SG11201606762PA - Combination - Google Patents

Combination

Info

Publication number
SG11201606762PA
SG11201606762PA SG11201606762PA SG11201606762PA SG11201606762PA SG 11201606762P A SG11201606762P A SG 11201606762PA SG 11201606762P A SG11201606762P A SG 11201606762PA SG 11201606762P A SG11201606762P A SG 11201606762PA SG 11201606762P A SG11201606762P A SG 11201606762PA
Authority
SG
Singapore
Prior art keywords
combination
Prior art date
Application number
SG11201606762PA
Inventor
Marina Nuria Godessart
Pelaez Cristina Balague
Original Assignee
Almirall Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to EP14382192 priority Critical
Priority to EP14382401 priority
Priority to EP14382400 priority
Application filed by Almirall Sa filed Critical Almirall Sa
Priority to PCT/EP2015/061312 priority patent/WO2015181055A1/en
Publication of SG11201606762PA publication Critical patent/SG11201606762PA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/53Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane, progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane, progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01Sulfonic acids
    • C07C309/02Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/04Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing only one sulfo group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01Sulfonic acids
    • C07C309/28Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/29Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton of non-condensed six-membered aromatic rings
    • C07C309/30Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton of non-condensed six-membered aromatic rings of six-membered aromatic rings substituted by alkyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01Sulfonic acids
    • C07C309/28Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/33Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton of six-membered aromatic rings being part of condensed ring systems
    • C07C309/34Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton of six-membered aromatic rings being part of condensed ring systems formed by two rings
    • C07C309/35Naphthalene sulfonic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs
SG11201606762PA 2014-05-27 2015-05-21 Combination SG11201606762PA (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP14382192 2014-05-27
EP14382401 2014-10-17
EP14382400 2014-10-17
PCT/EP2015/061312 WO2015181055A1 (en) 2014-05-27 2015-05-21 Combination

Publications (1)

Publication Number Publication Date
SG11201606762PA true SG11201606762PA (en) 2016-09-29

Family

ID=53269467

Family Applications (3)

Application Number Title Priority Date Filing Date
SG11201607950SA SG11201607950SA (en) 2014-05-27 2015-05-21 Addition salts of (s)-2-(1-(6-amino-5-cyanopyrimidin-4-ylamino)ethyl)-4-oxo-3-phenyl-3,4-dihydropyrrolo[1,2-f][1,2,4]triazine-5-carbonitrile
SG11201606762PA SG11201606762PA (en) 2014-05-27 2015-05-21 Combination
SG11201606763VA SG11201606763VA (en) 2014-05-27 2015-05-21 Medical use

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG11201607950SA SG11201607950SA (en) 2014-05-27 2015-05-21 Addition salts of (s)-2-(1-(6-amino-5-cyanopyrimidin-4-ylamino)ethyl)-4-oxo-3-phenyl-3,4-dihydropyrrolo[1,2-f][1,2,4]triazine-5-carbonitrile

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201606763VA SG11201606763VA (en) 2014-05-27 2015-05-21 Medical use

Country Status (20)

