SG11201803324VA - Trispecific and/or trivalent binding proteins for prevention or treatment of hiv infection - Google Patents
Trispecific and/or trivalent binding proteins for prevention or treatment of hiv infectionInfo
- Publication number
- SG11201803324VA SG11201803324VA SG11201803324VA SG11201803324VA SG11201803324VA SG 11201803324V A SG11201803324V A SG 11201803324VA SG 11201803324V A SG11201803324V A SG 11201803324VA SG 11201803324V A SG11201803324V A SG 11201803324VA SG 11201803324V A SG11201803324V A SG 11201803324VA
- Authority
- SG
- Singapore
- Prior art keywords
- trispecific
- prevention
- treatment
- binding proteins
- hiv infection
- Prior art date
Links
- 102000014914 Carrier Proteins Human genes 0.000 title 1
- 208000031886 HIV Infections Diseases 0.000 title 1
- 208000037357 HIV infectious disease Diseases 0.000 title 1
- 108091008324 binding proteins Proteins 0.000 title 1
- 208000033519 human immunodeficiency virus infectious disease Diseases 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6881—Cluster-antibody conjugates, i.e. the modifying agent consists of a plurality of antibodies covalently linked to each other or of different antigen-binding fragments covalently linked to each other
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1036—Retroviridae, e.g. leukemia viruses
- C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
- C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- AIDS & HIV (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562246113P | 2015-10-25 | 2015-10-25 | |
EP16305211 | 2016-02-24 | ||
US201662322029P | 2016-04-13 | 2016-04-13 | |
US201662331169P | 2016-05-03 | 2016-05-03 | |
PCT/US2016/058540 WO2017074878A1 (en) | 2015-10-25 | 2016-10-24 | Trispecific and/or trivalent binding proteins for prevention or treatment of hiv infection |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201803324VA true SG11201803324VA (en) | 2018-05-30 |
Family
ID=55588187
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201803324VA SG11201803324VA (en) | 2015-10-25 | 2016-10-24 | Trispecific and/or trivalent binding proteins for prevention or treatment of hiv infection |
Country Status (31)
Country | Link |
---|---|
US (3) | US20190054182A1 (en) |
EP (2) | EP3365366B1 (en) |
JP (3) | JP7169190B2 (en) |
KR (1) | KR20180063336A (en) |
CN (4) | CN116675776A (en) |
AR (1) | AR106466A1 (en) |
AU (2) | AU2016347058B2 (en) |
BR (1) | BR112018008011A2 (en) |
CA (1) | CA3002664A1 (en) |
CL (1) | CL2018001065A1 (en) |
CO (1) | CO2018005337A2 (en) |
CR (1) | CR20180288A (en) |
DO (1) | DOP2018000102A (en) |
EA (1) | EA201891028A1 (en) |
ES (1) | ES2894304T3 (en) |
HK (1) | HK1253385A1 (en) |
HR (1) | HRP20211528T1 (en) |
HU (1) | HUE056608T2 (en) |
IL (2) | IL301140A (en) |
MA (1) | MA42641A1 (en) |
MX (2) | MX2018005048A (en) |
MY (1) | MY192278A (en) |
PE (1) | PE20181167A1 (en) |
PH (1) | PH12018500873A1 (en) |
PL (1) | PL3365366T3 (en) |
RS (1) | RS62437B1 (en) |
SG (1) | SG11201803324VA (en) |
SI (1) | SI3365366T1 (en) |
TW (2) | TW202219064A (en) |
UY (1) | UY36965A (en) |
WO (1) | WO2017074878A1 (en) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10376583B2 (en) | 2013-09-30 | 2019-08-13 | Beth Israel Deaconess Medical Center, Inc. | Human immunodeficiency virus therapies utilizing N332-glycan-dependent antibodies and a reservoir activator |
CN106459186B (en) * | 2014-02-28 | 2021-02-02 | 美国卫生和人力服务部 | Broadly neutralizing monoclonal antibodies against the ENV region of HIV-1V 2 |
BR112018008011A2 (en) * | 2015-10-25 | 2018-10-30 | Sanofi | trypecific and / or trivalent binding proteins for prevention or treatment of HIV infection |
