SE8704792L - azole derivatives - Google Patents

azole derivatives

Info

Publication number
SE8704792L
SE8704792L SE8704792A SE8704792A SE8704792L SE 8704792 L SE8704792 L SE 8704792L SE 8704792 A SE8704792 A SE 8704792A SE 8704792 A SE8704792 A SE 8704792A SE 8704792 L SE8704792 L SE 8704792L
Authority
SE
Sweden
Prior art keywords
heteroaryl
aryl
substituted
cycloalkyl
mono
Prior art date
Application number
SE8704792A
Other languages
Swedish (sv)
Other versions
SE8704792D0 (en
Inventor
H Egger
R Welchli
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of SE8704792D0 publication Critical patent/SE8704792D0/en
Publication of SE8704792L publication Critical patent/SE8704792L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Compounds of formula <IMAGE> [wherein R1 and R2 are the same or different and each represent unsubstituted or mono- or poly-substituted aryl or heteroaryl; R3 represents unsubstituted or mono- or poly-substituted alkyl, cycloalkyl, aryl, or heteroaryl; or cycloalkyl, aryl or heteroaryl condensed with a benzene ring; or alkoxy; and X represents CH or N; whereby when R3 represents methyl and R1 and R2 represent phenyl at least one of said phenyls must be substituted,] in free form or in acid addition salt form are indicated for use as pharmaceuticals in particular as aromatase inhibitors.
SE8704792A 1986-12-03 1987-12-01 azole derivatives SE8704792L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3641320 1986-12-03

Publications (2)

Publication Number Publication Date
SE8704792D0 SE8704792D0 (en) 1987-12-01
SE8704792L true SE8704792L (en) 1988-06-04

Family

ID=6315380

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8704792A SE8704792L (en) 1986-12-03 1987-12-01 azole derivatives

Country Status (24)

Country Link
JP (1) JPH0678318B2 (en)
KR (1) KR880007481A (en)
AT (1) AT395587B (en)
AU (1) AU605522B2 (en)
BE (1) BE1001235A4 (en)
CH (1) CH677925A5 (en)
DK (1) DK631287A (en)
ES (1) ES2010235A6 (en)
FI (1) FI875300L (en)
FR (1) FR2607810B1 (en)
GB (1) GB2199579B (en)
GR (1) GR871897B (en)
HU (1) HU198694B (en)
IL (1) IL84665A (en)
IT (1) IT1211944B (en)
LU (1) LU87063A1 (en)
MY (1) MY103004A (en)
NL (1) NL8702897A (en)
NZ (1) NZ222765A (en)
PH (1) PH24666A (en)
PL (1) PL151588B1 (en)
PT (1) PT86255B (en)
SE (1) SE8704792L (en)
ZA (1) ZA879093B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8814277D0 (en) * 1988-06-16 1988-07-20 Glaxo Group Ltd Chemical compounds
DE69230225T2 (en) * 1991-09-02 2000-05-31 Yamanouchi Pharmaceutical Co., Ltd. TRIAZOLYLATED TERTICAL AMINE COMPOUNDS OR THEIR SALTS
GB9409882D0 (en) * 1994-05-18 1994-07-06 Sandoz Ltd Organic compounds
GB0128415D0 (en) * 2001-11-27 2002-01-16 Univ Sheffield Medicaments

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT382868B (en) * 1983-03-11 1987-04-27 Sandoz Ag Process for the preparation of novel azole derivatives and salts thereof
JPH0625144B2 (en) * 1986-02-24 1994-04-06 四国化成工業株式会社 Novel imidazole compound and method for synthesizing the compound

Also Published As

Publication number Publication date
BE1001235A4 (en) 1989-08-29
PT86255A (en) 1988-06-01
IT1211944B (en) 1989-11-08
NZ222765A (en) 1990-11-27
PL269180A1 (en) 1988-08-18
CH677925A5 (en) 1991-07-15
PH24666A (en) 1990-09-07
GB2199579A (en) 1988-07-13
FR2607810A1 (en) 1988-06-10
ZA879093B (en) 1989-07-26
HUT45506A (en) 1988-07-28
IL84665A (en) 1991-11-21
ATA316887A (en) 1992-06-15
FR2607810B1 (en) 1989-12-01
FI875300A7 (en) 1988-06-04
GB8727978D0 (en) 1988-01-06
GR871897B (en) 1988-04-04
DK631287A (en) 1988-06-04
MY103004A (en) 1993-03-31
IT8748656A0 (en) 1987-12-01
GB2199579B (en) 1990-07-18
PT86255B (en) 1990-11-07
PL151588B1 (en) 1990-09-28
FI875300L (en) 1988-06-04
ES2010235A6 (en) 1989-11-01
JPS63145270A (en) 1988-06-17
IL84665A0 (en) 1988-05-31
LU87063A1 (en) 1988-07-14
AT395587B (en) 1993-01-25
HU198694B (en) 1989-11-28
FI875300A0 (en) 1987-12-01
AU8196287A (en) 1988-06-16
SE8704792D0 (en) 1987-12-01
DK631287D0 (en) 1987-12-01
JPH0678318B2 (en) 1994-10-05
NL8702897A (en) 1988-07-01
AU605522B2 (en) 1991-01-17
KR880007481A (en) 1988-08-27

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