SG10201903161XA - Methods for production and uses of multipotent cell populations - Google Patents
Methods for production and uses of multipotent cell populationsInfo
- Publication number
- SG10201903161XA SG10201903161XA SG10201903161XA SG10201903161XA SG10201903161XA SG 10201903161X A SG10201903161X A SG 10201903161XA SG 10201903161X A SG10201903161X A SG 10201903161XA SG 10201903161X A SG10201903161X A SG 10201903161XA SG 10201903161X A SG10201903161X A SG 10201903161XA
- Authority
- SG
- Singapore
- Prior art keywords
- methods
- cell populations
- production
- multipotent
- hiv
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
- C12N15/1132—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses against retroviridae, e.g. HIV
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
- C12N2310/111—Antisense spanning the whole gene, or a large part of it
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/13—Decoys
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
- C12N2320/31—Combination therapy
Abstract
Methods for production and uses of multipotent cell populations The claimed invention is directed towards the generation of pluripotent, multipotent, and/or self-renewing cells which are capable of beginning to differentiate in culture into a variety of cell types and capable of further differentiation in vivo. The claimed invention is also directed towards the generation of desirable, differentiating cell populations transplantable to patients, genetic modification of endogenous cells, and the treatment of patients suffering from diseases that may be ameliorated by these methods. This invention also provides methods for preventing, treating, or retarding disease related to immunodeficiency virus (e.g. HIV-I, HIV-2, SIV, FIV, etc.) infection. Drawing to accompany the abstract (for publication purposes): No Suitable Figure
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US93202007P | 2007-05-29 | 2007-05-29 | |
US93313307P | 2007-06-05 | 2007-06-05 | |
US93367007P | 2007-06-08 | 2007-06-08 | |
US644908P | 2008-01-14 | 2008-01-14 | |
US6476108P | 2008-03-25 | 2008-03-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201903161XA true SG10201903161XA (en) | 2019-05-30 |
Family
ID=40094346
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201509679XA SG10201509679XA (en) | 2007-05-29 | 2008-05-28 | Methods for production and uses of multipotent cell populations |
SG10201903161XA SG10201903161XA (en) | 2007-05-29 | 2008-05-28 | Methods for production and uses of multipotent cell populations |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201509679XA SG10201509679XA (en) | 2007-05-29 | 2008-05-28 | Methods for production and uses of multipotent cell populations |
Country Status (15)
Country | Link |
---|---|
US (1) | US20110217274A1 (en) |
EP (2) | EP3128015A3 (en) |
JP (2) | JP2010528613A (en) |
CN (2) | CN101772580B (en) |
AU (1) | AU2008260187A1 (en) |
BR (1) | BRPI0810949A2 (en) |
CA (1) | CA2725953A1 (en) |
ES (1) | ES2612538T3 (en) |
HU (1) | HUE030872T2 (en) |
IL (2) | IL202401A (en) |
PL (1) | PL2164993T3 (en) |
PT (1) | PT2164993T (en) |
RU (2) | RU2535365C2 (en) |
SG (2) | SG10201509679XA (en) |
WO (1) | WO2008150814A2 (en) |
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US8278104B2 (en) | 2005-12-13 | 2012-10-02 | Kyoto University | Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2 |
EP4223769A3 (en) | 2005-12-13 | 2023-11-01 | Kyoto University | Nuclear reprogramming factor |
EP2137296A2 (en) | 2007-03-23 | 2009-12-30 | Wisconsin Alumni Research Foundation | Somatic cell reprogramming |
US11859168B2 (en) * | 2007-05-29 | 2024-01-02 | Christopher B. REID | Electroporation, developmentally-activated cells, pluripotent-like cells, cell reprogramming and regenerative medicine |
US9213999B2 (en) | 2007-06-15 | 2015-12-15 | Kyoto University | Providing iPSCs to a customer |
JP2008307007A (en) | 2007-06-15 | 2008-12-25 | Bayer Schering Pharma Ag | Human pluripotent stem cell induced from human tissue-originated undifferentiated stem cell after birth |
JP5346925B2 (en) | 2008-05-02 | 2013-11-20 | 国立大学法人京都大学 | Nuclear initialization method |
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JP2010148440A (en) * | 2008-12-25 | 2010-07-08 | Japan Health Science Foundation | System for quickly constructing recombinant adenovirus |
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US9365866B2 (en) * | 2009-06-03 | 2016-06-14 | National Institute Of Advanced Industrial Science And Technology | Vectors for generating pluripotent stem cells and methods of producing pluripotent stem cells using the same |
US9453205B2 (en) * | 2009-10-31 | 2016-09-27 | Genesis Technologies Limited | Methods for reprogramming cells and uses thereof |
CN102947444A (en) * | 2010-06-23 | 2013-02-27 | 帷幄生物技术公司 | Compositions and methods for re-programming cells without genetic modification for treatment of cardiovascular diseases |
EP2625272B1 (en) | 2010-10-08 | 2015-09-16 | Mina Therapeutics Limited | Methods of inducing insulin production |
