SG11201709573YA - Specific modification of antibody with igg-binding peptide - Google Patents

Specific modification of antibody with igg-binding peptide

Info

Publication number
SG11201709573YA
SG11201709573YA SG11201709573YA SG11201709573YA SG11201709573YA SG 11201709573Y A SG11201709573Y A SG 11201709573YA SG 11201709573Y A SG11201709573Y A SG 11201709573YA SG 11201709573Y A SG11201709573Y A SG 11201709573YA SG 11201709573Y A SG11201709573Y A SG 11201709573YA
Authority
SG
Singapore
Prior art keywords
igg
antibody
binding peptide
specific modification
modification
Prior art date
Application number
SG11201709573YA
Inventor
Yuji Ito
Original Assignee
Univ Kagoshima
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Kagoshima filed Critical Univ Kagoshima
Publication of SG11201709573YA publication Critical patent/SG11201709573YA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG11201709573YA 2015-05-20 2016-05-20 Specific modification of antibody with igg-binding peptide SG11201709573YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2015103153 2015-05-20
PCT/JP2016/065061 WO2016186206A1 (en) 2015-05-20 2016-05-20 SPECIFIC MODIFICATION OF ANTIBODY BY IgG-BINDING PEPTIDE

Publications (1)

Publication Number Publication Date
SG11201709573YA true SG11201709573YA (en) 2017-12-28

Family

ID=57320461

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201709573YA SG11201709573YA (en) 2015-05-20 2016-05-20 Specific modification of antibody with igg-binding peptide

Country Status (8)

Country Link
US (1) US10227383B2 (en)
EP (1) EP3299383A4 (en)
JP (2) JP6872181B2 (en)
KR (1) KR102651537B1 (en)
CN (1) CN107614514B (en)
CA (1) CA2985985A1 (en)
SG (1) SG11201709573YA (en)
WO (1) WO2016186206A1 (en)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201810923YA (en) * 2016-06-13 2019-01-30 Univ Kagoshima SITE-SPECIFIC RADIOISOTOPE-LABELED ANTIBODY USING IgG-BINDING PEPTIDE
CN109790202B (en) 2016-09-30 2022-09-13 富士胶片株式会社 Cyclic peptide, affinity chromatography carrier, labeled antibody, antibody drug complex and pharmaceutical preparation
WO2018092867A1 (en) * 2016-11-18 2018-05-24 国立大学法人鹿児島大学 Solid support containing igg-binding peptide, and method for separating igg
KR20200002858A (en) * 2017-04-28 2020-01-08 아지노모토 가부시키가이샤 Compounds having affinity, cleavable moieties and reactive groups for soluble proteins or salts thereof
WO2018230257A1 (en) * 2017-06-16 2018-12-20 国立大学法人鹿児島大学 IgG-BINDING PEPTIDE, AND SPECIFIC MODIFICATION OF ANTIBODY WITH SAID PEPTIDE
TW202003556A (en) 2018-04-16 2020-01-16 日商日本醫事物理股份有限公司 Modified antibody and radioactive metal-labelled antibody
WO2019240287A1 (en) 2018-06-14 2019-12-19 味の素株式会社 Compound comprising substance having affinity for antibody, cleavage site and reactive group, or salt thereof
EP3811978A4 (en) * 2018-06-14 2022-03-16 Ajinomoto Co., Inc. Substance having affinity for antibody, and compound or salt thereof having bioorthogonal functional group
JP2020019723A (en) * 2018-07-30 2020-02-06 国立大学法人 鹿児島大学 Complex of anti-CD70 antibody and IgG binding peptide
US20210380637A1 (en) * 2018-10-10 2021-12-09 Kagoshima University SOLID-PHASE CARRIER INCLUDING IgG-BINDING PEPTIDE, AND IgG SEPERATION METHOD
WO2020090979A1 (en) 2018-10-31 2020-05-07 味の素株式会社 Compound comprising substance with affinity for antibody, cleavage site and reactive group, or salt thereof
US20220072147A1 (en) * 2019-01-23 2022-03-10 AbTis Co., Ltd. Compound for preparation of antibody-payload conjugate and use thereof
KR102563319B1 (en) * 2019-03-08 2023-08-03 앱티스 주식회사 Site-specific antibody conjugation, and antibody-drug conjugate as its embodiment
CN114585393A (en) 2019-10-18 2022-06-03 日本医事物理股份有限公司 RI-labeled humanized antibodies
US20230248854A1 (en) * 2019-10-18 2023-08-10 Nihon Medi-Physics Co., Ltd. Method for producing radioactive metal-labeled antibody
JPWO2021080008A1 (en) 2019-10-24 2021-04-29
US20230210967A1 (en) 2020-04-23 2023-07-06 Brightpath Biotherapeutics Co., Ltd. Improved peptide vaccine
TW202216174A (en) 2020-06-30 2022-05-01 日商蓋亞生物製藥有限公司 Method for stabilizing binding of antibody to NK cell and use thereof
WO2022080385A1 (en) * 2020-10-13 2022-04-21 国立大学法人京都大学 Peptide, and modification of antibody with peptide
US20230390425A1 (en) 2020-10-16 2023-12-07 Nihon Medi-Physics Co., Ltd. Radioactive complexes of anti-her2 antibody, and radiopharmaceutical
CA3197961A1 (en) 2020-11-09 2022-05-12 Kagoshima University Peptide crosslinking agent and crosslinked peptide which is crosslinked using said crosslinking agent
JP2021049375A (en) * 2020-12-09 2021-04-01 株式会社三洋物産 Game machine
EP4276855A1 (en) 2021-01-08 2023-11-15 Nihon Medi-Physics Co., Ltd. Production method for ac-225 solution and production method for medicine using ac-225 solution
AU2022208654A1 (en) 2021-01-18 2023-08-03 Ajinomoto Co., Inc. Compound or salt thereof, and antibody produced using same
WO2022178754A1 (en) * 2021-02-25 2022-09-01 Shanghai Allygen Biologics Co., Ltd. Targeting conjugates with therapeutic agents and oligonucleotides and uses thereof
WO2022178753A1 (en) * 2021-02-25 2022-09-01 Shanghai Allygen Biologics Co., Ltd. Targeting conjugates comprising targeting moiety binding fragments and uses thereof
CN116964076A (en) 2021-03-11 2023-10-27 味之素株式会社 Compounds or salts thereof, and antibodies derived therefrom
WO2022196675A1 (en) 2021-03-16 2022-09-22 味の素株式会社 Complex or salt thereof, and method for manufacturing same
AU2022250323A1 (en) 2021-03-31 2023-11-09 Nihon Medi-Physics Co., Ltd. Radioactive complex of anti-egfr antibody, and radiopharmaceutical
JPWO2022224980A1 (en) 2021-04-20 2022-10-27
WO2022225007A1 (en) 2021-04-21 2022-10-27 日本メジフィジックス株式会社 Radioactive antitumor agent
CN117377696A (en) 2021-04-21 2024-01-09 日本医事物理股份有限公司 Humanized antibodies labeled with beta-emitting nuclides
CA3222359A1 (en) * 2021-07-09 2023-01-12 Bright Peak Therapeutics Ag Conjugates of checkpoint inhibitors with il-2, and uses thereof
TW202325343A (en) 2021-08-31 2023-07-01 日商日本醫事物理股份有限公司 Radioactive complex of deglycosylated antibody and radioactive pharmaceutical product
CA3231257A1 (en) 2021-09-08 2023-03-16 Yuji Ito Compound, salt of compound, antibody modification reagent, method for producing modified antibody, and modified antibody
WO2024096564A1 (en) * 2022-11-01 2024-05-10 앱티스 주식회사 Antibody-drug conjugate comprising anti-claudin-18.2 antibody, and therapeutic use thereof for cancer