US11236152B2 (en) * | 2015-11-03 | 2022-02-01 | The United States of America, as represented by the Sectetary, Department of Health and Human Services | Neutralizing antibodies to HIV-1 GP41 and their use |
EP3443006B1 (en) | 2016-04-13 | 2023-08-02 | Sanofi | Trispecific and/or trivalent binding proteins |
RS64771B1 (en) | 2016-04-13 | 2023-11-30 | Sanofi Sa | Trispecific and/or trivalent binding proteins |
EP3448987A4 (en) | 2016-04-29 | 2020-05-27 | Voyager Therapeutics, Inc. | Compositions for the treatment of disease |
WO2017189959A1 (en) | 2016-04-29 | 2017-11-02 | Voyager Therapeutics, Inc. | Compositions for the treatment of disease |
US10626169B2 (en) | 2017-02-17 | 2020-04-21 | Sanofi | Multispecific binding molecules having specificity to dystroglycan and laminin-2 |
CA3053774A1 (en) | 2017-02-17 | 2018-08-23 | Sanofi | Multispecific binding molecules having specificity to dystroglycan and laminin-2 |
EP3642229A1 (en) * | 2017-06-21 | 2020-04-29 | Gilead Sciences, Inc. | Multispecific antibodies that target hiv gp120 and cd3 |
CN117964758A (en) | 2017-10-10 | 2024-05-03 | 赛诺菲 | Anti-CD 38 antibodies and combinations with anti-CD 3 and anti-CD 28 antibodies |
CN111819196B (en) * | 2017-12-21 | 2022-10-28 | 纽约市哥伦比亚大学理事会 | Bispecific HIV-1 neutralizing antibodies |
US11067584B2 (en) | 2018-01-12 | 2021-07-20 | Genzyme Corporation | Methods for the quantitation of polypeptides |
WO2019226829A1 (en) | 2018-05-22 | 2019-11-28 | Beth Israel Deaconess Medical Center, Inc. | Antibody therapies for human immunodeficiency virus (hiv) |
BR112021006558A2 (en) * | 2018-10-09 | 2021-07-13 | Sanofi | anti-cd38, anti-cd28 and anti-cd3 trispecific binding proteins and methods of use for the treatment of viral infection |
WO2020106713A1 (en) * | 2018-11-21 | 2020-05-28 | Beth Israel Deaconess Medical Center, Inc. | Antibody therapies for human immunodeficiency virus (hiv) |
TW202104274A (en) | 2019-04-09 | 2021-02-01 | 法商賽諾菲公司 | Trispecific and/or trivalent binding proteins for treatment of hiv infection |
US11613576B2 (en) | 2019-04-09 | 2023-03-28 | Sanofi | Trispecific binding proteins, methods, and uses thereof |
WO2020210392A1 (en) | 2019-04-09 | 2020-10-15 | Sanofi | Trispecific binding proteins, methods, and uses thereof |
IL292480A (en) | 2019-10-25 | 2022-06-01 | Sanofi Sa | Methods for analyzing chain mispairing in multispecific binding proteins |
US20230203466A1 (en) * | 2020-04-03 | 2023-06-29 | Medgenome Inc. | Ace2 receptor polymorphisms and varying susceptibility to sars-cov-2, methods for diagnosis and treatment |
CN116157416A (en) * | 2020-08-25 | 2023-05-23 | 吉利德科学公司 | HIV-targeting multispecific antigen-binding molecules and methods of use thereof |
CN118251411A (en) * | 2021-09-29 | 2024-06-25 | 摩德斯医疗股份有限公司 | Antigen binding polypeptides, antigen binding polypeptide complexes, and methods of use thereof |
Family Cites Families (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE108068T1 (en) | 1987-09-23 | 1994-07-15 | Bristol Myers Squibb Co | ANTIBODY HETEROCONJUGATES FOR KILLING HIV-INFECTED CELLS. |
US5731168A (en) | 1995-03-01 | 1998-03-24 | Genentech, Inc. | Method for making heteromultimeric polypeptides |
JP2002510481A (en) | 1998-04-02 | 2002-04-09 | ジェネンテック・インコーポレーテッド | Antibody variants and fragments thereof |
CA2433877C (en) | 2001-01-17 | 2014-11-18 | Genecraft, Inc. | Binding domain-immunoglobulin fusion proteins |
CN1294148C (en) | 2001-04-11 | 2007-01-10 | 中国科学院遗传与发育生物学研究所 | Single-stranded cyctic trispecific antibody |
US20050163782A1 (en) | 2003-06-27 | 2005-07-28 | Biogen Idec Ma Inc. | Modified binding molecules comprising connecting peptides |
US9200061B2 (en) | 2004-02-06 | 2015-12-01 | Morpho Sys AG | Generation and profiling of fully human HuCAL gold®-derived therapeutic antibodies specific for human CD3i |
