SG10201705895TA - Microdevices for separation of non-spherical particles and applications thereof - Google Patents

Microdevices for separation of non-spherical particles and applications thereof

Info

Publication number
SG10201705895TA
SG10201705895TA SG10201705895TA SG10201705895TA SG10201705895TA SG 10201705895T A SG10201705895T A SG 10201705895TA SG 10201705895T A SG10201705895T A SG 10201705895TA SG 10201705895T A SG10201705895T A SG 10201705895TA SG 10201705895T A SG10201705895T A SG 10201705895TA
Authority
SG
Singapore
Prior art keywords
microdevices
separation
applications
spherical particles
spherical
Prior art date
Application number
SG10201705895TA
Inventor
Yong Zhang
Shashi Ranjan
Zeming Kerwin Kwek
Original Assignee
Nat Univ Singapore
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nat Univ Singapore filed Critical Nat Univ Singapore
Publication of SG10201705895TA publication Critical patent/SG10201705895TA/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D21/00—Separation of suspended solid particles from liquids by sedimentation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/08—Regulating or influencing the flow resistance
    • B01L2400/084—Passive control of flow resistance
    • B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1484—Electro-optical investigation, e.g. flow cytometers microstructural devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
    • G01N2001/4083—Concentrating samples by other techniques involving separation of suspended solids sedimentation
SG10201705895TA 2013-01-24 2014-01-23 Microdevices for separation of non-spherical particles and applications thereof SG10201705895TA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361849331P 2013-01-24 2013-01-24

Publications (1)

Publication Number Publication Date
SG10201705895TA true SG10201705895TA (en) 2017-08-30

Family

ID=51227867

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201705895TA SG10201705895TA (en) 2013-01-24 2014-01-23 Microdevices for separation of non-spherical particles and applications thereof
SG11201505411RA SG11201505411RA (en) 2013-01-24 2014-01-23 Microdevices for separation of non-spherical particles and applications thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201505411RA SG11201505411RA (en) 2013-01-24 2014-01-23 Microdevices for separation of non-spherical particles and applications thereof

Country Status (3)

Country Link
US (1) US20150362413A1 (en)
SG (2) SG10201705895TA (en)
WO (1) WO2014116183A1 (en)

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US10040018B2 (en) 2013-01-09 2018-08-07 Imagine Tf, Llc Fluid filters and methods of use
EP2971279B1 (en) 2013-03-15 2019-11-13 The Trustees of Princeton University Methods and devices for high throughput purification
CN105264127B (en) 2013-03-15 2019-04-09 Gpb科学有限责任公司 The on piece microfluidic process of particle
US20150064153A1 (en) 2013-03-15 2015-03-05 The Trustees Of Princeton University High efficiency microfluidic purification of stem cells to improve transplants
US9861920B1 (en) 2015-05-01 2018-01-09 Imagine Tf, Llc Three dimensional nanometer filters and methods of use
US10730047B2 (en) 2014-06-24 2020-08-04 Imagine Tf, Llc Micro-channel fluid filters and methods of use
US10124275B2 (en) 2014-09-05 2018-11-13 Imagine Tf, Llc Microstructure separation filters
WO2016133929A1 (en) 2015-02-18 2016-08-25 Imagine Tf, Llc Three dimensional filter devices and apparatuses
US10668467B2 (en) 2015-06-10 2020-06-02 Texas Tech University System Microfluidic device for studying nematodes
US10118842B2 (en) 2015-07-09 2018-11-06 Imagine Tf, Llc Deionizing fluid filter devices and methods of use
US10479046B2 (en) 2015-08-19 2019-11-19 Imagine Tf, Llc Absorbent microstructure arrays and methods of use
US10976232B2 (en) 2015-08-24 2021-04-13 Gpb Scientific, Inc. Methods and devices for multi-step cell purification and concentration
WO2017167361A1 (en) * 2016-03-30 2017-10-05 Siemens Healthcare Gmbh Aligning a non-spherical biological entity in a sample flow using ambient viscoelastic fluid flows
US11207683B2 (en) * 2016-08-02 2021-12-28 Imec Vzw Method and arrangement for focusing objects in a flow
US10010883B2 (en) * 2016-09-20 2018-07-03 International Business Machines Corporation Deterministic lateral displacement arrays
JP6923181B2 (en) * 2016-11-30 2021-08-18 国立大学法人東京工業大学 Fine particle separation device and fine particle separation method
AU2018323875A1 (en) 2017-09-01 2020-04-23 Gpb Scientific, Inc. Methods for preparing therapeutically active cells using microfluidics
US11229912B2 (en) 2018-03-27 2022-01-25 Hewlett-Packard Development Company, L.P. Particle separation
CN108753572B (en) * 2018-06-06 2021-03-02 深圳市瑞格生物科技有限公司 Lateral offset micro-column array chip and application thereof
US11890616B2 (en) 2019-03-26 2024-02-06 The Curators Of The University Of Missouri Microfluidic device for capture of micrometer scale objects and methods of using the device
TW202045243A (en) * 2019-06-05 2020-12-16 薩摩亞商曦醫生技股份有限公司 Microfluidic device which can process great amount of liquid samples per a unit time and has good filtering effect
US11266989B2 (en) * 2019-08-07 2022-03-08 International Business Machines Corporation Immunodetection and separation on nanoDLD
US20220250070A1 (en) * 2019-09-14 2022-08-11 Hewlett-Packard Development Company, L.P. Vortex particle separation
CN112557261B (en) * 2020-12-07 2022-12-09 昆明理工大学 Erythrocyte separation detection device and separation detection method based on C-shaped microcolumn

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JP2006501449A (en) * 2002-09-27 2006-01-12 ザ ジェネラル ホスピタル コーポレーション Microfluidic device for cell separation and use thereof
EP2294832B1 (en) * 2008-06-30 2012-01-11 Freescale Semiconductor, Inc. Multi-frequency tone detector
EP2344883A4 (en) * 2008-09-26 2012-03-21 Gen Hospital Corp Capturing particles
WO2010080978A2 (en) * 2009-01-08 2010-07-15 The General Hospital Corporation Pre-depletion of leukocytes in whole blood samples prior to the capture of whole blood sample components

Also Published As

Publication number Publication date
WO2014116183A1 (en) 2014-07-31
SG11201505411RA (en) 2015-08-28
US20150362413A1 (en) 2015-12-17

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