SE8901566D0 - NEW PEPTIDES INCLUDING A DISULFID BOND - Google Patents
NEW PEPTIDES INCLUDING A DISULFID BONDInfo
- Publication number
- SE8901566D0 SE8901566D0 SE8901566A SE8901566A SE8901566D0 SE 8901566 D0 SE8901566 D0 SE 8901566D0 SE 8901566 A SE8901566 A SE 8901566A SE 8901566 A SE8901566 A SE 8901566A SE 8901566 D0 SE8901566 D0 SE 8901566D0
- Authority
- SE
- Sweden
- Prior art keywords
- antigen
- artificial
- human parvovirus
- epitope
- amino acid
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 239000000427 antigen Substances 0.000 abstract 5
- 102000036639 antigens Human genes 0.000 abstract 5
- 108091007433 antigens Proteins 0.000 abstract 5
- 241000484121 Human parvovirus Species 0.000 abstract 3
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 2
- 125000000151 cysteine group Chemical group N[C@@H](CS)C(=O)* 0.000 abstract 2
- 238000003018 immunoassay Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 238000002965 ELISA Methods 0.000 abstract 1
- 239000005864 Sulphur Substances 0.000 abstract 1
- 210000001124 body fluid Anatomy 0.000 abstract 1
- 239000010839 body fluid Substances 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14211—Erythrovirus, e.g. B19 virus
- C12N2750/14222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Abstract
An artificial peptide having an amino acid sequence which corresponds to a naturally occurring amino acid sequence of a human parvovirus comprising an epitope and which further has two cysteine residues located on each side of said epitope, and further having a sulphur bridge between said two cysteine residues, which has been formed by a chemical oxidation step, is described. Furthermore, an artificial antigen which reacts with antibodies induced by a human parvovirus is described. Said antigen mainly consists of an artificial peptide according to the invention. Additionally, a method of detecting antibodies induced by a human parvovirus in a sample of body fluid, wherein said sample is subjected to an immunoassay, especially ELISA, and wherein an artificial antigen according to the invention is used as a diagnostic antigen, is described. A diagnostic immunoassay kit for said method is also described. Finally, a vaccine composition comprising, as an immunizing component, at least one antigen according to the invention, is described.
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8901566A SE8901566D0 (en) | 1989-04-28 | 1989-04-28 | NEW PEPTIDES INCLUDING A DISULFID BOND |
AU55596/90A AU636145B2 (en) | 1989-04-28 | 1990-04-25 | New human parvovirus peptides with disulfide bridge for immunization or diagnosis |
EP90908131A EP0470205A1 (en) | 1989-04-28 | 1990-04-25 | New human parvovirus peptides with disulfide bridge for immunization or diagnosis |
CA002053240A CA2053240A1 (en) | 1989-04-28 | 1990-04-25 | Human parvovirus peptides with disulfide bridge for immunization or diagnosis |
PCT/SE1990/000276 WO1990013567A1 (en) | 1989-04-28 | 1990-04-25 | New human parvovirus peptides with disulfide bridge for immunization or diagnosis |
IL94218A IL94218A0 (en) | 1989-04-28 | 1990-04-26 | Peptides including a disulfide bond,their use in diagnosis and vaccine compositions containing them |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8901566A SE8901566D0 (en) | 1989-04-28 | 1989-04-28 | NEW PEPTIDES INCLUDING A DISULFID BOND |
Publications (1)
Publication Number | Publication Date |
---|---|
SE8901566D0 true SE8901566D0 (en) | 1989-04-28 |
Family
ID=20375840
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8901566A SE8901566D0 (en) | 1989-04-28 | 1989-04-28 | NEW PEPTIDES INCLUDING A DISULFID BOND |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0470205A1 (en) |
AU (1) | AU636145B2 (en) |
CA (1) | CA2053240A1 (en) |
IL (1) | IL94218A0 (en) |
SE (1) | SE8901566D0 (en) |
WO (1) | WO1990013567A1 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6274307B1 (en) * | 1990-02-08 | 2001-08-14 | Mikrogen Molekularbiologische Entwicklungs-Gmbh | Immunologically active peptides or polypeptides from the parvovirus B19 |
US5244785A (en) * | 1991-02-01 | 1993-09-14 | Microgenics Corporation | Determination of high molecular weight analytes using a β-galactosidase complementation assay |
JPH0910000A (en) | 1995-06-26 | 1997-01-14 | Nippon Sekijiyuujishiya | Detection of human parvovirus and reagent therefor |
US6238860B1 (en) | 1998-11-05 | 2001-05-29 | Dyax Corp. | Binding moieties for human parvovirus B19 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL70704A0 (en) * | 1983-01-19 | 1984-04-30 | Amgen | Methods and materials for development of parvovirus vaccines |
DE3782350D1 (en) * | 1986-03-20 | 1992-12-03 | Abbott Lab | RECOMBINANT PARVOVIRUS RA-1 PRODUCTS AND METHOD FOR USE THEREOF. |
-
1989
- 1989-04-28 SE SE8901566A patent/SE8901566D0/en unknown
-
1990
- 1990-04-25 CA CA002053240A patent/CA2053240A1/en not_active Abandoned
- 1990-04-25 EP EP90908131A patent/EP0470205A1/en not_active Withdrawn
- 1990-04-25 WO PCT/SE1990/000276 patent/WO1990013567A1/en not_active Application Discontinuation
- 1990-04-25 AU AU55596/90A patent/AU636145B2/en not_active Expired - Fee Related
- 1990-04-26 IL IL94218A patent/IL94218A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP0470205A1 (en) | 1992-02-12 |
AU636145B2 (en) | 1993-04-22 |
WO1990013567A1 (en) | 1990-11-15 |
IL94218A0 (en) | 1991-01-31 |
AU5559690A (en) | 1990-11-29 |
CA2053240A1 (en) | 1990-10-29 |
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