SG11201606862VA - Process for preparing n-benzyl-3-hydroxy-4-substituted-pyridin-2-(1h)-ones - Google Patents
Process for preparing n-benzyl-3-hydroxy-4-substituted-pyridin-2-(1h)-onesInfo
- Publication number
- SG11201606862VA SG11201606862VA SG11201606862VA SG11201606862VA SG11201606862VA SG 11201606862V A SG11201606862V A SG 11201606862VA SG 11201606862V A SG11201606862V A SG 11201606862VA SG 11201606862V A SG11201606862V A SG 11201606862VA SG 11201606862V A SG11201606862V A SG 11201606862VA
- Authority
- SG
- Singapore
- Prior art keywords
- pyridin
- benzyl
- hydroxy
- ones
- substituted
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/69—Two or more oxygen atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461941540P | 2014-02-19 | 2014-02-19 | |
| PCT/US2015/016243 WO2015126860A1 (en) | 2014-02-19 | 2015-02-18 | Process for preparing n-benzyl-3-hydroxy-4-substituted-pyridin-2-(1h)-ones |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201606862VA true SG11201606862VA (en) | 2016-09-29 |
Family
ID=53797499
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201606862VA SG11201606862VA (en) | 2014-02-19 | 2015-02-18 | Process for preparing n-benzyl-3-hydroxy-4-substituted-pyridin-2-(1h)-ones |
Country Status (7)
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7622593B2 (en) | 2006-06-27 | 2009-11-24 | The Procter & Gamble Company | Human protein tyrosine phosphatase inhibitors and methods of use |
| SG172313A1 (en) | 2009-07-06 | 2011-07-28 | Akebia Therapeutics Inc | Compounds, compositions, and methods for preventing metastasis of cancer cells |
| EP2496082B1 (en) | 2009-11-06 | 2016-10-12 | Aerpio Therapeutics, Inc. | Methods for increasing the stabilization of hypoxia inducible factor-1 alpha |
| MX363351B (es) | 2011-10-13 | 2019-03-20 | Aerpio Therapeutics Inc | Un agente de unión a hptp?-ecd para usarse en el tratamiento de síndrome de fuga vascular. |
| US20150050277A1 (en) | 2013-03-15 | 2015-02-19 | Aerpio Therapeutics Inc. | Compositions and methods for treating ocular diseases |
| WO2014145068A1 (en) | 2013-03-15 | 2014-09-18 | Aerpio Therapeutics Inc. | Compositions, formulations and methods for treating ocular diseases |
| WO2016022813A1 (en) | 2014-08-07 | 2016-02-11 | Aerpio Therapeutics, Inc. | Combination of immunotherapies with activators of tie-2 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4508898A (en) * | 1980-09-16 | 1985-04-02 | Ogilvie Kelvin K | Antiviral triazine compounds |
| US7226755B1 (en) | 2002-09-25 | 2007-06-05 | The Procter & Gamble Company | HPTPbeta as a target in treatment of angiogenesis mediated disorders |
| US7507568B2 (en) | 2002-09-25 | 2009-03-24 | The Proctor & Gamble Company | Three dimensional coordinates of HPTPbeta |
| US6930117B2 (en) | 2002-11-09 | 2005-08-16 | The Procter & Gamble Company | N-alkyl-4-methyleneamino-3-hydroxy-2-pyridones |
| US6946479B2 (en) | 2002-11-09 | 2005-09-20 | The Procter & Gamble Company | N-sulfonyl-4-methyleneamino-3-hydroxy-2-pyridones |
| BRPI0710645A2 (pt) | 2006-04-07 | 2012-03-20 | The Procter & Gamble Company | Anticorpos que se ligam à proteína humana tirosina fosfatase beta (hptpbeta) e usos dos mesmos |
| TWI394747B (zh) * | 2006-06-23 | 2013-05-01 | Smithkline Beecham Corp | 脯胺醯基羥化酶抑制劑 |