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751286A (en) * 1985-11-19 1988-06-14 The Johns Hopkins University Protein label and drug delivery system
FR2604092B1 (en) 1986-09-19 1990-04-13 Immunotech Sa IMMUNOREACTIVES FOR TARGETING ANIMAL CELLS FOR VISUALIZATION OR DESTRUCTION IN VIVO
US6013763A (en) * 1996-06-04 2000-01-11 Genentech, Inc. Peptide variants of protein A
US7074405B1 (en) 1998-06-22 2006-07-11 Immunomedics, Inc. Use of bi-specific antibodies for pre-targeting diagnosis and therapy
WO2003101495A1 (en) 2002-05-29 2003-12-11 Immunomedics, Inc. Methods and compositions for radioimmunotherapy of brain and cns tumors
MX2011000647A (en) * 2008-07-18 2011-09-29 Trinity Therapeutics Inc Methods for treating immune-mediated dengue fever infections and antibody-dependent enhancement of dengue fever infections, including dengue hemorrhagic fever and dengue shock syndrome.
CN102892885B (en) * 2010-05-24 2015-08-19 国立大学法人鹿儿岛大学 IgA binding peptide and utilize its purifying of IgA
US8916689B2 (en) 2010-09-06 2014-12-23 GE Health Bio-Sciences AB Method for labeling of compounds
CN103890174B (en) * 2011-08-24 2015-12-23 大塚化学株式会社 IgG binding peptide and utilize it to detect and the method for IgG purification
SG11201810923YA (en) * 2016-06-13 2019-01-30 Univ Kagoshima SITE-SPECIFIC RADIOISOTOPE-LABELED ANTIBODY USING IgG-BINDING PEPTIDE
US20210380637A1 (en) * 2018-10-10 2021-12-09 Kagoshima University SOLID-PHASE CARRIER INCLUDING IgG-BINDING PEPTIDE, AND IgG SEPERATION METHOD

Also Published As

Publication number Publication date
JP7076152B2 (en) 2022-05-27
WO2016186206A1 (en) 2016-11-24
JP2020203940A (en) 2020-12-24
EP3299383A4 (en) 2019-01-23
EP3299383A1 (en) 2018-03-28
CA2985985A1 (en) 2016-11-24
US10227383B2 (en) 2019-03-12
KR102651537B1 (en) 2024-03-25
JP6872181B2 (en) 2021-05-19
CN107614514B (en) 2022-03-01
KR20180002734A (en) 2018-01-08
CN107614514A (en) 2018-01-19
US20180141976A1 (en) 2018-05-24
JPWO2016186206A1 (en) 2018-04-12

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