SG10201913487RA - Peptide with anti-obesity and anti-diabetes activity and use thereof - Google Patents

Peptide with anti-obesity and anti-diabetes activity and use thereof

Info

Publication number
SG10201913487RA
SG10201913487RA SG10201913487RA SG10201913487RA SG10201913487RA SG 10201913487R A SG10201913487R A SG 10201913487RA SG 10201913487R A SG10201913487R A SG 10201913487RA SG 10201913487R A SG10201913487R A SG 10201913487RA SG 10201913487R A SG10201913487R A SG 10201913487RA
Authority
SG
Singapore
Prior art keywords
obesity
peptide
diabetes activity
diabetes
activity
Prior art date
Application number
SG10201913487RA
Inventor
Yong Ji Chung
Eun Mi Kim
Original Assignee
Caregen Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Caregen Co Ltd filed Critical Caregen Co Ltd
Publication of SG10201913487RA publication Critical patent/SG10201913487RA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/2264Obesity-gene products, e.g. leptin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/30Insulin-like growth factors (Somatomedins), e.g. IGF-1, IGF-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/5759Products of obesity genes, e.g. leptin, obese (OB), tub, fat
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
SG10201913487RA 2015-04-28 2015-05-12 Peptide with anti-obesity and anti-diabetes activity and use thereof SG10201913487RA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020150059648A KR101669140B1 (en) 2015-04-28 2015-04-28 Peptides having Anti-obesity and Anti-Diabetes Effects and Use Thereof

Publications (1)

Publication Number Publication Date
SG10201913487RA true SG10201913487RA (en) 2020-02-27

Family

ID=57198486

Family Applications (4)

Application Number Title Priority Date Filing Date
SG10201913487RA SG10201913487RA (en) 2015-04-28 2015-05-12 Peptide with anti-obesity and anti-diabetes activity and use thereof
SG10201913489UA SG10201913489UA (en) 2015-04-28 2015-05-12 Peptide with anti-obesity and anti-diabetes activity and use thereof
SG11201708847VA SG11201708847VA (en) 2015-04-28 2015-05-12 Peptide with anti-obesity and anti-diabetes activity and use thereof
SG10201913490WA SG10201913490WA (en) 2015-04-28 2015-05-12 Peptide with anti-obesity and anti-diabetes activity and use thereof

Family Applications After (3)

Application Number Title Priority Date Filing Date
SG10201913489UA SG10201913489UA (en) 2015-04-28 2015-05-12 Peptide with anti-obesity and anti-diabetes activity and use thereof
SG11201708847VA SG11201708847VA (en) 2015-04-28 2015-05-12 Peptide with anti-obesity and anti-diabetes activity and use thereof
SG10201913490WA SG10201913490WA (en) 2015-04-28 2015-05-12 Peptide with anti-obesity and anti-diabetes activity and use thereof

Country Status (22)

