SG11201805083WA - Process for epoxidation of unsaturated polymer - Google Patents

Process for epoxidation of unsaturated polymer

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Publication number
SG11201805083WA
SG11201805083WA SG11201805083WA SG11201805083WA SG11201805083WA SG 11201805083W A SG11201805083W A SG 11201805083WA SG 11201805083W A SG11201805083W A SG 11201805083WA SG 11201805083W A SG11201805083W A SG 11201805083WA SG 11201805083W A SG11201805083W A SG 11201805083WA
Authority
SG
Singapore
Prior art keywords
ontario
international
require
unsaturated polymer
london
Prior art date
Application number
SG11201805083WA
Inventor
Brianna Binder
Sarah Elliott
Gregory J E Davidson
Sharon Guo
Original Assignee
Arlanxeo Singapore Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arlanxeo Singapore Pte Ltd filed Critical Arlanxeo Singapore Pte Ltd
Publication of SG11201805083WA publication Critical patent/SG11201805083WA/en

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    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment
    • C08F8/08Epoxidation
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08CTREATMENT OR CHEMICAL MODIFICATION OF RUBBERS
    • C08C19/00Chemical modification of rubber
    • C08C19/04Oxidation
    • C08C19/06Epoxidation
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F210/00Copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond
    • C08F210/04Monomers containing three or four carbon atoms
    • C08F210/08Butenes
    • C08F210/10Isobutene
    • C08F210/12Isobutene with conjugated diolefins, e.g. butyl rubber
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment
    • C08F8/18Introducing halogen atoms or halogen-containing groups
    • C08F8/20Halogenation
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00Processes of treating or compounding macromolecular substances
    • C08J3/20Compounding polymers with additives, e.g. colouring
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00Processes of treating or compounding macromolecular substances
    • C08J3/20Compounding polymers with additives, e.g. colouring
    • C08J3/22Compounding polymers with additives, e.g. colouring using masterbatch techniques
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08KUse of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00Use of organic ingredients
    • C08K5/04Oxygen-containing compounds
    • C08K5/14Peroxides
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L15/00Compositions of rubber derivatives
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L23/00Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
    • C08L23/02Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers not modified by chemical after-treatment
    • C08L23/18Homopolymers or copolymers of hydrocarbons having four or more carbon atoms
    • C08L23/20Homopolymers or copolymers of hydrocarbons having four or more carbon atoms having four to nine carbon atoms
    • C08L23/22Copolymers of isobutene; Butyl rubber ; Homo- or copolymers of other iso-olefins
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L23/00Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
    • C08L23/26Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers modified by chemical after-treatment
    • C08L23/28Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers modified by chemical after-treatment by reaction with halogens or compounds containing halogen
    • C08L23/283Halogenated homo- or copolymers of iso-olefins
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2810/00Chemical modification of a polymer
    • C08F2810/50Chemical modification of a polymer wherein the polymer is a copolymer and the modification is taking place only on one or more of the monomers present in minority
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2323/00Characterised by the use of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Derivatives of such polymers
    • C08J2323/02Characterised by the use of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Derivatives of such polymers not modified by chemical after treatment
    • C08J2323/18Homopolymers or copolymers of hydrocarbons having four or more carbon atoms
    • C08J2323/20Homopolymers or copolymers of hydrocarbons having four or more carbon atoms having four to nine carbon atoms
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2409/00Characterised by the use of homopolymers or copolymers of conjugated diene hydrocarbons
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2409/00Characterised by the use of homopolymers or copolymers of conjugated diene hydrocarbons
    • C08J2409/06Copolymers with styrene
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2423/00Characterised by the use of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Derivatives of such polymers
    • C08J2423/02Characterised by the use of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Derivatives of such polymers not modified by chemical after treatment
    • C08J2423/18Homopolymers or copolymers of hydrocarbons having four or more carbon atoms
    • C08J2423/20Homopolymers or copolymers of hydrocarbons having four or more carbon atoms having four to nine carbon atoms
    • C08J2423/22Copolymers of isobutene; butyl rubber
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2423/00Characterised by the use of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Derivatives of such polymers
    • C08J2423/26Characterised by the use of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Derivatives of such polymers modified by chemical after-treatment
    • C08J2423/28Characterised by the use of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Derivatives of such polymers modified by chemical after-treatment by reaction with halogens or halogen-containing compounds
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00Processes of treating or compounding macromolecular substances
    • C08J3/20Compounding polymers with additives, e.g. colouring
    • C08J3/203Solid polymers with solid and/or liquid additives
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00Processes of treating or compounding macromolecular substances
    • C08J3/20Compounding polymers with additives, e.g. colouring
    • C08J3/22Compounding polymers with additives, e.g. colouring using masterbatch techniques
    • C08J3/226Compounding polymers with additives, e.g. colouring using masterbatch techniques using a polymer as a carrier

