SE8901115D0 - BIOLOGICALLY ACTIVE PROTEINS - Google Patents

BIOLOGICALLY ACTIVE PROTEINS

Info

Publication number
SE8901115D0
SE8901115D0 SE8901115A SE8901115A SE8901115D0 SE 8901115 D0 SE8901115 D0 SE 8901115D0 SE 8901115 A SE8901115 A SE 8901115A SE 8901115 A SE8901115 A SE 8901115A SE 8901115 D0 SE8901115 D0 SE 8901115D0
Authority
SE
Sweden
Prior art keywords
biologically active
active proteins
proteins
febule
tnf
Prior art date
Application number
SE8901115A
Other languages
Swedish (sv)
Other versions
SE8901115L (en
Inventor
J-M Dayer
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of SE8901115D0 publication Critical patent/SE8901115D0/en
Publication of SE8901115L publication Critical patent/SE8901115L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

A protein having a selective tumour necrosis factor (TNF)- alpha inhibitory activity, but which does not block other proteins, particularly IL-1, is prepared by extraction from urine of febule patients.
SE8901115A 1988-03-31 1989-03-30 BIOLOGICALLY ACTIVE PROTEINS SE8901115L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888807803A GB8807803D0 (en) 1988-03-31 1988-03-31 Biochemical product

Publications (2)

Publication Number Publication Date
SE8901115D0 true SE8901115D0 (en) 1989-03-30
SE8901115L SE8901115L (en) 1989-10-01

Family

ID=10634493

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8901115A SE8901115L (en) 1988-03-31 1989-03-30 BIOLOGICALLY ACTIVE PROTEINS

Country Status (12)

Country Link
JP (1) JPH02117700A (en)
KR (1) KR890014125A (en)
AU (1) AU3228789A (en)
BE (1) BE1001845A4 (en)
DE (1) DE3910323A1 (en)
DK (1) DK156589A (en)
FR (1) FR2629345A1 (en)
GB (2) GB8807803D0 (en)
IL (1) IL89804A0 (en)
IT (1) IT1232827B (en)
NL (1) NL8900779A (en)
SE (1) SE8901115L (en)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL83878A (en) * 1987-09-13 1995-07-31 Yeda Res & Dev Soluble protein corresponding to tnf inhibitory protein its preparation and pharmaceutical compositions containing it
US5811261A (en) * 1988-09-12 1998-09-22 Yeda Research And Development Co. Ltd. Expression of the recombinant tumor necrosis factor binding protein I (TBP-I)
US6221675B1 (en) 1989-04-21 2001-04-24 Amgen, Inc. TNF receptors, TNF binding proteins and DNAs coding for them
ATE289350T1 (en) * 1989-04-21 2005-03-15 Amgen Inc TNF RECEPTOR, TNF BINDING PROTEINS AND DNA CODING THEREOF
US7264944B1 (en) 1989-04-21 2007-09-04 Amgen Inc. TNF receptors, TNF binding proteins and DNAs coding for them
US6143866A (en) * 1989-07-18 2000-11-07 Amgen, Inc. Tumor necrosis factor (TNF) inhibitor and method for obtaining the same
IL95031A (en) * 1989-07-18 2007-03-08 Amgen Inc Method for the production of a human recombinant tumor necrosis factor inhibitor
AU630497B2 (en) * 1989-09-05 1992-10-29 Immunex Corporation Tumor necrosis factor-alpha and -beta receptors
US5945397A (en) * 1989-09-05 1999-08-31 Immunex Corporation Purified p75 (type II) tumor necrosis factor receptor polypeptides
US5605690A (en) * 1989-09-05 1997-02-25 Immunex Corporation Methods of lowering active TNF-α levels in mammals using tumor necrosis factor receptor
US5395760A (en) * 1989-09-05 1995-03-07 Immunex Corporation DNA encoding tumor necrosis factor-α and -β receptors
EP0939121B2 (en) 1989-09-12 2007-12-26 AHP Manufacturing B.V. TNF-binding proteins
US6552170B1 (en) 1990-04-06 2003-04-22 Amgen Inc. PEGylation reagents and compounds formed therewith
WO1992001002A1 (en) * 1990-07-11 1992-01-23 Teijin Limited Tumor necrosis factor activity inhibitor and production thereof
EP0480389A1 (en) * 1990-10-12 1992-04-15 Hoechst Aktiengesellschaft Inhibitors for forming tumor necrosis factor, process for their production and their use
DK0567566T4 (en) * 1991-01-18 2007-10-22 Amgen Inc Methods for the treatment of tumor necrosis factor-mediated diseases
JPH06510122A (en) * 1991-08-23 1994-11-10 エヌチップ　インコーポレイテッド Burn-in techniques for unpackaged integrated circuits
TW555765B (en) 1996-07-09 2003-10-01 Amgen Inc Low molecular weight soluble tumor necrosis factor type-I and type-II proteins
ES2207759T3 (en) 1996-12-06 2004-06-01 Amgen Inc. COMBINATION THERAPY USING A PROTEIN OF UNION OF THE TUMOR NECROSIS FACTOR (TNF) IN THE TREATMENT OF DISEASES Induced by TNF.
JP4771563B2 (en) 1996-12-06 2011-09-14 アムジエン・インコーポレーテツド Combination therapy using IL-1 inhibitors to treat IL-1 mediated diseases
US6660843B1 (en) 1998-10-23 2003-12-09 Amgen Inc. Modified peptides as therapeutic agents
US6808902B1 (en) 1999-11-12 2004-10-26 Amgen Inc. Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
MXPA04000134A (en) 2001-06-26 2005-06-06 Abgenix Inc Antibodies to opgl.
US9028822B2 (en) 2002-06-28 2015-05-12 Domantis Limited Antagonists against TNFR1 and methods of use therefor
WO2004060911A2 (en) 2002-12-30 2004-07-22 Amgen Inc. Combination therapy with co-stimulatory factors
US7833527B2 (en) 2006-10-02 2010-11-16 Amgen Inc. Methods of treating psoriasis using IL-17 Receptor A antibodies
TW201117824A (en) 2009-10-12 2011-06-01 Amgen Inc Use of IL-17 receptor a antigen binding proteins
SI3295957T1 (en) 2010-01-15 2020-02-28 Kirin-Amgen, Inc. Anti il-17ra antibody formulation and therapeutic regimens for treating psoriasis
US20140234330A1 (en) 2011-07-22 2014-08-21 Amgen Inc. Il-17 receptor a is required for il-17c biology
CN106456751B (en) 2014-03-31 2021-02-02 安姆根K-A有限公司 Method for treating nail and scalp psoriasis

Also Published As

Publication number Publication date
JPH02117700A (en) 1990-05-02
AU3228789A (en) 1989-10-05
KR890014125A (en) 1989-10-21
BE1001845A4 (en) 1990-03-20
SE8901115L (en) 1989-10-01
GB2218101A (en) 1989-11-08
FR2629345A1 (en) 1989-10-06
GB8807803D0 (en) 1988-05-05
GB8907148D0 (en) 1989-05-10
IT8947794A0 (en) 1989-03-30
NL8900779A (en) 1989-10-16
IT1232827B (en) 1992-03-05
DK156589A (en) 1989-10-01
DE3910323A1 (en) 1989-10-19
IL89804A0 (en) 1989-09-28
DK156589D0 (en) 1989-03-30

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Legal Events

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NAV Patent application has lapsed

Ref document number: 8901115-9

Effective date: 19910424