SG11201508054UA - Combretastatin analogs - Google Patents
Combretastatin analogsInfo
- Publication number
- SG11201508054UA SG11201508054UA SG11201508054UA SG11201508054UA SG11201508054UA SG 11201508054U A SG11201508054U A SG 11201508054UA SG 11201508054U A SG11201508054U A SG 11201508054UA SG 11201508054U A SG11201508054U A SG 11201508054UA SG 11201508054U A SG11201508054U A SG 11201508054UA
- Authority
- SG
- Singapore
- Prior art keywords
- combretastatin analogs
- combretastatin
- analogs
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Furan Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361814028P | 2013-04-19 | 2013-04-19 | |
| US201361866878P | 2013-08-16 | 2013-08-16 | |
| US201361901710P | 2013-11-08 | 2013-11-08 | |
| PCT/US2014/034185 WO2014172363A2 (en) | 2013-04-19 | 2014-04-15 | Combretastatin analogs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201508054UA true SG11201508054UA (en) | 2015-11-27 |
Family
ID=51731968
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201508054UA SG11201508054UA (en) | 2013-04-19 | 2014-04-15 | Combretastatin analogs |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US9884842B2 (en) |
| EP (1) | EP2986596A4 (en) |
| JP (1) | JP2016516814A (en) |
| AU (1) | AU2014254078A1 (en) |
| BR (1) | BR112015026048A2 (en) |
| CA (1) | CA2907853A1 (en) |
| MX (1) | MX2015014470A (en) |
| SG (1) | SG11201508054UA (en) |
| WO (1) | WO2014172363A2 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016504366A (en) | 2012-12-28 | 2016-02-12 | ザ ボード オブ トラスティーズ オブ ザ ユニバーシティ オブ アーカンソー | Indole compounds used in the treatment of inflammation and cancer |
| MX2015014470A (en) | 2013-04-19 | 2016-02-22 | Univ Arkansas | Combretastatin analogs. |
| EP3125886A4 (en) | 2014-03-31 | 2017-09-06 | Bioventures, Llc | Disubstituted triazole analogs |
| US10800766B2 (en) * | 2015-11-28 | 2020-10-13 | Russell Dahl | Quinoline alkenes as cytoprotective agents |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH522432A (en) | 1967-02-07 | 1972-06-30 | Ciba Geigy Ag | 2-substituted v-triazoles as ultraviolet stabilisers |
| DE1944419A1 (en) | 1969-09-02 | 1971-03-11 | Thiemann Gmbh Chem Pharm Fabri | Antiphlogistic 2-methyl-indole derivs |
| DE3410700A1 (en) | 1984-03-23 | 1985-09-26 | Basf Ag, 6700 Ludwigshafen | 2,4,5-TRIPHENYL-V-TRIAZOLES AND THEIR USE |
| GB9019841D0 (en) | 1990-09-11 | 1990-10-24 | Smith Kline French Lab | Compounds |
| US5972976A (en) | 1994-04-06 | 1999-10-26 | Nippon Shinyaku Company, Limited | Aminostilbazole derivative and medicine |
| US5484940A (en) | 1994-11-28 | 1996-01-16 | Grant; Francine S. | Substituted 3-indolyl-5-pyrazolone compounds |
| AU2190700A (en) * | 1998-12-17 | 2000-07-03 | Tularik Inc. | Tubulin-binding agents |
| WO2003018008A1 (en) | 2000-02-25 | 2003-03-06 | Shionogi & Co., Ltd. | Apo ai expression accelerating agent |
| GB0013655D0 (en) | 2000-06-05 | 2000-07-26 | Prolifix Ltd | Therapeutic compounds |
| GB0127433D0 (en) | 2001-11-15 | 2002-01-09 | Smithkline Beecham Corp | Compounds |
| CA2602467C (en) * | 2005-03-30 | 2014-09-02 | Kabushiki Kaisha Yakult Honsha | Bcrp/abcg2 inhibitor |
| JP5149177B2 (en) | 2005-07-25 | 2013-02-20 | シンタ ファーマシューティカルズ コーポレーション | Tubulin polymerized 1,2,3-triazole inhibitors for the treatment of proliferative diseases |
| US8980954B2 (en) | 2006-04-25 | 2015-03-17 | Stc.Unm | Substituted cis- and trans-stilbenes as therapeutic agents |
| EP1921072A1 (en) | 2006-11-10 | 2008-05-14 | Laboratorios del Dr. Esteve S.A. | 1,2,3-Triazole derivatives as cannabinoid-receptor modulators |