CN100376599C (en) | 2004-04-01 | 2008-03-26 | 北京安波特基因工程技术有限公司 | Recombining single chained three specific antibodies of anti CCA, anti CD 3, anti CD 28 through genetic engineering |
EP2014680A1 (en) * | 2007-07-10 | 2009-01-14 | Friedrich-Alexander-Universität Erlangen-Nürnberg | Recombinant, single-chain, trivalent tri-specific or bi-specific antibody derivatives |
EP2050764A1 (en) | 2007-10-15 | 2009-04-22 | sanofi-aventis | Novel polyvalent bispecific antibody format and uses thereof |
PE20100092A1 (en) | 2008-06-03 | 2010-03-12 | Abbott Lab | IMMUNOGLOBULIN WITH DUAL VARIABLE DOMAIN AND USES OF THE SAME |
AU2010298025B2 (en) | 2009-09-25 | 2016-04-21 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Neutralizing antibodies to HIV-1 and their use |
WO2011154453A1 (en) | 2010-06-09 | 2011-12-15 | Genmab A/S | Antibodies against human cd38 |
CN103282385A (en) | 2010-11-12 | 2013-09-04 | 美国洛克菲勒大学 | Fusion proteins for HIV therapy |
JOP20210044A1 (en) | 2010-12-30 | 2017-06-16 | Takeda Pharmaceuticals Co | Anti-cd38 antibodies |
TWI588156B (en) | 2011-03-28 | 2017-06-21 | 賽諾菲公司 | Dual variable region antibody-like binding proteins having cross-over binding region orientation |
WO2012154312A1 (en) | 2011-05-09 | 2012-11-15 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Neutralizing antibodies to hiv-1 and their use |
CN103842383B (en) | 2011-05-16 | 2017-11-03 | 健能隆医药技术(上海)有限公司 | Polyspecific FAB fusion proteins and its application method |
CN103797029B (en) * | 2011-05-17 | 2016-08-17 | 洛克菲勒大学 | Human immunodeficiency virus neutralizing antibody and using method thereof |
RU2624046C2 (en) | 2011-11-07 | 2017-06-30 | Дзе Юнайтед Стейтс Оф Америка, Эз Репрезентед Бай Дзе Секретэри, Департмент Оф Хелт Энд Хьюман Сервисиз | gp41-NEUTRALIZING ANTIBODIES AND THEIR APPLICATION |
WO2013070565A1 (en) * | 2011-11-07 | 2013-05-16 | Medimmune, Llc | Multispecific and multivalent binding proteins and uses thereof |
AU2012347453B2 (en) | 2011-12-08 | 2017-11-23 | The United States Of America, As Represented By The Secretary Department Of Health And Human Services | Neutralizing antibodies to HIV-1 and their use |
WO2013163427A1 (en) * | 2012-04-25 | 2013-10-31 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Antibodies to treat hiv-1 infection |
JOP20200236A1 (en) | 2012-09-21 | 2017-06-16 | Regeneron Pharma | Anti-cd3 antibodies, bispecific antigen-binding molecules that bind cd3 and cd20, and uses thereof |
IN2015MN00139A (en) * | 2012-09-25 | 2015-10-16 | Glenmark Pharmaceuticals Sa | |
US9951106B2 (en) | 2012-12-04 | 2018-04-24 | University Of Maryland, Baltimore | Recombinant fusion protein comprising HIV gp120 linked to an enhancing CD4 binding site mAb |
MX2015007575A (en) | 2012-12-13 | 2016-03-15 | Univ Pennsylvania | Dna antibody constructs and method of using same. |
US20140213772A1 (en) | 2012-12-28 | 2014-07-31 | Abbvie, Inc. | Cross-over dual variable domain immunoglobulin constructs |
US10487155B2 (en) | 2013-01-14 | 2019-11-26 | Xencor, Inc. | Heterodimeric proteins |
US20140242077A1 (en) | 2013-01-23 | 2014-08-28 | Abbvie, Inc. | Methods and compositions for modulating an immune response |
MY192312A (en) | 2013-02-26 | 2022-08-17 | Roche Glycart Ag | Bispecific t cell activating antigen binding molecules |
US20140302037A1 (en) | 2013-03-15 | 2014-10-09 | Amgen Inc. | BISPECIFIC-Fc MOLECULES |
EP2970457A2 (en) | 2013-03-15 | 2016-01-20 | AbbVie Inc. | Dual specific binding proteins directed against tnf |
EP3027755B1 (en) | 2013-08-02 | 2019-10-09 | The Regents of The University of California | Engineering antiviral t cell immunity through stem cells and chimeric antigen receptors |