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)

Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 22 June 2017 (22.06.2017) WIPO I PCT (10) International Publication Number WO 2017/100922 Al 1111111111111101110101011111010111110 01011111110111010111011111111111110111111 (51) International Patent Classification: C08F 8/08 (2006.01) C08F 210/12 (2006.01) CO8F 10/10 (2006.01) C08C 19/06 (2006.01) (21) International Application Number: PCT/CA2016/051477 (22) International Filing Date: 14 December 2016 (14.12.2016) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 15200726.6 17 December 2015 (17.12.2015) EP (71) Applicant: ARLANXEO CANADA INC. [CA/CA]; 1265 Vidal Street South, Sarnia, Ontario N7T 7M2 (CA). (72) Inventors: BINDER, Brianna; 71 King Street, Apartment #2309, London, Ontario N6A 0A5 (CA). ELLIOTT, Sarah; 776350 Blandford Road, Bright, Ontario NOJ 1B0 (CA). DAVIDSON, Gregory J. E.; 19 Meadowridge Cres- cent, London, Ontario N6H 5G1 (CA). GUO, Sharon; 589 Firefly Drive, London, Ontario N5X 0E2 (CA). (74) Agent: BRUNET & CO. LTD.; 401 Bay St., Suite 1600, Toronto, Ontario M5H 2Y4 (CA). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) W O 20 17 / 1009 22 Al (54) Title: PROCESS FOR EPDXIDATION OF UNSATURATED POLYMER (57) : A process for epoxidation of an unsaturated polymer involves mixing an unsaturated polymer and a peroxy acid in an absence of solvent to produce an epoxidized polymer. The process may require no solvent, require no catalyst, require no or little ap - plied external heat input, require no applied cooling, require less epoxidation agent, be faster and/or result in more efficient conver- sion of the unsaturated polymer.
SG11201805083WA 2015-12-17 2016-12-14 Process for epoxidation of unsaturated polymer SG11201805083WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15200726.6A EP3181596A1 (en) 2015-12-17 2015-12-17 Process for epoxidation of unsaturated polymer
PCT/CA2016/051477 WO2017100922A1 (en) 2015-12-17 2016-12-14 Process for epoxidation of unsaturated polymer

Publications (1)

Publication Number Publication Date
SG11201805083WA true SG11201805083WA (en) 2018-07-30

Family

ID=55174496

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201805083WA SG11201805083WA (en) 2015-12-17 2016-12-14 Process for epoxidation of unsaturated polymer

Country Status (10)

Country Link
US (1) US10774158B2 (en)
EP (2) EP3181596A1 (en)
JP (1) JP6873135B2 (en)
KR (1) KR20180095033A (en)
CN (2) CN113461840A (en)
CA (1) CA3008290C (en)
RU (1) RU2742375C2 (en)
SA (1) SA518391860B1 (en)
SG (1) SG11201805083WA (en)
WO (1) WO2017100922A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3181598A1 (en) 2015-12-17 2017-06-21 Lanxess Inc. Butyl rubber containing allylic alcohol
EP3181595A1 (en) 2015-12-17 2017-06-21 Lanxess Inc. Treatment of epoxidized unsaturated isoolefin copolymers
US20230016289A1 (en) 2019-12-17 2023-01-19 Exxonmobil Chemical Patents Inc. Functionalized Polymers Tread Additive To Improve All-Season Tire Performance

