SG10201902499VA - Therapeutic nanoparticles and related compositions, methods and systems - Google Patents

Therapeutic nanoparticles and related compositions, methods and systems

Info

Publication number
SG10201902499VA
SG10201902499VA SG10201902499VA SG10201902499VA SG10201902499VA SG 10201902499V A SG10201902499V A SG 10201902499VA SG 10201902499V A SG10201902499V A SG 10201902499VA SG 10201902499V A SG10201902499V A SG 10201902499VA SG 10201902499V A SG10201902499V A SG 10201902499VA
Authority
SG
Singapore
Prior art keywords
methods
systems
related compositions
therapeutic nanoparticles
nanoparticles
Prior art date
Application number
SG10201902499VA
Inventor
Gretchen M Unger
Original Assignee
Genesegues Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genesegues Inc filed Critical Genesegues Inc
Publication of SG10201902499VA publication Critical patent/SG10201902499VA/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5169—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle

Abstract

THERAPEUTIC NANOPARTICLES AND RELATED COMPOSITIONS, METHODS AND SYSTEMS Disclosed are targeted sub-50 nanometer nanoparticles suitable for delivering bioactive agents of interest, and related compositions, methods, and systems, which improve the manufacturing, stability, efficacy and other aspects of therapeutic nanoparticles. [No Figure]
SG10201902499VA 2014-09-03 2015-09-03 Therapeutic nanoparticles and related compositions, methods and systems SG10201902499VA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462045519P 2014-09-03 2014-09-03

Publications (1)

Publication Number Publication Date
SG10201902499VA true SG10201902499VA (en) 2019-04-29

Family

ID=54200055

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201701571UA SG11201701571UA (en) 2014-09-03 2015-09-03 Therapeutic nanoparticles and related compositions, methods and systems
SG10201902499VA SG10201902499VA (en) 2014-09-03 2015-09-03 Therapeutic nanoparticles and related compositions, methods and systems

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG11201701571UA SG11201701571UA (en) 2014-09-03 2015-09-03 Therapeutic nanoparticles and related compositions, methods and systems

Country Status (10)

Country Link
US (3) US10987308B2 (en)
EP (1) EP3188716B1 (en)
JP (2) JP6679593B2 (en)
KR (1) KR20170054429A (en)
CN (2) CN111700877A (en)
AU (1) AU2015311857A1 (en)
CA (1) CA2959660A1 (en)
IL (1) IL250844A0 (en)
SG (2) SG11201701571UA (en)
WO (1) WO2016036960A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190151470A1 (en) 2018-01-21 2019-05-23 RoverMed BioSciences, LLC Nanoparticles comprising protein-polynucleotide complexes and for delivering protein based complexes
CN108478528B (en) * 2018-04-20 2020-11-10 西北大学 Targeting polymer drug-loaded micelle and preparation method thereof
EP4186916A1 (en) 2020-07-22 2023-05-31 3H Bio. Co., Ltd. Peptide for immunotherapeutic agent

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