SG10201710488TA - Delivery, Engineering and Optimization of Systems, Methods and Compositions for Targeting and Modeling Diseases and Disorders of Post Mitotic Cells - Google Patents

Delivery, Engineering and Optimization of Systems, Methods and Compositions for Targeting and Modeling Diseases and Disorders of Post Mitotic Cells

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Publication number
SG10201710488TA
SG10201710488TA SG10201710488TA SG10201710488TA SG10201710488TA SG 10201710488T A SG10201710488T A SG 10201710488TA SG 10201710488T A SG10201710488T A SG 10201710488TA SG 10201710488T A SG10201710488T A SG 10201710488TA SG 10201710488T A SG10201710488T A SG 10201710488TA
Authority
SG
Singapore
Prior art keywords
targeting
disorders
optimization
engineering
delivery
Prior art date
Application number
SG10201710488TA
Inventor
Zhang Feng
HEIDENREICH Matthias
Swiech Lukasz
Original Assignee
Broad Inst Inc
Massachusetts Inst Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52105123&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG10201710488T(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from PCT/US2013/074667 external-priority patent/WO2014093622A2/en
Application filed by Broad Inst Inc, Massachusetts Inst Technology filed Critical Broad Inst Inc
Publication of SG10201710488TA publication Critical patent/SG10201710488TA/en

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    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New breeds of animals
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
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    • A61K48/0058—Nucleic acids adapted for tissue specific expression, e.g. having tissue specific promoters as part of a contruct
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    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases RNAses, DNAses
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A01K2217/052—Animals comprising random inserted nucleic acids (transgenic) inducing gain of function
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14151—Methods of production or purification of viral material
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    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
SG10201710488TA 2013-06-17 2014-06-11 Delivery, Engineering and Optimization of Systems, Methods and Compositions for Targeting and Modeling Diseases and Disorders of Post Mitotic Cells SG10201710488TA (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201361836123P 2013-06-17 2013-06-17
US201361847537P 2013-07-17 2013-07-17
US201361862355P 2013-08-05 2013-08-05
US201361871301P 2013-08-28 2013-08-28
US201361915203P 2013-12-12 2013-12-12
PCT/US2013/074667 WO2014093622A2 (en) 2012-12-12 2013-12-12 Delivery, engineering and optimization of systems, methods and compositions for sequence manipulation and therapeutic applications
US201461979573P 2014-04-15 2014-04-15

Publications (1)

Publication Number Publication Date
SG10201710488TA true SG10201710488TA (en) 2018-01-30

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SG10201710488TA SG10201710488TA (en) 2013-06-17 2014-06-11 Delivery, Engineering and Optimization of Systems, Methods and Compositions for Targeting and Modeling Diseases and Disorders of Post Mitotic Cells
SG11201510327TA SG11201510327TA (en) 2013-06-17 2014-06-11 Delivery, engineering and optimization of systems, methods and compositions for targeting and modeling diseases and disorders of post mitotic cells

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SG11201510327TA SG11201510327TA (en) 2013-06-17 2014-06-11 Delivery, engineering and optimization of systems, methods and compositions for targeting and modeling diseases and disorders of post mitotic cells

Country Status (15)

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US (1) US20160153004A1 (en)
EP (2) EP3620524A1 (en)
JP (2) JP6738729B2 (en)
KR (1) KR20160019553A (en)
CN (1) CN105683379A (en)
AU (1) AU2014281030B2 (en)
BR (1) BR112015031611A2 (en)
CA (1) CA2915845A1 (en)
DK (1) DK3011032T3 (en)
ES (1) ES2767318T3 (en)
IL (1) IL243197B (en)
MX (1) MX2015017311A (en)
RU (1) RU2725502C2 (en)
SG (2) SG10201710488TA (en)
WO (1) WO2014204728A1 (en)

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US11661590B2 (en) 2016-08-09 2023-05-30 President And Fellows Of Harvard College Programmable CAS9-recombinase fusion proteins and uses thereof
US11732274B2 (en) 2017-07-28 2023-08-22 President And Fellows Of Harvard College Methods and compositions for evolving base editors using phage-assisted continuous evolution (PACE)
US11820969B2 (en) 2016-12-23 2023-11-21 President And Fellows Of Harvard College Editing of CCR2 receptor gene to protect against HIV infection
US11898179B2 (en) 2017-03-09 2024-02-13 President And Fellows Of Harvard College Suppression of pain by gene editing
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US11920181B2 (en) 2013-08-09 2024-03-05 President And Fellows Of Harvard College Nuclease profiling system
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