SG11201504076XA - Aryl and heteroaryl fused lactams - Google Patents
Aryl and heteroaryl fused lactamsInfo
- Publication number
- SG11201504076XA SG11201504076XA SG11201504076XA SG11201504076XA SG11201504076XA SG 11201504076X A SG11201504076X A SG 11201504076XA SG 11201504076X A SG11201504076X A SG 11201504076XA SG 11201504076X A SG11201504076X A SG 11201504076XA SG 11201504076X A SG11201504076X A SG 11201504076XA
- Authority
- SG
- Singapore
- Prior art keywords
- aryl
- heteroaryl fused
- fused lactams
- lactams
- heteroaryl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epidemiology (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261740596P | 2012-12-21 | 2012-12-21 | |
| PCT/IB2013/060682 WO2014097041A1 (en) | 2012-12-21 | 2013-12-05 | Aryl and heteroaryl fused lactams |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201504076XA true SG11201504076XA (en) | 2015-06-29 |
Family
ID=49917684
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201504076XA SG11201504076XA (en) | 2012-12-21 | 2013-12-05 | Aryl and heteroaryl fused lactams |
Country Status (47)
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2780013A4 (en) | 2011-11-18 | 2015-07-01 | Constellation Pharmaceuticals Inc | Modulators of methyl modifying enzymes, compositions and uses thereof |
| WO2013120104A2 (en) | 2012-02-10 | 2013-08-15 | Constellation Pharmaceuticals | Modulators of methyl modifying enzymes, compositions and uses thereof |
| AR092742A1 (en) | 2012-10-02 | 2015-04-29 | Intermune Inc | ANTIFIBROTIC PYRIDINONES |
| UA111305C2 (en) * | 2012-12-21 | 2016-04-11 | Пфайзер Інк. | Condensed with lactams of aryl and heteroaryl |
| CN110684067A (en) | 2012-12-21 | 2020-01-14 | 艾丽奥斯生物制药有限公司 | Substituted nucleosides and nucleotides |
| EP2970305B1 (en) | 2013-03-15 | 2017-02-22 | Constellation Pharmaceuticals, Inc. | Modulators of methyl modifying enzymes, compositions and uses thereof |
| WO2015023915A1 (en) | 2013-08-15 | 2015-02-19 | Constellation Pharmaceuticals, Inc. | Indole derivatives as modulators of methyl modifying enzymes, compositions and uses thereof |
| ES2721031T3 (en) * | 2014-06-17 | 2019-07-26 | Pfizer | Dihydroisoquinolinone substituted compounds |
| WO2015193768A1 (en) * | 2014-06-17 | 2015-12-23 | Pfizer Inc. | Aryl fused lactams as ezh2 modulators |
| CN107148419A (en) * | 2014-10-28 | 2017-09-08 | 葛兰素史密斯克莱知识产权（第2 号）有限公司 | The inhibitor of ZESTE enhancers homologue 2 |
| TW201636344A (en) | 2014-12-05 | 2016-10-16 | 美國禮來大藥廠 | Inhibitors of EZH2 |
| EP3236962A2 (en) | 2014-12-23 | 2017-11-01 | University of Copenhagen | Treatment of cancer by inhibiting ezh2 activity |
| WO2016156085A1 (en) * | 2015-03-27 | 2016-10-06 | Syngenta Participations Ag | Microbiocidal heterobicyclic derivatives |
| UY36758A (en) * | 2015-06-30 | 2016-12-30 | Glaxosmithkline Ip No 2 Ltd | INHIBITORS OF THE ZESTE 2 HOMOLOGIST POTENTIATOR |
| TW201718598A (en) | 2015-08-27 | 2017-06-01 | 美國禮來大藥廠 | Inhibitors of EZH2 |
