HK1251554A1 - Novel substituted aminothiazolopyrimidinedione for the treatment and prophylaxis of virus infection - Google Patents

Novel substituted aminothiazolopyrimidinedione for the treatment and prophylaxis of virus infection

Info

Publication number
HK1251554A1
HK1251554A1 HK18110891.9A HK18110891A HK1251554A1 HK 1251554 A1 HK1251554 A1 HK 1251554A1 HK 18110891 A HK18110891 A HK 18110891A HK 1251554 A1 HK1251554 A1 HK 1251554A1
Authority
HK
Hong Kong
Prior art keywords
aminothiazolopyrimidinedione
prophylaxis
treatment
virus infection
novel substituted
Prior art date
Application number
HK18110891.9A
Other languages
Chinese (zh)
Inventor
Lisha Wang
Hongying Yun
Xiufang Zheng
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1251554A1 publication Critical patent/HK1251554A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/24—Heterocyclic radicals containing oxygen or sulfur as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
HK18110891.9A 2015-06-30 2018-08-23 Novel substituted aminothiazolopyrimidinedione for the treatment and prophylaxis of virus infection HK1251554A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2015082844 2015-06-30
PCT/EP2016/064771 WO2017001307A1 (en) 2015-06-30 2016-06-27 Novel substituted aminothiazolopyrimidinedione for the treatment and prophylaxis of virus infection

Publications (1)

Publication Number Publication Date
HK1251554A1 true HK1251554A1 (en) 2019-02-01

Family

ID=56235829

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18110891.9A HK1251554A1 (en) 2015-06-30 2018-08-23 Novel substituted aminothiazolopyrimidinedione for the treatment and prophylaxis of virus infection

Country Status (6)

Country Link
US (2) US10590146B2 (en)
EP (1) EP3317289B1 (en)
JP (1) JP6839104B2 (en)
CN (1) CN107820498B (en)
HK (1) HK1251554A1 (en)
WO (1) WO2017001307A1 (en)

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CN113543851A (en) 2019-03-07 2021-10-22 捷克共和国有机化学与生物化学研究所 2'3' -cyclic dinucleotides and their prodrugs
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WO2020237025A1 (en) 2019-05-23 2020-11-26 Gilead Sciences, Inc. Substituted exo-methylene-oxindoles which are hpk1/map4k1 inhibitors
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Also Published As

Publication number Publication date
US10590146B2 (en) 2020-03-17
EP3317289B1 (en) 2021-10-27
US10975098B2 (en) 2021-04-13
CN107820498A (en) 2018-03-20
JP6839104B2 (en) 2021-03-03
WO2017001307A1 (en) 2017-01-05
CN107820498B (en) 2020-06-19
EP3317289A1 (en) 2018-05-09
JP2018527309A (en) 2018-09-20
US20180118763A1 (en) 2018-05-03
US20200231600A1 (en) 2020-07-23

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