| US7781580B2 (en) * | 2007-04-23 | 2010-08-24 | Virginia Commonwealth University | Stilbene derivatives as new cancer therapeutic agents |
| WO2009023773A2 (en) | 2007-08-15 | 2009-02-19 | University Of Miami | Galactokinase inhibitors |
| CN101932325B (en) | 2007-11-30 | 2014-05-28 | 新联基因公司 | Ido inhibitors |
| WO2009151920A2 (en) | 2008-06-11 | 2009-12-17 | Fred Hutchinson Cancer Research Center | Hepsin inhibitors |
| US8304421B2 (en) | 2008-09-30 | 2012-11-06 | Vanderbilt University | Indole compounds and their use as radiation sensitizing agents and chemotherapeutic agents |
| TW201021797A (en) | 2008-12-04 | 2010-06-16 | Nat Univ Tsing Hua | 1,2,3-triazole derivatives as new cannabinoid-1 receptor antagonists |
| EP2266562A1 (en) | 2009-06-23 | 2010-12-29 | Centre National de la Recherche Scientifique | Use of derivatives of indoles for the treatment of cancer |
| WO2010151799A2 (en) * | 2009-06-26 | 2010-12-29 | University Of Massachusetts | Compounds for modulating rna binding proteins and uses therefor |
| JP2013533846A (en) | 2010-04-06 | 2013-08-29 | ブリガム・ヤング・ユニバーシティ | Anti-metastatic compound |
| JP5786402B2 (en) * | 2011-03-29 | 2015-09-30 | コニカミノルタ株式会社 | Optical film, polarizing plate using the same, and liquid crystal display device |
| JP2016504366A (en) | 2012-12-28 | 2016-02-12 | ザ ボード オブ トラスティーズ オブ ザ ユニバーシティ オブ アーカンソー | Indole compounds used in the treatment of inflammation and cancer |
| MX2015014470A (en) | 2013-04-19 | 2016-02-22 | Univ Arkansas | Combretastatin analogs. |
| WO2014176351A1 (en) | 2013-04-23 | 2014-10-30 | The Board Of Trustees Of The University Of Arkansas | Polymerase, endonuclease, and helicase inhibitors and methods of using thereof |
| DK3016666T3 (en) | 2013-06-13 | 2019-07-01 | Smartfish As | Fish oil formulation comprising reservatrol or derivatives thereof for use in treating, delaying and / or preventing Alzheimer's disease |
| EP3125886A4 (en) | 2014-03-31 | 2017-09-06 | Bioventures, Llc | Disubstituted triazole analogs |
| WO2018144910A1 (en) | 2017-02-02 | 2018-08-09 | Bioventures, Llc | Methods of protecting against neurodegeneration |
-
2014
- 2014-04-15 MX MX2015014470A patent/MX2015014470A/en unknown
- 2014-04-15 AU AU2014254078A patent/AU2014254078A1/en not_active Abandoned
- 2014-04-15 CA CA2907853A patent/CA2907853A1/en not_active Abandoned
- 2014-04-15 BR BR112015026048A patent/BR112015026048A2/en not_active IP Right Cessation
- 2014-04-15 EP EP14785256.0A patent/EP2986596A4/en not_active Withdrawn
- 2014-04-15 US US14/785,381 patent/US9884842B2/en not_active Expired - Fee Related
- 2014-04-15 WO PCT/US2014/034185 patent/WO2014172363A2/en active Application Filing
- 2014-04-15 SG SG11201508054UA patent/SG11201508054UA/en unknown
- 2014-04-15 JP JP2016509030A patent/JP2016516814A/en active Pending
-
2017
- 2017-12-20 US US15/849,150 patent/US10100029B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| BR112015026048A2 (en) | 2017-07-25 |
| EP2986596A2 (en) | 2016-02-24 |
| WO2014172363A3 (en) | 2014-12-31 |
| US20160068506A1 (en) | 2016-03-10 |
| US9884842B2 (en) | 2018-02-06 |
| US10100029B2 (en) | 2018-10-16 |
| CA2907853A1 (en) | 2014-10-23 |
| WO2014172363A2 (en) | 2014-10-23 |
| MX2015014470A (en) | 2016-02-22 |
| AU2014254078A1 (en) | 2015-10-15 |
| EP2986596A4 (en) | 2017-02-08 |
| US20180118710A1 (en) | 2018-05-03 |
| JP2016516814A (en) | 2016-06-09 |
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