SG11201710695XA - 1,4-disubstituted imidazole derivative - Google Patents

1,4-disubstituted imidazole derivative

Info

Publication number
SG11201710695XA
SG11201710695XA SG11201710695XA SG11201710695XA SG11201710695XA SG 11201710695X A SG11201710695X A SG 11201710695XA SG 11201710695X A SG11201710695X A SG 11201710695XA SG 11201710695X A SG11201710695X A SG 11201710695XA SG 11201710695X A SG11201710695X A SG 11201710695XA
Authority
SG
Singapore
Prior art keywords
imidazole derivative
disubstituted imidazole
disubstituted
derivative
imidazole
Prior art date
Application number
SG11201710695XA
Inventor
Hitoshi Ban
Manabu Kusagi
Shingo Tojo
Futoshi Hasegawa
Miki Hashizume
Original Assignee
Sumitomo Dainippon Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Dainippon Pharma Co Ltd filed Critical Sumitomo Dainippon Pharma Co Ltd
Publication of SG11201710695XA publication Critical patent/SG11201710695XA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/88Carboxylic acid amides having nitrogen atoms of carboxamide groups bound to an acyclic carbon atom and to a carbon atom of a six-membered aromatic ring wherein at least one ortho-hydrogen atom has been replaced
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/422Oxazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
SG11201710695XA 2015-06-22 2016-06-21 1,4-disubstituted imidazole derivative SG11201710695XA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2015125174 2015-06-22
JP2015244856 2015-12-16
PCT/JP2016/068423 WO2016208591A1 (en) 2015-06-22 2016-06-21 1,4-di-substituted imidazole derivative

Publications (1)

Publication Number Publication Date
SG11201710695XA true SG11201710695XA (en) 2018-01-30

Family

ID=57584875

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201710695XA SG11201710695XA (en) 2015-06-22 2016-06-21 1,4-disubstituted imidazole derivative

Country Status (13)

Country Link
US (3) US10807945B2 (en)
EP (1) EP3312170A4 (en)
JP (1) JP6692354B2 (en)
KR (1) KR20180028456A (en)
CN (1) CN107922386B (en)
AU (1) AU2016284398C1 (en)
CA (1) CA2990583A1 (en)
HK (1) HK1248226A1 (en)
PH (1) PH12017502388A1 (en)
RU (1) RU2741000C2 (en)
SG (1) SG11201710695XA (en)
TW (1) TW201713642A (en)
WO (1) WO2016208591A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3323809A4 (en) 2015-06-22 2019-01-02 Sumitomo Dainippon Pharma Co., Ltd. Bicyclic heterocyclic amide derivative
EP3312170A4 (en) 2015-06-22 2018-12-12 Sumitomo Dainippon Pharma Co., Ltd. 1,4-di-substituted imidazole derivative
US10898469B2 (en) 2016-02-26 2021-01-26 Sumitomo Dainippon Pharma Co., Ltd. Imidazolylamide derivative
JPWO2018117196A1 (en) * 2016-12-20 2019-10-31 大日本住友製薬株式会社 Drugs targeting cancer stem cells
JP6775483B2 (en) * 2016-12-20 2020-10-28 大日本住友製薬株式会社 Pharmaceuticals consisting of 1,4-di-substituted imidazole derivatives
WO2018117127A1 (en) * 2016-12-20 2018-06-28 大日本住友製薬株式会社 Agent for removing undifferentiated ips cells
AU2019239481B2 (en) * 2018-03-20 2022-11-24 Sumitomo Pharma Co., Ltd. Dihydrochromene derivative
JP7287929B2 (en) 2019-09-25 2023-06-06 住友ファーマ株式会社 Medicine containing dihydrochromene derivative

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4140788A (en) * 1976-11-10 1979-02-20 Sumitomo Chemical Company, Limited N-Substituted imidazolecarboxamide derivatives
JPS5359664A (en) * 1976-11-10 1978-05-29 Sumitomo Chem Co Ltd Novel imidazole derivatives
EP0858457A1 (en) * 1995-10-20 1998-08-19 Dr. Karl Thomae GmbH 5-membered heterocycles, pharmaceutical agents containing said compounds and the use thereof and methods of producing them
WO1999003858A1 (en) 1997-07-15 1999-01-28 Japan Energy Corporation Novel purine derivatives and medicinal use thereof
CA2560580C (en) * 2004-03-23 2008-12-23 Pfizer Products Inc. Imidazole compounds for inhibition of a.beta.-peptide production and for modulation of the notch signaling pathway
SE0401653D0 (en) 2004-06-24 2004-06-24 Astrazeneca Ab New compounds
AR052666A1 (en) * 2005-02-16 2007-03-28 Solvay Pharm Bv DERIVATIVES OF 1H-IMIDAZOL AS MODULATORS OF THE CANNABINOID CB2 RECEIVER
RU2410377C2 (en) * 2005-02-16 2011-01-27 Солвей Фармасьютикалс Б.В. 1 h-imidazole derivatives as modulators of cannabinoid cb2 receptors
DE102005008183A1 (en) 2005-02-23 2006-08-31 Bayer Healthcare Ag New heterocyclylamide-substituted imidazole compounds useful to treat or prevent viral infections
GB0508472D0 (en) * 2005-04-26 2005-06-01 Glaxo Group Ltd Compounds
AU2006327316A1 (en) 2005-12-23 2007-06-28 Astrazeneca Ab Imidazoles as GABA-B receptor modulators
WO2008073461A2 (en) 2006-12-11 2008-06-19 Wyeth Ion channel modulators
GB0722075D0 (en) * 2007-11-09 2007-12-19 Smithkline Beecham Corp Compounds
ES2588999T3 (en) * 2011-03-22 2016-11-08 Bayer Intellectual Property Gmbh N- (1,3,4-oxadiazol-2-yl) arylcarboxylic acid amides and their use as herbicides
IN2014CN02949A (en) * 2011-10-18 2015-07-03 Astellas Pharma Inc
US20170015677A1 (en) * 2014-03-31 2017-01-19 Boston Biomedical, Inc. New tricyclic quinone derivative
GB201416754D0 (en) * 2014-09-23 2014-11-05 Mission Therapeutics Ltd Novel compounds
EP3312170A4 (en) * 2015-06-22 2018-12-12 Sumitomo Dainippon Pharma Co., Ltd. 1,4-di-substituted imidazole derivative

Also Published As

Publication number Publication date
PH12017502388A1 (en) 2018-07-09
CA2990583A1 (en) 2016-12-29
US20170166552A1 (en) 2017-06-15
TW201713642A (en) 2017-04-16
EP3312170A1 (en) 2018-04-25
JPWO2016208591A1 (en) 2018-04-05
HK1248226A1 (en) 2018-10-12
US20210171440A1 (en) 2021-06-10
AU2016284398B2 (en) 2020-08-06
US9828362B2 (en) 2017-11-28
AU2016284398C1 (en) 2021-01-07
CN107922386A (en) 2018-04-17
RU2018102087A3 (en) 2019-12-25
US10807945B2 (en) 2020-10-20
KR20180028456A (en) 2018-03-16
JP6692354B2 (en) 2020-05-13
RU2741000C2 (en) 2021-01-22
AU2016284398A1 (en) 2018-02-01
US11661397B2 (en) 2023-05-30
WO2016208591A1 (en) 2016-12-29
RU2018102087A (en) 2019-07-23
CN107922386B (en) 2021-04-02
US20180230085A1 (en) 2018-08-16
EP3312170A4 (en) 2018-12-12

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