| US10577350B2 (en) | 2015-08-28 | 2020-03-03 | Constellation Pharmaceuticals, Inc. | Crystalline forms of (R)-N-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide |
| RS59763B1 (en) | 2015-11-19 | 2020-02-28 | Jiangsu hengrui medicine co ltd | Benzofuran derivative, preparation method thereof and use thereof in medicine |
| CR20180521A (en) * | 2016-05-05 | 2019-01-15 | Glaxosmithkline Ip No 2 Ltd | INHIBITORS OF THE ZESTE 2 HOMOLOGIST POTENTIATOR |
| EP3529242A1 (en) | 2016-10-19 | 2019-08-28 | Constellation Pharmaceuticals, Inc. | Synthesis of inhibitors of ezh2 |
| CN108699002B (en) * | 2016-11-11 | 2021-11-09 | 上海海雁医药科技有限公司 | 1,5, 7-trisubstituted isoquinoline derivative, preparation method and medical application thereof |
| US10266542B2 (en) | 2017-03-15 | 2019-04-23 | Mirati Therapeutics, Inc. | EZH2 inhibitors |
| WO2018210302A1 (en) | 2017-05-18 | 2018-11-22 | 江苏恒瑞医药股份有限公司 | Crystal of benzofuran derivative free base and preparation method |
| JP7125952B2 (en) | 2017-05-18 | 2022-08-25 | 江蘇恒瑞医薬股▲ふん▼有限公司 | Use of an EZH2 inhibitor in combination with a BTK inhibitor in the manufacture of a medicament for treating tumors |
| CN106977483A (en) * | 2017-06-02 | 2017-07-25 | 遵义医学院 | A kind of synthetic method of the flavonols of fluoroalkyl substitution, isoflavones alcohol and coumarin kind compound |
| WO2019097369A1 (en) | 2017-11-14 | 2019-05-23 | Pfizer Inc. | Ezh2 inhibitor combination therapies |
| MX2020007974A (en) | 2018-01-31 | 2020-09-07 | Mirati Therapeutics Inc | Prc2 inhibitors. |
| EP4155293A1 (en) * | 2018-06-07 | 2023-03-29 | The Regents of The University of Michigan | Prc1 inhibitors and methods of treatment therewith |
| JP2021531340A (en) | 2018-07-09 | 2021-11-18 | フォンダシヨン、アジール、デ、アブグルスFondation Asile Des Aveugles | Inhibition of the PRC2 subunit to treat eye disorders |
| US11999716B2 (en) * | 2018-10-24 | 2024-06-04 | Vanderbilt University | WDR5 inhibitors and modulators |
| CN111320582A (en) * | 2018-12-17 | 2020-06-23 | 江苏恩华药业股份有限公司 | Preparation method of amide-like derivative and intermediate thereof |
| KR102689665B1 (en) * | 2019-02-19 | 2024-07-31 | 한미약품 주식회사 | Novel heterotricyclic derivatives and use thereof |
| KR102386403B1 (en) * | 2020-08-13 | 2022-04-15 | 한미약품 주식회사 | Novel dioxoloisoquinolinone derivatives and use thereof |
| EP4196483A1 (en) | 2020-08-13 | 2023-06-21 | Hanmi Pharmaceutical Co., Ltd. | Novel dioxoloisoquinolinone derivatives and use thereof |
| WO2022179584A1 (en) * | 2021-02-26 | 2022-09-01 | 南京药石科技股份有限公司 | New ezh2 inhibitor and use thereof |
| WO2024126650A1 (en) | 2022-12-15 | 2024-06-20 | Syngenta Crop Protection Ag | Novel bicyclic-carboxamide compounds useful as pesticides |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3846412A (en) | 1971-03-18 | 1974-11-05 | Lepetit Spa | Dihydro-2-amino-isoquinolines and their derivatives |
| KR0166088B1 (en) | 1990-01-23 | 1999-01-15 | . | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
