577B2 (en) * | 2012-12-14 | 2017-12-05 | Celmatix, Inc. | Methods and devices for assessing risk of female infertility |
JP2017510250A (en) * | 2014-01-27 | 2017-04-13 | セルマティックス, インコーポレイテッド | Methods for assessing whether a genetic region is associated with infertility |
US20170362654A1 (en) * | 2014-12-09 | 2017-12-21 | The Trustees Of Princeton University | Biomarkers of oocyte quality |
WO2017070258A1 (en) * | 2015-10-19 | 2017-04-27 | Celmatix Inc. | Methods and systems for assessing infertility as a result of declining ovarian reserve and function |
-
2017
- 2017-03-09 US US15/454,726 patent/US20170262580A1/en not_active Abandoned
- 2017-03-09 EP EP17764102.4A patent/EP3430165A4/en not_active Withdrawn
- 2017-03-09 WO PCT/US2017/021605 patent/WO2017156291A1/en active Application Filing
- 2017-03-09 AU AU2017229787A patent/AU2017229787A1/en not_active Abandoned
- 2017-03-09 SG SG11201807694WA patent/SG11201807694WA/en unknown
- 2017-03-09 CA CA3017195A patent/CA3017195A1/en not_active Abandoned
- 2017-03-09 WO PCT/US2017/021583 patent/WO2017156279A2/en active Application Filing
-
2018
- 2018-09-06 IL IL261656A patent/IL261656A/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2017156279A2 (en) | 2017-09-14 |
WO2017156291A1 (en) | 2017-09-14 |
AU2017229787A1 (en) | 2018-09-27 |
IL261656A (en) | 2018-10-31 |
EP3430165A2 (en) | 2019-01-23 |
EP3430165A4 (en) | 2020-01-08 |
WO2017156279A3 (en) | 2017-10-19 |
US20170262580A1 (en) | 2017-09-14 |
CA3017195A1 (en) | 2017-09-14 |
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