SG11201606862VA - Process for preparing n-benzyl-3-hydroxy-4-substituted-pyridin-2-(1h)-ones - Google Patents
Process for preparing n-benzyl-3-hydroxy-4-substituted-pyridin-2-(1h)-onesInfo
- Publication number
- SG11201606862VA SG11201606862VA SG11201606862VA SG11201606862VA SG11201606862VA SG 11201606862V A SG11201606862V A SG 11201606862VA SG 11201606862V A SG11201606862V A SG 11201606862VA SG 11201606862V A SG11201606862V A SG 11201606862VA SG 11201606862V A SG11201606862V A SG 11201606862VA
- Authority
- SG
- Singapore
- Prior art keywords
- pyridin
- benzyl
- hydroxy
- ones
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/69—Two or more oxygen atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461941540P | 2014-02-19 | 2014-02-19 | |
| PCT/US2015/016243 WO2015126860A1 (fr) | 2014-02-19 | 2015-02-18 | Procédé de préparation de n-benzyl-3-hydroxy-4-substitué-pyridine-2-(1h)-ones |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201606862VA true SG11201606862VA (en) | 2016-09-29 |
Family
ID=53797499
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201606862VA SG11201606862VA (en) | 2014-02-19 | 2015-02-18 | Process for preparing n-benzyl-3-hydroxy-4-substituted-pyridin-2-(1h)-ones |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9388135B2 (fr) |
| EP (1) | EP3107542B1 (fr) |
| JP (1) | JP6549140B2 (fr) |
| CN (1) | CN106232120B (fr) |
| ES (1) | ES2739625T3 (fr) |
| SG (1) | SG11201606862VA (fr) |
| WO (1) | WO2015126860A1 (fr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7622593B2 (en) | 2006-06-27 | 2009-11-24 | The Procter & Gamble Company | Human protein tyrosine phosphatase inhibitors and methods of use |
| MY160399A (en) | 2009-07-06 | 2017-03-15 | Aerpio Therapeutics Inc | Compounds, compositions, and methods for preventing metastasis of cancer cells |
| CA2774046C (fr) | 2009-11-06 | 2014-01-21 | Aerpio Therapeutics Inc. | Compositions comprenant du n-benzyl ou du n-sulfonylaryl-3-hydroxypyridine-2-(1h)-ones et leur utilisation pour traiter les colites |
| WO2013056240A1 (fr) | 2011-10-13 | 2013-04-18 | Aerpio Therapeutics, Inc. | Méthodes de traitement du syndrome de fuite vasculaire et du cancer |
| GB2516561B (en) | 2013-03-15 | 2016-03-09 | Aerpio Therapeutics Inc | Compositions, formulations and methods for treating ocular diseases |
| US20150050277A1 (en) | 2013-03-15 | 2015-02-19 | Aerpio Therapeutics Inc. | Compositions and methods for treating ocular diseases |
| US9539245B2 (en) | 2014-08-07 | 2017-01-10 | Aerpio Therapeutics, Inc. | Combination of immunotherapies with activators of Tie-2 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4508898A (en) * | 1980-09-16 | 1985-04-02 | Ogilvie Kelvin K | Antiviral triazine compounds |
| US7507568B2 (en) | 2002-09-25 | 2009-03-24 | The Proctor & Gamble Company | Three dimensional coordinates of HPTPbeta |
| US7226755B1 (en) | 2002-09-25 | 2007-06-05 | The Procter & Gamble Company | HPTPbeta as a target in treatment of angiogenesis mediated disorders |
| US6930117B2 (en) | 2002-11-09 | 2005-08-16 | The Procter & Gamble Company | N-alkyl-4-methyleneamino-3-hydroxy-2-pyridones |
| US6946479B2 (en) | 2002-11-09 | 2005-09-20 | The Procter & Gamble Company | N-sulfonyl-4-methyleneamino-3-hydroxy-2-pyridones |
| BRPI0710645A2 (pt) | 2006-04-07 | 2012-03-20 | The Procter & Gamble Company | Anticorpos que se ligam à proteína humana tirosina fosfatase beta (hptpbeta) e usos dos mesmos |
