SG11201605956RA - Cholesteryl ester transfer protein (cetp) inhibitor and pharmaceutical compositions comprising said inhibitor for use in the treatment or prevention of cardiovascular diseases - Google Patents

Cholesteryl ester transfer protein (cetp) inhibitor and pharmaceutical compositions comprising said inhibitor for use in the treatment or prevention of cardiovascular diseases

Info

Publication number
SG11201605956RA
SG11201605956RA SG11201605956RA SG11201605956RA SG11201605956RA SG 11201605956R A SG11201605956R A SG 11201605956RA SG 11201605956R A SG11201605956R A SG 11201605956RA SG 11201605956R A SG11201605956R A SG 11201605956RA SG 11201605956R A SG11201605956R A SG 11201605956RA
Authority
SG
Singapore
Prior art keywords
inhibitor
cetp
prevention
treatment
pharmaceutical compositions
Prior art date
Application number
SG11201605956RA
Inventor
John Ford
Patrick Round
John Kastelein
Atsuhiro Kawaguchi
Koichi Tomiyasu
Kozo Oka
Original Assignee
Dezima Pharma B V
Mitsubishi Tanabe Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dezima Pharma B V, Mitsubishi Tanabe Pharma Corp filed Critical Dezima Pharma B V
Publication of SG11201605956RA publication Critical patent/SG11201605956RA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/472Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SG11201605956RA 2014-02-05 2014-02-05 Cholesteryl ester transfer protein (cetp) inhibitor and pharmaceutical compositions comprising said inhibitor for use in the treatment or prevention of cardiovascular diseases SG11201605956RA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/NL2014/050068 WO2015119495A1 (en) 2014-02-05 2014-02-05 Cholesteryl ester transfer protein (cetp) inhibitor and pharmaceutical compositions comprising said inhibitor for use in the treatment or prevention of cardiovascular diseases

Publications (1)

Publication Number Publication Date
SG11201605956RA true SG11201605956RA (en) 2016-08-30

Family

ID=50116144

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201605956RA SG11201605956RA (en) 2014-02-05 2014-02-05 Cholesteryl ester transfer protein (cetp) inhibitor and pharmaceutical compositions comprising said inhibitor for use in the treatment or prevention of cardiovascular diseases

Country Status (32)

Country Link
US (4) US10653692B2 (en)
EP (1) EP3102212B1 (en)
JP (1) JP6263271B2 (en)
KR (1) KR101967970B1 (en)
CN (5) CN113332287A (en)
AP (1) AP2016009359A0 (en)
AR (1) AR099299A1 (en)
AU (1) AU2014381733B2 (en)
BR (1) BR112016018077A8 (en)
CA (1) CA2938718C (en)
CR (1) CR20160353A (en)
CY (1) CY1121707T1 (en)
DK (1) DK3102212T3 (en)
EA (1) EA032689B1 (en)
ES (1) ES2710104T3 (en)
HR (1) HRP20190211T1 (en)
HU (1) HUE042932T2 (en)
IL (1) IL247037A (en)
LT (1) LT3102212T (en)
MA (1) MA39319A1 (en)
ME (1) ME03295B (en)
MX (1) MX369471B (en)
PH (1) PH12016501548A1 (en)
PL (1) PL3102212T3 (en)
PT (1) PT3102212T (en)
RS (1) RS58329B1 (en)
SG (1) SG11201605956RA (en)
SI (1) SI3102212T1 (en)
TW (1) TWI651086B (en)
UA (1) UA120922C2 (en)
WO (1) WO2015119495A1 (en)
ZA (1) ZA201605490B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI3102212T1 (en) 2014-02-05 2019-03-29 Dezima Pharma B.V. Cholesteryl ester transfer protein (cetp) inhibitor and pharmaceutical compositions comprising said inhibitor for use in the treatment or prevention of cardiovascular diseases
EP4218765A3 (en) * 2014-08-28 2023-08-09 NewAmsterdam Pharma B.V. Pharmaceutical composition and therapeutic combination comprising a cholesteryl ester transfer protein inhibitor and hmg coa reductase inhibitors
CA3210033A1 (en) * 2021-02-18 2022-08-25 Newamsterdam Pharma B.V. Combination therapy of obicetrapib and ezetimibe for use in statin intolerant patients suffering from hyperlipidemia or mixed dyslipidaemia
IL305576A (en) * 2021-03-05 2023-10-01 Newamsterdam Pharma B V Obicetrapib for treatment of dementias
WO2024009144A1 (en) 2022-07-05 2024-01-11 Newamsterdam Pharma B.V. Salts of obicetrapib and processes for their manufacture and intermediates thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA90269C2 (en) * 2004-04-02 2010-04-26 Мицубиси Танабе Фарма Корпорейшн Tetrahydroquinoline derivatives and a process for preparing the same
KR20070041452A (en) * 2004-06-24 2007-04-18 일라이 릴리 앤드 캄파니 Compounds and methods for treating dyslipidemia
CN101098690A (en) * 2004-12-06 2008-01-02 瑞莱恩特医药品有限公司 Omega-3 fatty acids and dyslipidemic agent for lipid therapy
JP4531027B2 (en) * 2005-09-29 2010-08-25 田辺三菱製薬株式会社 Pharmaceutical composition
EA018734B1 (en) * 2006-10-10 2013-10-30 Релайэнт Фармасьютикалз, Инк. STATIN AND OMEGA-3 FATTY ACIDS FOR REDUCTION OF Apo-B LEVELS
JO3210B1 (en) 2011-10-28 2018-03-08 Merck Sharp & Dohme Fused bicyclic oxazolidinone cetp inhibitor
SI3102212T1 (en) 2014-02-05 2019-03-29 Dezima Pharma B.V. Cholesteryl ester transfer protein (cetp) inhibitor and pharmaceutical compositions comprising said inhibitor for use in the treatment or prevention of cardiovascular diseases
EP4218765A3 (en) * 2014-08-28 2023-08-09 NewAmsterdam Pharma B.V. Pharmaceutical composition and therapeutic combination comprising a cholesteryl ester transfer protein inhibitor and hmg coa reductase inhibitors

