SG11201600455XA - Instantly wettable oral film dosage form without surfactant or polyalcohol - Google Patents

Instantly wettable oral film dosage form without surfactant or polyalcohol

Info

Publication number
SG11201600455XA
SG11201600455XA SG11201600455XA SG11201600455XA SG11201600455XA SG 11201600455X A SG11201600455X A SG 11201600455XA SG 11201600455X A SG11201600455X A SG 11201600455XA SG 11201600455X A SG11201600455X A SG 11201600455XA SG 11201600455X A SG11201600455X A SG 11201600455XA
Authority
SG
Singapore
Prior art keywords
polyalcohol
surfactant
dosage form
oral film
film dosage
Prior art date
Application number
SG11201600455XA
Inventor
Horst G Zerbe
Angela Angusti
Nadine Paiement
Original Assignee
Intelgenx Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52428223&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201600455X(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Intelgenx Corp filed Critical Intelgenx Corp
Publication of SG11201600455XA publication Critical patent/SG11201600455XA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41961,2,4-Triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/422Oxazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/473Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/55171,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
SG11201600455XA 2013-07-31 2014-07-30 Instantly wettable oral film dosage form without surfactant or polyalcohol SG11201600455XA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361860345P 2013-07-31 2013-07-31
PCT/IB2014/002047 WO2015015303A2 (en) 2013-07-31 2014-07-30 Instantly wettable oral film dosage form without surfactant or polyalcohol

Publications (1)

Publication Number Publication Date
SG11201600455XA true SG11201600455XA (en) 2016-02-26

Family

ID=52428223

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201600455XA SG11201600455XA (en) 2013-07-31 2014-07-30 Instantly wettable oral film dosage form without surfactant or polyalcohol

Country Status (18)

Country Link
US (1) US9301948B2 (en)
EP (2) EP3027179B1 (en)
JP (1) JP6482552B2 (en)
KR (1) KR102272442B1 (en)
CN (1) CN105530921B (en)
AU (1) AU2014298130A1 (en)
BR (1) BR112016002074B1 (en)
CA (1) CA2919442A1 (en)
CL (1) CL2016000160A1 (en)
DK (1) DK3027179T3 (en)
ES (1) ES2706481T3 (en)
HK (1) HK1222796A1 (en)
IL (1) IL243651A0 (en)
MX (1) MX366595B (en)
RU (1) RU2016106907A (en)
SG (1) SG11201600455XA (en)
WO (1) WO2015015303A2 (en)
ZA (1) ZA201600785B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160220480A1 (en) * 2015-02-03 2016-08-04 Intelgenx Corp. Oral dosage film exhibiting enhanced mucosal penetration
CN105997955B (en) 2016-06-28 2017-09-12 力品药业(厦门)有限公司 A kind of Palonosetron oral cavity membrane and preparation method thereof
KR101802183B1 (en) * 2016-11-16 2017-11-28 주식회사 유영제약 Pharmaceutical compositions comprising palonosetron as active ingredient
DE102017127452A1 (en) * 2017-11-21 2019-05-23 Lts Lohmann Therapie-Systeme Ag Water-soluble polymer adhesive layers

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19646392A1 (en) 1996-11-11 1998-05-14 Lohmann Therapie Syst Lts Preparation for use in the oral cavity with a layer containing pressure-sensitive adhesive, pharmaceuticals or cosmetics for dosed delivery
JP3460538B2 (en) * 1997-10-08 2003-10-27 救急薬品工業株式会社 Fast dissolving film preparation
US7027414B2 (en) * 2001-08-09 2006-04-11 Hughes Network Systems, Llc Method, apparatus, and system for identifying and efficiently treating classes of traffic
DK1695094T3 (en) 2003-10-24 2013-09-16 Adhesives Res Inc Disintegrating films for diagnostic devices
AU2005210637B2 (en) * 2004-01-30 2010-09-16 A.V. Topchiev Institute Of Petrochemical Synthesis Rapidly dissolving film for delivery of an active agent
US20050281757A1 (en) * 2004-06-17 2005-12-22 Sayed Ibrahim Oral care film
CN101896172A (en) * 2007-12-11 2010-11-24 诺瓦提斯公司 Multi-zone films
CA2737307A1 (en) * 2008-10-14 2010-04-22 Mcneil Ab Multi portion intra-oral dosage form and use thereof
US8715715B2 (en) * 2008-11-03 2014-05-06 Nal Pharmaceuticals Ltd. Dosage form for insertion into the mouth
US20100285130A1 (en) * 2009-05-06 2010-11-11 Monosol Rx, Llc Coating of complexed actives in film formulations
CN102665762A (en) * 2009-11-24 2012-09-12 巴斯夫欧洲公司 Film-like pharmaceutical dosage forms
US20110136815A1 (en) 2009-12-08 2011-06-09 Horst Zerbe Solid oral film dosage forms and methods for making same
US20110263606A1 (en) * 2010-04-26 2011-10-27 Horst Zerbe Solid oral dosage forms comprising tadalafil
JP2012031164A (en) * 2010-07-06 2012-02-16 Teika Seiyaku Kk Film-shaped preparation
JP5587168B2 (en) * 2010-12-28 2014-09-10 花王株式会社 Cleaning composition for medical equipment
US20120282191A1 (en) * 2011-01-17 2012-11-08 Takeda Pharmaceutical Company Limited Orally dispersible tablet
KR101303479B1 (en) * 2011-07-28 2013-09-06 (주)씨엘팜 Composition for edible film and pharmaceutical preparation for edible film containing drugs
MX370064B (en) * 2013-05-10 2019-11-29 Ctc Bio Inc Film preparation containing donepezil-free base and method for producing same.

Also Published As

Publication number Publication date
JP2016527262A (en) 2016-09-08
CA2919442A1 (en) 2015-02-05
WO2015015303A2 (en) 2015-02-05
CN105530921A (en) 2016-04-27
ZA201600785B (en) 2017-04-26
CL2016000160A1 (en) 2016-11-18
DK3027179T3 (en) 2019-02-11
AU2014298130A1 (en) 2016-02-11
MX366595B (en) 2019-07-15
EP3027179A2 (en) 2016-06-08
IL243651A0 (en) 2016-02-29
RU2016106907A (en) 2017-09-01
EP3027179B1 (en) 2018-10-17
BR112016002074B1 (en) 2023-01-24
MX2016001399A (en) 2016-10-28
US20150038540A1 (en) 2015-02-05
ES2706481T3 (en) 2019-03-29
WO2015015303A3 (en) 2015-05-21
BR112016002074A2 (en) 2017-08-01
KR102272442B1 (en) 2021-07-02
HK1222796A1 (en) 2017-07-14
EP3027179A4 (en) 2017-02-22
JP6482552B2 (en) 2019-03-13
CN105530921B (en) 2021-02-26
US9301948B2 (en) 2016-04-05
KR20160089335A (en) 2016-07-27
EP3427732A1 (en) 2019-01-16

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