SG11201707166TA - Anti-inflammatory polypeptides - Google Patents

Anti-inflammatory polypeptides

Info

Publication number
SG11201707166TA
SG11201707166TA SG11201707166TA SG11201707166TA SG11201707166TA SG 11201707166T A SG11201707166T A SG 11201707166TA SG 11201707166T A SG11201707166T A SG 11201707166TA SG 11201707166T A SG11201707166T A SG 11201707166TA SG 11201707166T A SG11201707166T A SG 11201707166TA
Authority
SG
Singapore
Prior art keywords
inflammatory polypeptides
polypeptides
inflammatory
Prior art date
Application number
SG11201707166TA
Inventor
Jeffrey V Ravetch
Andrew Pincetic
Original Assignee
Univ Rockefeller
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US14/638,905 external-priority patent/US9845358B2/en
Application filed by Univ Rockefeller filed Critical Univ Rockefeller
Publication of SG11201707166TA publication Critical patent/SG11201707166TA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/40Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41Glycosylation, sialylation, or fucosylation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • C07K2317/524CH2 domain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/54F(ab')2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/72Increased effector function due to an Fc-modification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2318/00Antibody mimetics or scaffolds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Transplantation (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SG11201707166TA 2015-03-04 2016-03-04 Anti-inflammatory polypeptides SG11201707166TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14/638,905 US9845358B2 (en) 2011-12-19 2015-03-04 Anti-inflammatory polypeptides
PCT/US2016/020813 WO2016141262A1 (en) 2015-03-04 2016-03-04 Anti-inflammatory polypeptides

Publications (1)

Publication Number Publication Date
SG11201707166TA true SG11201707166TA (en) 2017-09-28

Family

ID=56848864

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201707166TA SG11201707166TA (en) 2015-03-04 2016-03-04 Anti-inflammatory polypeptides

Country Status (11)

Country Link
US (1) US10844125B2 (en)
EP (1) EP3265124A4 (en)
JP (1) JP2018508522A (en)
KR (1) KR20230028600A (en)
CN (1) CN107847586A (en)
AU (1) AU2016226115B2 (en)
CA (1) CA2978580A1 (en)
EA (2) EA202191471A1 (en)
IL (1) IL254284B2 (en)
SG (1) SG11201707166TA (en)
WO (1) WO2016141262A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8470318B2 (en) * 2005-11-07 2013-06-25 The Rockefeller University Polypeptides with enhanced anti-inflammatory and decreased cytotoxic properties and relating methods
JP7122002B2 (en) * 2017-03-01 2022-08-19 国立大学法人北海道大学 Method for producing a disease model non-human animal, disease model non-human animal, drug screening method using the animal, and disease risk determination method
CN112924671A (en) * 2021-01-28 2021-06-08 中国医学科学院北京协和医院 Biomarker for diagnosing rheumatoid arthritis combined with pulmonary interstitial fibrosis and application thereof
WO2023104128A1 (en) 2021-12-09 2023-06-15 上海宝济药业有限公司 Fc polypeptide having altered glycosylation modification
WO2024071010A1 (en) * 2022-09-26 2024-04-04 国立大学法人京都大学 T cell production method

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7064191B2 (en) 2000-10-06 2006-06-20 Kyowa Hakko Kogyo Co., Ltd. Process for purifying antibody
US20040002587A1 (en) 2002-02-20 2004-01-01 Watkins Jeffry D. Fc region variants
US8188231B2 (en) 2002-09-27 2012-05-29 Xencor, Inc. Optimized FC variants
CA2595169A1 (en) 2005-01-12 2006-07-20 Xencor, Inc. Antibodies and fc fusion proteins with altered immunogenicity
BRPI0611445A2 (en) 2005-05-09 2010-09-08 Glycart Biotechnology Ag glycomanipulated antigen binding molecule, polynucleotide, polypeptide, vector, host cell, method for production, use and pharmaceutical composition
DK1896071T3 (en) 2005-06-30 2015-05-26 Janssen Biotech Inc Methods and compositions with increased therapeutic activity
WO2007055916A2 (en) 2005-11-07 2007-05-18 The Rockefeller University Reagents, methods and systems for selecting a cytotoxic antibody or variant thereof
US8470318B2 (en) * 2005-11-07 2013-06-25 The Rockefeller University Polypeptides with enhanced anti-inflammatory and decreased cytotoxic properties and relating methods
EP3456351A1 (en) 2006-04-05 2019-03-20 The Rockefeller University Polypeptides with enhanced anti-inflammatory and decreased cytotoxic properties and relating methods
NZ597651A (en) 2006-10-26 2012-07-27 Univ Rockefeller Polypeptides with enhanced anti-inflammatory and decreased cytotoxic properties and relating methods
MX2009006659A (en) 2006-12-20 2009-10-12 Mmr Information Systems Inc Antibodies and methods for making and using them.
US8540992B2 (en) 2006-12-28 2013-09-24 Michael Naso Methods and vectors for generating asialylated immunoglobulins
US20110020269A1 (en) * 2007-05-08 2011-01-27 Beth Israel Deaconess Medical Center, Inc. Methods and compositions for modifying t cell immune responses and inflammation
CN101687933B (en) 2007-05-30 2015-11-25 浦项工科大学校产学协力团 Domain-immunoglobulin fusion proteins
JP5647899B2 (en) 2008-01-08 2015-01-07 ラツィオファルム ゲーエムベーハーratiopharm GmbH Glycoconjugation of polypeptides using oligosaccharyltransferase
EP2279410B1 (en) 2008-04-22 2015-11-11 The Rockefeller University Methods of identifying anti-inflammatory compounds
WO2011059684A1 (en) 2009-10-29 2011-05-19 Centocor Ortho Biotech Inc. Antibody glycosylation variants
TW202323302A (en) 2010-11-30 2023-06-16 日商中外製藥股份有限公司 Cytotoxicity-inducing therapeutic agent
US20120258041A1 (en) 2011-04-07 2012-10-11 Basi Guriqbal S Compositions and methods for treating diseases of protein aggregation involving ic3b deposition
BR112014014549A2 (en) * 2011-12-19 2020-09-24 The Rockefeller University non-sialylated popipeptide anti-inflammatory

Also Published As

Publication number Publication date
US10844125B2 (en) 2020-11-24
JP2018508522A (en) 2018-03-29
IL254284B1 (en) 2023-03-01
US20180051087A1 (en) 2018-02-22
EA038554B1 (en) 2021-09-14
EP3265124A4 (en) 2018-09-12
EP3265124A1 (en) 2018-01-10
CA2978580A1 (en) 2016-09-09
AU2016226115A1 (en) 2017-10-19
AU2016226115B2 (en) 2021-03-25
IL254284B2 (en) 2023-07-01
EA201791937A1 (en) 2018-07-31
CN107847586A (en) 2018-03-27
KR20230028600A (en) 2023-02-28
WO2016141262A1 (en) 2016-09-09
IL254284A0 (en) 2017-10-31
EA202191471A1 (en) 2022-01-31

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