Country Link
US (4) US10351597B2 (en)
EP (4) EP3613760B1 (en)
JP (4) JP6606192B2 (en)
KR (1) KR101669140B1 (en)
CN (3) CN106459152B (en)
AU (4) AU2015393357B2 (en)
BR (4) BR122020019171B1 (en)
CA (4) CA3074790C (en)
CL (4) CL2017002718A1 (en)
CO (1) CO2017011998A2 (en)
EA (1) EA037799B1 (en)
ES (4) ES2831329T3 (en)
HK (1) HK1252251A1 (en)
IL (4) IL255263B (en)
MX (4) MX2020012992A (en)
MY (4) MY192154A (en)
NZ (4) NZ747392A (en)
PH (1) PH12017501983B1 (en)
SA (4) SA520420881B1 (en)
SG (4) SG10201913487RA (en)
WO (1) WO2016175362A1 (en)
ZA (1) ZA201708044B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101669140B1 (en) 2015-04-28 2016-10-26 (주)케어젠 Peptides having Anti-obesity and Anti-Diabetes Effects and Use Thereof
KR101831888B1 (en) * 2016-04-15 2018-04-16 (주)케어젠 Peptides Having Activities for Anti-inflammation and Uses Thereof
KR101887576B1 (en) 2016-04-15 2018-08-13 (주)케어젠 Peptides having Anti-obesity and Anti-Diabetes Effects and Use Thereof
KR101955511B1 (en) * 2016-08-17 2019-03-11 (주)진셀팜 Peptide having lipolysis promoting effect, and uses thereof
KR101887577B1 (en) * 2016-10-19 2018-09-10 (주)케어젠 Peptides having Anti-obesity and Anti-Diabetes Effects and Use Thereof
KR102386705B1 (en) * 2016-11-07 2022-04-21 주식회사 삼양사 marker gene related with anti-adipogenic activity of allulose and use thereof
CN106518971B (en) * 2016-12-05 2019-12-10 华南理工大学 Anti-obesity decapeptide CANPHELPNK
CN106749533B (en) * 2016-12-05 2020-08-18 华南理工大学 Anti-obesity heptadecapeptide LNNPSVCDCDCMMKAAR
CN106699846B (en) * 2016-12-05 2020-08-18 华南理工大学 Anti-obesity undecapeptide NALKCCHSCPA
CN106749524B (en) * 2016-12-05 2020-08-18 华南理工大学 Anti-obesity heptapeptide NPVWKRK
JP7133982B2 (en) * 2017-08-10 2022-09-09 小林製薬株式会社 tablet composition
KR101920047B1 (en) 2018-01-03 2018-11-19 (주)케어젠 Peptides having Anti-obesity and Anti-Diabetes Effects and Use Thereof
KR102065150B1 (en) 2018-04-27 2020-01-10 (주)케어젠 A composition for preventing or treating obesity comprising isotretinoin-peptide conjugate as an effective ingredient
KR102171141B1 (en) * 2018-05-28 2020-10-28 중앙대학교 산학협력단 Composition for preventing, treating, or improving obesity comprising the peptides derived from LGI3 as the active ingredients
CN108676073B (en) * 2018-06-07 2021-10-26 华南理工大学 Anti-obesity decapeptide LLVVYPWTQR and application thereof
CN109081862A (en) * 2018-06-07 2018-12-25 华南理工大学 The anti-obesity tetrapeptide PQTR of one kind and its application
CN112010941B (en) * 2019-05-31 2022-08-16 华南理工大学 Blood sugar reducing heptapeptide
CN113248628B (en) * 2021-07-13 2021-10-22 南京市妇幼保健院 Milk-derived polypeptide derivative and application thereof in preparation of obesity prevention and treatment medicines, health-care products and food additives
KR20230046870A (en) * 2021-09-30 2023-04-06 (주)케어젠 Peptide Having Anti-Obesity and Uses Thereof
KR20230138832A (en) 2022-03-24 2023-10-05 (주)케어젠 Peptide Complex Having Activity of Anti-Diabetes and Uses Thereof
KR20230148629A (en) 2022-04-18 2023-10-25 (주)케어젠 Peptide Having Activity of Anti-Obesity and Anti-Diabetes and Uses Thereof

