SG11201504334WA - Methods for targeted genomic analysis - Google Patents
Methods for targeted genomic analysisInfo
- Publication number
- SG11201504334WA SG11201504334WA SG11201504334WA SG11201504334WA SG11201504334WA SG 11201504334W A SG11201504334W A SG 11201504334WA SG 11201504334W A SG11201504334W A SG 11201504334WA SG 11201504334W A SG11201504334W A SG 11201504334WA SG 11201504334W A SG11201504334W A SG 11201504334WA
- Authority
- SG
- Singapore
- Prior art keywords
- methods
- genomic analysis
- targeted genomic
- targeted
- analysis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261735417P | 2012-12-10 | 2012-12-10 | |
| US201361794049P | 2013-03-15 | 2013-03-15 | |
| PCT/US2013/074102 WO2014093330A1 (en) | 2012-12-10 | 2013-12-10 | Methods for targeted genomic analysis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201504334WA true SG11201504334WA (en) | 2015-07-30 |
Family
ID=50934888
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201504334WA SG11201504334WA (en) | 2012-12-10 | 2013-12-10 | Methods for targeted genomic analysis |
| SG10201704633UA SG10201704633UA (en) | 2012-12-10 | 2013-12-10 | Methods for targeted genomic analysis |
| SG10202009015SA SG10202009015SA (en) | 2012-12-10 | 2013-12-10 | Methods for targeted genomic analysis |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201704633UA SG10201704633UA (en) | 2012-12-10 | 2013-12-10 | Methods for targeted genomic analysis |
| SG10202009015SA SG10202009015SA (en) | 2012-12-10 | 2013-12-10 | Methods for targeted genomic analysis |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US9932576B2 (en) |
| EP (3) | EP4293125A3 (en) |
| JP (5) | JP6410726B2 (en) |
| CN (3) | CN117845337A (en) |
| CA (1) | CA2892646A1 (en) |
| HK (1) | HK1213944A1 (en) |
| SG (3) | SG11201504334WA (en) |
| WO (1) | WO2014093330A1 (en) |
Families Citing this family (99)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010127186A1 (en) | 2009-04-30 | 2010-11-04 | Prognosys Biosciences, Inc. | Nucleic acid constructs and methods of use |
| US20190300945A1 (en) | 2010-04-05 | 2019-10-03 | Prognosys Biosciences, Inc. | Spatially Encoded Biological Assays |
| US10787701B2 (en) | 2010-04-05 | 2020-09-29 | Prognosys Biosciences, Inc. | Spatially encoded biological assays |
| WO2011127099A1 (en) | 2010-04-05 | 2011-10-13 | Prognosys Biosciences, Inc. | Spatially encoded biological assays |
| GB201106254D0 (en) | 2011-04-13 | 2011-05-25 | Frisen Jonas | Method and product |
| WO2013059746A1 (en) | 2011-10-19 | 2013-04-25 | Nugen Technologies, Inc. | Compositions and methods for directional nucleic acid amplification and sequencing |
| CN105861487B (en) | 2012-01-26 | 2020-05-05 | 纽亘技术公司 | Compositions and methods for targeted nucleic acid sequence enrichment and efficient library generation |
| GB2518078B (en) | 2012-06-18 | 2015-04-29 | Nugen Technologies Inc | Compositions and methods for negative selection of non-desired nucleic acid sequences |
| US20150011396A1 (en) | 2012-07-09 | 2015-01-08 | Benjamin G. Schroeder | Methods for creating directional bisulfite-converted nucleic acid libraries for next generation sequencing |
| US10876152B2 (en) | 2012-09-04 | 2020-12-29 | Guardant Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
