SG10201400171PA - Cholestanol derivative for combined use - Google Patents

Cholestanol derivative for combined use

Info

Publication number
SG10201400171PA
SG10201400171PA SG10201400171PA SG10201400171PA SG10201400171PA SG 10201400171P A SG10201400171P A SG 10201400171PA SG 10201400171P A SG10201400171P A SG 10201400171PA SG 10201400171P A SG10201400171P A SG 10201400171PA SG 10201400171P A SG10201400171P A SG 10201400171PA
Authority
SG
Singapore
Prior art keywords
combined use
cholestanol derivative
cholestanol
derivative
combined
Prior art date
Application number
SG10201400171PA
Inventor
Shin Yazawa
Toyo Nishimura
Takayuki Asao
Original Assignee
Otsuka Pharma Co Ltd
Univ Gunma Nat Univ Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd, Univ Gunma Nat Univ Corp filed Critical Otsuka Pharma Co Ltd
Publication of SG10201400171PA publication Critical patent/SG10201400171PA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/282Platinum compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/664Amides of phosphorus acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A61K31/7072Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/724Cyclodextrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J17/00Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J17/005Glycosides
SG10201400171PA 2008-03-05 2009-09-03 Cholestanol derivative for combined use SG10201400171PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2008055284 2008-03-05
PCT/JP2009/000985 WO2009110235A1 (en) 2008-03-05 2009-03-04 Combined use of cholestanol derivative

Publications (1)

Publication Number Publication Date
SG10201400171PA true SG10201400171PA (en) 2014-06-27

Family

ID=41055800

Family Applications (2)

Application Number Title Priority Date Filing Date
SG2013013800A SG188805A1 (en) 2008-03-05 2009-03-04 Combined use of cholestanol derivative
SG10201400171PA SG10201400171PA (en) 2008-03-05 2009-09-03 Cholestanol derivative for combined use

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG2013013800A SG188805A1 (en) 2008-03-05 2009-03-04 Combined use of cholestanol derivative

Country Status (27)

Country Link
US (6) US8088744B2 (en)
EP (1) EP2251014B8 (en)
JP (1) JP5336466B2 (en)
KR (1) KR20100120674A (en)
CN (2) CN101678037B (en)
AR (1) AR070857A1 (en)
AU (1) AU2009220699C1 (en)
BR (2) BRPI0908756A2 (en)
CA (1) CA2717135A1 (en)
CO (2) CO6311080A2 (en)
CY (1) CY1115217T1 (en)
DK (1) DK2251014T3 (en)
ES (1) ES2437640T3 (en)
HK (1) HK1145455A1 (en)
HR (2) HRP20140154T1 (en)
IL (1) IL207874A (en)
MX (1) MX2010009794A (en)
NZ (2) NZ587729A (en)
PL (1) PL2251014T3 (en)
PT (1) PT2251014E (en)
RU (1) RU2492865C2 (en)
SG (2) SG188805A1 (en)
SI (1) SI2251014T1 (en)
TW (1) TWI492759B (en)
UA (2) UA101831C2 (en)
WO (1) WO2009110235A1 (en)
ZA (1) ZA201006228B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ548195A (en) * 2004-01-14 2011-01-28 Gilead Sciences Inc Lipid-based dispersions useful for drug delivery
PT2404608E (en) * 2009-03-04 2015-07-21 Otsuka Pharma Co Ltd Cholestanol derivative for combined use
JP5480241B2 (en) * 2009-03-04 2014-04-23 大塚製薬株式会社 Combined use of cholestanol derivatives
WO2013179310A1 (en) * 2012-05-31 2013-12-05 Mylan Laboratories Limited Stable aqueous compositions of pemetrexed
WO2024018412A1 (en) * 2022-07-20 2024-01-25 University Of The Witwatersrand, Johannesburg 2-hydroxypropyl-beta-cyclodextrin as a cancer therapy neoadjuvant or adjuvant

