SG11201505201TA - Protein purification in the presence of nonionic organic polymers at elevated conductivity - Google Patents

Protein purification in the presence of nonionic organic polymers at elevated conductivity

Info

Publication number
SG11201505201TA
SG11201505201TA SG11201505201TA SG11201505201TA SG11201505201TA SG 11201505201T A SG11201505201T A SG 11201505201TA SG 11201505201T A SG11201505201T A SG 11201505201TA SG 11201505201T A SG11201505201T A SG 11201505201TA SG 11201505201T A SG11201505201T A SG 11201505201TA
Authority
SG
Singapore
Prior art keywords
protein purification
organic polymers
nonionic organic
elevated conductivity
elevated
Prior art date
Application number
SG11201505201TA
Inventor
Peter Stanley Gagnon
Original Assignee
Agency Science Tech & Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency Science Tech & Res filed Critical Agency Science Tech & Res
Publication of SG11201505201TA publication Critical patent/SG11201505201TA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/30Extraction; Separation; Purification by precipitation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065Purification, fragmentation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Chemical Kinetics & Catalysis (AREA)
SG11201505201TA 2013-02-28 2014-02-27 Protein purification in the presence of nonionic organic polymers at elevated conductivity SG11201505201TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361770890P 2013-02-28 2013-02-28
PCT/SG2014/000089 WO2014133460A1 (en) 2013-02-28 2014-02-27 Protein purification in the presence of nonionic organic polymers at elevated conductivity

Publications (1)

Publication Number Publication Date
SG11201505201TA true SG11201505201TA (en) 2015-08-28

Family

ID=51428598

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201505201TA SG11201505201TA (en) 2013-02-28 2014-02-27 Protein purification in the presence of nonionic organic polymers at elevated conductivity

Country Status (7)

Country Link
US (1) US10253063B2 (en)
EP (1) EP2961761B1 (en)
JP (1) JP2016509069A (en)
KR (1) KR20150122650A (en)
CN (1) CN105008384A (en)
SG (1) SG11201505201TA (en)
WO (1) WO2014133460A1 (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2902799B1 (en) 2006-06-27 2012-10-26 Millipore Corp METHOD AND UNIT FOR PREPARING A SAMPLE FOR THE MICROBIOLOGICAL ANALYSIS OF A LIQUID
WO2008079280A1 (en) 2006-12-21 2008-07-03 Millipore Corporation Purification of proteins
US8569464B2 (en) 2006-12-21 2013-10-29 Emd Millipore Corporation Purification of proteins
US8362217B2 (en) 2006-12-21 2013-01-29 Emd Millipore Corporation Purification of proteins
US20100190963A1 (en) 2008-12-16 2010-07-29 Millipore Corporation Stirred Tank Reactor And Method
BR112012028977B1 (en) 2010-05-17 2020-05-05 Emd Millipore Corp biomolecule purification method by means of stimulus-responsive polymers
EP2961759A4 (en) * 2013-02-26 2016-09-28 Agency Science Tech & Res Protein purification in the presence of nonionic organic polymers and electropositive surfaces
CA2910065C (en) 2013-05-15 2023-09-19 Medimmune Limited Purification of recombinantly produced polypeptides
DE102016010601B4 (en) 2016-09-01 2018-11-08 Sartorius Stedim Biotech Gmbh A process for the purification of viruses or virus-like particles using a crosslinked cellulose hydrate membrane
US10400491B2 (en) * 2017-03-14 2019-09-03 Whirlpool Corporation Hinge cover with door stop
CN109574296B (en) * 2018-11-27 2021-05-07 合肥工业大学 Method for recovering protein from crab meat protein-containing wastewater
EP4321521A1 (en) * 2022-08-11 2024-02-14 PreOmics GmbH Fractionation of proteins for proteomics
WO2024033534A1 (en) 2022-08-11 2024-02-15 Preomics Gmbh Fractionation of proteins for proteomics

