SG11201802905TA - Novel process for preparing thienopyrimidine compound and intermediates used therein - Google Patents

Novel process for preparing thienopyrimidine compound and intermediates used therein

Info

Publication number
SG11201802905TA
SG11201802905TA SG11201802905TA SG11201802905TA SG11201802905TA SG 11201802905T A SG11201802905T A SG 11201802905TA SG 11201802905T A SG11201802905T A SG 11201802905TA SG 11201802905T A SG11201802905T A SG 11201802905TA SG 11201802905T A SG11201802905T A SG 11201802905TA
Authority
SG
Singapore
Prior art keywords
novel process
intermediates used
thienopyrimidine compound
preparing
preparing thienopyrimidine
Prior art date
Application number
SG11201802905TA
Inventor
Wook Jang
Young Ho Moon
Tae Hee Ha
Kwee Hyun Suh
Original Assignee
Hanmi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hanmi Pharmaceutical Co Ltd filed Critical Hanmi Pharmaceutical Co Ltd
Publication of SG11201802905TA publication Critical patent/SG11201802905TA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965Non-condensed pyrazines
    • A61K31/497Non-condensed pyrazines containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG11201802905TA 2015-10-30 2016-10-31 Novel process for preparing thienopyrimidine compound and intermediates used therein SG11201802905TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020150151993A KR20170050453A (en) 2015-10-30 2015-10-30 Novel process for preparing thienopyrimidine compound and intermediates used therein
PCT/KR2016/012335 WO2017074147A1 (en) 2015-10-30 2016-10-31 Novel process for preparing thienopyrimidine compound and intermediates used therein

Publications (1)

Publication Number Publication Date
SG11201802905TA true SG11201802905TA (en) 2018-05-30

Family

ID=58630691

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201802905TA SG11201802905TA (en) 2015-10-30 2016-10-31 Novel process for preparing thienopyrimidine compound and intermediates used therein

Country Status (11)

Country Link
US (1) US10392403B2 (en)
EP (1) EP3356372B1 (en)
JP (1) JP2018531952A (en)
KR (1) KR20170050453A (en)
CN (1) CN108349992A (en)
AU (1) AU2016345967A1 (en)
HK (1) HK1251228A1 (en)
IL (1) IL258639A (en)
SG (1) SG11201802905TA (en)
TW (1) TW201722963A (en)
WO (1) WO2017074147A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201726686A (en) * 2015-12-31 2017-08-01 韓美藥品股份有限公司 Crystalline forms of thienopyrimidine compound

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6245759B1 (en) 1999-03-11 2001-06-12 Merck & Co., Inc. Tyrosine kinase inhibitors
US8822500B2 (en) * 2008-03-19 2014-09-02 Chembridge Corporation Tyrosine kinase inhibitors
LT2975042T (en) * 2010-06-23 2019-01-25 Hanmi Science Co., Ltd. Novel fused pyrimidine derivatives for inhibition of tyrosine kinase activity
KR20140118575A (en) 2013-03-29 2014-10-08 한미약품 주식회사 Novel hydroxamate derivative
CN105916851A (en) * 2013-07-11 2016-08-31 艾森生物科学公司 Heterocyclic compounds and uses thereof
US10040801B2 (en) * 2014-12-30 2018-08-07 Hanmi Pharm. Co., Ltd. Method for preparing thienopyrimidine compound and intermediates used therein
CN108137614B (en) * 2015-12-02 2021-01-05 深圳市塔吉瑞生物医药有限公司 Fused pyrimidine compound, composition containing compound and application of compound
TW201726686A (en) * 2015-12-31 2017-08-01 韓美藥品股份有限公司 Crystalline forms of thienopyrimidine compound

Also Published As

Publication number Publication date
CN108349992A (en) 2018-07-31
HK1251228A1 (en) 2019-01-25
EP3356372A4 (en) 2019-03-27
WO2017074147A1 (en) 2017-05-04
EP3356372A1 (en) 2018-08-08
KR20170050453A (en) 2017-05-11
JP2018531952A (en) 2018-11-01
US20180312520A1 (en) 2018-11-01
TW201722963A (en) 2017-07-01
US10392403B2 (en) 2019-08-27
AU2016345967A1 (en) 2018-04-26
EP3356372B1 (en) 2020-08-05
IL258639A (en) 2018-06-28

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