| US11913065B2 (en) | 2012-09-04 | 2024-02-27 | Guardent Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
| US20160040229A1 (en) | 2013-08-16 | 2016-02-11 | Guardant Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
| PT2893040T (en) | 2012-09-04 | 2019-04-01 | Guardant Health Inc | Systems and methods to detect rare mutations and copy number variation |
| CN117845337A (en) | 2012-12-10 | 2024-04-09 | 分析生物科学有限公司 | Methods of targeted genomic analysis |
| CA2901907C (en) * | 2013-02-20 | 2023-06-20 | Emory University | Methods of sequencing nucleic acids in mixtures and compositions related thereto |
| EP2971130A4 (en) | 2013-03-15 | 2016-10-05 | Nugen Technologies Inc | Sequential sequencing |
| WO2014210225A1 (en) | 2013-06-25 | 2014-12-31 | Prognosys Biosciences, Inc. | Methods and systems for determining spatial patterns of biological targets in a sample |
| US9409139B2 (en) | 2013-08-05 | 2016-08-09 | Twist Bioscience Corporation | De novo synthesized gene libraries |
| JP6525473B2 (en) | 2013-11-13 | 2019-06-05 | ニューゲン テクノロジーズ， インコーポレイテッド | Compositions and methods for identifying replicate sequencing leads |
| AU2014369841B2 (en) | 2013-12-28 | 2019-01-24 | Guardant Health, Inc. | Methods and systems for detecting genetic variants |
| WO2015131107A1 (en) | 2014-02-28 | 2015-09-03 | Nugen Technologies, Inc. | Reduced representation bisulfite sequencing with diversity adaptors |
| JP7441584B6 (en) * | 2014-08-22 | 2024-03-15 | レゾリューション バイオサイエンス， インコーポレイテッド | Method for quantitative genetic analysis of cell-free DNA (cfDNA) |
| WO2016028316A1 (en) * | 2014-08-22 | 2016-02-25 | Resolution Bioscience, Inc. | Methods for quantitative genetic analysis of cell free dna |
| JP2017537657A (en) * | 2014-12-11 | 2017-12-21 | ニユー・イングランド・バイオレイブス・インコーポレイテツド | Target sequence enrichment |
| CA2975852A1 (en) | 2015-02-04 | 2016-08-11 | Twist Bioscience Corporation | Methods and devices for de novo oligonucleic acid assembly |
| WO2016161177A1 (en) * | 2015-03-31 | 2016-10-06 | Fred Hutchinson Cancer Research Center | Compositions and methods for target nucleic acid molecule enrichment |
| EP3530752B1 (en) | 2015-04-10 | 2021-03-24 | Spatial Transcriptomics AB | Spatially distinguished, multiplex nucleic acid analysis of biological specimens |
| US9981239B2 (en) | 2015-04-21 | 2018-05-29 | Twist Bioscience Corporation | Devices and methods for oligonucleic acid library synthesis |
| EP3653728B1 (en) | 2015-06-09 | 2023-02-01 | Life Technologies Corporation | Methods, systems, compositions, kits, apparatus and computer-readable media for molecular tagging |
| AU2016324296A1 (en) | 2015-09-18 | 2018-04-12 | Twist Bioscience Corporation | Oligonucleic acid variant libraries and synthesis thereof |
| US11512347B2 (en) | 2015-09-22 | 2022-11-29 | Twist Bioscience Corporation | Flexible substrates for nucleic acid synthesis |
| KR20180113973A (en) * | 2015-11-11 | 2018-10-17 | 레졸루션 바이오사이언스, 인크. | High-efficiency construction of DNA library |
| CN115920796A (en) | 2015-12-01 | 2023-04-07 | 特韦斯特生物科学公司 | Functionalized surfaces and preparation thereof |
| EP3390668A4 (en) | 2015-12-17 | 2020-04-01 | Guardant Health, Inc. | Methods to determine tumor gene copy number by analysis of cell-free dna |
