SG11201504876TA - Methods and devices for analysis of defined multicellular combinations - Google Patents
Methods and devices for analysis of defined multicellular combinationsInfo
- Publication number
- SG11201504876TA SG11201504876TA SG11201504876TA SG11201504876TA SG11201504876TA SG 11201504876T A SG11201504876T A SG 11201504876TA SG 11201504876T A SG11201504876T A SG 11201504876TA SG 11201504876T A SG11201504876T A SG 11201504876TA SG 11201504876T A SG11201504876T A SG 11201504876TA
- Authority
- SG
- Singapore
- Prior art keywords
- combinations
- analysis
- methods
- devices
- multicellular
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/16—Microfluidic devices; Capillary tubes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/24—Gas permeable parts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
-
- G01N15/1023—
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N15/1484—Electro-optical investigation, e.g. flow cytometers microstructural devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5097—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving plant cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56961—Plant cells or fungi
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
- B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
- B01L2200/0652—Sorting or classification of particles or molecules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
- B01L2200/0668—Trapping microscopic beads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/10—Means to control humidity and/or other gases
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/12—Specific details about materials
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
-
- G01N2015/1028—
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361852135P | 2013-03-15 | 2013-03-15 | |
PCT/US2014/029344 WO2014144789A2 (en) | 2013-03-15 | 2014-03-14 | Methods and devices for analysis of defined multicellular combinations |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201504876TA true SG11201504876TA (en) | 2015-07-30 |
Family
ID=51538375
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201504876TA SG11201504876TA (en) | 2013-03-15 | 2014-03-14 | Methods and devices for analysis of defined multicellular combinations |
SG10201707485YA SG10201707485YA (en) | 2013-03-15 | 2014-03-14 | Methods and devices for analysis of defined multicellular combinations |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201707485YA SG10201707485YA (en) | 2013-03-15 | 2014-03-14 | Methods and devices for analysis of defined multicellular combinations |
Country Status (7)
Country | Link |
---|---|
US (2) | US10578633B2 (de) |
EP (2) | EP2970849B1 (de) |
JP (1) | JP2016521350A (de) |
CN (1) | CN105164246B (de) |
CA (1) | CA2895638A1 (de) |
SG (2) | SG11201504876TA (de) |
WO (1) | WO2014144789A2 (de) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010009365A1 (en) | 2008-07-18 | 2010-01-21 | Raindance Technologies, Inc. | Droplet libraries |
WO2015172080A1 (en) | 2014-05-08 | 2015-11-12 | Fluidigm Corporation | Integrated single cell sequencing |
EP3214426B1 (de) * | 2014-10-27 | 2024-03-27 | Universidade de Aveiro | Ausrüstung zur chromatischen diskriminierung und zählung von organismen |
WO2016094459A2 (en) | 2014-12-09 | 2016-06-16 | Berkeley Lights, Inc. | Automated detection and repositioning of micro-objects in microfluidic devices |
US10751715B1 (en) * | 2015-04-22 | 2020-08-25 | Berkeley Lights, Inc. | Microfluidic reporter cell assay methods and kits thereof |
CN114717183A (zh) | 2015-08-31 | 2022-07-08 | 爱平世股份有限公司 | 多能干细胞制造系统和生产诱导多能干细胞的方法 |
