SG11201600777WA - Method for producing dopaminergic neurons - Google Patents
Method for producing dopaminergic neuronsInfo
- Publication number
- SG11201600777WA SG11201600777WA SG11201600777WA SG11201600777WA SG11201600777WA SG 11201600777W A SG11201600777W A SG 11201600777WA SG 11201600777W A SG11201600777W A SG 11201600777WA SG 11201600777W A SG11201600777W A SG 11201600777WA SG 11201600777W A SG11201600777W A SG 11201600777WA
- Authority
- SG
- Singapore
- Prior art keywords
- dopaminergic neurons
- producing dopaminergic
- producing
- neurons
- dopaminergic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0619—Neurons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/38—Vitamins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/01—Modulators of cAMP or cGMP, e.g. non-hydrolysable analogs, phosphodiesterase inhibitors, cholera toxin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/16—Activin; Inhibin; Mullerian inhibiting substance
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/72—Transferases (EC 2.)
- C12N2501/727—Kinases (EC 2.7.)
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Developmental Biology & Embryology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Immunology (AREA)
- Ophthalmology & Optometry (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Alternative & Traditional Medicine (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013163062 | 2013-08-06 | ||
| PCT/JP2014/071352 WO2015020234A1 (en) | 2013-08-06 | 2014-08-06 | Method for producing dopaminergic neurons |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201600777WA true SG11201600777WA (en) | 2016-03-30 |
Family
ID=52461553
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201600777WA SG11201600777WA (en) | 2013-08-06 | 2014-08-06 | Method for producing dopaminergic neurons |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US10017734B2 (en) |
| EP (1) | EP3031908B1 (en) |
| JP (1) | JP6419073B2 (en) |
| KR (1) | KR102215373B1 (en) |
| CN (1) | CN105658788B (en) |
| AU (1) | AU2014303330B2 (en) |
| CA (1) | CA2920287C (en) |
| ES (1) | ES2712878T3 (en) |
| NZ (1) | NZ716812A (en) |
| SG (1) | SG11201600777WA (en) |
| WO (1) | WO2015020234A1 (en) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10179132B2 (en) * | 2015-05-26 | 2019-01-15 | Industry-Academic Cooperation Foundation, Yonsei University | Composition for inducing differentiation of multipotent neural stem cells into dopaminergic neurons and method for inducing differentiation of multipotent neural stem cells into dopaminergic neurons by using the same |
| HUE058258T2 (en) * | 2015-06-01 | 2022-07-28 | Memorial Sloan Kettering Cancer Center | Methods of in vitro differentiation of midbrain dopamine (mda) neurons |
| US20180057788A1 (en) * | 2016-08-29 | 2018-03-01 | EMULATE, Inc. | Development of spinal cord on a microfluidic chip |
| WO2017136462A2 (en) | 2016-02-01 | 2017-08-10 | EMULATE, Inc. | Systems and methods for growth of intestinal cells in microfluidic devices |
| KR101870240B1 (en) * | 2016-04-12 | 2018-06-22 | 서울대학교산학협력단 | Differentiation method of adipose-derived mesenchymal stem cells into neural stem cells, neural cells, and GABAergic neural cells |
| CN109844102B (en) | 2016-08-16 | 2023-11-10 | 富士胶片细胞动力股份有限公司 | Method for differentiating pluripotent cells |
| DK3425390T3 (en) | 2016-11-25 | 2021-02-15 | Genuv Inc | Composition for promoting differentiation and protection of neural stem cells and method for inducing neural regeneration using them |
| WO2018140647A1 (en) | 2017-01-25 | 2018-08-02 | Cedars-Sinai Medical Center | In vitro induction of mammary-like differentiation from human pluripotent stem cells |
| US11767513B2 (en) | 2017-03-14 | 2023-09-26 | Cedars-Sinai Medical Center | Neuromuscular junction |
| WO2018176001A2 (en) | 2017-03-24 | 2018-09-27 | Cedars-Sinai Medical Center | Methods and compositions for production of fallopian tube epithelium |
| EP3613848A4 (en) | 2017-04-19 | 2021-01-20 | National University Corporation Nagoya University | Method for producing dopaminergic neurons |
| KR101862548B1 (en) * | 2017-07-24 | 2018-05-30 | 연세대학교 산학협력단 | composition for inducing differentiation of multi-potent neural stem cell into dopaminergic meurons and method for inducing differentiation using the same |
| KR101833412B1 (en) * | 2017-07-24 | 2018-02-28 | 연세대학교 산학협력단 | composition for inducing differentiation of multi-potent neural stem cell into dopaminergic meurons and method for inducing differentiation using the same |
| JP2019106895A (en) * | 2017-12-15 | 2019-07-04 | インダストリー‐ユニバーシティー コーぺレーション ファンデーション ハンヤン ユニバーシティ | Method of differentiating neural stem cells or neural precursor cells into dopamine neurons |
| KR102206657B1 (en) * | 2017-12-15 | 2021-01-22 | 한양대학교 산학협력단 | Method for differentiation of dopamine neurons from neural stem cells or neural precursor cells and use thereof |
| CN108359638B (en) * | 2018-04-04 | 2020-02-14 | 浙江霍德生物工程有限公司 | Method for inducing differentiation of functional cerebral cortex cells |
