SE9301732D0 - NEW CENTRALLY ACTING 5-, 6-, 7-, AND 8-SUBSTITUTED SULPHONE ESTERS OF N-MONOSUBSTITUTED 2-AMINOTETRALINS - Google Patents
NEW CENTRALLY ACTING 5-, 6-, 7-, AND 8-SUBSTITUTED SULPHONE ESTERS OF N-MONOSUBSTITUTED 2-AMINOTETRALINSInfo
- Publication number
- SE9301732D0 SE9301732D0 SE9301732A SE9301732A SE9301732D0 SE 9301732 D0 SE9301732 D0 SE 9301732D0 SE 9301732 A SE9301732 A SE 9301732A SE 9301732 A SE9301732 A SE 9301732A SE 9301732 D0 SE9301732 D0 SE 9301732D0
- Authority
- SE
- Sweden
- Prior art keywords
- aminotetralins
- monosubstituted
- esters
- centrally acting
- new centrally
- Prior art date
Links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A compound of formula (1) or pharmaceutically acceptable acid addition salts thereof, wherein R1 is H, (C1-C8) alkyl, alkenyl, alkynyl, cyclopropylalkyl or (C1-C8) haloalkyl; X is CH2, O or S; R2-SO2-O is in position 5, 6, 7 or 8 and R2 is CF3, CF2CF3, C1-C8 alkyl, substituted aryl (e.g. 4-toluyl); R3 is H, CH3 or CH2CH3. When R3 is CH3 or CH2CH3, it is always in a cis-relationship with respect to the 2-amine substituent.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9301732A SE9301732D0 (en) | 1993-05-18 | 1993-05-18 | NEW CENTRALLY ACTING 5-, 6-, 7-, AND 8-SUBSTITUTED SULPHONE ESTERS OF N-MONOSUBSTITUTED 2-AMINOTETRALINS |
PCT/SE1994/000465 WO1994026703A1 (en) | 1993-05-18 | 1994-05-18 | New centrally acting 5-, 6-, 7-, and 8-substituted sulphone esters of n-monosubstituted 2-aminotetralins and related structures |
AU68110/94A AU6811094A (en) | 1993-05-18 | 1994-05-18 | New centrally acting 5-, 6-, 7-, and 8-substituted sulphone esters of n-monosubstituted 2-aminotetralins and related structures |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9301732A SE9301732D0 (en) | 1993-05-18 | 1993-05-18 | NEW CENTRALLY ACTING 5-, 6-, 7-, AND 8-SUBSTITUTED SULPHONE ESTERS OF N-MONOSUBSTITUTED 2-AMINOTETRALINS |
Publications (1)
Publication Number | Publication Date |
---|---|
SE9301732D0 true SE9301732D0 (en) | 1993-05-18 |
Family
ID=20390003
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE9301732A SE9301732D0 (en) | 1993-05-18 | 1993-05-18 | NEW CENTRALLY ACTING 5-, 6-, 7-, AND 8-SUBSTITUTED SULPHONE ESTERS OF N-MONOSUBSTITUTED 2-AMINOTETRALINS |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU6811094A (en) |
SE (1) | SE9301732D0 (en) |
WO (1) | WO1994026703A1 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9601110D0 (en) | 1996-03-22 | 1996-03-22 | Astra Ab | Substituted 1,2,3,4-tetrahydronaphthalene derivatives |
DE10334188B4 (en) | 2003-07-26 | 2007-07-05 | Schwarz Pharma Ag | Use of rotigotine to treat depression |
DE10359528A1 (en) | 2003-12-18 | 2005-07-28 | Schwarz Pharma Ag | (S) -2-N-propylamino-5-hydroxytetralin as a D3 agonist therapeutic |
DE10361258A1 (en) | 2003-12-24 | 2005-07-28 | Schwarz Pharma Ag | Use of substituted 2-aminotetralins for the preventive treatment of Parkinson's disease |
DE102004014841B4 (en) | 2004-03-24 | 2006-07-06 | Schwarz Pharma Ag | Use of rotigotine for the treatment and prevention of Parkinson-Plus syndrome |
GB0426061D0 (en) * | 2004-11-26 | 2004-12-29 | Pfizer Ltd | Chroman compounds |
EP2215072B1 (en) | 2007-11-28 | 2015-09-02 | UCB Pharma GmbH | Polymorphic form of rotigotine |
IT1392387B1 (en) * | 2008-09-26 | 2012-03-02 | Solmag S P A Ora Fidia Farmaceutici S P A | PROCESS FOR ROTIGOTINE PREPARATION |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE8605504D0 (en) * | 1986-12-19 | 1986-12-19 | Astra Laekemedel Ab | NOVEL CHROMAN DERIVATIVES |
ZA901277B (en) * | 1989-02-27 | 1991-10-30 | Lilly Co Eli | Ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes and 3-aminochromanes |
SE8901889D0 (en) * | 1989-05-26 | 1989-05-26 | Astra Ab | NOVEL 8-SUBSTITUTED-2-AMINOTETRALINES |
WO1992006967A1 (en) * | 1990-10-12 | 1992-04-30 | The Upjohn Company | Therapeutically useful 2-aminotetralin derivatives |
SE8904361D0 (en) * | 1989-12-22 | 1989-12-22 | Astra Ab | NEW CHROMAN AND THIOCHROMAN DERIVATIVES |
-
1993
- 1993-05-18 SE SE9301732A patent/SE9301732D0/en unknown
-
1994
- 1994-05-18 AU AU68110/94A patent/AU6811094A/en not_active Abandoned
- 1994-05-18 WO PCT/SE1994/000465 patent/WO1994026703A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
AU6811094A (en) | 1994-12-12 |
WO1994026703A1 (en) | 1994-11-24 |
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