SG11201405691WA - Solid forms of an epidermal growth factor receptor kinase inhibitor - Google Patents

Solid forms of an epidermal growth factor receptor kinase inhibitor

Info

Publication number
SG11201405691WA
SG11201405691WA SG11201405691WA SG11201405691WA SG11201405691WA SG 11201405691W A SG11201405691W A SG 11201405691WA SG 11201405691W A SG11201405691W A SG 11201405691WA SG 11201405691W A SG11201405691W A SG 11201405691WA SG 11201405691W A SG11201405691W A SG 11201405691WA
Authority
SG
Singapore
Prior art keywords
growth factor
kinase inhibitor
factor receptor
epidermal growth
solid forms
Prior art date
Application number
SG11201405691WA
Inventor
Mei Lai
Original Assignee
Celgene Avilomics Res Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Avilomics Res Inc filed Critical Celgene Avilomics Res Inc
Publication of SG11201405691WA publication Critical patent/SG11201405691WA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
SG11201405691WA 2012-03-15 2013-03-13 Solid forms of an epidermal growth factor receptor kinase inhibitor SG11201405691WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261611376P 2012-03-15 2012-03-15
PCT/US2013/030982 WO2013138495A1 (en) 2012-03-15 2013-03-13 Solid forms of an epidermal growth factor receptor kinase inhibitor

Publications (1)

Publication Number Publication Date
SG11201405691WA true SG11201405691WA (en) 2014-10-30

Family

ID=49161778

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201405691WA SG11201405691WA (en) 2012-03-15 2013-03-13 Solid forms of an epidermal growth factor receptor kinase inhibitor
SG10201700804XA SG10201700804XA (en) 2012-03-15 2013-03-13 Solid forms of an epidermal growth factor receptor kinase inhibitor

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201700804XA SG10201700804XA (en) 2012-03-15 2013-03-13 Solid forms of an epidermal growth factor receptor kinase inhibitor

Country Status (18)

Country Link
US (5) US9056839B2 (en)
EP (1) EP2825041B1 (en)
JP (2) JP6317319B2 (en)
KR (1) KR102081042B1 (en)
CN (2) CN104302178B (en)
AU (2) AU2016203338A1 (en)
BR (1) BR112014022789B1 (en)
CA (1) CA2866852C (en)
ES (1) ES2880109T3 (en)
HK (1) HK1205431A1 (en)
IL (1) IL234425B (en)
IN (1) IN2014DN07401A (en)
MX (1) MX356753B (en)
MY (1) MY169233A (en)
RU (1) RU2673077C2 (en)
SG (2) SG11201405691WA (en)
WO (1) WO2013138495A1 (en)
ZA (1) ZA201407441B (en)

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WO2016101912A1 (en) * 2014-12-25 2016-06-30 苏州晶云药物科技有限公司 Crystal form of salt of epidermal growth factor receptor kinase inhibitor and preparation method thereof
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CN107663207B (en) * 2016-07-27 2021-07-30 南京圣和药业股份有限公司 Mesylate crystal of EGFR kinase inhibitor and preparation method thereof
CN107955019B (en) * 2016-10-17 2021-09-14 广东众生药业股份有限公司 Salt form and crystal form of EGFR inhibitor and preparation method thereof
CN108299419B (en) * 2017-01-11 2022-04-26 南京圣和药业股份有限公司 Novel crystal forms of novel EGFR kinase inhibitor and preparation method thereof
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