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB774756A (en)
US2356128A (en) 1939-10-20 1944-08-22 Jasco Inc Mixed olefinic polymerization process and product
USRE25007E (en) 1952-01-12 1961-07-04 Us Rubber Co Vulcanization of butyl rubber with para substituted
NL200047A (en) * 1954-09-30
US3165496A (en) 1957-06-12 1965-01-12 Exxon Research Engineering Co Halomethyl hydrocarbon-substituted phenols
US3093613A (en) 1957-06-12 1963-06-11 Exxon Research Engineering Co Vulcanization of synthetic rubber with polyhalomethyl phenol substances
FR1383947A (en) * 1963-11-12 1965-01-04 Aquitaine Petrole Process for epoxidation of unsaturated macromolecular substances and products obtained
FR1527043A (en) 1967-04-10 1968-05-31 Aquitaine Petrole Graft copolymers
US4451589A (en) * 1981-06-15 1984-05-29 Kimberly-Clark Corporation Method of improving processability of polymers and resulting polymer compositions
JP2562648B2 (en) * 1988-03-03 1996-12-11 出光石油化学株式会社 Method for producing hydroxyl group-containing liquid polymer
CA2022349C (en) * 1989-10-13 2001-07-17 Daryl L. Stein Peroxide masterbatches using polycaprolactone as the carrier
KR100227998B1 (en) * 1991-04-29 1999-11-01 오노 알버어스 Cross-linked epoxy functionalized polydiene block polymers, process to prepare them, adhesive compositions and starting block polymers
US5382604A (en) 1991-10-07 1995-01-17 Shell Oil Company Crosslinked epoxy functionalized polydiene block polymers and adhesives
US5242989A (en) 1992-04-03 1993-09-07 Shell Oil Company Hydroxyl functional derivatives of epoxidized diene polymers and process for making them
TW226380B (en) * 1992-04-03 1994-07-11 Shell Internat Res Schappej B V
US5247026A (en) * 1992-06-19 1993-09-21 Shell Oil Company Randomly epoxidized small star polymers
DE19631731A1 (en) 1996-08-06 1998-02-12 Bayer Ag Halogenated butyl rubbers with a low halogen content
CN1128175C (en) 2000-02-16 2003-11-19 太仓市宝马密封材料有限公司 Sealing elastomer material reinforced by non-asbestos fibres and technology for compressing it into plates
CN1121440C (en) * 2000-03-16 2003-09-17 上海交通大学 Process for preparing epoxidized elastomer
CN1113902C (en) 2000-10-26 2003-07-09 上海交通大学 Process for preparing epoxidized elastomer
JP3649676B2 (en) * 2001-05-14 2005-05-18 ダイセル化学工業株式会社 Process for producing epoxidized diene polymer
WO2002092636A1 (en) * 2001-05-14 2002-11-21 Daicel Chemical Industries, Ltd. Process for producing epoxidized diene polymer
JP3649675B2 (en) * 2001-05-14 2005-05-18 ダイセル化学工業株式会社 Process for producing epoxidized diene polymer
DE10163783A1 (en) * 2001-12-22 2003-07-03 Degussa Process for the preparation of epoxidized polyalkenylenes and use of phosphonic acids and their derivatives as catalysts
ATE422520T1 (en) * 2002-07-05 2009-02-15 Exxonmobil Chem Patents Inc NANOCOMPOSIT COMPOSITION CONTAINING FUNCTIONALIZED ELASTOMER
CN100554325C (en) * 2003-10-31 2009-10-28 倍耐力轮胎公司 High-performance wheel tire
US20070276062A1 (en) 2003-12-24 2007-11-29 Diego Tirelli Process For Producing An Epoxidized Elastomeric Polymer
CA2557225A1 (en) 2005-08-26 2007-02-26 Lanxess Inc. Halobutyl elastomers
CA2627338C (en) * 2005-10-27 2011-08-02 Exxonmobil Chemical Patents Inc. Construction comprising tie layer
JP2009173727A (en) 2008-01-23 2009-08-06 Toyota Motor Corp Modified rubber and method for producing it
TWI526461B (en) 2010-08-13 2016-03-21 朗盛公司 Novel graft copolymers and their method of preparation
SG11201504453TA (en) * 2012-12-13 2015-07-30 Lanxess Butyl Pte Ltd Processes for preparing epoxidized polymers
RU2509781C1 (en) * 2012-12-19 2014-03-20 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Башкирский государственный университет" Method of producing epoxidated 1,2-polybutadienes
US9212239B2 (en) 2013-05-30 2015-12-15 The Goodyear Tire & Rubber Company Method of making functionalized elastomer
EP3181595A1 (en) 2015-12-17 2017-06-21 Lanxess Inc. Treatment of epoxidized unsaturated isoolefin copolymers
EP3181598A1 (en) * 2015-12-17 2017-06-21 Lanxess Inc. Butyl rubber containing allylic alcohol

Also Published As

Publication number Publication date
JP2019502797A (en) 2019-01-31
WO2017100922A1 (en) 2017-06-22
JP6873135B2 (en) 2021-05-19
SA518391860B1 (en) 2021-12-14
CN109196001A (en) 2019-01-11
KR20180095033A (en) 2018-08-24
US20190002597A1 (en) 2019-01-03
RU2018126156A3 (en) 2020-04-30
EP3390463B1 (en) 2023-07-26
CA3008290C (en) 2023-10-17
CN113461840A (en) 2021-10-01
US10774158B2 (en) 2020-09-15
CA3008290A1 (en) 2017-06-22
RU2742375C2 (en) 2021-02-05
EP3390463A4 (en) 2019-06-05
EP3390463A1 (en) 2018-10-24
EP3181596A1 (en) 2017-06-21
RU2018126156A (en) 2020-01-20
CN109196001B (en) 2021-10-01

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