SE8903985L - Peptide(s) corresp. to HIV-1 P17 C-terminal - used for discriminating between a false and true diagnosed HIV-1 positive serum sample - Google Patents

Peptide(s) corresp. to HIV-1 P17 C-terminal - used for discriminating between a false and true diagnosed HIV-1 positive serum sample

Info

Publication number
SE8903985L
SE8903985L SE8903985A SE8903985A SE8903985L SE 8903985 L SE8903985 L SE 8903985L SE 8903985 A SE8903985 A SE 8903985A SE 8903985 A SE8903985 A SE 8903985A SE 8903985 L SE8903985 L SE 8903985L
Authority
SE
Sweden
Prior art keywords
ala
hiv
ser
asn
gln
Prior art date
Application number
SE8903985A
Other languages
Swedish (sv)
Other versions
SE8903985D0 (en
Inventor
J Blomberg
Original Assignee
Replico Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Replico Ab filed Critical Replico Ab
Priority to SE8903985A priority Critical patent/SE8903985L/en
Publication of SE8903985D0 publication Critical patent/SE8903985D0/en
Priority to SE9000356A priority patent/SE9000356L/en
Priority to AU68875/91A priority patent/AU6887591A/en
Priority to PCT/SE1990/000756 priority patent/WO1991008227A1/en
Publication of SE8903985L publication Critical patent/SE8903985L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G01N33/56988—HIV or HTLV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • AIDS & HIV (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

10 Peptides of formula, e.g. (I)-(III) are new.@ H-X-Ala-Ala-Ala-Asp-Thr-Gly-His-Ser-Asn-Gln-Val-Ser-Gln-Asn-Tyr-X-Z (I);@ H-X-Ala-Ala-Ala-Asp-Thr-Gly-His-Ser-Ser-Gln-Val-Ser-Gln-Asn-Tyr-X-Z (II); and @ H-X-Ala-Ala-Ala-Asp-Thr-Gly-Asn-Asn-Ser-Gln-Val-Ser-Glu-Asn-Tyr-X-Z (III)@ (X is a chemical bond or a coupling-facilitating amino acid sequence; Z = NH2 or OH). Also claimed is a method of discriminating between a false and true diagnosed HIV-1 positive serum sample, characterised in that at least one diagnostic antigen having the ability of binding to antibodies which have a binding affinity for cpds. contg. an amino acid sequence corresp. to an epitope or clusters of epitopes of HIV-1 p17, opt. coupled to a carrier, is added to the serum sample and that possible antigen/antibody complexes formed are detected using an immunoassay, whereby the discrimination is established based upon that the serum sample is false HIV-I positive if the complexes are detected and true HIV-1 positive if the complexes are not detected.
SE8903985A 1989-11-27 1989-11-27 Peptide(s) corresp. to HIV-1 P17 C-terminal - used for discriminating between a false and true diagnosed HIV-1 positive serum sample SE8903985L (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
SE8903985A SE8903985L (en) 1989-11-27 1989-11-27 Peptide(s) corresp. to HIV-1 P17 C-terminal - used for discriminating between a false and true diagnosed HIV-1 positive serum sample
SE9000356A SE9000356L (en) 1989-11-27 1990-02-01 Peptide(s) corresp. to HIV-1 P17 C-terminal - used for discriminating between a false and true diagnosed HIV-1 positive serum sample
AU68875/91A AU6887591A (en) 1989-11-27 1990-11-22 New hiv-1 p17 peptides, diagnostic antigens and immunoassay method
PCT/SE1990/000756 WO1991008227A1 (en) 1989-11-27 1990-11-22 NEW HIV-1 p17 PEPTIDES, DIAGNOSTIC ANTIGENS AND IMMUNOASSAY METHOD

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8903985A SE8903985L (en) 1989-11-27 1989-11-27 Peptide(s) corresp. to HIV-1 P17 C-terminal - used for discriminating between a false and true diagnosed HIV-1 positive serum sample

Publications (2)

Publication Number Publication Date
SE8903985D0 SE8903985D0 (en) 1989-11-27
SE8903985L true SE8903985L (en) 1991-05-28

Family

ID=20377599

Family Applications (2)

Application Number Title Priority Date Filing Date
SE8903985A SE8903985L (en) 1989-11-27 1989-11-27 Peptide(s) corresp. to HIV-1 P17 C-terminal - used for discriminating between a false and true diagnosed HIV-1 positive serum sample
SE9000356A SE9000356L (en) 1989-11-27 1990-02-01 Peptide(s) corresp. to HIV-1 P17 C-terminal - used for discriminating between a false and true diagnosed HIV-1 positive serum sample

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE9000356A SE9000356L (en) 1989-11-27 1990-02-01 Peptide(s) corresp. to HIV-1 P17 C-terminal - used for discriminating between a false and true diagnosed HIV-1 positive serum sample

Country Status (1)

Country Link
SE (2) SE8903985L (en)

Also Published As

Publication number Publication date
SE8903985D0 (en) 1989-11-27
SE9000356D0 (en) 1990-02-01
SE9000356L (en) 1991-05-28

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