US20170160187A1 (en) * | 2015-12-08 | 2017-06-08 | Tdk Corporation | Laser Scanner Particle Counter and Imager |
US11285478B2 (en) | 2016-04-04 | 2022-03-29 | Combinati Incorporated | Microfluidic siphoning array for nucleic acid quantification |
JP7020689B2 (ja) * | 2016-09-16 | 2022-02-16 | 株式会社オンチップ・バイオテクノロジーズ | 微粒子分注装置、微粒子解析装置、及び反応検出装置、並びにそれらを用いる方法 |
WO2018094091A1 (en) * | 2016-11-17 | 2018-05-24 | Combinati Incorporated | Methods and systems for nucleic acid analysis and quantification |
AU2017366833B2 (en) * | 2016-12-02 | 2020-02-20 | EMULATE, Inc. | In vitro epithelial models comprising lamina propria-derived cells |
WO2018148194A1 (en) * | 2017-02-07 | 2018-08-16 | Nodexus Inc. | Microfluidic system with combined electrical and optical detection for high accuracy particle sorting and methods thereof |
KR101897250B1 (ko) * | 2017-07-11 | 2018-09-10 | 광주과학기술원 | 항암제 조합에 대한 단일 세포 분석 칩 |
US10391492B2 (en) * | 2017-08-29 | 2019-08-27 | Celsee Diagnostics, Inc. | System and method for isolating and analyzing cells |
TWI741658B (zh) | 2018-01-24 | 2021-10-01 | 美商伊路米納有限公司 | 流體緩衝 |
WO2019157136A2 (en) * | 2018-02-07 | 2019-08-15 | EMULATE, Inc. | Gas mixer and pressurizer apparatus |
JP7341148B2 (ja) * | 2018-02-16 | 2023-09-08 | アストレゴ ダイアグノスティクス エービー | 微小流体装置 |
EP3759486A1 (de) * | 2018-04-03 | 2021-01-06 | Hewlett-Packard Development Company, L.P. | Mikrofluidische kanäle zur beförderung von zellen unterschiedlicher grösse |
EP3790662A1 (de) * | 2018-06-21 | 2021-03-17 | Astraveus | Mikrofluidische vorrichtung und verfahren zur verarbeitung von partikeln |
US20210364410A1 (en) * | 2018-12-21 | 2021-11-25 | Sony Corporation | Particle confirming method, particle trapping chip, and particle analyzing system |
KR20220132413A (ko) * | 2019-04-24 | 2022-09-30 | 벤누바이오 인크. | 관심 표적 세포를 분류하고 풍부화시키기 위한 위치 지원 음성 입자 거부 (panr) |
EP4069423A1 (de) * | 2019-12-04 | 2022-10-12 | Astraveus | Mikrofluidische vorrichtung und verfahren zur verarbeitung von partikeln |
US20230191402A1 (en) * | 2020-05-18 | 2023-06-22 | National University Of Singapore | Microfluidic device and liquid control system therefor |
US20230263552A1 (en) * | 2020-07-06 | 2023-08-24 | Cornell University | Methods and devices for automated microfluidic oocyte denudation |
US11498067B2 (en) * | 2020-10-23 | 2022-11-15 | City University Of Hong Kong | Apparatus and a method for patterning biological cells |
Family Cites Families (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4119955C2 (de) | 1991-06-18 | 2000-05-31 | Danfoss As | Miniatur-Betätigungselement |
US5417235A (en) | 1993-07-28 | 1995-05-23 | Regents Of The University Of Michigan | Integrated microvalve structures with monolithic microflow controller |
BR9710054A (pt) | 1996-06-28 | 2000-01-11 | Caliper Techn Corp | Aparelhos para separar compostos de teste para um efeito sobre um sistema bioquìmico e para detectar ummefeito de um composto de teste sobre um sistema bioquìmico, processos de determinação de se uma amostra contém um composto capaz de afetar um sistema bioquìmico, de separação de uma pluralidade de compostos de teste para um efeito sobre um sistema bioquìmico e usos de um sistema microfluido e de um substrato de ensaio. |
US5785295A (en) | 1996-08-27 | 1998-07-28 | Industrial Technology Research Institute | Thermally buckling control microvalve |
AU746892B2 (en) | 1997-04-04 | 2002-05-02 | Caliper Life Sciences, Inc. | Closed-loop biochemical analyzers |
US6899137B2 (en) | 1999-06-28 | 2005-05-31 | California Institute Of Technology | Microfabricated elastomeric valve and pump systems |