| PE20080209A1 (es) | 2006-06-23 | 2008-05-15 | Smithkline Beecham Corp | Derivados de glicina como inhibidores de prolil hidroxilasa |
| EP4095127A1 (fr) * | 2006-06-26 | 2022-11-30 | Akebia Therapeutics Inc. | Inhibiteurs de prolyl hydroxylase et procédés d'utilisation |
| US7795444B2 (en) | 2006-06-27 | 2010-09-14 | Warner Chilcott Company | Human protein tyrosine phosphatase inhibitors and methods of use |
| US20130023542A1 (en) | 2006-06-27 | 2013-01-24 | Aerpio Therapeutics Inc. | Human protein tyrosine phosphatase inhibitors and methods of use |
| US8846685B2 (en) | 2006-06-27 | 2014-09-30 | Aerpio Therapeutics Inc. | Human protein tyrosine phosphatase inhibitors and methods of use |
| US7622593B2 (en) | 2006-06-27 | 2009-11-24 | The Procter & Gamble Company | Human protein tyrosine phosphatase inhibitors and methods of use |
| US7589212B2 (en) | 2006-06-27 | 2009-09-15 | Procter & Gamble Company | Human protein tyrosine phosphatase inhibitors and methods of use |
| US9096555B2 (en) | 2009-01-12 | 2015-08-04 | Aerpio Therapeutics, Inc. | Methods for treating vascular leak syndrome |
| SG172312A1 (en) | 2009-01-12 | 2011-07-28 | Akebia Therapeutics Inc | Methods for treating vascular leak syndrome |
| MY160399A (en) | 2009-07-06 | 2017-03-15 | Aerpio Therapeutics Inc | Compounds, compositions, and methods for preventing metastasis of cancer cells |
| US8883832B2 (en) | 2009-07-06 | 2014-11-11 | Aerpio Therapeutics Inc. | Compounds, compositions, and methods for preventing metastasis of cancer cells |
| CA2774046C (fr) * | 2009-11-06 | 2014-01-21 | Aerpio Therapeutics Inc. | Compositions comprenant du n-benzyl ou du n-sulfonylaryl-3-hydroxypyridine-2-(1h)-ones et leur utilisation pour traiter les colites |
| NZ705624A (en) | 2010-10-07 | 2016-09-30 | Aerpio Therapeutics Inc | Compositions and methods for treating ocular edema, neovascularization and related diseases |
| BR112014008759A8 (pt) | 2011-10-13 | 2017-09-12 | Aerpio Therapeutics Inc | Tratamento de doença ocular |
| WO2013056240A1 (fr) | 2011-10-13 | 2013-04-18 | Aerpio Therapeutics, Inc. | Méthodes de traitement du syndrome de fuite vasculaire et du cancer |
| US20150050277A1 (en) | 2013-03-15 | 2015-02-19 | Aerpio Therapeutics Inc. | Compositions and methods for treating ocular diseases |
| GB2516561B (en) | 2013-03-15 | 2016-03-09 | Aerpio Therapeutics Inc | Compositions, formulations and methods for treating ocular diseases |
-
2015
- 2015-02-18 SG SG11201606862VA patent/SG11201606862VA/en unknown
- 2015-02-18 ES ES15751652T patent/ES2739625T3/es active Active
- 2015-02-18 EP EP15751652.7A patent/EP3107542B1/fr active Active
- 2015-02-18 WO PCT/US2015/016243 patent/WO2015126860A1/fr active Application Filing
- 2015-02-18 JP JP2016552980A patent/JP6549140B2/ja not_active Expired - Fee Related
- 2015-02-18 US US14/624,625 patent/US9388135B2/en not_active Expired - Fee Related
- 2015-02-18 CN CN201580020246.8A patent/CN106232120B/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20150232425A1 (en) | 2015-08-20 |
| EP3107542A4 (fr) | 2017-08-23 |
| ES2739625T3 (es) | 2020-02-03 |
| EP3107542A1 (fr) | 2016-12-28 |
| US9388135B2 (en) | 2016-07-12 |
| JP2017509608A (ja) | 2017-04-06 |
| EP3107542B1 (fr) | 2019-05-01 |
| CN106232120A (zh) | 2016-12-14 |
| WO2015126860A1 (fr) | 2015-08-27 |
| CN106232120B (zh) | 2021-01-08 |
| JP6549140B2 (ja) | 2019-07-24 |
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