Country Link
US (3) US20170151264A1 (en)
EP (3) EP3148999A1 (en)
JP (3) JP2017516797A (en)
KR (3) KR20170012236A (en)
CN (3) CN107074862A (en)
AU (3) AU2015266193A1 (en)
BR (1) BR112016024538A2 (en)
CA (3) CA2941436A1 (en)
CL (2) CL2016002971A1 (en)
CR (3) CR20160538A (en)
EA (3) EA201692435A1 (en)
IL (3) IL247072D0 (en)
MD (3) MD20160138A2 (en)
MX (3) MX2016014904A (en)
PE (2) PE20170145A1 (en)
PH (3) PH12016502252A1 (en)
SG (3) SG11201607950SA (en)
TW (3) TW201625259A (en)
UY (3) UY36151A (en)
WO (3) WO2015181053A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8193182B2 (en) 2008-01-04 2012-06-05 Intellikine, Inc. Substituted isoquinolin-1(2H)-ones, and methods of use thereof
SG187425A1 (en) 2008-01-04 2013-02-28 Intellikine Llc Certain chemical entities, compositions and methods
UA115767C2 (en) 2011-01-10 2017-12-26 Інфініті Фармасьютікалз, Інк. Processes for preparing isoquinolinones and solid forms of isoquinolinones
US8828998B2 (en) 2012-06-25 2014-09-09 Infinity Pharmaceuticals, Inc. Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors
EP2948134A4 (en) 2013-01-24 2016-08-24 Transderm Inc COMPOSITIONS FOR TRANSDERMAL DELIVERY OF mTOR INHIBITORS
WO2019101853A1 (en) * 2017-11-23 2019-05-31 Piqur Therapeutics Ag Treatment of skin disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008501707A (en) * 2004-06-04 2008-01-24 アイコス、コーポレーションIcos Corporation Methods for treating mast cell disorders
MX2008002723A (en) * 2005-08-26 2008-03-26 Serono Lab Pyrazine derivatives and use as pi3k inhibitors.
JP2012521994A (en) * 2009-03-24 2012-09-20 ギリアード カリストガ エルエルシー Atropisomers of 2-prinyl-3-tolyl-quinazolinone derivatives and methods of use
EP2518070A1 (en) * 2011-04-29 2012-10-31 Almirall, S.A. Pyrrolotriazinone derivatives as PI3K inhibitors

Also Published As

Publication number Publication date
CN107074862A (en) 2017-08-18
BR112016024538A2 (en) 2017-08-15
KR20170010369A (en) 2017-01-31
PE20170385A1 (en) 2017-04-09
MD20160137A2 (en) 2017-05-31
US20170189409A1 (en) 2017-07-06
CA2941436A1 (en) 2015-12-03
US20170151264A1 (en) 2017-06-01
JP2017516799A (en) 2017-06-22
CR20160537A (en) 2017-03-17
MX2016014864A (en) 2017-04-06
WO2015181052A1 (en) 2015-12-03
AU2015266190A1 (en) 2016-10-20
PH12016502252A1 (en) 2017-02-06
AU2015266193A1 (en) 2016-09-15
MX2016014861A (en) 2017-04-06
AU2015266191A1 (en) 2016-09-15
PH12016502255A1 (en) 2017-02-06
SG11201606763VA (en) 2016-09-29
TW201625259A (en) 2016-07-16
JP2017516798A (en) 2017-06-22
CR20160536A (en) 2017-01-02
CA2944611A1 (en) 2015-12-03
WO2015181053A1 (en) 2015-12-03
WO2015181055A1 (en) 2015-12-03
UY36152A (en) 2016-01-08
CN106414449A (en) 2017-02-15
CL2016002971A1 (en) 2017-02-17
CR20160538A (en) 2017-01-02
EP3148585A1 (en) 2017-04-05
TW201625260A (en) 2016-07-16
US20170158699A1 (en) 2017-06-08
JP2017516797A (en) 2017-06-22
MX2016014904A (en) 2017-02-28
SG11201607950SA (en) 2016-10-28
PH12016502256A1 (en) 2017-02-06
EA201692435A1 (en) 2017-04-28
MD20160132A2 (en) 2017-05-31
EA201692436A1 (en) 2017-04-28
MD20160138A2 (en) 2017-05-31
KR20170012236A (en) 2017-02-02
PE20170145A1 (en) 2017-03-10
EP3148586A1 (en) 2017-04-05
TW201625258A (en) 2016-07-16
CL2016002970A1 (en) 2017-02-10
IL247073D0 (en) 2016-09-29
IL247072D0 (en) 2016-09-29
EP3148999A1 (en) 2017-04-05
CA2941429A1 (en) 2015-12-03
IL247901D0 (en) 2016-11-30
EA201692437A1 (en) 2017-04-28
UY36153A (en) 2016-01-08
KR20170007760A (en) 2017-01-20
UY36151A (en) 2016-01-08
CN106456777A (en) 2017-02-22

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