SG10201606204TA - Treatment Of Multiple Sclerosis With Combination Of Laquinimod And Interferon-Beta - Google Patents

Treatment Of Multiple Sclerosis With Combination Of Laquinimod And Interferon-Beta

Info

Publication number
SG10201606204TA
SG10201606204TA SG10201606204TA SG10201606204TA SG10201606204TA SG 10201606204T A SG10201606204T A SG 10201606204TA SG 10201606204T A SG10201606204T A SG 10201606204TA SG 10201606204T A SG10201606204T A SG 10201606204TA SG 10201606204T A SG10201606204T A SG 10201606204TA
Authority
SG
Singapore
Prior art keywords
laquinimod
interferon
beta
treatment
combination
Prior art date
Application number
SG10201606204TA
Other languages
English (en)
Inventor
Yossi Gilgun
Nora Tarcic
Pharmaceuticals Usa Inc Teva
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma filed Critical Teva Pharma
Publication of SG10201606204TA publication Critical patent/SG10201606204TA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/215—IFN-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Packages (AREA)
SG10201606204TA 2011-07-28 2012-07-27 Treatment Of Multiple Sclerosis With Combination Of Laquinimod And Interferon-Beta SG10201606204TA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161512817P 2011-07-28 2011-07-28

Publications (1)

Publication Number Publication Date
SG10201606204TA true SG10201606204TA (en) 2016-09-29

Family

ID=47597382

Family Applications (1)

Application Number Title Priority Date Filing Date
SG10201606204TA SG10201606204TA (en) 2011-07-28 2012-07-27 Treatment Of Multiple Sclerosis With Combination Of Laquinimod And Interferon-Beta

Country Status (16)

Country Link
US (3) US20130028866A1 (fr)
EP (1) EP2736336A4 (fr)
JP (2) JP2014521659A (fr)
KR (1) KR20140054129A (fr)
CN (1) CN103781355A (fr)
AU (2) AU2012286701A1 (fr)
BR (1) BR112014002092A2 (fr)
CA (1) CA2843432A1 (fr)
EA (1) EA201490378A1 (fr)
HK (1) HK1198278A1 (fr)
MX (1) MX2014001048A (fr)
SG (1) SG10201606204TA (fr)
TW (1) TW201726137A (fr)
UY (1) UY34359A (fr)
WO (1) WO2013016686A1 (fr)
ZA (1) ZA201401217B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2600920T3 (es) 2007-12-20 2017-02-13 Teva Pharmaceutical Industries, Ltd. Preparaciones estables de laquinimod
EP2542079B1 (fr) 2010-03-03 2014-05-21 Teva Pharmaceutical Industries Ltd. Traitement de la polyarthrite rhumatoïde au moyen d'une combinaison de laquinimod et de méthotrexate
KR20130006640A (ko) * 2010-03-03 2013-01-17 테바 파마슈티컬 인더스트리즈 리미티드 라퀴니모드를 이용한 루푸스 신장염의 치료
CN106344576A (zh) 2011-10-12 2017-01-25 泰华制药工业有限公司 以拉喹莫德和芬戈莫德的组合治疗多发性硬化症
EP2811832A4 (fr) 2012-02-03 2015-09-23 Teva Pharma Utilisation de laquinimod pour le traitement de patients souffrant de la maladie de crohn pour lesquels la thérapie anti-tnf de première intention a échoué
EP2744498A4 (fr) 2012-02-16 2014-12-03 Teva Pharma N-éthyl-n-phényl -1,2-dihydro -4,5-di-hydroxy -1-méthyl -2-oxo -3-quinoléine carboxamide, sa préparation et son utilisation
FR2988058B1 (fr) 2012-03-15 2014-10-03 A Fermetures As Dispositif de calage a quai de vehicule de transport de marchandises
TW201350467A (zh) 2012-05-08 2013-12-16 Teva Pharma Ｎ－乙基－４－羥基－１－甲基－５－（甲基（２，３，４，５，６－五羥基己基）胺基）－２－側氧－ｎ－苯基－１，２－二氫喹啉－３－甲醯胺
TW201400117A (zh) 2012-06-05 2014-01-01 Teva Pharma 使用拉喹莫德治療眼發炎疾病
AR091706A1 (es) * 2012-07-11 2015-02-25 Teva Pharma Formulaciones de laquinimod sin agentes alcalinizantes
TW201410244A (zh) 2012-08-13 2014-03-16 Teva Pharma 用於治療ｇａｂａ媒介之疾病之拉喹莫德（ｌａｑｕｉｎｉｍｏｄ）
EA201590788A1 (ru) 2012-11-07 2015-12-30 Тева Фармасьютикал Индастриз Лтд. Аминные соли лахинимода
CA2900503A1 (fr) * 2013-02-15 2014-08-21 Teva Pharmaceutical Industries Ltd. Traitement de la sclerose en plaques a l'aide de laquinimod
EA201591699A1 (ru) 2013-03-14 2016-02-29 Тева Фармасьютикал Индастриз Лтд. Кристаллы лаквинимода натрия и улучшенный способ их производства
WO2015017690A1 (fr) * 2013-08-01 2015-02-05 Teva Pharmaceutical Industries Ltd. Traitement de la sclérose en plaques par induction à l'alemtuzumab suivie par une thérapie par laquinimod
AU2015253330A1 (en) * 2014-04-29 2016-12-01 Teva Pharmaceutical Industries Ltd. Laquinimod for the treatment of relapsing-remitting multiple sclerosis (RRMS) patients with a high disability status
EP3303559A1 (fr) * 2015-06-01 2018-04-11 Biogen MA Inc. Supplémentation en manganèse pour la régulation de la glycosylation dans un procédé de culture cellulaire de mammifère
US20190108912A1 (en) * 2017-10-05 2019-04-11 Iquity, Inc. Methods for predicting or detecting disease

