SG11201607580VA - Disposable bioreactor with acoustophoresis device - Google Patents

Disposable bioreactor with acoustophoresis device

Info

Publication number
SG11201607580VA
SG11201607580VA SG11201607580VA SG11201607580VA SG11201607580VA SG 11201607580V A SG11201607580V A SG 11201607580VA SG 11201607580V A SG11201607580V A SG 11201607580VA SG 11201607580V A SG11201607580V A SG 11201607580VA SG 11201607580V A SG11201607580V A SG 11201607580VA
Authority
SG
Singapore
Prior art keywords
disposable bioreactor
acoustophoresis device
acoustophoresis
bioreactor
disposable
Prior art date
Application number
SG11201607580VA
Other languages
English (en)
Inventor
Bart Lipkens
Louis Masi
Walter M Presz Jr
Thomas J Kennedy Iii
Original Assignee
Flodesign Sonics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Flodesign Sonics Inc filed Critical Flodesign Sonics Inc
Publication of SG11201607580VA publication Critical patent/SG11201607580VA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/10Separation or concentration of fermentation products
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/02Form or structure of the vessel
    • C12M23/14Bags
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/26Constructional details, e.g. recesses, hinges flexible
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/28Constructional details, e.g. recesses, hinges disposable or single use
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/02Stirrer or mobile mixing elements
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/44Means for regulation, monitoring, measurement or control, e.g. flow regulation of volume or liquid level
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/02Separating microorganisms from the culture medium; Concentration of biomass

Landscapes

  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Clinical Laboratory Science (AREA)
  • Analytical Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SG11201607580VA 2014-03-10 2015-03-10 Disposable bioreactor with acoustophoresis device SG11201607580VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461950309P 2014-03-10 2014-03-10
PCT/US2015/019755 WO2015138489A1 (en) 2014-03-10 2015-03-10 Disposable bioreactor with acoustophoresis device

Publications (1)

Publication Number Publication Date
SG11201607580VA true SG11201607580VA (en) 2016-10-28

Family

ID=52684755

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201607580VA SG11201607580VA (en) 2014-03-10 2015-03-10 Disposable bioreactor with acoustophoresis device

Country Status (7)