SG11201603244VA (en) | 2013-11-04 | 2016-05-30 | Glenmark Pharmaceuticals Sa | Production of t cell retargeting hetero-dimeric immunoglobulins |
ME03666B (en) | 2014-03-28 | 2020-10-20 | Xencor Inc | Bispecific antibodies that bind to cd38 and cd3 |
CN106687584B (en) | 2014-09-04 | 2021-08-13 | 干细胞技术公司 | Soluble antibody complexes for T cell or NK cell activation and expansion |
CN107428835B (en) | 2015-01-23 | 2021-11-26 | 赛诺菲 | anti-CD 3 antibodies, anti-CD 123 antibodies, and bispecific antibodies that specifically bind to CD3 and/or CD123 |
MX2017014821A (en) | 2015-05-20 | 2018-06-27 | Quantum Si Inc | Method of determining the sequence of a nuclear acid using time resolved luminescence. |
US10654943B2 (en) | 2015-06-02 | 2020-05-19 | The Rockefeller University | Tri-specific antibodies for HIV therapy |
JP6991131B2 (en) | 2015-09-22 | 2022-02-03 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | How to reorient T cells to treat HIV infection |
BR112018008011A2 (en) | 2015-10-25 | 2018-10-30 | Sanofi | trypecific and / or trivalent binding proteins for prevention or treatment of HIV infection |
CN105837688B (en) | 2015-11-20 | 2019-02-26 | 北京大学深圳研究生院 | Single domain antibody and its encoding gene, immunotoxin and its encoding gene, preparation method, expression vector, application and host cell |
AR106991A1 (en) | 2015-12-15 | 2018-03-07 | Gilead Sciences Inc | NEUTRALIZING ANTIBODIES OF THE HUMAN IMMUNODEFICIENCY VIRUS |
RS64771B1 (en) | 2016-04-13 | 2023-11-30 | Sanofi Sa | Trispecific and/or trivalent binding proteins |
EP3443006B1 (en) | 2016-04-13 | 2023-08-02 | Sanofi | Trispecific and/or trivalent binding proteins |
US20230242876A1 (en) | 2016-12-30 | 2023-08-03 | Shanghai Sinobio Biotech Co., Ltd. | Bifunctional molecule and use thereof |
CA3053774A1 (en) | 2017-02-17 | 2018-08-23 | Sanofi | Multispecific binding molecules having specificity to dystroglycan and laminin-2 |
US10626169B2 (en) | 2017-02-17 | 2020-04-21 | Sanofi | Multispecific binding molecules having specificity to dystroglycan and laminin-2 |
EP3601334A4 (en) | 2017-03-27 | 2021-03-31 | The Wistar Institute Of Anatomy And Biology | Dna antibody constructs for use against hiv |
CN117964758A (en) | 2017-10-10 | 2024-05-03 | 赛诺菲 | Anti-CD 38 antibodies and combinations with anti-CD 3 and anti-CD 28 antibodies |
BR112021006558A2 (en) | 2018-10-09 | 2021-07-13 | Sanofi | anti-cd38, anti-cd28 and anti-cd3 trispecific binding proteins and methods of use for the treatment of viral infection |
US11613576B2 (en) | 2019-04-09 | 2023-03-28 | Sanofi | Trispecific binding proteins, methods, and uses thereof |
-
2016
- 2016-10-24 BR BR112018008011A patent/BR112018008011A2/en active Search and Examination
- 2016-10-24 WO PCT/US2016/058540 patent/WO2017074878A1/en active Application Filing
- 2016-10-24 EA EA201891028A patent/EA201891028A1/en unknown
- 2016-10-24 PE PE2018000603A patent/PE20181167A1/en unknown
- 2016-10-24 IL IL301140A patent/IL301140A/en unknown
- 2016-10-24 CN CN202310147287.XA patent/CN116675776A/en active Pending
- 2016-10-24 CA CA3002664A patent/CA3002664A1/en active Pending
- 2016-10-24 US US15/770,471 patent/US20190054182A1/en not_active Abandoned
- 2016-10-24 CN CN202310185803.8A patent/CN117069855A/en active Pending
- 2016-10-24 HU HUE16794472A patent/HUE056608T2/en unknown
- 2016-10-24 MA MA42641A patent/MA42641A1/en unknown
- 2016-10-24 AU AU2016347058A patent/AU2016347058B2/en active Active
- 2016-10-24 EP EP16794472.7A patent/EP3365366B1/en active Active
- 2016-10-24 KR KR1020187014534A patent/KR20180063336A/en active IP Right Grant
- 2016-10-24 RS RS20211266A patent/RS62437B1/en unknown
- 2016-10-24 CR CR20180288A patent/CR20180288A/en unknown
- 2016-10-24 HR HRP20211528TT patent/HRP20211528T1/en unknown
