SG10201609831UA - BIOTECHNOLOGICAL PRODUCTION OF ω-FUNCTIONALISED CARBOXYLIC ACIDS AND ESTERS THEREOF - Google Patents

BIOTECHNOLOGICAL PRODUCTION OF ω-FUNCTIONALISED CARBOXYLIC ACIDS AND ESTERS THEREOF

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Publication number
SG10201609831UA
SG10201609831UA SG10201609831UA SG10201609831UA SG10201609831UA SG 10201609831U A SG10201609831U A SG 10201609831UA SG 10201609831U A SG10201609831U A SG 10201609831UA SG 10201609831U A SG10201609831U A SG 10201609831UA SG 10201609831U A SG10201609831U A SG 10201609831UA
Authority
SG
Singapore
Prior art keywords
esters
carboxylic acids
biotechnological production
functionalised carboxylic
functionalised
Prior art date
Application number
SG10201609831UA
Inventor
Steffen Schaffer Dr
Thomas Haas Dr
Wilhelm Brügging Dr
Meier Ralf
Original Assignee
Evonik Degussa Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Degussa Gmbh filed Critical Evonik Degussa Gmbh
Publication of SG10201609831UA publication Critical patent/SG10201609831UA/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/001Amines; Imines
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/62Carboxylic acid esters
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0077Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with a reduced iron-sulfur protein as one donor (1.14.15)
    • CCHEMISTRY; METALLURGY
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/1029Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1096Transferases (2.) transferring nitrogenous groups (2.6)
    • CCHEMISTRY; METALLURGY
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    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/24Preparation of oxygen-containing organic compounds containing a carbonyl group
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • C12P7/649Biodiesel, i.e. fatty acid alkyl esters
    • CCHEMISTRY; METALLURGY
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    • C12YENZYMES
    • C12Y101/00Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01001Alcohol dehydrogenase (1.1.1.1)
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    • C12Y101/00Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01002Alcohol dehydrogenase (NADP+) (1.1.1.2), i.e. aldehyde reductase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y101/00Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/03Oxidoreductases acting on the CH-OH group of donors (1.1) with a oxygen as acceptor (1.1.3)
    • C12Y101/0302Long-chain-alcohol oxidase (1.1.3.20)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y114/00Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/15Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen (1.14.15)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y114/00Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/15Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen (1.14.15)
    • C12Y114/15003Alkane 1-monooxygenase (1.14.15.3)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y203/00Acyltransferases (2.3)
    • C12Y203/01Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01075Long-chain-alcohol O-fatty-acyltransferase (2.3.1.75)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y203/00Acyltransferases (2.3)
    • C12Y203/01Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01084Alcohol O-acetyltransferase (2.3.1.84)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y206/00Transferases transferring nitrogenous groups (2.6)
    • C12Y206/01Transaminases (2.6.1)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00Technologies for the production of fuel of non-fossil origin
    • Y02E50/10Biofuels, e.g. bio-diesel
SG10201609831UA 2015-11-25 2016-11-23 BIOTECHNOLOGICAL PRODUCTION OF ω-FUNCTIONALISED CARBOXYLIC ACIDS AND ESTERS THEREOF SG10201609831UA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP15196180 2015-11-25

Publications (1)

Publication Number Publication Date
SG10201609831UA true SG10201609831UA (en) 2017-06-29

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ID=54770815

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SG10201609831UA SG10201609831UA (en) 2015-11-25 2016-11-23 BIOTECHNOLOGICAL PRODUCTION OF ω-FUNCTIONALISED CARBOXYLIC ACIDS AND ESTERS THEREOF
SG10202002995VA SG10202002995VA (en) 2015-11-25 2016-11-23 BIOTECHNOLOGICAL PRODUCTION OF ω-FUNCTIONALISED CARBOXYLIC ACIDS AND ESTERS THEREOF

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Country Status (15)

Country Link
US (1) US10913960B2 (en)
EP (1) EP3173478A1 (en)
JP (2) JP6925118B2 (en)
KR (1) KR20170061088A (en)
CN (1) CN107034246A (en)
AR (1) AR106816A1 (en)
AU (1) AU2016262715B2 (en)
BR (1) BR102016027703A2 (en)
CA (1) CA2949410A1 (en)
MX (1) MX2016015380A (en)
MY (1) MY191006A (en)
RU (1) RU2751363C2 (en)
SG (2) SG10201609831UA (en)
TW (1) TWI790195B (en)
UA (1) UA127099C2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017102952A1 (en) 2015-12-17 2017-06-22 Evonik Degussa Gmbh A genetically modified acetogenic cell
JP2019523271A (en) 2016-07-27 2019-08-22 エボニック デグサ ゲーエムベーハーEvonik Degussa GmbH N-acetylhomoserine
CN109486784B (en) * 2018-11-30 2020-06-09 江南大学 Omega-transaminase mutant capable of catalyzing sitafloxacin five-membered ring key intermediate

