SE9302198D0 - POWDER PREPARATION FOR INHALATION - Google Patents

POWDER PREPARATION FOR INHALATION

Info

Publication number
SE9302198D0
SE9302198D0 SE9302198A SE9302198A SE9302198D0 SE 9302198 D0 SE9302198 D0 SE 9302198D0 SE 9302198 A SE9302198 A SE 9302198A SE 9302198 A SE9302198 A SE 9302198A SE 9302198 D0 SE9302198 D0 SE 9302198D0
Authority
SE
Sweden
Prior art keywords
polypeptide
particles
absorption
promoter
inhalation
Prior art date
Application number
SE9302198A
Other languages
Swedish (sv)
Inventor
*Baeckstroem Kjell
*Dahlbaeck Magnus
*Edman Peter
*Johansson Ann
Original Assignee
Ab Astra
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ab Astra filed Critical Ab Astra
Priority to SE9302198A priority Critical patent/SE9302198D0/en
Publication of SE9302198D0 publication Critical patent/SE9302198D0/en
Priority to ZA944378A priority patent/ZA944378B/en
Priority to TW083105540A priority patent/TW402506B/en
Priority to ZA944379A priority patent/ZA944379B/en
Priority to IS4178A priority patent/IS1768B/en
Priority to IS4179A priority patent/IS1796B/en
Priority to IL11008494A priority patent/IL110084A/en
Priority to EG36694A priority patent/EG20599A/en
Priority to MYPI94001613A priority patent/MY114125A/en
Priority to EG36794A priority patent/EG21484A/en
Priority to IL11008594A priority patent/IL110085A/en
Priority to AU70901/94A priority patent/AU692780B2/en
Priority to US08265372 priority patent/US5518998C1/en
Priority to NZ268138A priority patent/NZ268138A/en
Priority to BR9406907A priority patent/BR9406907A/en
Priority to UA95125418A priority patent/UA48111C2/en
Priority to PT94919961T priority patent/PT706383E/en
Priority to CA002166109A priority patent/CA2166109C/en
Priority to UA95125417A priority patent/UA49794C2/en
Priority to ES94919960T priority patent/ES2138087T3/en
Priority to JP7502737A priority patent/JPH09500621A/en
Priority to PCT/SE1994/000633 priority patent/WO1995000127A1/en
Priority to PCT/SE1994/000634 priority patent/WO1995000128A1/en
Priority to DK94919960T priority patent/DK0706382T3/en
Priority to MYPI94001630A priority patent/MY112098A/en
Priority to AU70902/94A priority patent/AU692781B2/en
Priority to DE69428442T priority patent/DE69428442T2/en
Priority to JP50273695A priority patent/JP3874789B2/en
Priority to CN94192867A priority patent/CN1116030C/en
Priority to CN94193190A priority patent/CN1110301C/en
Priority to PL94312210A priority patent/PL178261B1/en
Priority to DE69420412T priority patent/DE69420412T2/en
Priority to AT94919961T priority patent/ATE206046T1/en
Priority to RU96102841A priority patent/RU2159108C2/en
Priority to HU9503660A priority patent/HU226474B1/en
Priority to KR1019950705904A priority patent/KR100372673B1/en
Priority to BR9406908A priority patent/BR9406908A/en
Priority to CA002166108A priority patent/CA2166108C/en
Priority to PL94312205A priority patent/PL178403B1/en
Priority to RU96103636A priority patent/RU2148398C1/en
Priority to SK1601-95A priority patent/SK283145B6/en
Priority to CZ19953428A priority patent/CZ287314B6/en
Priority to US08265371 priority patent/US5506203C1/en
Priority to EP94919961A priority patent/EP0706383B1/en
Priority to ES94919961T priority patent/ES2162865T3/en
Priority to EP94919960A priority patent/EP0706382B1/en
Priority to CZ19953393A priority patent/CZ287656B6/en
Priority to HU9503659A priority patent/HU228129B1/en
Priority to MX9404761A priority patent/MX9404761A/en
Priority to SK1602-95A priority patent/SK283253B6/en
Priority to AT94919960T priority patent/ATE183920T1/en
Priority to MX9404762A priority patent/MX9404762A/en
Priority to KR1019950705905A priority patent/KR100372674B1/en
Priority to DK94919961T priority patent/DK0706383T3/en
Priority to NZ268137A priority patent/NZ268137A/en
Priority to LTIP1976A priority patent/LT3649B/en
Priority to NZ328475A priority patent/NZ328475A/en
Priority to LTIP1977A priority patent/LT3445B/en
Priority to SA94150030A priority patent/SA94150030B1/en
Priority to SA94150060A priority patent/SA94150060B1/en
Priority to EE9400429A priority patent/EE03221B1/en
Priority to EE9400457A priority patent/EE03222B1/en
Priority to US08/471,488 priority patent/US5658878A/en
Priority to NO19955227A priority patent/NO313080B1/en
Priority to NO19955226A priority patent/NO313657B1/en
Priority to FI956227A priority patent/FI111688B/en
Priority to FI956228A priority patent/FI111909B/en
Priority to US08/583,205 priority patent/US5747445A/en
Priority to US08/736,267 priority patent/US6794357B1/en
Priority to US08/858,122 priority patent/US5952008A/en
Priority to NZ328476A priority patent/NZ328476A/en
Priority to US08/906,825 priority patent/US6306440B1/en
Priority to US08/960,093 priority patent/US6632456B1/en
Priority to HK98110295A priority patent/HK1009584A1/en
Priority to HK98110333A priority patent/HK1009587A1/en
Priority to US09/158,554 priority patent/US6846801B1/en
Priority to GR990403067T priority patent/GR3031974T3/en
Priority to US09/731,429 priority patent/US20010003739A1/en
Priority to US10/401,157 priority patent/US20030211972A1/en
Priority to US10/401,181 priority patent/US20030216541A1/en
Priority to US10/792,201 priority patent/US20040171550A1/en
Priority to JP2005325056A priority patent/JP4294635B2/en
Priority to JP2005325089A priority patent/JP2006089497A/en