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6077851A (en) * 1998-04-27 2000-06-20 Active Biotech Ab Quinoline derivatives
KR20080050591A (ko) * 2005-09-01 2008-06-09 아레스 트레이딩 에스.에이. 시신경염 치료
ATE532515T1 (de) * 2006-06-12 2011-11-15 Teva Pharma Stabile laquinimod-zubereitungen
US20110195049A1 (en) * 2008-10-13 2011-08-11 Biovista, Inc. Compositions and methods for treating multiple sclerosis
BR112012000568A2 (pt) * 2009-06-19 2015-10-06 Teva Pharma tratamento da esclerose múltipla com laquinimod
EP2455080A1 (fr) * 2010-11-23 2012-05-23 Almirall, S.A. Agonistes de récepteur S1P1 à utiliser dans le traitement de la sclérose en plaques
AU2015253330A1 (en) * 2014-04-29 2016-12-01 Teva Pharmaceutical Industries Ltd. Laquinimod for the treatment of relapsing-remitting multiple sclerosis (RRMS) patients with a high disability status

Also Published As

Publication number Publication date
NZ621215A (en) 2015-11-27
US20160166648A1 (en) 2016-06-16
HK1198278A1 (en) 2015-03-27
KR20140054129A (ko) 2014-05-08
AU2012286701A1 (en) 2014-03-06
US20130028866A1 (en) 2013-01-31
US20150056281A1 (en) 2015-02-26
WO2013016686A1 (fr) 2013-01-31
AU2016204909A1 (en) 2016-08-04
EP2736336A4 (fr) 2015-03-04
TW201726137A (zh) 2017-08-01
CN103781355A (zh) 2014-05-07
EA201490378A1 (ru) 2014-07-30
JP2017061482A (ja) 2017-03-30
CA2843432A1 (fr) 2013-01-31
EP2736336A1 (fr) 2014-06-04
JP2014521659A (ja) 2014-08-28
ZA201401217B (en) 2015-08-26
UY34359A (es) 2014-02-28
MX2014001048A (es) 2014-07-09
BR112014002092A2 (pt) 2017-02-21

Similar Documents

Publication Publication Date Title
ZA201401217B (en) Treatment of multiple sclerosis with combination of laquinimod and interferon-beta
IL251397A0 (en) Treatment of multiple sclerosis by administering a combination of laquinimod and glatiramer acetate
IL252699A0 (en) Use of lequinimod to treat multiple sclerosis
HK1199820A1 (en) Treatment of multiple sclerosis with combination of laquinimod and fingolimod
HK1205941A1 (en) Treatment of multiple sclerosis with combination of laquinimod and dimethyl fumarate
IL252547A0 (en) Treatment of multiple sclerosis using laquinimod
HK1209672A1 (en) Treatment of multiple sclerosis with combination of laquinimod and fampridine
HK1218254A1 (zh) 用拉喹莫德治療多發性硬化症
ZA201408062B (en) Compositions and methods for the treatment of multiple sclerosis
EP2670406A4 (fr) Thérapie combinée par un interféron et des andrographolides destinés à la sclérose en plaques
HK1223855A1 (zh) 拉喹莫德和氟吡汀組合物用於治療多發性硬化症
HK1227691A1 (zh) 利用拉喹莫德和特立氟胺的組合來治療多發性硬化症