| US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
| GB9518953D0 (en) | 1995-09-15 | 1995-11-15 | Pfizer Ltd | Pharmaceutical formulations |
| WO2000035298A1 (en) | 1996-11-27 | 2000-06-22 | Wm. Wrigley Jr. Company | Chewing gum containing medicament active agents |
| GB9711643D0 (en) | 1997-06-05 | 1997-07-30 | Janssen Pharmaceutica Nv | Glass thermoplastic systems |
| FR2889526B1 (en) | 2005-08-04 | 2012-02-17 | Aventis Pharma Sa | SUBSTITUTED 7-AZA-INDAZOLES, COMPOSITIONS CONTAINING SAME, PROCESS FOR PRODUCTION AND USE |
| CA2619462A1 (en) | 2005-08-16 | 2007-02-22 | Amgen, Inc. | Phosphodiesterase 10 inhibitors |
| US20100113415A1 (en) | 2008-05-29 | 2010-05-06 | Rajapakse Hemaka A | Epha4 rtk inhibitors for treatment of neurological and neurodegenerative disorders and cancer |
| WO2011103016A2 (en) | 2010-02-19 | 2011-08-25 | The Regents Of The University Of Michigan | Compositions and methods for inhibiting ezh2 |
| EP2566328B1 (en) | 2010-05-07 | 2015-03-04 | GlaxoSmithKline LLC | Indazoles |
| WO2012005805A1 (en) | 2010-05-07 | 2012-01-12 | Glaxosmithkline Llc | Azaindazoles |
| PT2566327T (en) | 2010-05-07 | 2017-05-26 | Glaxosmithkline Llc | Indoles |
| EP2614369B1 (en) | 2010-09-10 | 2016-02-03 | Epizyme, Inc. | Method for determining the suitability of inhibitors of human ezh2 in treatment |
| US8946260B2 (en) | 2010-09-16 | 2015-02-03 | Novartis Ag | 17α-hydroxylase/C17,20-lyase inhibitors |
| US20130310379A1 (en) | 2010-11-19 | 2013-11-21 | Constellation Pharmaceuticals | Modulators of methyl modifying enzymes, compositions and uses thereof |
| EP2681216B1 (en) * | 2011-02-28 | 2017-09-27 | Epizyme, Inc. | Substituted 6,5-fused bicyclic heteroaryl compounds |
| JO3438B1 (en) | 2011-04-13 | 2019-10-20 | Epizyme Inc | Aryl- or heteroaryl-substituted benzene compounds |
| TW201733984A (en) * | 2011-04-13 | 2017-10-01 | 雅酶股份有限公司 | Substituted benzene compounds |
| WO2013049770A2 (en) | 2011-09-30 | 2013-04-04 | Glaxosmithkline Llc | Methods of treating cancer |
| US9562041B2 (en) | 2012-05-16 | 2017-02-07 | Glaxosmithkline Llc | Enhancer of zeste homolog 2 inhibitors |
| WO2014049488A1 (en) | 2012-09-28 | 2014-04-03 | Pfizer Inc. | Benzamide and heterobenzamide compounds |
| LT3067358T (en) | 2012-12-21 | 2019-11-25 | Gilead Sciences Inc | Polycyclic-carbamoylpyridone compounds and their pharmaceutical use |
| UA116553C2 (en) | 2012-12-21 | 2018-04-10 | Санофі | Functionalized exendin-4 derivatives |
| ME03000B (en) | 2012-12-21 | 2018-10-20 | Plexxikon Inc | Compounds and methods for kinase modulation, and indications therefor |
| NZ708175A (en) | 2012-12-21 | 2020-06-26 | Hoffmann La Roche | Peptides as oxytocin agonists |
| FR3000059A1 (en) | 2012-12-21 | 2014-06-27 | Saint Gobain Placo | COMPOSITION FOR PLASTER PLATES AND PRODUCTS OBTAINED |
| UA111305C2 (en) | 2012-12-21 | 2016-04-11 | Пфайзер Інк. | Condensed with lactams of aryl and heteroaryl |