| KR101130592B1 (ko) * | 2006-06-26 | 2012-04-02 | 워너 칠콧 컴퍼니 엘엘씨 | 프롤릴 히드록실라제 저해제 및 사용 방법 |
| US20130023542A1 (en) | 2006-06-27 | 2013-01-24 | Aerpio Therapeutics Inc. | Human protein tyrosine phosphatase inhibitors and methods of use |
| US7589212B2 (en) | 2006-06-27 | 2009-09-15 | Procter & Gamble Company | Human protein tyrosine phosphatase inhibitors and methods of use |
| US7622593B2 (en) | 2006-06-27 | 2009-11-24 | The Procter & Gamble Company | Human protein tyrosine phosphatase inhibitors and methods of use |
| US7795444B2 (en) | 2006-06-27 | 2010-09-14 | Warner Chilcott Company | Human protein tyrosine phosphatase inhibitors and methods of use |
| US8846685B2 (en) | 2006-06-27 | 2014-09-30 | Aerpio Therapeutics Inc. | Human protein tyrosine phosphatase inhibitors and methods of use |
| EP2385763B1 (en) | 2009-01-12 | 2018-04-18 | Aerpio Therapeutics, Inc. | Methods for treating vascular leak syndrome |
| US9096555B2 (en) | 2009-01-12 | 2015-08-04 | Aerpio Therapeutics, Inc. | Methods for treating vascular leak syndrome |
| US8883832B2 (en) | 2009-07-06 | 2014-11-11 | Aerpio Therapeutics Inc. | Compounds, compositions, and methods for preventing metastasis of cancer cells |
| SG172313A1 (en) | 2009-07-06 | 2011-07-28 | Akebia Therapeutics Inc | Compounds, compositions, and methods for preventing metastasis of cancer cells |
| EP2496082B1 (en) | 2009-11-06 | 2016-10-12 | Aerpio Therapeutics, Inc. | Methods for increasing the stabilization of hypoxia inducible factor-1 alpha |
| MY176514A (en) | 2010-10-07 | 2020-08-12 | Aerpio Therapeutics Inc | Compositions and methods for treating ocular edema, neovascularization and related diseases |
| MX363351B (es) | 2011-10-13 | 2019-03-20 | Aerpio Therapeutics Inc | Un agente de unión a hptp?-ecd para usarse en el tratamiento de síndrome de fuga vascular. |
| EP3501536A1 (en) | 2011-10-13 | 2019-06-26 | Aerpio Therapeutics, Inc. | Treatment of ocular disease |
| WO2014145068A1 (en) | 2013-03-15 | 2014-09-18 | Aerpio Therapeutics Inc. | Compositions, formulations and methods for treating ocular diseases |
| US20150050277A1 (en) | 2013-03-15 | 2015-02-19 | Aerpio Therapeutics Inc. | Compositions and methods for treating ocular diseases |
-
2015
- 2015-02-18 SG SG11201606862VA patent/SG11201606862VA/en unknown
- 2015-02-18 US US14/624,625 patent/US9388135B2/en not_active Expired - Fee Related
- 2015-02-18 EP EP15751652.7A patent/EP3107542B1/en active Active
- 2015-02-18 ES ES15751652T patent/ES2739625T3/es active Active
- 2015-02-18 JP JP2016552980A patent/JP6549140B2/ja not_active Expired - Fee Related
- 2015-02-18 CN CN201580020246.8A patent/CN106232120B/zh not_active Expired - Fee Related
- 2015-02-18 WO PCT/US2015/016243 patent/WO2015126860A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| JP2017509608A (ja) | 2017-04-06 |
| CN106232120B (zh) | 2021-01-08 |
| EP3107542A1 (en) | 2016-12-28 |
| EP3107542A4 (en) | 2017-08-23 |
| CN106232120A (zh) | 2016-12-14 |
| WO2015126860A1 (en) | 2015-08-27 |
| US9388135B2 (en) | 2016-07-12 |
| JP6549140B2 (ja) | 2019-07-24 |
| ES2739625T3 (es) | 2020-02-03 |
| US20150232425A1 (en) | 2015-08-20 |
| EP3107542B1 (en) | 2019-05-01 |
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