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6723699B1 (en) 1989-06-05 2004-04-20 Cephalon, Inc. Treating disorders by application of insulin-like growth factors and analogs
US6693076B1 (en) * 1989-06-05 2004-02-17 Cephalon, Inc. Treating disorders by application of insulin-like growth factors and analogs
US6310040B1 (en) * 1991-11-08 2001-10-30 Cephalon, Inc. Treating retinal neuronal disorders by the application of insulin-like growth factors and analogs
US5516891A (en) 1992-06-16 1996-05-14 Kinerton, Ltd. Liquid phase synthesis of peptides and peptide derivatives
GB9217696D0 (en) * 1992-08-20 1992-09-30 Agricultural & Food Res Use of specific binding molecules
PT1975177E (en) * 1996-03-01 2011-07-26 Novo Nordisk As An appetite-suppressing peptide, its compositions and use
US6087334A (en) * 1998-08-21 2000-07-11 Amylin Pharmaceuticals, Inc. Anti-diabetic peptides
US20020132767A1 (en) 2000-01-31 2002-09-19 Rosen Craig A. Nucleic acids, proteins, and antibodies
DE60113380T2 (en) * 2000-02-18 2006-06-29 Leangene Ab METHODS FOR IDENTIFYING COMPOSITIONS USEFUL FOR TREATMENT OF FAT ADJUSTMENT USING FOXC2
WO2001092523A2 (en) 2000-05-30 2001-12-06 Curagen Corporation Human polynucleotides and polypeptides encoded thereby
EP1998266A3 (en) 2001-02-19 2009-02-11 Merck Patent GmbH Method for identification of T-cell epitopes and use for preparing molecules with reduced immunogenicity
CA2388287A1 (en) * 2001-05-30 2002-11-30 Terry E. Graham Therapies for the prevention and treatment of diabetes and obesity
US7041646B2 (en) * 2001-10-05 2006-05-09 Bayer Pharmaceuticals Corporation Methods of treating type 2 diabetes with peptides acting as both GLP-1 receptor agonists and glucagon receptor antagonists
CA2473781A1 (en) 2002-01-18 2003-07-31 Protemix Corporation Limited Glycoisoforms of adiponectin and uses thereof
US20050143297A1 (en) 2003-05-26 2005-06-30 Jean-Pierre Rosat Method for the administration of ligands, agonists of ligands of the TNF family with reduced toxicity
CN1980686A (en) * 2004-04-05 2007-06-13 安斯泰来制药有限公司 Antiobesity drug
US20070185025A1 (en) * 2005-09-11 2007-08-09 The Trustees Of Columbia University In The City Of New York Filoviral immunosuppressive peptides and uses thereof
WO2007087468A2 (en) * 2006-01-09 2007-08-02 Children's Hospital Medical Center Adiponectin for treatment of various disorders
JP4971373B2 (en) 2006-03-06 2012-07-11 ケアジェン シーオー エルティーディー Peptide having insulin-like growth factor-1 activity and use thereof
BRPI0712052A2 (en) 2006-06-09 2012-01-10 Novartis Ag stabilized insulin-like growth factor polypeptides
CN101091765A (en) * 2007-06-08 2007-12-26 余仁生国际有限公司 Medicinal comsns-and usage for preventing and treating diabets mellitus
KR101050429B1 (en) * 2009-03-18 2011-07-19 연세대학교 산학협력단 Composition for the prevention or treatment of obesity, dyslipidemia, fatty liver or insulin resistance syndrome comprising camphor as an active ingredient
CN103402536A (en) * 2010-12-22 2013-11-20 马克迪亚生物科技公司 Methods for treating metabolic disorders and obesity with GIP and GLP-1 receptor-active glucagon-based peptides
EP2505641B1 (en) * 2011-04-01 2015-04-15 F. Hoffmann-La Roche AG T7 RNA polymerase variants with Cysteine-Serine substitutions
KR101363455B1 (en) * 2011-09-09 2014-02-21 (주)케어젠 Peptides Inhibiting the Activity of Matrix Metalloproteases and Use Thereof
KR20140027594A (en) * 2012-07-23 2014-03-07 씨지케이바이오 주식회사 Pharmaceutical composition having anti-diabetic and anti-obesity activties
KR102101529B1 (en) 2012-09-21 2020-04-17 다우 글로벌 테크놀로지스 엘엘씨 Dye fixative agents and methods
JP6387008B2 (en) * 2012-09-26 2018-09-05 インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation Insulin analog dimer
KR101510742B1 (en) 2013-05-13 2015-04-10 (주)케어젠 Peptides for Inducing Mast Cell-Spepcific Apoptosis and Uses Thereof
US10471125B2 (en) 2014-03-13 2019-11-12 Universite Grenoble Alpes Pharmaceutical compositions and their use for the treatment of autoimmune disorders
KR101669140B1 (en) 2015-04-28 2016-10-26 (주)케어젠 Peptides having Anti-obesity and Anti-Diabetes Effects and Use Thereof

