SG10202004779XA - Production of carotenoids and apocarotenoids - Google Patents
Production of carotenoids and apocarotenoidsInfo
- Publication number
- SG10202004779XA SG10202004779XA SG10202004779XA SG10202004779XA SG10202004779XA SG 10202004779X A SG10202004779X A SG 10202004779XA SG 10202004779X A SG10202004779X A SG 10202004779XA SG 10202004779X A SG10202004779X A SG 10202004779XA SG 10202004779X A SG10202004779X A SG 10202004779XA
- Authority
- SG
- Singapore
- Prior art keywords
- apocarotenoids
- carotenoids
- production
- Prior art date
Links
- 229930003362 apo carotenoid Natural products 0.000 title 1
- 125000000135 apo carotenoid group Chemical group 0.000 title 1
- 235000021466 carotenoid Nutrition 0.000 title 1
- 150000001747 carotenoids Chemical class 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0069—Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
- C12P5/026—Unsaturated compounds, i.e. alkenes, alkynes or allenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
- C12P7/26—Ketones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y113/00—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13)
- C12Y113/11—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13) with incorporation of two atoms of oxygen (1.13.11)
- C12Y113/11051—9-Cis-epoxycarotenoid dioxygenase (1.13.11.51)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y113/00—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13)
- C12Y113/11—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13) with incorporation of two atoms of oxygen (1.13.11)
- C12Y113/11063—Beta-carotene 15,15'-dioxygenase (1.13.11.63)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y113/00—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13)
- C12Y113/11—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13) with incorporation of two atoms of oxygen (1.13.11)
- C12Y113/11068—9-Cis-beta-carotene 9',10'-cleaving dioxygenase (1.13.11.68)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y505/00—Intramolecular lyases (5.5)
- C12Y505/01—Intramolecular lyases (5.5.1)
- C12Y505/01018—Lycopene epsilon-cyclase (5.5.1.18)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y505/00—Intramolecular lyases (5.5)
- C12Y505/01—Intramolecular lyases (5.5.1)
- C12Y505/01019—Lycopene beta-cyclase (5.5.1.19)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SG10201701500U | 2017-02-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10202004779XA true SG10202004779XA (en) | 2020-06-29 |
Family
ID=63252286
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10202004779XA SG10202004779XA (en) | 2017-02-24 | 2018-02-26 | Production of carotenoids and apocarotenoids |
| SG11201907812TA SG11201907812TA (en) | 2017-02-24 | 2018-02-26 | Production of carotenoids and apocarotenoids |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201907812TA SG11201907812TA (en) | 2017-02-24 | 2018-02-26 | Production of carotenoids and apocarotenoids |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US11920137B2 (de) |
| EP (2) | EP3585903B1 (de) |
| CN (2) | CN110546268B (de) |
| SG (2) | SG10202004779XA (de) |
| WO (1) | WO2018156086A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019126777A1 (en) * | 2017-12-21 | 2019-06-27 | Advanced Biotech Inc. | Production of (r)-(e)-(+)-alpha-ionone in recombinant saccharomyces cerevisiae |
| CN111100849B (zh) * | 2020-01-16 | 2021-01-12 | 安徽农业大学 | 茶树类胡萝卜素裂解双加氧酶CsCCD4及其在催化合成β-紫罗酮上的应用 |
| CN115426874A (zh) * | 2020-04-21 | 2022-12-02 | 日本烟草产业株式会社 | 烟草植物体及其制备方法 |
| WO2022245301A2 (en) * | 2021-05-21 | 2022-11-24 | Agency For Science, Technology And Research | De novo biosynthesis of glycosylated carotenoids |
| CN113549639B (zh) * | 2021-07-21 | 2022-07-29 | 云南中烟工业有限责任公司 | 一种降低烟叶总蛋白及烟气苯酚含量的调控基因 |
| WO2023167638A2 (en) * | 2022-03-01 | 2023-09-07 | Agency For Science, Technology And Research | Biosynthesis of apocarotenoids by controlling oxidative stress |
| WO2024163976A1 (en) * | 2023-02-03 | 2024-08-08 | Amyris, Inc. | Host cells capable of producing retinol or retinol precursors and methods of use thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7252964B2 (en) | 2001-06-12 | 2007-08-07 | Institut De Recherche Pour Le Developpement (I.R.D.) | Isolated carotenoid biosynthesis gene cluster involved in canthaxanthin production and applications thereof |
| US20040219629A1 (en) | 2002-12-19 | 2004-11-04 | Qiong Cheng | Increasing carotenoid production in bacteria via chromosomal integration |
| AU2006287233A1 (en) * | 2005-09-02 | 2007-03-08 | Cornell University | Polynucleotides encoding carotenoid and apocarotenoid biosynthetic pathway |
| GB0524873D0 (en) | 2005-12-06 | 2006-01-11 | New Royal Holloway & Bedford | Bacterial production of carotenoids |
| WO2016154314A1 (en) * | 2015-03-23 | 2016-09-29 | Arch Innotek, Llc | Compositions and methods of biosynthesizing carotenoids and their derivatives |
| US11326173B2 (en) | 2015-08-28 | 2022-05-10 | Phytowelt Greentechnologies Gmbh | Method of fermentative alpha-ionone production |
-
2018
- 2018-02-26 CN CN201880026537.1A patent/CN110546268B/zh active Active
- 2018-02-26 CN CN202311292626.XA patent/CN117143951A/zh active Pending
- 2018-02-26 WO PCT/SG2018/050087 patent/WO2018156086A1/en unknown
- 2018-02-26 SG SG10202004779XA patent/SG10202004779XA/en unknown
- 2018-02-26 EP EP18758451.1A patent/EP3585903B1/de active Active
- 2018-02-26 EP EP24165181.9A patent/EP4403627A2/de active Pending
- 2018-02-26 SG SG11201907812TA patent/SG11201907812TA/en unknown
- 2018-02-26 US US16/488,504 patent/US11920137B2/en active Active
-
2023
- 2023-10-26 US US18/384,044 patent/US20240175036A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2018156086A1 (en) | 2018-08-30 |
| CN110546268A (zh) | 2019-12-06 |
| SG11201907812TA (en) | 2019-09-27 |
| US11920137B2 (en) | 2024-03-05 |
| EP3585903C0 (de) | 2024-04-17 |
| EP3585903B1 (de) | 2024-04-17 |
| CN117143951A (zh) | 2023-12-01 |
| EP3585903A1 (de) | 2020-01-01 |
| EP4403627A2 (de) | 2024-07-24 |
| US20190367928A1 (en) | 2019-12-05 |
| EP3585903A4 (de) | 2021-05-19 |
| US20240175036A1 (en) | 2024-05-30 |
| CN110546268B (zh) | 2023-10-20 |
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