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999004014A2 (en) * 1997-07-21 1999-01-28 E.I. Du Pont De Nemours And Company Transformed yeast strains and their use for the production of monoterminal and diterminal aliphatic carboxylates
RU2376868C2 (en) * 2003-01-17 2009-12-27 Даниско А/С Method
EP2024501B1 (en) 2006-05-11 2016-11-16 Evonik Degussa GmbH Improved production of sphingoid bases using genetically engineered microbial strains
EP2594633A1 (en) * 2007-03-28 2013-05-22 LS9, Inc. Enhanced production of fatty acid derivatives
DE102007052463A1 (en) 2007-11-02 2009-05-07 Evonik Degussa Gmbh Fermentative recovery of acetone from renewable resources using a new metabolic pathway
DE102007060705A1 (en) 2007-12-17 2009-06-18 Evonik Degussa Gmbh ω-aminocarboxylic acids or their lactams, producing, recombinant cells
DE102008040193A1 (en) 2008-07-04 2010-01-07 Evonik Röhm Gmbh Process for the preparation of free carboxylic acids
DE102009000661A1 (en) 2009-02-06 2010-08-12 Evonik Degussa Gmbh Preparing (1S,5S)-2,6-dioxabicyclo-(3.3.0)-octan-4,8-dione, comprises oxidizing dianhydrohexitols or their corresponding hydroxy ketones with oxygen-containing gas in the presence of catalyst composition containing e.g. a nitroxyl radical
DE102009009580A1 (en) 2009-02-19 2010-08-26 Evonik Degussa Gmbh Process for the preparation of free acids from their salts
US8158391B2 (en) 2009-05-06 2012-04-17 Dna Twopointo, Inc. Production of an α-carboxyl-ω-hydroxy fatty acid using a genetically modified Candida strain
ES2707747T3 (en) 2009-09-25 2019-04-04 Reg Life Sciences Llc Production of fatty acid derivatives
DE102009046623A1 (en) 2009-11-11 2011-05-12 Evonik Röhm Gmbh Use of a protein homologous to a MeaB protein to increase the enzymatic activity of a 3-hydroxycarboxylic acid CoA mutase
DE102009046626A1 (en) 2009-11-11 2011-05-12 Evonik Degussa Gmbh Candida tropicalis cells and their use
DE102010015807A1 (en) 2010-04-20 2011-10-20 Evonik Degussa Gmbh Biocatalytic oxidation process with alkL gene product
DE102011110946A1 (en) 2011-08-15 2016-01-21 Evonik Degussa Gmbh Biotechnological synthesis of omega-functionalized carboxylic acids and carboxylic acid esters from simple carbon sources
PT2753701T (en) * 2011-09-27 2018-08-10 Exxonmobil Res & Eng Co Acyl-acp wax ester synthases
EP2944697A1 (en) * 2014-05-13 2015-11-18 Evonik Degussa GmbH Method of producing nylon

Also Published As

Publication number Publication date
MY191006A (en) 2022-05-27
JP2021129603A (en) 2021-09-09
MX2016015380A (en) 2017-05-24
SG10202002995VA (en) 2020-05-28
JP7186261B2 (en) 2022-12-08
JP2017140015A (en) 2017-08-17
CN107034246A (en) 2017-08-11
RU2016146334A3 (en) 2020-04-30
EP3173478A1 (en) 2017-05-31
TW201739914A (en) 2017-11-16
US20170145448A1 (en) 2017-05-25
AR106816A1 (en) 2018-02-21
JP6925118B2 (en) 2021-08-25
TWI790195B (en) 2023-01-21
RU2016146334A (en) 2018-05-28
BR102016027703A2 (en) 2017-05-30
US10913960B2 (en) 2021-02-09
CA2949410A1 (en) 2017-05-25
UA127099C2 (en) 2023-04-19
AU2016262715A1 (en) 2017-06-08
AU2016262715B2 (en) 2022-12-22
RU2751363C2 (en) 2021-07-13
KR20170061088A (en) 2017-06-02

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