| US9233974B2 (en) | 2012-12-21 | 2016-01-12 | Gilead Sciences, Inc. | Antiviral compounds |
| KR102024417B1 (en) | 2012-12-21 | 2019-11-07 | 에피자임, 인코포레이티드 | Tetrahydro- and dihydro-isoquinoline prmt5 inhibitors and uses thereof |
| CN110684067A (en) | 2012-12-21 | 2020-01-14 | 艾丽奥斯生物制药有限公司 | Substituted nucleosides and nucleotides |
| FR3000065A1 (en) | 2012-12-21 | 2014-06-27 | Univ Lille Ii Droit & Sante | BICYCLIC COMPOUNDS HAVING ACTIVITY POTENTIATING THE ACTIVITY OF AN ACTIVE ANTIBIOTIC AGAINST MYCOBACTERIA-PHARMACEUTICAL COMPOSITION AND PRODUCT COMPRISING SUCH COMPOUNDS |
| ES2721031T3 (en) | 2014-06-17 | 2019-07-26 | Pfizer | Dihydroisoquinolinone substituted compounds |
-
2013
- 2013-05-12 UA UAA201505087A patent/UA111305C2/en unknown
- 2013-12-05 EA EA201590879A patent/EA028317B1/en unknown
- 2013-12-05 ES ES17206218T patent/ES2808987T3/en active Active
- 2013-12-05 RS RS20200917A patent/RS60582B9/en unknown
- 2013-12-05 ME MEP-2020-147A patent/ME03793B/en unknown
- 2013-12-05 PL PL13817739T patent/PL2935238T3/en unknown
- 2013-12-05 EP EP13817739.9A patent/EP2935238B1/en active Active
- 2013-12-05 EP EP17206218.4A patent/EP3339303B9/en active Active
- 2013-12-05 PE PE2015001044A patent/PE20151090A1/en active IP Right Grant
- 2013-12-05 LT LTEP17206218.4T patent/LT3339303T/en unknown
- 2013-12-05 MY MYPI2015701733A patent/MY176307A/en unknown
- 2013-12-05 MD MDA20150052A patent/MD4664C9/en not_active IP Right Cessation
- 2013-12-05 CR CR20200273A patent/CR20200273A/en unknown
- 2013-12-05 HU HUE13817739A patent/HUE038238T2/en unknown
- 2013-12-05 GE GEAP201313863A patent/GEP201706718B/en unknown
- 2013-12-05 SI SI201330958T patent/SI2935238T1/en unknown
- 2013-12-05 LT LTEP13817739.9T patent/LT2935238T/en unknown
- 2013-12-05 SI SI201331756T patent/SI3339303T1/en unknown
- 2013-12-05 MY MYPI2020003405A patent/MY192259A/en unknown
- 2013-12-05 WO PCT/IB2013/060682 patent/WO2014097041A1/en active Application Filing
- 2013-12-05 AP AP2015008574A patent/AP2015008574A0/en unknown
- 2013-12-05 JP JP2015548808A patent/JP5909308B2/en active Active
- 2013-12-05 MX MX2015008058A patent/MX2015008058A/en active IP Right Grant
- 2013-12-05 RS RS20180103A patent/RS56815B1/en unknown
- 2013-12-05 KR KR1020157019806A patent/KR101712441B1/en active IP Right Grant
- 2013-12-05 DK DK13817739.9T patent/DK2935238T3/en active
- 2013-12-05 ES ES13817739.9T patent/ES2658974T3/en active Active
- 2013-12-05 NZ NZ708801A patent/NZ708801A/en not_active IP Right Cessation
- 2013-12-05 CA CA2893339A patent/CA2893339C/en active Active
- 2013-12-05 PL PL17206218T patent/PL3339303T3/en unknown
- 2013-12-05 CU CU2015000062A patent/CU24414B1/en unknown
- 2013-12-05 BR BR112015014678-3A patent/BR112015014678B1/en not_active IP Right Cessation
- 2013-12-05 AU AU2013365908A patent/AU2013365908C1/en not_active Ceased
- 2013-12-05 HU HUE17206218A patent/HUE050009T2/en unknown
- 2013-12-05 CN CN201380066782.2A patent/CN104870435B/en not_active Expired - Fee Related