KR100865105B1 (ko) | 1999-06-28 | 2008-10-24 | 캘리포니아 인스티튜트 오브 테크놀로지 | 마이크로 가공된 탄성중합체 밸브 및 펌프 시스템 |
US6645432B1 (en) | 2000-05-25 | 2003-11-11 | President & Fellows Of Harvard College | Microfluidic systems including three-dimensionally arrayed channel networks |
US7351376B1 (en) | 2000-06-05 | 2008-04-01 | California Institute Of Technology | Integrated active flux microfluidic devices and methods |
EP1322936A2 (de) | 2000-10-03 | 2003-07-02 | California Institute Of Technology | Mikrofluidvorrichtungen und verwendungsverfahren |
US7232109B2 (en) | 2000-11-06 | 2007-06-19 | California Institute Of Technology | Electrostatic valves for microfluidic devices |
US7378280B2 (en) | 2000-11-16 | 2008-05-27 | California Institute Of Technology | Apparatus and methods for conducting assays and high throughput screening |
US6960437B2 (en) | 2001-04-06 | 2005-11-01 | California Institute Of Technology | Nucleic acid amplification utilizing microfluidic devices |
US6752922B2 (en) | 2001-04-06 | 2004-06-22 | Fluidigm Corporation | Microfluidic chromatography |
US20020164816A1 (en) | 2001-04-06 | 2002-11-07 | California Institute Of Technology | Microfluidic sample separation device |
US7075162B2 (en) | 2001-08-30 | 2006-07-11 | Fluidigm Corporation | Electrostatic/electrostrictive actuation of elastomer structures using compliant electrodes |
JP4355210B2 (ja) | 2001-11-30 | 2009-10-28 | フルイディグム コーポレイション | 微小流体デバイスおよび微小流体デバイスの使用方法 |
WO2003085379A2 (en) | 2002-04-01 | 2003-10-16 | Fluidigm Corporation | Microfluidic particle-analysis systems |
US7312085B2 (en) * | 2002-04-01 | 2007-12-25 | Fluidigm Corporation | Microfluidic particle-analysis systems |
KR100990016B1 (ko) | 2002-09-16 | 2010-10-26 | 사이토놈/에스티, 엘엘씨 | 입자 선별 방법 및 장치 |
US8220494B2 (en) | 2002-09-25 | 2012-07-17 | California Institute Of Technology | Microfluidic large scale integration |
EP2213615A3 (de) | 2002-09-25 | 2012-02-29 | California Institute of Technology | Mikrofluidische Großintegration |
JP5695287B2 (ja) | 2002-10-02 | 2015-04-01 | カリフォルニア インスティテュート オブ テクノロジー | 微小流体の核酸解析 |
WO2004059299A1 (en) * | 2002-12-16 | 2004-07-15 | Cytodiscovery, Inc. | Microfluidic system with integrated permeable membrane |
US7604965B2 (en) | 2003-04-03 | 2009-10-20 | Fluidigm Corporation | Thermal reaction device and method for using the same |
US8268446B2 (en) | 2003-09-23 | 2012-09-18 | The University Of North Carolina At Chapel Hill | Photocurable perfluoropolyethers for use as novel materials in microfluidic devices |
US20070275193A1 (en) | 2004-02-13 | 2007-11-29 | Desimone Joseph M | Functional Materials and Novel Methods for the Fabrication of Microfluidic Devices |
EP2701194B1 (de) | 2004-06-07 | 2018-08-29 | Fluidigm Corporation | Verfahren und Vorrichtung zur Abbildung eines mikrofluidischen Geräts unter Temperaturkontrolle |
WO2006060748A2 (en) | 2004-12-03 | 2006-06-08 | California Institute Of Technology | Microfluidic sieve valves |
US20090317798A1 (en) * | 2005-06-02 | 2009-12-24 | Heid Christian A | Analysis using microfluidic partitioning devices |
WO2009089189A2 (en) * | 2008-01-03 | 2009-07-16 | Cellasic | Cell culture array system for automated assays and methods of operation and manufacture thereof |
US9329170B2 (en) | 2009-01-20 | 2016-05-03 | The Board Of Trustees Of The Leland Stanford Junior University | Single cell gene expression for diagnosis, prognosis and identification of drug targets |
JP5923035B2 (ja) * | 2009-03-24 | 2016-05-24 | バイオセプト インコーポレイティッド | 細胞の捕捉および解析のデバイスおよび方法 |
