SG11201802905TA - Novel process for preparing thienopyrimidine compound and intermediates used therein - Google Patents
Novel process for preparing thienopyrimidine compound and intermediates used thereinInfo
- Publication number
- SG11201802905TA SG11201802905TA SG11201802905TA SG11201802905TA SG11201802905TA SG 11201802905T A SG11201802905T A SG 11201802905TA SG 11201802905T A SG11201802905T A SG 11201802905TA SG 11201802905T A SG11201802905T A SG 11201802905TA SG 11201802905T A SG11201802905T A SG 11201802905TA
- Authority
- SG
- Singapore
- Prior art keywords
- novel process
- intermediates used
- thienopyrimidine compound
- preparing
- preparing thienopyrimidine
- Prior art date
Links
- 239000000543 intermediate Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- -1 thienopyrimidine compound Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020150151993A KR20170050453A (en) | 2015-10-30 | 2015-10-30 | Novel process for preparing thienopyrimidine compound and intermediates used therein |
| PCT/KR2016/012335 WO2017074147A1 (en) | 2015-10-30 | 2016-10-31 | Novel process for preparing thienopyrimidine compound and intermediates used therein |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201802905TA true SG11201802905TA (en) | 2018-05-30 |
Family
ID=58630691
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201802905TA SG11201802905TA (en) | 2015-10-30 | 2016-10-31 | Novel process for preparing thienopyrimidine compound and intermediates used therein |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US10392403B2 (en) |
| EP (1) | EP3356372B1 (en) |
| JP (1) | JP2018531952A (en) |
| KR (1) | KR20170050453A (en) |
| CN (1) | CN108349992A (en) |
| AU (1) | AU2016345967A1 (en) |
| HK (1) | HK1251228A1 (en) |
| IL (1) | IL258639A (en) |
| SG (1) | SG11201802905TA (en) |
| TW (1) | TW201722963A (en) |
| WO (1) | WO2017074147A1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017116193A1 (en) | 2015-12-31 | 2017-07-06 | Hanmi Pharm. Co., Ltd. | Crystalline forms of thienopyrimidine compound |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6245759B1 (en) * | 1999-03-11 | 2001-06-12 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
| BR112012033253A2 (en) * | 2010-06-23 | 2016-11-22 | Hanmi Science Co Ltd | novel fused pyrimidine derivatives for inhibition of tyrosine kinase activity |
| WO2012037155A2 (en) * | 2010-09-13 | 2012-03-22 | Gtx, Inc. | Tyrosine kinase inhibitors |
| KR20140118575A (en) | 2013-03-29 | 2014-10-08 | 한미약품 주식회사 | Novel hydroxamate derivative |
| CN117486865A (en) * | 2013-07-11 | 2024-02-02 | 艾森医药公司 | Pyrimidine derivatives as kinase inhibitors |
| CN107108649B (en) * | 2014-12-30 | 2019-08-09 | 韩美药品株式会社 | Be used to prepare Thienopyrimidine compound novel method and its used in intermediate |
| WO2017092523A1 (en) * | 2015-12-02 | 2017-06-08 | 深圳市塔吉瑞生物医药有限公司 | Fused pyrimidine compound, composition comprising same and use of same |
| WO2017116193A1 (en) * | 2015-12-31 | 2017-07-06 | Hanmi Pharm. Co., Ltd. | Crystalline forms of thienopyrimidine compound |
-
2015
- 2015-10-30 KR KR1020150151993A patent/KR20170050453A/en unknown
-
2016
- 2016-10-31 TW TW105135265A patent/TW201722963A/en unknown
- 2016-10-31 AU AU2016345967A patent/AU2016345967A1/en not_active Abandoned
- 2016-10-31 EP EP16860330.6A patent/EP3356372B1/en active Active
- 2016-10-31 SG SG11201802905TA patent/SG11201802905TA/en unknown
- 2016-10-31 JP JP2018521115A patent/JP2018531952A/en active Pending
- 2016-10-31 CN CN201680062713.8A patent/CN108349992A/en active Pending
- 2016-10-31 WO PCT/KR2016/012335 patent/WO2017074147A1/en active Application Filing
- 2016-10-31 US US15/770,794 patent/US10392403B2/en not_active Expired - Fee Related
-
2018
- 2018-04-11 IL IL258639A patent/IL258639A/en unknown
- 2018-08-17 HK HK18110610.9A patent/HK1251228A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20180312520A1 (en) | 2018-11-01 |
| AU2016345967A1 (en) | 2018-04-26 |
| EP3356372B1 (en) | 2020-08-05 |
| HK1251228A1 (en) | 2019-01-25 |
| WO2017074147A1 (en) | 2017-05-04 |
| CN108349992A (en) | 2018-07-31 |
| JP2018531952A (en) | 2018-11-01 |
| EP3356372A4 (en) | 2019-03-27 |
| KR20170050453A (en) | 2017-05-11 |
| IL258639A (en) | 2018-06-28 |
| EP3356372A1 (en) | 2018-08-08 |
| US10392403B2 (en) | 2019-08-27 |
| TW201722963A (en) | 2017-07-01 |
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