| EP3390671B1 (en) * | 2016-02-11 | 2019-10-09 | HTG Molecular Diagnostics, Inc. | Method of direct target sequencing using nuclease protection |
| US10240196B2 (en) | 2016-05-27 | 2019-03-26 | Agilent Technologies, Inc. | Transposase-random priming DNA sample preparation |
| CN107058310A (en) * | 2016-08-12 | 2017-08-18 | 艾吉泰康生物科技(北京)有限公司 | A kind of amplicon library constructing method for improving gene low frequency abrupt climatic change sensitivity |
| CA3034769A1 (en) | 2016-08-22 | 2018-03-01 | Twist Bioscience Corporation | De novo synthesized nucleic acid libraries |
| RU2019108294A (en) | 2016-08-25 | 2020-09-25 | Резолюшн Байосайенс, Инк. | METHODS FOR DETECTING CHANGES IN THE AMOUNT OF GENOMIC COPIES IN DNA SAMPLES |
| WO2018057526A2 (en) | 2016-09-21 | 2018-03-29 | Twist Bioscience Corporation | Nucleic acid based data storage |
| US10907274B2 (en) | 2016-12-16 | 2021-02-02 | Twist Bioscience Corporation | Variant libraries of the immunological synapse and synthesis thereof |
| CN110892485B (en) | 2017-02-22 | 2024-03-22 | 特韦斯特生物科学公司 | Nucleic acid-based data storage |
| EP3595674A4 (en) | 2017-03-15 | 2020-12-16 | Twist Bioscience Corporation | Variant libraries of the immunological synapse and synthesis thereof |
| US10696965B2 (en) | 2017-06-12 | 2020-06-30 | Twist Bioscience Corporation | Methods for seamless nucleic acid assembly |
| WO2018231864A1 (en) | 2017-06-12 | 2018-12-20 | Twist Bioscience Corporation | Methods for seamless nucleic acid assembly |
| JP7402503B2 (en) | 2017-06-14 | 2023-12-21 | テクニスチェ ユニベルシタト ドレスデン | Methods and means for genetically modifying the genome using designer DNA recombinase |
| EP3681906A4 (en) | 2017-09-11 | 2021-06-09 | Twist Bioscience Corporation | Gpcr binding proteins and synthesis thereof |
| US11099202B2 (en) | 2017-10-20 | 2021-08-24 | Tecan Genomics, Inc. | Reagent delivery system |
| GB2583590A (en) | 2017-10-20 | 2020-11-04 | Twist Bioscience Corp | Heated nanowells for polynucleotide synthesis |
| US20210371853A1 (en) * | 2017-12-09 | 2021-12-02 | Viome, Inc. | Methods for nucleic acid library creation |
| KR20200106067A (en) | 2018-01-04 | 2020-09-10 | 트위스트 바이오사이언스 코포레이션 | DNA-based digital information storage |
| US11264119B2 (en) | 2018-01-10 | 2022-03-01 | Memorial Sloan Kettering Cancer Center | Generating configurable text strings based on raw genomic data |
| SG11202011467RA (en) | 2018-05-18 | 2020-12-30 | Twist Bioscience Corp | Polynucleotides, reagents, and methods for nucleic acid hybridization |
| CN108866155B (en) * | 2018-06-11 | 2022-07-26 | 中国农业科学院深圳农业基因组研究所 | Preparation method of next generation sequencing library |
| CN112639127A (en) * | 2018-06-25 | 2021-04-09 | 路胜生命科学私人有限公司 | Method for detecting and quantifying genetic alterations |
| US20210292750A1 (en) * | 2018-07-24 | 2021-09-23 | Ripple Biosolutions Llc | Methods and composition for targeted genomic analysis |
| WO2020037281A1 (en) * | 2018-08-17 | 2020-02-20 | Dana-Farber Cancer Institute, Inc. | Dna amplification method for probe generation |
| US11519033B2 (en) | 2018-08-28 | 2022-12-06 | 10X Genomics, Inc. | Method for transposase-mediated spatial tagging and analyzing genomic DNA in a biological sample |