WO2012061075A2 (en) * | 2010-10-25 | 2012-05-10 | The Regents Of The University Of California | Hiv resistant and functional hematopoietic stem/progenitor cells and macrophages from induced pluripotent stem cells |
JP6073795B2 (en) * | 2010-10-27 | 2017-02-01 | カッパーアールエヌエー,インコーポレイテッド | Treatment of IFRD1-related diseases by inhibition of natural antisense transcripts to interferon-related developmental regulator 1 (IFRD1) |
JP6073916B2 (en) * | 2011-12-05 | 2017-02-01 | ファクター バイオサイエンス インコーポレイテッド | Methods and products for transfecting cells |
CN102659951A (en) * | 2012-05-29 | 2012-09-12 | 西安医学院 | TAT (Trans-activating factor) kringle domain-modified nenurogenin2 fusion protein, as well as preparation method thereof and application thereof |
WO2014035433A1 (en) * | 2012-08-31 | 2014-03-06 | Jan Nolta | Genetically modified msc and therapeutic methods |
US9663564B2 (en) | 2013-03-15 | 2017-05-30 | The Regents Of The University Of California | Vectors and methods to treat ischemia |
US20140065110A1 (en) | 2012-08-31 | 2014-03-06 | The Regents Of The University Of California | Genetically modified msc and therapeutic methods |
US20140271923A1 (en) | 2013-03-14 | 2014-09-18 | Christopher Brian Reid | Compositions & formulations for preventing and treating chronic diseases that cluster in patients such as cardiovascular disease, diabetes, obesity, polycystic ovary syndrome, hyperlipidemia and hypertension, as well as for preventing and treating other diseases and conditions |
CA2930973A1 (en) | 2013-11-22 | 2015-05-28 | Pal SAERTROM | C/ebp alpha short activating rna compositions and methods of use |
EP3268480B1 (en) * | 2015-03-09 | 2021-05-19 | Sinai Health System | Tools and methods for using cell division loci to control proliferation of cells |
KR20180032586A (en) * | 2015-07-02 | 2018-03-30 | 메디젠, 인크. | Recombinant virus-like particles using the Bacillus immunodeficiency virus GAG protein |
JP6890831B2 (en) * | 2015-07-08 | 2021-06-18 | アメリカン ジーン テクノロジーズ インターナショナル インコーポレイテッド | HIV preimmunization and immunotherapy |
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2008
- 2008-05-28 WO PCT/US2008/065007 patent/WO2008150814A2/en active Application Filing
- 2008-05-28 CN CN200880101094.4A patent/CN101772580B/en active Active
- 2008-05-28 HU HUE08769761A patent/HUE030872T2/en unknown
- 2008-05-28 RU RU2009148666/10A patent/RU2535365C2/en active
- 2008-05-28 PT PT87697611T patent/PT2164993T/en unknown
- 2008-05-28 EP EP16189709.5A patent/EP3128015A3/en not_active Withdrawn
- 2008-05-28 SG SG10201509679XA patent/SG10201509679XA/en unknown
- 2008-05-28 CN CN201510680523.XA patent/CN105586358B/en active Active
- 2008-05-28 US US12/601,819 patent/US20110217274A1/en not_active Abandoned
- 2008-05-28 EP EP08769761.1A patent/EP2164993B1/en active Active
- 2008-05-28 AU AU2008260187A patent/AU2008260187A1/en not_active Abandoned
- 2008-05-28 SG SG10201903161XA patent/SG10201903161XA/en unknown
- 2008-05-28 JP JP2010510472A patent/JP2010528613A/en active Pending
- 2008-05-28 CA CA2725953A patent/CA2725953A1/en not_active Abandoned
- 2008-05-28 PL PL08769761T patent/PL2164993T3/en unknown
- 2008-05-28 ES ES08769761.1T patent/ES2612538T3/en active Active
- 2008-05-28 BR BRPI0810949A patent/BRPI0810949A2/en not_active Application Discontinuation
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2009
- 2009-11-29 IL IL202401A patent/IL202401A/en active IP Right Grant
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2014
- 2014-10-02 RU RU2014139904A patent/RU2718536C2/en active
- 2014-11-10 JP JP2014227688A patent/JP2015077132A/en active Pending
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2015
- 2015-10-06 IL IL241906A patent/IL241906B/en unknown
Also Published As
Publication number | Publication date |
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EP3128015A2 (en) | 2017-02-08 |
PL2164993T4 (en) | 2017-08-31 |
IL202401A (en) | 2015-10-29 |
EP3128015A3 (en) | 2017-05-03 |
WO2008150814A3 (en) | 2009-02-05 |
JP2015077132A (en) | 2015-04-23 |
IL241906A0 (en) | 2015-11-30 |
EP2164993B1 (en) | 2016-09-21 |
CN105586358B (en) | 2020-08-25 |
EP2164993A2 (en) | 2010-03-24 |
RU2718536C2 (en) | 2020-04-08 |
SG10201509679XA (en) | 2015-12-30 |
BRPI0810949A2 (en) | 2015-10-27 |
RU2014139904A3 (en) | 2018-06-28 |
ES2612538T3 (en) | 2017-05-17 |
CN105586358A (en) | 2016-05-18 |
CA2725953A1 (en) | 2008-12-11 |
AU2008260187A1 (en) | 2008-12-11 |
EP2164993A4 (en) | 2011-04-13 |
JP2010528613A (en) | 2010-08-26 |
WO2008150814A8 (en) | 2009-07-30 |
CN101772580B (en) | 2015-11-25 |
PL2164993T3 (en) | 2017-08-31 |
WO2008150814A2 (en) | 2008-12-11 |
HUE030872T2 (en) | 2017-06-28 |
CN101772580A (en) | 2010-07-07 |
RU2009148666A (en) | 2011-07-10 |
US20110217274A1 (en) | 2011-09-08 |
RU2535365C2 (en) | 2014-12-10 |
PT2164993T (en) | 2017-01-12 |
IL202401A0 (en) | 2011-08-01 |
RU2014139904A (en) | 2016-04-20 |
IL241906B (en) | 2021-07-29 |
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