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5782310A (en) 1980-11-11 1982-05-22 Tanabe Seiyaku Co Ltd Production of liposome preparation
JPS6012127A (en) 1983-06-30 1985-01-22 Dai Ichi Seiyaku Co Ltd Preparing method of liposome
JPS6058915A (en) 1983-09-12 1985-04-05 Fujisawa Pharmaceut Co Ltd Lipid microcapsule preparation containing medicament
JPH0610131B2 (en) 1987-10-30 1994-02-09 テルモ株式会社 Liposomal manufacturing method
JPH01167218A (en) 1987-12-22 1989-06-30 Sumitomo Electric Ind Ltd Production of superconducting thin film
JPH082780B2 (en) 1990-05-28 1996-01-17 テルモ株式会社 Liposomal manufacturing method
JP3831958B2 (en) 1995-09-20 2006-10-11 日本油脂株式会社 Lipid mixed lipid and liposome dispersion
JP4105258B2 (en) * 1997-08-19 2008-06-25 大塚製薬株式会社 Cholestanol compound and medicine containing the same
JP4351314B2 (en) 1998-12-24 2009-10-28 大塚製薬株式会社 Cholestanol compound and medicine containing the same
EE200200565A (en) * 2000-03-31 2004-06-15 Angiogene Pharmaceuticals Ltd. Combination therapy with vascular adverse effects
AU2004257509B2 (en) 2003-07-17 2008-12-18 Otsuka Pharmaceutical Co., Ltd. Glycoside-containing liposome
MXPA06006291A (en) * 2003-12-08 2006-08-23 Univ Arizona Synergistic anti-cancer compositions.
EP1753512B1 (en) * 2004-05-28 2008-07-09 Nycomed GmbH Tetrahydropyridothiophenes
TWI373473B (en) * 2005-09-02 2012-10-01 Otsuka Pharma Co Ltd Anticancer agent

Also Published As

Publication number Publication date
BRPI0908756A2 (en) 2015-07-21
US20100062053A1 (en) 2010-03-11
JPWO2009110235A1 (en) 2011-07-14
NZ587729A (en) 2012-03-30
US20150374730A1 (en) 2015-12-31
PT2251014E (en) 2014-02-14
US20120015025A1 (en) 2012-01-19
CN101678037A (en) 2010-03-24
SI2251014T1 (en) 2014-02-28
US20140178464A1 (en) 2014-06-26
NZ595615A (en) 2013-06-28
HK1145455A1 (en) 2011-04-21
CO6311080A2 (en) 2011-08-22
HRP20150418T1 (en) 2015-05-08
US8088744B2 (en) 2012-01-03
CN101678037B (en) 2012-07-25
EP2251014B1 (en) 2013-11-20
CN101969961B (en) 2013-01-16
CY1115217T1 (en) 2017-01-04
US20130101679A1 (en) 2013-04-25
UA101884C2 (en) 2013-05-13
CN101969961A (en) 2011-02-09
SG188805A1 (en) 2013-04-30
KR20100120674A (en) 2010-11-16
HRP20140154T1 (en) 2014-03-14
RU2492865C2 (en) 2013-09-20
TW200940097A (en) 2009-10-01
JP5336466B2 (en) 2013-11-06
MX2010009794A (en) 2010-12-21
CO6361931A2 (en) 2012-01-20
IL207874A (en) 2014-05-28
BRPI0924525A2 (en) 2016-03-01
US20120009251A1 (en) 2012-01-12
AR070857A1 (en) 2010-05-12
TWI492759B (en) 2015-07-21
EP2251014A4 (en) 2012-05-23
EP2251014A1 (en) 2010-11-17
DK2251014T3 (en) 2013-12-02
AU2009220699A1 (en) 2009-09-11
IL207874A0 (en) 2010-12-30
PL2251014T3 (en) 2014-04-30
ES2437640T3 (en) 2014-01-13
ZA201006228B (en) 2011-11-30
UA101831C2 (en) 2013-05-13
CA2717135A1 (en) 2009-09-11
AU2009220699B2 (en) 2013-06-20
EP2251014B8 (en) 2014-01-08
WO2009110235A1 (en) 2009-09-11
RU2010140611A (en) 2012-04-10
AU2009220699C1 (en) 2014-01-16

Similar Documents

Publication Publication Date Title
GB0810902D0 (en) New compounds
EP2376493A4 (en) Dihydropyrimidopyrimidine derivative
EP2380877A4 (en) Pyridine-3-carboxyamide derivative
HK1158189A1 (en) Morpholinopurine derivative
EP2331543A4 (en) 3-deazaneplanocin derivatives
EP2291078A4 (en) Oxazolobenzimidazole derivatives
EP2269993A4 (en) 2-aminoquinazoline derivative
EP2279532A4 (en) Oxazolobenzimidazole derivatives
ZA201005769B (en) Bicycloamine derivative
IL208623A0 (en) Cyclopentylacrylamide derivative
IL211290A0 (en) New 2-amidothiadiazole derivatives
IL210344A0 (en) New compounds
EP2292613A4 (en) Dihydroindolinone derivatives
SG10201400171PA (en) Cholestanol derivative for combined use
ZA201006992B (en) Hydroxyquinoxalinecarboxamide derivative
EP2248811A4 (en) 2-oxochromene derivative
GB0814728D0 (en) New combination
IL212683A0 (en) Biphenylacetamide derivative
GB0823140D0 (en) New combination
GB0811100D0 (en) New combination
HU0800478D0 (en) New compounds
GB0814729D0 (en) New combination
HK1160019A1 (en) Cholestanol derivative for combined use
EP2328892A4 (en) Oxotetrahydrofuran-2-yl-benzimidazole derivative
GB0823141D0 (en) New combination