| AU2018440274B2 (en) | 2018-09-07 | 2023-02-16 | Fujitsu Limited | Identification method, identification program, and information processing device |
| EP3894587A1 (en) | 2018-12-10 | 2021-10-20 | 10X Genomics, Inc. | Resolving spatial arrays by proximity-based deconvolution |
| US11649485B2 (en) | 2019-01-06 | 2023-05-16 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| US11926867B2 (en) | 2019-01-06 | 2024-03-12 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| KR20210143766A (en) | 2019-02-26 | 2021-11-29 | 트위스트 바이오사이언스 코포레이션 | Variant Nucleic Acid Libraries for the GLP1 Receptor |
| WO2020176680A1 (en) | 2019-02-26 | 2020-09-03 | Twist Bioscience Corporation | Variant nucleic acid libraries for antibody optimization |
| WO2020243579A1 (en) | 2019-05-30 | 2020-12-03 | 10X Genomics, Inc. | Methods of detecting spatial heterogeneity of a biological sample |
| CA3144644A1 (en) | 2019-06-21 | 2020-12-24 | Twist Bioscience Corporation | Barcode-based nucleic acid sequence assembly |
| EP4013867A4 (en) * | 2019-08-16 | 2023-08-30 | Resolution Bioscience, Inc. | Targeted hybrid capture methods for determination of t cell repertoires |
| WO2021091611A1 (en) | 2019-11-08 | 2021-05-14 | 10X Genomics, Inc. | Spatially-tagged analyte capture agents for analyte multiplexing |
| EP4025711A2 (en) | 2019-11-08 | 2022-07-13 | 10X Genomics, Inc. | Enhancing specificity of analyte binding |
| EP3831939A1 (en) * | 2019-12-06 | 2021-06-09 | Technische Universität Dresden | Fusion of site-specific recombinases for efficient and specific genome editing |
| EP3891300B1 (en) | 2019-12-23 | 2023-03-29 | 10X Genomics, Inc. | Methods for spatial analysis using rna-templated ligation |
| US11732299B2 (en) | 2020-01-21 | 2023-08-22 | 10X Genomics, Inc. | Spatial assays with perturbed cells |
| US11702693B2 (en) | 2020-01-21 | 2023-07-18 | 10X Genomics, Inc. | Methods for printing cells and generating arrays of barcoded cells |
| US11821035B1 (en) | 2020-01-29 | 2023-11-21 | 10X Genomics, Inc. | Compositions and methods of making gene expression libraries |
| US11898205B2 (en) | 2020-02-03 | 2024-02-13 | 10X Genomics, Inc. | Increasing capture efficiency of spatial assays |
| US11732300B2 (en) | 2020-02-05 | 2023-08-22 | 10X Genomics, Inc. | Increasing efficiency of spatial analysis in a biological sample |
| US11835462B2 (en) | 2020-02-11 | 2023-12-05 | 10X Genomics, Inc. | Methods and compositions for partitioning a biological sample |
| US11891654B2 (en) | 2020-02-24 | 2024-02-06 | 10X Genomics, Inc. | Methods of making gene expression libraries |
| US11926863B1 (en) | 2020-02-27 | 2024-03-12 | 10X Genomics, Inc. | Solid state single cell method for analyzing fixed biological cells |
| US11768175B1 (en) | 2020-03-04 | 2023-09-26 | 10X Genomics, Inc. | Electrophoretic methods for spatial analysis |
| WO2021216708A1 (en) | 2020-04-22 | 2021-10-28 | 10X Genomics, Inc. | Methods for spatial analysis using targeted rna depletion |
| WO2021236929A1 (en) | 2020-05-22 | 2021-11-25 | 10X Genomics, Inc. | Simultaneous spatio-temporal measurement of gene expression and cellular activity |
| WO2021237087A1 (en) | 2020-05-22 | 2021-11-25 | 10X Genomics, Inc. | Spatial analysis to detect sequence variants |