- 2016-10-24 JP JP2018521308A patent/JP7169190B2/en active Active
- 2016-10-24 PL PL16794472T patent/PL3365366T3/en unknown
- 2016-10-24 MY MYPI2018701634A patent/MY192278A/en unknown
- 2016-10-24 MX MX2018005048A patent/MX2018005048A/en unknown
- 2016-10-24 ES ES16794472T patent/ES2894304T3/en active Active
- 2016-10-24 EP EP20197556.2A patent/EP3819310A1/en active Pending
- 2016-10-24 SI SI201631358T patent/SI3365366T1/en unknown
- 2016-10-24 CN CN202310186776.6A patent/CN116789841A/en active Pending
- 2016-10-24 CN CN201680075852.4A patent/CN109311966B/en active Active
- 2016-10-24 SG SG11201803324VA patent/SG11201803324VA/en unknown
- 2016-10-25 UY UY0001036965A patent/UY36965A/en not_active Application Discontinuation
- 2016-10-25 TW TW110126977A patent/TW202219064A/en unknown
- 2016-10-25 AR ARP160103249A patent/AR106466A1/en unknown
- 2016-10-25 TW TW105134405A patent/TWI750139B/en active
-
2018
- 2018-04-20 DO DO2018000102A patent/DOP2018000102A/en unknown
- 2018-04-22 IL IL258822A patent/IL258822B2/en unknown
- 2018-04-23 CL CL2018001065A patent/CL2018001065A1/en unknown
- 2018-04-23 PH PH12018500873A patent/PH12018500873A1/en unknown
- 2018-04-24 MX MX2022014631A patent/MX2022014631A/en unknown
- 2018-05-22 CO CONC2018/0005337A patent/CO2018005337A2/en unknown
- 2018-10-04 HK HK18112682.8A patent/HK1253385A1/en unknown
-
2019
- 2019-10-21 US US16/659,426 patent/US11129905B2/en active Active
-
2021
- 2021-02-04 JP JP2021016190A patent/JP7328267B2/en active Active
- 2021-08-17 US US17/404,908 patent/US11779651B2/en active Active
-
2023
- 2023-04-06 JP JP2023061823A patent/JP2023085476A/en active Pending
-
2024
- 2024-01-22 AU AU2024200395A patent/AU2024200395A1/en active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1253385A1 (en) | Trispecific and/or trivalent binding proteins for prevention or treatment of hiv infection | |
IL262241A (en) | Trispecific and/or trivalent binding proteins | |
HK1253882A1 (en) | Methods and compositions for rna-guided treatment of hiv infection | |
HK1251554A1 (en) | Novel substituted aminothiazolopyrimidinedione for the treatment and prophylaxis of virus infection | |
HK1248711A1 (en) | Novel substituted aminothiazolopyrimidinedione for the treatment and prophylaxis of virus infection | |
IL253243A0 (en) | Combined preparations for the treatment of cancer or infection | |
ZA201705634B (en) | Quinoline derivatives for use in the treatment or prevention of viral infection | |
HK1258276A1 (en) | Compounds and combinations for the treatment of hiv | |
HK1250480A1 (en) | Compositions and methods for the treatment of hbv infection | |
IL263368A (en) | Prevention and treatment of viral infections | |
HK1252343A1 (en) | Compositions and methods for the treatment of viral infection | |
ZA202006103B (en) | Trispecific and/or trivalent binding proteins | |
PL3183003T3 (en) | Methods for prevention and/or treatment of infection | |
GB201615035D0 (en) | Treatment and prevention of viral infection | |
SG10202003467RA (en) | Trispecific and/or trivalent binding proteins for prevention or treatment of hiv infection | |
PT3365366T (en) | Trispecific and/or trivalent binding proteins for prevention or treatment of hiv infection | |
ZA201806629B (en) | Trispecific and/or trivalent binding proteins | |
GB201519483D0 (en) | Prevention and treatment of microbial infections | |
GB201518252D0 (en) | Prevention and treatment of microbial infections | |
GB201513047D0 (en) | Prevention and treatment of microbial infections | |
GB201511576D0 (en) | Prevention and treatment of microbial infections | |
GB201509654D0 (en) | Prevention and treatment of microbial infections | |
GB201508313D0 (en) | Prevention and treatment of microbial infections |