Also Published As

Publication number Publication date
ES2894638T3 (en) 2022-02-15
CA3074790C (en) 2023-01-31
PH12017501983A1 (en) 2018-03-19
PH12017501983B1 (en) 2018-03-19
EP3290434A1 (en) 2018-03-07
CA3074800C (en) 2022-04-12
CA3074836A1 (en) 2016-11-03
EP3290434A4 (en) 2018-08-15
CN110172083A (en) 2019-08-27
BR122020019077B1 (en) 2023-11-07
US20190270773A1 (en) 2019-09-05
KR101669140B1 (en) 2016-10-26
JP6908085B2 (en) 2021-07-21
BR122020019095B1 (en) 2023-11-14
SG10201913490WA (en) 2020-03-30
EP3613760B1 (en) 2021-07-28
JP2020007371A (en) 2020-01-16
CA3074800A1 (en) 2016-11-03
CA2984287C (en) 2021-01-19
BR112017023199B1 (en) 2023-11-07
NZ747396A (en) 2020-10-30
AU2019203655B2 (en) 2020-07-02
CL2017002718A1 (en) 2018-11-09
SG11201708847VA (en) 2017-11-29
SA520420881B1 (en) 2023-01-15
MY197888A (en) 2023-07-23
ZA201708044B (en) 2022-09-28
NZ747392A (en) 2020-08-28
JP6813155B2 (en) 2021-01-13
US20190270774A1 (en) 2019-09-05
CL2019002960A1 (en) 2020-02-21
US10351597B2 (en) 2019-07-16
JP6813156B2 (en) 2021-01-13
IL282513A (en) 2021-06-30
EP3290434B1 (en) 2020-08-19
EP3613760A1 (en) 2020-02-26
JP2018515471A (en) 2018-06-14
CA3074790A1 (en) 2016-11-03
CA2984287A1 (en) 2016-11-03
US10738081B2 (en) 2020-08-11
MX2017013847A (en) 2018-06-15
NZ747390A (en) 2020-08-28
EA037799B1 (en) 2021-05-21
NZ737077A (en) 2019-05-31
MX2020012994A (en) 2022-10-13
IL255263A (en) 2018-04-30
IL282514B (en) 2022-01-01
HK1252251A1 (en) 2019-05-24
EP3613758A1 (en) 2020-02-26
SG10201913489UA (en) 2020-02-27
US20180118783A1 (en) 2018-05-03
CN110105432B (en) 2022-12-27
CL2019002959A1 (en) 2020-02-21
US11186611B2 (en) 2021-11-30
JP6606192B2 (en) 2019-11-13
WO2016175362A1 (en) 2016-11-03
BR122020019171B1 (en) 2023-11-07
JP2020007373A (en) 2020-01-16
CN110105432A (en) 2019-08-09
MY197887A (en) 2023-07-23
SA517390237B1 (en) 2021-03-17
US20190270772A1 (en) 2019-09-05
EA201792365A1 (en) 2018-04-30
CA3074836C (en) 2021-06-15
AU2015393357A1 (en) 2017-11-30
AU2019203659B2 (en) 2020-07-02
EP3613758B1 (en) 2021-07-21
IL282510B (en) 2022-01-01
IL282514A (en) 2021-06-30
EP3613759B1 (en) 2021-07-21
MY197886A (en) 2023-07-23
ES2831329T3 (en) 2021-06-08
IL255263B (en) 2022-02-01
SA520420880B1 (en) 2021-11-14
ES2895167T3 (en) 2022-02-17
IL282510A (en) 2021-06-30
AU2019203657B2 (en) 2020-07-02
MX2020012993A (en) 2022-10-13
MY192154A (en) 2022-08-02
ES2893468T3 (en) 2022-02-09
US10626145B2 (en) 2020-04-21
MX2020012992A (en) 2022-10-13
EP3613759A1 (en) 2020-02-26
AU2019203655A1 (en) 2019-06-13
AU2015393357B2 (en) 2019-05-16
SA520420882B1 (en) 2021-11-14
AU2019203657A1 (en) 2019-06-13
AU2019203659A1 (en) 2019-06-13
CO2017011998A2 (en) 2018-02-09
CN106459152A (en) 2017-02-22
BR112017023199A2 (en) 2019-01-29
CN106459152B (en) 2019-06-28
CL2019002958A1 (en) 2020-02-21
IL282513B (en) 2022-01-01
CN110172083B (en) 2022-12-30
JP2020007372A (en) 2020-01-16

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