| WO2021242834A1 (en) | 2020-05-26 | 2021-12-02 | 10X Genomics, Inc. | Method for resetting an array |
| AU2021283174A1 (en) | 2020-06-02 | 2023-01-05 | 10X Genomics, Inc. | Nucleic acid library methods |
| WO2021247568A1 (en) | 2020-06-02 | 2021-12-09 | 10X Genomics, Inc. | Spatial trancriptomics for antigen-receptors |
| EP4162074B1 (en) | 2020-06-08 | 2024-04-24 | 10X Genomics, Inc. | Methods of determining a surgical margin and methods of use thereof |
| WO2021252591A1 (en) | 2020-06-10 | 2021-12-16 | 10X Genomics, Inc. | Methods for determining a location of an analyte in a biological sample |
| CN116034166A (en) | 2020-06-25 | 2023-04-28 | 10X基因组学有限公司 | Spatial analysis of DNA methylation |
| US11761038B1 (en) | 2020-07-06 | 2023-09-19 | 10X Genomics, Inc. | Methods for identifying a location of an RNA in a biological sample |
| CN116194593A (en) * | 2020-07-23 | 2023-05-30 | 合成Dna技术公司 | Method for naming target/off-target editing sites in nucleases called "CTL-seq" (CRISPR Tag Linear-seq) |
| US11926822B1 (en) | 2020-09-23 | 2024-03-12 | 10X Genomics, Inc. | Three-dimensional spatial analysis |
| US11827935B1 (en) | 2020-11-19 | 2023-11-28 | 10X Genomics, Inc. | Methods for spatial analysis using rolling circle amplification and detection probes |
| CN112481371A (en) * | 2020-12-11 | 2021-03-12 | 长沙金域医学检验实验室有限公司 | Kit for detecting copy number variation of PLP1 gene |
| AU2021409136A1 (en) | 2020-12-21 | 2023-06-29 | 10X Genomics, Inc. | Methods, compositions, and systems for capturing probes and/or barcodes |
| EP4301870A1 (en) | 2021-03-18 | 2024-01-10 | 10X Genomics, Inc. | Multiplex capture of gene and protein expression from a biological sample |
| JP2024512156A (en) * | 2021-03-30 | 2024-03-18 | レゾリューション バイオサイエンス， インコーポレイテッド | Compositions and methods for simultaneous genetic analysis of multiple libraries |
| EP4196605A1 (en) | 2021-09-01 | 2023-06-21 | 10X Genomics, Inc. | Methods, compositions, and kits for blocking a capture probe on a spatial array |
| CN114898802B (en) * | 2022-07-14 | 2022-09-30 | 臻和(北京)生物科技有限公司 | Terminal sequence frequency distribution characteristic determination method, evaluation method and device based on plasma free DNA methylation sequencing data |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6480791B1 (en) * | 1998-10-28 | 2002-11-12 | Michael P. Strathmann | Parallel methods for genomic analysis |
| WO2003052116A2 (en) | 2001-07-17 | 2003-06-26 | Stratagene | Methods for detection of a target nucleic acid using multi-subunit probes |
| WO2003020979A1 (en) | 2001-08-31 | 2003-03-13 | Rosetta Inpharmactis Llc. | Methods for preparing nucleic acid samples |
| GB0522310D0 (en) * | 2005-11-01 | 2005-12-07 | Solexa Ltd | Methods of preparing libraries of template polynucleotides |
| WO2007087312A2 (en) | 2006-01-23 | 2007-08-02 | Population Genetics Technologies Ltd. | Molecular counting |
| US7754429B2 (en) | 2006-10-06 | 2010-07-13 | Illumina Cambridge Limited | Method for pair-wise sequencing a plurity of target polynucleotides |
| EP2076609A1 (en) | 2006-10-10 | 2009-07-08 | Illumina Inc. | Compositions and methods for representational selection of nucleic acids fro complex mixtures using hybridization |
| US9388457B2 (en) * | 2007-09-14 | 2016-07-12 | Affymetrix, Inc. | Locus specific amplification using array probes |