Links

Landscapes

  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

respiratory alleviation preparations. SUBSTANCE: composition in the form of dry powder contains pharmaceutically-active polypeptide associated with surfactant-type promoter. The latter increases absorption of polypeptide in lower respiratory pathways. Its amount represents more than 10% of the total weight of polypeptide and promoter. At least 50% of powder consists of particles with diameter lesser than or equal to 10 mcm, or agglomerates of these particles. Inhaled composition provides system transportation of therapeutically-active peptides and proteins into lungs and absorption of drugs. EFFECT: enhanced treatment efficiency. 31 cl, 3 dwg, 1 tbl, 4 ex
SE9302198A 1993-06-24 1993-06-24 POWDER PREPARATION FOR INHALATION SE9302198D0 (en)

Priority Applications (83)

Application Number Priority Date Filing Date Title
SE9302198A SE9302198D0 (en) 1993-06-24 1993-06-24 POWDER PREPARATION FOR INHALATION
ZA944378A ZA944378B (en) 1993-06-24 1994-06-20 Therapeutic preparation for inhalation
TW083105540A TW402506B (en) 1993-06-24 1994-06-20 Therapeutic preparation for inhalation
ZA944379A ZA944379B (en) 1993-06-24 1994-06-20 Compositions for inhalation
IS4178A IS1768B (en) 1993-06-24 1994-06-21 Inhalant pharmaceutical composition containing insulin
IS4179A IS1796B (en) 1993-06-24 1994-06-21 Inhaled polypeptide formulation composition which also contains an enhancer compound
IL11008494A IL110084A (en) 1993-06-24 1994-06-22 Therapeutic preparation for inhalation of insulin and process for its preparation
EG36694A EG20599A (en) 1993-06-24 1994-06-22 Powder preparation for inhalation
MYPI94001613A MY114125A (en) 1993-06-24 1994-06-22 Compositions for inhalation
EG36794A EG21484A (en) 1993-06-24 1994-06-22 Composition for inhalation
IL11008594A IL110085A (en) 1993-06-24 1994-06-22 Pharmaceutical compositions for inhalation of active polypeptides and a process for their preparation
AU70901/94A AU692780B2 (en) 1993-06-24 1994-06-23 Therapeutic preparation for inhalation
US08265372 US5518998C1 (en) 1993-06-24 1994-06-23 Therapeutic preparation for inhalation
NZ268138A NZ268138A (en) 1993-06-24 1994-06-23 Preparation of a pharmaceutically active polypeptide and a substance enhancing its absorption in the lower respiratory tract in the form of a dry powder suitable for inhalation
BR9406907A BR9406907A (en) 1993-06-24 1994-06-23 Therapeutic preparation use of the same dry powder inhaler device dry powder inhaler and use of a improving agent in the preparation of an inhalable dry powder preparation
UA95125418A UA48111C2 (en) 1993-06-24 1994-06-23 Pharmaceutical composition for inhalation, method for manufacturing (variants) and inhaler
PT94919961T PT706383E (en) 1993-06-24 1994-06-23 INHALATION COMPOSITIONS
CA002166109A CA2166109C (en) 1993-06-24 1994-06-23 Compositions for inhalation
UA95125417A UA49794C2 (en) 1993-06-24 1994-06-23 Therapeutic preparation of insulin for inhalation (variants), method for preparation (variants), disposable inhalator (variants)
ES94919960T ES2138087T3 (en) 1993-06-24 1994-06-23 THERAPEUTIC PREPARATION FOR INHALATION.
JP7502737A JPH09500621A (en) 1993-06-24 1994-06-23 Inhalation composition
PCT/SE1994/000633 WO1995000127A1 (en) 1993-06-24 1994-06-23 Therapeutic preparation for inhalation
PCT/SE1994/000634 WO1995000128A1 (en) 1993-06-24 1994-06-23 Compositions for inhalation
DK94919960T DK0706382T3 (en) 1993-06-24 1994-06-23 Therapeutic preparation for inhalation