| WO2019195800A1 (en) | 2018-04-06 | 2019-10-10 | Cedars-Sinai Medical Center | Novel differentiation technique to generate dopaminergic neurons from induced pluripotent stem cells |
| US11130937B2 (en) * | 2018-05-24 | 2021-09-28 | The Board Of Regents Of The University Of Texas System | Compositions and methods for long-term in vitro culture of the syphilis spirochete |
| WO2020204149A1 (en) | 2019-03-29 | 2020-10-08 | 公立大学法人横浜市立大学 | Screening method and toxicity evaluation method |
| US20230242874A1 (en) * | 2020-06-26 | 2023-08-03 | Minerva Biotechnologies Corporation | Methods for deriving dopaminergic neurons from pluripotent stem cells |
| CN115916240A (en) * | 2020-08-17 | 2023-04-04 | 中国科学院动物研究所 | Amplification culture medium and culture method of neural cells |
| KR20230165846A (en) | 2021-04-07 | 2023-12-05 | 후지필름 셀룰러 다이내믹스, 인코포레이티드 | Dopaminergic progenitor cells and methods of use |
| AU2022313776A1 (en) * | 2021-07-19 | 2024-01-25 | Trailhead Biosystems Inc. | Methods and compositions for generating human midbrain neural progenitor cells |
| CN115521903B (en) * | 2022-09-30 | 2024-05-17 | 中国科学院生态环境研究中心 | Method for in vitro induction of differentiation of human pluripotent stem cells into dopaminergic neurons |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7250294B2 (en) * | 2000-05-17 | 2007-07-31 | Geron Corporation | Screening small molecule drugs using neural cells differentiated from human embryonic stem cells |
| AU2003296316A1 (en) * | 2002-12-09 | 2004-06-30 | The Mclean Hospital Corporation | Dopaminergic neurons differentiated from embryonic cells for treating neurodegenerative diseases |
| RU2345133C2 (en) * | 2003-03-12 | 2009-01-27 | Релайанс Лайф Сайенсиз Пвт. Лтд. | Production of terminal-differentiated dofaminnergic neurones from embrionic human founder cells |
| DE102004028899B4 (en) * | 2004-06-09 | 2009-09-03 | Technische Universität Dresden | Use of a combination for the preventive and / or therapeutic treatment of bacterial infectious diseases or sepsis |
| JP2008511304A (en) * | 2004-09-02 | 2008-04-17 | ニューロ セラピューティクス エービー | Methods and materials for enhanced production of dopamine neurons |
| KR100952200B1 (en) * | 2007-10-31 | 2010-04-09 | 한양대학교 산학협력단 | Method for expanding neural precursors and generating dopamine neurons using the expanded neural precursors |
| US8642334B2 (en) | 2009-02-17 | 2014-02-04 | Memorial Sloan Kettering Cancer Center | Methods of neural conversion of human embryonic stem cells |
| WO2010108008A2 (en) * | 2009-03-18 | 2010-09-23 | University Of Georgia Research Foundation | Bsc cell differentiation and use in therapy |
| US20130108669A1 (en) | 2010-04-16 | 2013-05-02 | The Mclean Hospital Corporation | Dopaminergic neurons differentiated from pluripotent stem cells and uses of thereof |
| KR101106020B1 (en) * | 2010-06-14 | 2012-01-17 | 차의과학대학교 산학협력단 | Process for differentiation of human neural progenitor cells to dopaminergic neurons and medium for differentiation thereof |
| PT2773748T (en) | 2011-11-04 | 2020-03-26 | Memorial Sloan Kettering Cancer Center | Midbrain dopamine (da) neurons for engraftment |
| WO2013187416A1 (en) | 2012-06-12 | 2013-12-19 | 学校法人 慶應義塾 | METHOD FOR AMPLIFYING iPS CELL SUITABLE FOR NEURAL DIFFERENTIATION, AND METHOD FOR INDUCING NEURAL STEM CELL |
| JP2016517266A (en) * | 2013-02-18 | 2016-06-16 | ユニバーシティー ヘルス ネットワーク | Method for producing hepatocytes and bile duct cells from pluripotent stem cells |
| JP5637256B2 (en) | 2013-05-23 | 2014-12-10 | 株式会社三洋物産 | Game machine |
-
2014
- 2014-08-06 US US14/910,018 patent/US10017734B2/en active Active
- 2014-08-06 CN CN201480044581.7A patent/CN105658788B/en active Active
- 2014-08-06 JP JP2015530994A patent/JP6419073B2/en active Active
- 2014-08-06 WO PCT/JP2014/071352 patent/WO2015020234A1/en active Application Filing
- 2014-08-06 CA CA2920287A patent/CA2920287C/en active Active
- 2014-08-06 NZ NZ716812A patent/NZ716812A/en unknown
- 2014-08-06 AU AU2014303330A patent/AU2014303330B2/en active Active
- 2014-08-06 SG SG11201600777WA patent/SG11201600777WA/en unknown
- 2014-08-06 EP EP14834874.1A patent/EP3031908B1/en active Active
- 2014-08-06 ES ES14834874T patent/ES2712878T3/en active Active
- 2014-08-06 KR KR1020167005862A patent/KR102215373B1/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| CN105658788A (en) | 2016-06-08 |
| EP3031908B1 (en) | 2018-12-05 |
| JP6419073B2 (en) | 2018-11-07 |
| KR20160040286A (en) | 2016-04-12 |
| US10017734B2 (en) | 2018-07-10 |
| AU2014303330A1 (en) | 2016-03-10 |
| AU2014303330B2 (en) | 2020-08-27 |
| EP3031908A4 (en) | 2016-12-21 |
| JPWO2015020234A1 (en) | 2017-03-02 |
| EP3031908A1 (en) | 2016-06-15 |
| NZ716812A (en) | 2022-04-29 |
| CA2920287C (en) | 2022-03-08 |
| ES2712878T3 (en) | 2019-05-16 |
| WO2015020234A1 (en) | 2015-02-12 |
| CN105658788B (en) | 2020-07-10 |
| KR102215373B1 (en) | 2021-02-10 |
| CA2920287A1 (en) | 2015-02-12 |
| US20160177260A1 (en) | 2016-06-23 |
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