| WO2009091798A1 (en) | 2008-01-16 | 2009-07-23 | Helicos Biosciences Corporation | Quantitative genetic analysis |
| US8202691B2 (en) | 2008-01-25 | 2012-06-19 | Illumina, Inc. | Uniform fragmentation of DNA using binding proteins |
| ES2528971T3 (en) * | 2008-03-17 | 2015-02-13 | Stichting Genetwister Ip | Discoveries of genes linked to expression |
| JP5794572B2 (en) * | 2008-10-24 | 2015-10-14 | エピセンター テクノロジーズ コーポレイションＥｐｉｃｅｎｔｒｅ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｃｏｒｐｏｒａｔｉｏｎ | Transposon end compositions and methods for modifying nucleic acids |
| CA3018687C (en) | 2009-04-02 | 2021-07-13 | Fluidigm Corporation | Multi-primer amplification method for barcoding of target nucleic acids |
| WO2010129937A2 (en) | 2009-05-08 | 2010-11-11 | Life Technologies Corporation | Methods for detecting genetic variations in dna samples |
| US8835358B2 (en) * | 2009-12-15 | 2014-09-16 | Cellular Research, Inc. | Digital counting of individual molecules by stochastic attachment of diverse labels |
| US8828688B2 (en) * | 2010-05-27 | 2014-09-09 | Affymetrix, Inc. | Multiplex amplification methods |
| EP2580378A4 (en) | 2010-06-08 | 2014-01-01 | Nugen Technologies Inc | Methods and composition for multiplex sequencing |
| KR20130113447A (en) * | 2010-09-24 | 2013-10-15 | 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 | Direct capture, amplification and sequencing of target dna using immobilized primers |
| US9260753B2 (en) * | 2011-03-24 | 2016-02-16 | President And Fellows Of Harvard College | Single cell nucleic acid detection and analysis |
| US20130288915A1 (en) | 2012-04-27 | 2013-10-31 | Htg Molecular Diagnostics, Inc. | Compositions and methods for alk molecular testing |
| CA2872141C (en) | 2012-05-31 | 2016-01-19 | Board Of Regents, The University Of Texas System | Method for accurate sequencing of dna |
| US20150291953A1 (en) | 2012-11-02 | 2015-10-15 | Enzymatics Inc. | Methods and kits for nucleic acid sample preparation for sequencing |
| CN117845337A (en) | 2012-12-10 | 2024-04-09 | 分析生物科学有限公司 | Methods of targeted genomic analysis |
| WO2014122288A1 (en) | 2013-02-08 | 2014-08-14 | Qiagen Gmbh | Method for separating dna by size |
| AU2014233373B2 (en) | 2013-03-15 | 2019-10-24 | Verinata Health, Inc. | Generating cell-free DNA libraries directly from blood |
| WO2015134552A1 (en) | 2014-03-03 | 2015-09-11 | Swift Biosciences, Inc. | Enhanced adaptor ligation |
| US20160053301A1 (en) | 2014-08-22 | 2016-02-25 | Clearfork Bioscience, Inc. | Methods for quantitative genetic analysis of cell free dna |
| WO2016028316A1 (en) | 2014-08-22 | 2016-02-25 | Resolution Bioscience, Inc. | Methods for quantitative genetic analysis of cell free dna |
| KR20180113973A (en) | 2015-11-11 | 2018-10-17 | 레졸루션 바이오사이언스, 인크. | High-efficiency construction of DNA library |
-
2013
- 2013-12-10 CN CN202311824187.2A patent/CN117845337A/en active Pending
- 2013-12-10 WO PCT/US2013/074102 patent/WO2014093330A1/en active Application Filing
- 2013-12-10 SG SG11201504334WA patent/SG11201504334WA/en unknown
- 2013-12-10 CN CN201380072169.1A patent/CN105531375B/en active Active
- 2013-12-10 EP EP23186301.0A patent/EP4293125A3/en active Pending