Also Published As

Publication number Publication date
CA2938718C (en) 2022-10-18
RS58329B1 (en) 2019-03-29
EA032689B1 (en) 2019-07-31
BR112016018077A8 (en) 2020-06-23
AU2014381733B2 (en) 2020-09-03
EA201691572A1 (en) 2016-12-30
KR101967970B1 (en) 2019-04-10
CN113332287A (en) 2021-09-03
KR20160146664A (en) 2016-12-21
US20240024315A1 (en) 2024-01-25
ES2710104T3 (en) 2019-04-23
MX2016010212A (en) 2017-08-10
CN112755031A (en) 2021-05-07
TW201613597A (en) 2016-04-16
ZA201605490B (en) 2018-05-30
AR099299A1 (en) 2016-07-13
US11013742B2 (en) 2021-05-25
UA120922C2 (en) 2020-03-10
WO2015119495A1 (en) 2015-08-13
US20210228580A1 (en) 2021-07-29
PT3102212T (en) 2019-02-06
EP3102212B1 (en) 2018-11-07
AP2016009359A0 (en) 2016-08-31
US11642344B2 (en) 2023-05-09
JP2017505333A (en) 2017-02-16
EP3102212A1 (en) 2016-12-14
HRP20190211T1 (en) 2019-04-05
MA39319A1 (en) 2017-07-31
CN106232121A (en) 2016-12-14
IL247037A (en) 2017-01-31
CN113332288A (en) 2021-09-03
DK3102212T3 (en) 2019-02-11
CN110721187A (en) 2020-01-24
PL3102212T3 (en) 2019-05-31
ME03295B (en) 2019-07-20
US20200230138A1 (en) 2020-07-23
US20170182048A1 (en) 2017-06-29
NZ723645A (en) 2020-09-25
AU2014381733A1 (en) 2016-08-18
US10653692B2 (en) 2020-05-19
CY1121707T1 (en) 2020-07-31
MX369471B (en) 2019-11-08
SI3102212T1 (en) 2019-03-29
CA2938718A1 (en) 2015-08-13
BR112016018077A2 (en) 2017-08-08
LT3102212T (en) 2019-02-25
PH12016501548B1 (en) 2016-10-03
HUE042932T2 (en) 2019-07-29
PH12016501548A1 (en) 2016-10-03
JP6263271B2 (en) 2018-01-17
CR20160353A (en) 2017-06-23
TWI651086B (en) 2019-02-21

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