Country Link
US (1) US20150252317A1 (ru)
EP (1) EP3116987A1 (ru)
CN (1) CN106414702A (ru)
CA (1) CA2942331A1 (ru)
RU (1) RU2016139366A (ru)
SG (1) SG11201607580VA (ru)
WO (1) WO2015138489A1 (ru)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10689609B2 (en) 2012-03-15 2020-06-23 Flodesign Sonics, Inc. Acoustic bioreactor processes
US10322949B2 (en) 2012-03-15 2019-06-18 Flodesign Sonics, Inc. Transducer and reflector configurations for an acoustophoretic device
US10704021B2 (en) 2012-03-15 2020-07-07 Flodesign Sonics, Inc. Acoustic perfusion devices
US9752113B2 (en) 2012-03-15 2017-09-05 Flodesign Sonics, Inc. Acoustic perfusion devices
US9458450B2 (en) 2012-03-15 2016-10-04 Flodesign Sonics, Inc. Acoustophoretic separation technology using multi-dimensional standing waves
US10967298B2 (en) 2012-03-15 2021-04-06 Flodesign Sonics, Inc. Driver and control for variable impedence load
US9745548B2 (en) 2012-03-15 2017-08-29 Flodesign Sonics, Inc. Acoustic perfusion devices
US9950282B2 (en) 2012-03-15 2018-04-24 Flodesign Sonics, Inc. Electronic configuration and control for acoustic standing wave generation
US10737953B2 (en) 2012-04-20 2020-08-11 Flodesign Sonics, Inc. Acoustophoretic method for use in bioreactors
US9745569B2 (en) 2013-09-13 2017-08-29 Flodesign Sonics, Inc. System for generating high concentration factors for low cell density suspensions
WO2015105955A1 (en) 2014-01-08 2015-07-16 Flodesign Sonics, Inc. Acoustophoresis device with dual acoustophoretic chamber
US9744483B2 (en) 2014-07-02 2017-08-29 Flodesign Sonics, Inc. Large scale acoustic separation device
WO2016152697A1 (ja) * 2015-03-20 2016-09-29 積水化学工業株式会社 微生物の培養方法及び培養装置
US11377651B2 (en) 2016-10-19 2022-07-05 Flodesign Sonics, Inc. Cell therapy processes utilizing acoustophoresis
CA2984492A1 (en) 2015-04-29 2016-11-03 Flodesign Sonics, Inc. Acoustophoretic device for angled wave particle deflection
US11021699B2 (en) 2015-04-29 2021-06-01 FioDesign Sonics, Inc. Separation using angled acoustic waves
US11708572B2 (en) 2015-04-29 2023-07-25 Flodesign Sonics, Inc. Acoustic cell separation techniques and processes
US11459540B2 (en) 2015-07-28 2022-10-04 Flodesign Sonics, Inc. Expanded bed affinity selection
US11474085B2 (en) 2015-07-28 2022-10-18 Flodesign Sonics, Inc. Expanded bed affinity selection
US11085035B2 (en) 2016-05-03 2021-08-10 Flodesign Sonics, Inc. Therapeutic cell washing, concentration, and separation utilizing acoustophoresis
US11214789B2 (en) 2016-05-03 2022-01-04 Flodesign Sonics, Inc. Concentration and washing of particles with acoustics
CA3041517A1 (en) 2016-10-19 2018-04-26 Flodesign Sonics, Inc. Affinity cell extraction by acoustics
KR102410357B1 (ko) * 2016-11-11 2022-06-16 오리바이오테크 엘티디 세포 배양 장치 시스템 및 그의 사용 방법
DE102017208758A1 (de) * 2017-05-23 2018-11-29 Valentin Kramer Vorrichtung und Verfahren zur Kultivierung von Zellen
EP3725092A4 (en) 2017-12-14 2021-09-22 FloDesign Sonics, Inc. DRIVE AND CONTROL UNIT FOR ACOUSTIC CONVERTER
WO2020141327A1 (en) * 2019-01-04 2020-07-09 Oribiotech Ltd Cell processing device cell processing system and methods of use thereof
GB2592566B (en) * 2020-01-13 2022-05-18 Oribiotech Ltd An apparatus for, and a method of, processing cells
EP3854867A1 (de) * 2020-01-23 2021-07-28 FRAUNHOFER-GESELLSCHAFT zur Förderung der angewandten Forschung e.V. Vorkehrung zur kultivierung von prokryotischen und eukaryotischen zellen in einer strukturierten matrix unter physikalischer kräfteeinwirkung
GB2613170A (en) * 2021-11-25 2023-05-31 Oribiotech Ltd A bioreactor comprising a baffle

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1260343C (zh) * 2002-01-31 2006-06-21 赛宇细胞科技股份有限公司 细胞培养装置
US20070224676A1 (en) * 2006-03-21 2007-09-27 Becton, Dickinson And Company Expandable culture roller bottle
US8381780B2 (en) * 2008-05-22 2013-02-26 Xcellerex, Inc. Lift and support assemblies and methods for collapsible bag containers of vessels and bioreactors
US20110163013A1 (en) * 2008-05-30 2011-07-07 Eppendorf Ag Apparatus and Method for Moving Particles in a Fluid
JP2012517829A (ja) * 2009-02-18 2012-08-09 バイオレックス・セラピューティクス インコーポレイテッド 生体材料を処理するための無菌バイオリアクタ・システム
EP2470638B1 (en) * 2009-08-26 2019-10-23 GE Healthcare Bio-Sciences Corp. Continuous recovery harvest bag
US8592204B2 (en) * 2010-08-23 2013-11-26 Flodesign Sonics, Inc. Ultrasound and acoustophoresis for collection and processing of oleaginous microorganisms
US9314751B2 (en) * 2011-01-07 2016-04-19 Life Technologies Corporation Methods and apparatus for mixing and shipping fluids
US9376655B2 (en) * 2011-09-29 2016-06-28 Life Technologies Corporation Filter systems for separating microcarriers from cell culture solutions
US9688958B2 (en) * 2012-03-15 2017-06-27 Flodesign Sonics, Inc. Acoustic bioreactor processes
WO2013138797A1 (en) * 2012-03-15 2013-09-19 Flodesign Sonics, Inc. Acoustophoretic multi-component separation technology platform
US8709250B2 (en) * 2012-07-12 2014-04-29 Heliae Development, Llc Tubular electro-acoustic aggregation device

Also Published As

Publication number Publication date
US20150252317A1 (en) 2015-09-10
CN106414702A (zh) 2017-02-15
WO2015138489A1 (en) 2015-09-17
CA2942331A1 (en) 2015-09-17
EP3116987A1 (en) 2017-01-18
RU2016139366A (ru) 2018-04-13

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