- 2013-12-10 EP EP13862440.8A patent/EP2929056A4/en not_active Withdrawn
- 2013-12-10 US US14/102,285 patent/US9932576B2/en active Active
- 2013-12-10 CA CA2892646A patent/CA2892646A1/en active Pending
- 2013-12-10 EP EP19153893.3A patent/EP3561072A1/en not_active Withdrawn
- 2013-12-10 SG SG10201704633UA patent/SG10201704633UA/en unknown
- 2013-12-10 SG SG10202009015SA patent/SG10202009015SA/en unknown
- 2013-12-10 JP JP2015545927A patent/JP6410726B2/en active Active
- 2013-12-10 CN CN202010078573.1A patent/CN111254500B/en active Active
-
2016
- 2016-02-17 HK HK16101684.1A patent/HK1213944A1/en unknown
-
2018
- 2018-01-17 US US15/873,510 patent/US10907149B2/en active Active
- 2018-09-25 JP JP2018178774A patent/JP6842450B2/en active Active
-
2021
- 2021-01-05 US US17/141,510 patent/US20210198658A1/en active Pending
- 2021-02-19 JP JP2021025425A patent/JP7223790B2/en active Active
- 2021-11-10 JP JP2021183083A patent/JP7377247B2/en active Active
-
2023
- 2023-10-27 JP JP2023184894A patent/JP2023182855A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US9932576B2 (en) | 2018-04-03 |
| CN111254500A (en) | 2020-06-09 |
| US20180142234A1 (en) | 2018-05-24 |
| WO2014093330A1 (en) | 2014-06-19 |
| CN117845337A (en) | 2024-04-09 |
| CA2892646A1 (en) | 2014-06-19 |
| US20140274731A1 (en) | 2014-09-18 |
| JP6410726B2 (en) | 2018-10-24 |
| US20210198658A1 (en) | 2021-07-01 |
| EP2929056A1 (en) | 2015-10-14 |
| EP4293125A2 (en) | 2023-12-20 |
| EP2929056A4 (en) | 2016-11-09 |
| JP7223790B2 (en) | 2023-02-16 |
| JP2022025140A (en) | 2022-02-09 |
| CN111254500B (en) | 2024-01-23 |
| JP2015536156A (en) | 2015-12-21 |
| HK1213944A1 (en) | 2016-07-15 |
| JP7377247B2 (en) | 2023-11-09 |
| JP2019004910A (en) | 2019-01-17 |
| US10907149B2 (en) | 2021-02-02 |
| JP2023182855A (en) | 2023-12-26 |
| EP3561072A1 (en) | 2019-10-30 |
| CN105531375A (en) | 2016-04-27 |
| JP6842450B2 (en) | 2021-03-17 |
| SG10201704633UA (en) | 2017-07-28 |
| SG10202009015SA (en) | 2020-10-29 |
| JP2021078515A (en) | 2021-05-27 |
| CN105531375B (en) | 2020-03-03 |
| EP4293125A3 (en) | 2024-02-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1213944A1 (en) | Methods for targeted genomic analysis | |
| IL255724A (en) | Malware analysis system | |
| HK1250690A1 (en) | Methods | |
| IL245935A0 (en) | Methods for rna analysis | |
| ZA201307225B (en) | Methods for genomic modification | |
| EP2814984A4 (en) | Mirna analysis methods | |
| ZA201501833B (en) | Method for obtaining 1-kestone | |
| LT3305918T (en) | Methods for epigenetic sequencing | |
| EP2768983A4 (en) | Analysis methods | |
| EP2682755A4 (en) | Analysis device | |
| EP2832465A4 (en) | Press-forming analysis method | |
| EP2878953A4 (en) | Analysis device | |
| EP2693217A4 (en) | Analysis device | |
| EP2891709A4 (en) | Nucleic acid analysis device | |
| HK1190459A1 (en) | Analysis device | |
| EP2685257A4 (en) | Analysis method | |
| GB201212934D0 (en) | Method | |
| LT2852602T (en) | Method for conjugating oligonucleotides | |
| EP2708884A4 (en) | Distribution analysis device | |
| GB2507760B (en) | Methods | |
| EP2672272A4 (en) | Analysis device | |
| EP2880048A4 (en) | Method | |
| GB201208874D0 (en) | Methods | |
| EP2899655A4 (en) | Analysis device | |
| GB201204280D0 (en) | Methods |