- 2013-12-05 SG SG11201504076XA patent/SG11201504076XA/en unknown
- 2013-12-05 PT PT172062184T patent/PT3339303T/en unknown
- 2013-12-05 DK DK17206218.4T patent/DK3339303T3/en active
- 2013-12-05 TR TR2018/02791T patent/TR201802791T4/en unknown
- 2013-12-05 PT PT138177399T patent/PT2935238T/en unknown
- 2013-12-05 MA MA38175A patent/MA38175B1/en unknown
- 2013-12-18 US US14/132,567 patent/US9040515B2/en active Active
- 2013-12-18 TW TW102146910A patent/TWI546293B/en not_active IP Right Cessation
- 2013-12-19 AR ARP130104902A patent/AR094174A1/en not_active Application Discontinuation
- 2013-12-20 UY UY0001038712A patent/UY38712A/en not_active Application Discontinuation
- 2013-12-20 UY UY0001035225A patent/UY35225A/en not_active Application Discontinuation
-
2014
- 2014-02-28 NO NO14709442A patent/NO2961649T3/no unknown
-
2015
- 2015-03-09 US US14/642,274 patent/US20150175572A1/en not_active Abandoned
- 2015-05-26 CR CR20150279A patent/CR20150279A/en unknown
- 2015-06-16 PH PH12015501367A patent/PH12015501367B1/en unknown
- 2015-06-18 IL IL239520A patent/IL239520B/en active IP Right Grant
- 2015-06-18 CL CL2015001733A patent/CL2015001733A1/en unknown
- 2015-06-18 TN TNP2015000281A patent/TN2015000281A1/en unknown
- 2015-06-19 DO DO2015000157A patent/DOP2015000157A/en unknown
- 2015-06-19 ZA ZA2015/04437A patent/ZA201504437B/en unknown
- 2015-06-19 GT GT201500190A patent/GT201500190A/en unknown
- 2015-06-19 MX MX2020002924A patent/MX2020002924A/en unknown
- 2015-07-21 EC ECIEPI201531579A patent/ECSP15031579A/en unknown
- 2015-09-30 HK HK15109626.6A patent/HK1208866A1/en not_active IP Right Cessation
-
2017
- 2017-05-03 US US15/585,880 patent/US10246433B2/en active Active
-
2018
- 2018-01-15 HR HRP20180060TT patent/HRP20180060T1/en unknown
- 2018-02-05 CY CY20181100137T patent/CY1119883T1/en unknown
- 2018-09-05 ME MEP-2018-8A patent/ME02980B/en unknown
-
2020
- 2020-07-30 HR HRP20201194TT patent/HRP20201194T2/en unknown
- 2020-08-11 CY CY20201100746T patent/CY1123237T1/en unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HRP20201194T1 (en) | Aryl and heteroaryl fused lactams | |
| HK1206740A1 (en) | Substituted hetero azepinones | |
| EP2862853A4 (en) | Fused heterocyclic compound | |
| EP2865671A4 (en) | Fused heterocyclic compound | |
| EP2857396A4 (en) | Fused heterocyclic compound | |
| EP2857397A4 (en) | Fused heterocyclic compound | |
| EP2884134A4 (en) | Thermoregulator | |
| EP2877854A4 (en) | Fusion proteins and methods thereof | |
| SG11201500927YA (en) | Kimono | |
| EP2865672A4 (en) | Fused heterocyclic compound | |
| AP2015008433A0 (en) | Heteroaryl derivatives and uses thereof | |
| HK1216017A1 (en) | Diazole lactams | |
| SG11201403852UA (en) | Fused pyrroledicarboxamides and their use as pharmaceuticals | |
| EP2820499A4 (en) | Programmable sensors | |
| AU4710P (en) | Fusion xTriticosecale | |
| GB201215901D0 (en) | Protein modification |