US20120100538A1 (en) * | 2009-03-24 | 2012-04-26 | Biocept, Inc. | Devices and methods of cell capture and analysis |
US9353406B2 (en) | 2010-10-22 | 2016-05-31 | Fluidigm Corporation | Universal probe assay methods |
US20120288857A1 (en) | 2011-02-03 | 2012-11-15 | Fluidigm Corporation | Multifunctional probe-primers |
CN108342453A (zh) | 2011-05-09 | 2018-07-31 | 富鲁达公司 | 基于探针的核酸检测 |
CN108531360A (zh) * | 2011-05-27 | 2018-09-14 | 不列颠哥伦比亚大学 | 用于高通量分析的微流控细胞捕获和分析设备 |
WO2012178166A1 (en) * | 2011-06-24 | 2012-12-27 | Arryx, Inc. | Method and apparatus for fractionating genetically distinct cells and cellular components |
US9429500B2 (en) | 2012-02-29 | 2016-08-30 | Fluidigm Corporation | Methods, systems and devices for multiple single-cell capturing and processing using microfluidics |
-
2014
- 2014-03-14 US US14/775,685 patent/US10578633B2/en active Active
- 2014-03-14 EP EP14763560.1A patent/EP2970849B1/de active Active
- 2014-03-14 SG SG11201504876TA patent/SG11201504876TA/en unknown
- 2014-03-14 CN CN201480009764.5A patent/CN105164246B/zh active Active
- 2014-03-14 CA CA2895638A patent/CA2895638A1/en not_active Abandoned
- 2014-03-14 JP JP2016503066A patent/JP2016521350A/ja active Pending
- 2014-03-14 EP EP19188137.4A patent/EP3581641A1/de not_active Withdrawn
- 2014-03-14 SG SG10201707485YA patent/SG10201707485YA/en unknown
- 2014-03-14 WO PCT/US2014/029344 patent/WO2014144789A2/en active Application Filing
-
2020
- 2020-01-24 US US16/752,073 patent/US20200264205A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
EP2970849A4 (de) | 2016-11-02 |
US20200264205A1 (en) | 2020-08-20 |
US10578633B2 (en) | 2020-03-03 |
SG10201707485YA (en) | 2017-10-30 |
EP2970849A2 (de) | 2016-01-20 |
CN105164246A (zh) | 2015-12-16 |
JP2016521350A (ja) | 2016-07-21 |
US20160025761A1 (en) | 2016-01-28 |
WO2014144789A3 (en) | 2014-12-24 |
EP2970849B1 (de) | 2019-08-21 |
CA2895638A1 (en) | 2014-09-18 |
CN105164246B (zh) | 2018-09-25 |
EP3581641A1 (de) | 2019-12-18 |
WO2014144789A2 (en) | 2014-09-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SG11201504876TA (en) | Methods and devices for analysis of defined multicellular combinations | |
IL252544A0 (en) | Devices and methods for analyzing mouse behavior | |
GB2547875B (en) | Methods for meta-genomics analysis of microbes | |
GB201309568D0 (en) | Methods and apparatus | |
EP2953041A4 (de) | Verfahren und vorrichtung zur analyse einer formoptimierung | |
EP2953040A4 (de) | Verfahren und vorrichtung zur analyse einer formoptimierung | |
PL3056056T3 (pl) | Sposób i układ wykrywania urządzeń | |
GB2513304B (en) | Peripheral apparatus and method of construction | |
PL3087198T3 (pl) | Metagenomowa analiza próbek | |
PL3071969T3 (pl) | Sposób analizy | |
EP2946614A4 (de) | Verfahren und vorrichtung | |
ZA201600927B (en) | Structural assembly and method of assembly thereof | |
EP2963410A4 (de) | Partikelanalysevorrichtung | |
GB201604534D0 (en) | Nucleic-acid-sequence determination device and nucleic-acid-sequence determination method | |
ZA201602719B (en) | Hydraulic devices and methods of actuating same | |
KR102377615B1 (ko) | 장치 및 사용 방법 | |
GB201319706D0 (en) | Real time analysis of big data | |
GB201301728D0 (en) | Telcommunications apparatus and methods | |
GB201421886D0 (en) | Metagenomic analysis of samples | |
EP2972190A4 (de) | Analysevorrichtung und -verfahren | |
GB201307787D0 (en) | Methods and Apparatus | |
EP2966433A4 (de) | Vorrichtung zur einstellung eines interessebereichs zur analyse | |
TWM475581U (en) | Analysis system of behavior | |
GB2519734B (en) | Apparatus and Methods | |
GB201316737D0 (en) | Apparatus and Methods |