SE9502902L - Method for quantitative and qualitative determination of chemical substances whose functional principle is based on molecular recognition and measurement of the magnetic permeability - Google Patents

Method for quantitative and qualitative determination of chemical substances whose functional principle is based on molecular recognition and measurement of the magnetic permeability

Info

Publication number
SE9502902L
SE9502902L SE9502902A SE9502902A SE9502902L SE 9502902 L SE9502902 L SE 9502902L SE 9502902 A SE9502902 A SE 9502902A SE 9502902 A SE9502902 A SE 9502902A SE 9502902 L SE9502902 L SE 9502902L
Authority
SE
Sweden
Prior art keywords
analyte
magnetic permeability
recognition component
quantitative
measurement
Prior art date
Application number
SE9502902A
Other languages
Unknown language ( )
Swedish (sv)
Other versions
SE9502902D0 (en
SE520150C2 (en
Inventor
Dario Kriz
Kriz Christine Berggren
Original Assignee
Chemel Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemel Ab filed Critical Chemel Ab
Priority to SE9502902A priority Critical patent/SE520150C2/en
Publication of SE9502902D0 publication Critical patent/SE9502902D0/en
Publication of SE9502902L publication Critical patent/SE9502902L/en
Priority to US08/847,125 priority patent/US6110660A/en
Publication of SE520150C2 publication Critical patent/SE520150C2/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)

Abstract

The analysis can be made directly on an analyte (A), which in itself has a sufficiently large magnetic permeability, so that a measurable local variation of the material constant occurs dependent upon the formation of a complex between the analyte and the recognition component (I) and which can be detected with a coil (S). The analyte contains a ferromagnetic material (M). The analysis can also be made on an analyte which has low magnetic permeability, whereby a marker (B) with a sufficiently large magnetic permeability is allowed to bind (covalent or non-covalent) to the analyser, either before or after the binding of the analyte to the recognition component, thus inducing measurable local variations of the material constant, dependent upon the formation of a complex between the analyte coupled to the marker and the recognition component. The analyte-binding marker contains partly a ferromagnetic material and partly a binding substance (C) which is directed towards an epitope on the analyte other than that towards which the recognition component is direct.
SE9502902A 1995-08-20 1995-08-20 Quantitative and qualitative analysis of chemical substances SE520150C2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
SE9502902A SE520150C2 (en) 1995-08-20 1995-08-20 Quantitative and qualitative analysis of chemical substances
US08/847,125 US6110660A (en) 1995-08-20 1997-05-01 Procedure for quantitative and qualitative determination of chemical substances, based on molecular recognition and measurement of magnetic permeability

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9502902A SE520150C2 (en) 1995-08-20 1995-08-20 Quantitative and qualitative analysis of chemical substances

Publications (3)

Publication Number Publication Date
SE9502902D0 SE9502902D0 (en) 1995-08-20
SE9502902L true SE9502902L (en) 1997-02-21
SE520150C2 SE520150C2 (en) 2003-06-03

Family

ID=20399240

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9502902A SE520150C2 (en) 1995-08-20 1995-08-20 Quantitative and qualitative analysis of chemical substances

Country Status (1)

Country Link
SE (1) SE520150C2 (en)

Also Published As

Publication number Publication date
SE9502902D0 (en) 1995-08-20
SE520150C2 (en) 2003-06-03

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SE9502902L (en) Method for quantitative and qualitative determination of chemical substances whose functional principle is based on molecular recognition and measurement of the magnetic permeability

Legal Events

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NUG Patent has lapsed