MYPI94001630A MY112098A (en) 1993-06-24 1994-06-23 Therapeutic preparation for inhalation
AU70902/94A AU692781B2 (en) 1993-06-24 1994-06-23 Compositions for inhalation
DE69428442T DE69428442T2 (en) 1993-06-24 1994-06-23 Inhalation PREPARATIONS
JP50273695A JP3874789B2 (en) 1993-06-24 1994-06-23 Inhalation treatment
CN94192867A CN1116030C (en) 1993-06-24 1994-06-23 Compositions for inhalation
CN94193190A CN1110301C (en) 1993-06-24 1994-06-23 Therapeutic preparation for inhalation
PL94312210A PL178261B1 (en) 1993-06-24 1994-06-23 Inhalable compositions
DE69420412T DE69420412T2 (en) 1993-06-24 1994-06-23 THERAPEUTIC INHALATION PRODUCT
AT94919961T ATE206046T1 (en) 1993-06-24 1994-06-23 INHALATION PREPARATIONS
RU96102841A RU2159108C2 (en) 1993-06-24 1994-06-23 Inhalation composition
HU9503660A HU226474B1 (en) 1993-06-24 1994-06-23 Compositions for inhalation comprising a pharmaceutical active polypeptide and enhancer compound and process for prepearing them
KR1019950705904A KR100372673B1 (en) 1993-06-24 1994-06-23 Insulin Therapy
BR9406908A BR9406908A (en) 1993-06-24 1994-06-23 Pharmaceutical composition inhaler device process for administering a pharmaceutically active polypeptide system for the manufacture and preparation of a pharmaceutical composition and the use of an improving agent in the preparation of an inhalable dry powder preparation
CA002166108A CA2166108C (en) 1993-06-24 1994-06-23 Insulin preparations for inhalation
PL94312205A PL178403B1 (en) 1993-06-24 1994-06-23 Inhalable therapeutic preparation
RU96103636A RU2148398C1 (en) 1993-06-24 1994-06-23 Therapeutic preparation and method for making inhalations
SK1601-95A SK283145B6 (en) 1993-06-24 1994-06-23 Therapeutic preparation for inhalation
CZ19953428A CZ287314B6 (en) 1993-06-24 1994-06-23 Therapeutic preparation for administering insulin by inhalation and process for preparing thereof
US08265371 US5506203C1 (en) 1993-06-24 1994-06-23 Systemic administration of a therapeutic preparation
EP94919961A EP0706383B1 (en) 1993-06-24 1994-06-23 Compositions for inhalation
ES94919961T ES2162865T3 (en) 1993-06-24 1994-06-23 COMPOSITIONS FOR INHALATION.
EP94919960A EP0706382B1 (en) 1993-06-24 1994-06-23 Therapeutic preparation for inhalation
CZ19953393A CZ287656B6 (en) 1993-06-24 1994-06-23 Pharmaceutical preparation in the form of dry powder intended for inhalation
HU9503659A HU228129B1 (en) 1993-06-24 1994-06-23 Therapeutic preparation for inhalation
MX9404761A MX9404761A (en) 1993-06-24 1994-06-23 THERAPEUTIC PREPARATION FOR INHALATION AND PROCESS FOR ITS ELABORATION.
SK1602-95A SK283253B6 (en) 1993-06-24 1994-06-23 Pharmaceutical compositions for inhalation
AT94919960T ATE183920T1 (en) 1993-06-24 1994-06-23 THERAPEUTIC INHALATION PREPARATION
MX9404762A MX9404762A (en) 1993-06-24 1994-06-23 COMPOSITIONS FOR INHALATION AND PROCESS FOR ITS PREPARATION.
KR1019950705905A KR100372674B1 (en) 1993-06-24 1994-06-23 Polypeptide inhalation composition
DK94919961T DK0706383T3 (en) 1993-06-24 1994-06-23 Preparation for inhalation
NZ268137A NZ268137A (en) 1993-06-24 1994-06-23 Preparation of insulin and a substance for enhancing its absorption in the lower respiratory tract in the form of a dry powder suitable for inhalation
LTIP1976A LT3649B (en) 1993-06-24 1994-06-24 Compositions for inhalation, method for priparing the same, using the same and inhaler
NZ328475A NZ328475A (en) 1993-06-24 1994-06-24 A pharmaceutical composition containing a polypeptide up to 40 kD and an enhancer for systemic delivery by inhalation
LTIP1977A LT3445B (en) 1993-06-24 1994-06-24 Therapeutic preparation for inhalation