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US4814098A (en) 1986-09-06 1989-03-21 Bellex Corporation Magnetic material-physiologically active substance conjugate
JP2534849B2 (en) 1986-09-06 1996-09-18 タイホー工業株式会社 Magnetic substance bioactive substance complex
ATE122054T1 (en) * 1990-03-22 1995-05-15 Biotest Pharma Gmbh METHOD FOR PRODUCING AN INTRAVENOUSLY TOLERABLE IMMUNOGLOBULIN G PREPARATION.
AUPN858596A0 (en) * 1996-03-08 1996-04-04 Csl Limited Filtration of plasma precipitates using cellulose filter aid
NZ540895A (en) 2003-01-09 2007-03-30 Genentech Inc Purification of polypeptides with ethacridine lactate
MXPA06008435A (en) 2004-01-30 2007-05-23 Suomen Punainen Risti Veripalvelu Process for the manufacture of virus safe immunoglobulin.
JP2010534719A (en) * 2007-07-27 2010-11-11 ファイザー・リミテッド Antibody purification by precipitation
CA2720048A1 (en) * 2008-04-16 2009-10-22 Biogen Idec Ma Inc. Method of isolating biomacromolecules using polyalkylene glycol and transition metals
CA2726823A1 (en) 2008-06-03 2009-12-10 Patrys Limited Process for purification of antibodies
EP2350113A4 (en) * 2008-11-25 2013-01-02 Ge Healthcare Bio Sciences Ab Aqueous two phase extraction augmented precipitation process for purification of therapeutic proteins
EP2445925A1 (en) 2009-06-25 2012-05-02 Bristol-Myers Squibb Company Protein purification by caprylic acid (octanoic acid) precipitation
SG10201603931TA (en) * 2011-06-08 2016-07-28 Agency Science Tech & Res Purification Of Biological Products By Constrained Cohydration Chromatography
SG11201407801VA (en) * 2012-05-31 2014-12-30 Agency Science Tech & Res Methods for use of mixed multifunctional surfaces for reducing aggregate content in protein preparations
SG11201407812SA (en) * 2012-05-31 2014-12-30 Agency Science Tech & Res Methods for reducing levels of protein-contaminant complexes and aggregates in protein preparations by treatment with electropositive organic additives
JP6297029B2 (en) * 2012-05-31 2018-03-20 エイジェンシー・フォー・サイエンス,テクノロジー・アンド・リサーチ Chromatographic purification of immunoglobulin G preparations with particles having various functional groups
JP6200949B2 (en) * 2012-05-31 2017-09-20 エイジェンシー フォー サイエンス,テクノロジー アンド リサーチ Selective binding of biological targets to solid phase ureides
KR20150118103A (en) * 2013-02-06 2015-10-21 에이전시 포 사이언스, 테크놀로지 앤드 리서치 Protein purification methods
SG11201505460WA (en) * 2013-02-06 2015-08-28 Agency Science Tech & Res Methods for reducing aggregate levels in protein preparations by treatment with thio-heterocyclic cations
CN105121457B (en) * 2013-02-22 2019-04-30 新加坡科技研究局 For removing endotoxic material and method from protein formulation
EP2961759A4 (en) * 2013-02-26 2016-09-28 Agency Science Tech & Res Protein purification in the presence of nonionic organic polymers and electropositive surfaces
WO2014196926A1 (en) * 2013-06-04 2014-12-11 Agency For Science, Technology And Research Protein purification process
CN105980397A (en) * 2014-02-19 2016-09-28 新加坡科技研究局 Fractionation method
SG11201607098SA (en) * 2014-02-27 2016-09-29 Agency Science Tech & Res Antibody purification process
US10023609B2 (en) * 2014-02-27 2018-07-17 Agency For Science, Research And Technology Methods for reducing chromatin content in protein preparations by treatment with alkyl cations
CN106061993A (en) * 2014-02-27 2016-10-26 新加坡科技研究局 Methods for reducing aggregate content of protein preparations by treatment with aryl anions

Also Published As

Publication number Publication date
WO2014133460A1 (en) 2014-09-04
EP2961761A4 (en) 2016-11-02
US20160009758A1 (en) 2016-01-14
JP2016509069A (en) 2016-03-24
EP2961761A1 (en) 2016-01-06
EP2961761B1 (en) 2018-09-12
CN105008384A (en) 2015-10-28
KR20150122650A (en) 2015-11-02
US10253063B2 (en) 2019-04-09

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