SG11201401640QA - IMPROVED METHOD FOR PRODUCTION OF F-18 LABELED Aß LIGANDS - Google Patents

IMPROVED METHOD FOR PRODUCTION OF F-18 LABELED Aß LIGANDS

Info

Publication number
SG11201401640QA
SG11201401640QA SG11201401640QA SG11201401640QA SG11201401640QA SG 11201401640Q A SG11201401640Q A SG 11201401640QA SG 11201401640Q A SG11201401640Q A SG 11201401640QA SG 11201401640Q A SG11201401640Q A SG 11201401640QA SG 11201401640Q A SG11201401640Q A SG 11201401640QA
Authority
SG
Singapore
Prior art keywords
ligands
labeled
production
improved method
improved
Prior art date
Application number
SG11201401640QA
Inventor
Franz Meier
Keith Graham
Original Assignee
Piramal Imaging Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Piramal Imaging Sa filed Critical Piramal Imaging Sa
Publication of SG11201401640QA publication Critical patent/SG11201401640QA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/64One oxygen atom attached in position 2 or 6
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C07D213/16Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
    • C07D213/18Salts thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05Isotopically modified compounds, e.g. labelled

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
SG11201401640QA 2011-10-19 2012-10-18 IMPROVED METHOD FOR PRODUCTION OF F-18 LABELED Aß LIGANDS SG11201401640QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11075236 2011-10-19
PCT/EP2012/070669 WO2013057199A1 (en) 2011-10-19 2012-10-18 IMPROVED METHOD FOR PRODUCTION OF F-18 LABELED Aß LIGANDS

Publications (1)

Publication Number Publication Date
SG11201401640QA true SG11201401640QA (en) 2014-07-30

Family

ID=47022716

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201401640QA SG11201401640QA (en) 2011-10-19 2012-10-18 IMPROVED METHOD FOR PRODUCTION OF F-18 LABELED Aß LIGANDS

Country Status (11)

Country Link
US (1) US20140243533A1 (en)
EP (1) EP2768790A1 (en)
JP (1) JP2015501305A (en)
AU (1) AU2012324940A1 (en)
BR (1) BR112014009013A2 (en)
CA (1) CA2852840A1 (en)
IL (1) IL231964A0 (en)
IN (1) IN2014MN00875A (en)
MX (1) MX2014004274A (en)
SG (1) SG11201401640QA (en)
WO (1) WO2013057199A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116794184B (en) * 2023-06-26 2024-02-09 天津键凯科技有限公司 Method for detecting polyethylene glycol with single polymerization degree and homologous impurities

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100789847B1 (en) 2004-12-15 2007-12-28 (주)퓨쳐켐 A Preparation Method of Organo Fluoro Compounds in Alcohol Solvents
SI2213652T1 (en) 2004-12-17 2015-03-31 The Trustees Of The University Of Pennsylvania Stilbene derivatives and their use for binding and imaging amyloid plaques
NZ570887A (en) 2006-03-30 2011-05-27 Univ Pennsylvania Styrylpyridine derivatives and their use for binding and imaging amyloid plaques
PL2381967T3 (en) 2008-12-31 2017-06-30 Avid Radiopharmaceuticals, Inc. Synthesis of 18f-radiolabeled styrylpyridines from tosylate precursors and stable pharmaceutical compositions thereof
EP2575900A1 (en) * 2010-06-04 2013-04-10 Piramal Imaging SA Method for production of f-18 labeled amyloid beta ligands
EA022897B1 (en) * 2010-06-04 2016-03-31 Пирамаль Имэджинг Са METHOD FOR PRODUCTION OF F-18 LABELED Aβ LIGANDS
TWI504414B (en) * 2010-06-04 2015-10-21 Bayer Schering Pharma Ag Method for production of f-18 labeled aβ ligands
EP2575898B8 (en) * 2010-06-04 2021-04-21 Life Molecular Imaging SA Method for production of f-18 labeled amyloid beta ligand
KR20140006783A (en) * 2010-09-09 2014-01-16 피라말 이미징 에스에이 Method for rapid preparation of suitable [18f]fluoride for nucleophilic [18f]fluorination
CN108218650A (en) * 2010-12-29 2018-06-29 通用电气健康护理有限公司 Elute solution

Also Published As

Publication number Publication date
US20140243533A1 (en) 2014-08-28
MX2014004274A (en) 2014-07-09
IL231964A0 (en) 2014-05-28
EP2768790A1 (en) 2014-08-27
JP2015501305A (en) 2015-01-15
AU2012324940A1 (en) 2014-04-17
CA2852840A1 (en) 2013-04-25
IN2014MN00875A (en) 2015-04-17
BR112014009013A2 (en) 2017-05-02
WO2013057199A1 (en) 2013-04-25

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