SA94150030A SA94150030B1 (en) 1993-06-24 1994-06-27 Inhalation medicine
SA94150060A SA94150060B1 (en) 1993-06-24 1994-07-05 Composition for inhalation
EE9400429A EE03221B1 (en) 1993-06-24 1994-11-23 Pharmaceutical formulations for inhalation, the process for their preparation and the inhaler for their use
EE9400457A EE03222B1 (en) 1993-06-24 1994-11-23 Pharmaceutical formulations for inhalation, the process for their preparation and the device for their application
US08/471,488 US5658878A (en) 1993-06-24 1995-06-06 Therapeutic preparation for inhalation
NO19955227A NO313080B1 (en) 1993-06-24 1995-12-21 Pharmaceutical inhalation composition, inhalation device containing it, process for its preparation and use thereof
NO19955226A NO313657B1 (en) 1993-06-24 1995-12-21 Therapeutic preparation for inhalation, method of preparation thereof, use of an amplifier, and dry powder inhaler
FI956227A FI111688B (en) 1993-06-24 1995-12-22 Process for the preparation of a therapeutic dry powder formulation of insulin
FI956228A FI111909B (en) 1993-06-24 1995-12-22 A method of preparing compositions for inhalation
US08/583,205 US5747445A (en) 1993-06-24 1996-01-04 Therapeutic preparation for inhalation
US08/736,267 US6794357B1 (en) 1993-06-24 1996-10-24 Compositions for inhalation
US08/858,122 US5952008A (en) 1993-06-24 1997-05-19 Processes for preparing compositions for inhalation
NZ328476A NZ328476A (en) 1993-06-24 1997-07-31 Use of a two component insulin preparation in an inhalation device
US08/906,825 US6306440B1 (en) 1993-06-24 1997-08-06 Therapeutic preparation for inhalation
US08/960,093 US6632456B1 (en) 1993-06-24 1997-10-24 Compositions for inhalation
HK98110295A HK1009584A1 (en) 1993-06-24 1998-08-29 Therapeutic preparation for inhalation
HK98110333A HK1009587A1 (en) 1993-06-24 1998-09-01 Compositions for inhalation
US09/158,554 US6846801B1 (en) 1993-06-24 1998-09-22 Systemic administration of a therapeutic preparation
GR990403067T GR3031974T3 (en) 1993-06-24 1999-11-29 Therapeutic preparation for inhalation
US09/731,429 US20010003739A1 (en) 1993-06-24 2000-12-06 Systemic administration of a therapeutic preparation
US10/401,157 US20030211972A1 (en) 1993-06-24 2003-03-27 Systemic administration of a therapeutic preparation
US10/401,181 US20030216541A1 (en) 1993-06-24 2003-03-27 Systemic administration of a therapeutic preparation
US10/792,201 US20040171550A1 (en) 1993-06-24 2004-03-03 Compositions for inhalation
JP2005325056A JP4294635B2 (en) 1993-06-24 2005-11-09 Inhalation treatment
JP2005325089A JP2006089497A (en) 1993-06-24 2005-11-09 Compositions for inhalation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9302198A SE9302198D0 (en) 1993-06-24 1993-06-24 POWDER PREPARATION FOR INHALATION

Publications (1)

Publication Number Publication Date
SE9302198D0 true SE9302198D0 (en) 1993-06-24

Family

ID=20390412

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9302198A SE9302198D0 (en) 1993-06-24 1993-06-24 POWDER PREPARATION FOR INHALATION

Country Status (4)

Country Link
LT (2) LT3649B (en)
RU (1) RU2159108C2 (en)
SE (1) SE9302198D0 (en)
ZA (2) ZA944378B (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH636011A5 (en) 1978-01-01 1983-05-13 Sandoz Ag Administration forms for organic compounds

Also Published As

Publication number Publication date
ZA944379B (en) 1995-03-24
LTIP1976A (en) 1995-05-25
RU2159108C2 (en) 2000-11-20
LT3649B (en) 1996-01-25
ZA944378B (en) 1995-03-24
LT3445B (en) 1995-10-25
LTIP1977A (en) 1995-01-31

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