SE8702527D0 - METHYLENE DERIVATIVES OF ANDROST-4-EN-3,17-DIONES AND PROCEDURE FOR THEIR PREPARATION - Google Patents

METHYLENE DERIVATIVES OF ANDROST-4-EN-3,17-DIONES AND PROCEDURE FOR THEIR PREPARATION

Info

Publication number
SE8702527D0
SE8702527D0 SE8702527A SE8702527A SE8702527D0 SE 8702527 D0 SE8702527 D0 SE 8702527D0 SE 8702527 A SE8702527 A SE 8702527A SE 8702527 A SE8702527 A SE 8702527A SE 8702527 D0 SE8702527 D0 SE 8702527D0
Authority
SE
Sweden
Prior art keywords
diones
androst
procedure
preparation
methylene derivatives
Prior art date
Application number
SE8702527A
Other languages
Swedish (sv)
Other versions
SE8702527L (en
Inventor
F Buzzetti
Salle E Di
P Lombardi
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of SE8702527D0 publication Critical patent/SE8702527D0/en
Publication of SE8702527L publication Critical patent/SE8702527L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C07J53/005—3 membered carbocyclic rings in position 12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

The present invention relates to new 6- or 7-methylen-1,2 beta -cyclopropanoandrost-4-ene-3,17-diones of the following formula <IMAGE> wherein R is hydrogen or fluorine; one of R1 and R2 is =CH2 and the other is hydrogen or C1-C4-alkyl, and, when R2 is =CH2, at least one of R and R1 is other than hydrogen, which are useful in therapy, in particular as anti-cancer agents.
SE8702527A 1986-06-20 1987-06-17 METHYLENE DERIVATIVES OF ANDROST-4-EN-3,17-DIONES AND PROCEDURE FOR THEIR PREPARATION SE8702527L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868615093A GB8615093D0 (en) 1986-06-20 1986-06-20 Methylene derivatives of androst-4-ene-1317-diones

Publications (2)

Publication Number Publication Date
SE8702527D0 true SE8702527D0 (en) 1987-06-17
SE8702527L SE8702527L (en) 1987-12-21

Family

ID=10599810

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8702527A SE8702527L (en) 1986-06-20 1987-06-17 METHYLENE DERIVATIVES OF ANDROST-4-EN-3,17-DIONES AND PROCEDURE FOR THEIR PREPARATION

Country Status (17)

Country Link
JP (1) JPS635097A (en)
AU (1) AU7429187A (en)
BE (1) BE1000648A4 (en)
DE (1) DE3719913A1 (en)
DK (1) DK315487A (en)
FI (1) FI872660A (en)
FR (1) FR2600254A1 (en)
GB (2) GB8615093D0 (en)
GR (1) GR870942B (en)
HU (1) HUT44037A (en)
IL (1) IL82895A0 (en)
IT (1) IT1204740B (en)
LU (1) LU86921A1 (en)
NL (1) NL8701430A (en)
PT (1) PT85122A (en)
SE (1) SE8702527L (en)
ZA (1) ZA874403B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8615092D0 (en) * 1986-06-20 1986-07-23 Erba Farmitalia Androst-4-ene-317-diones
CA1324619C (en) * 1988-07-26 1993-11-23 Kabushiki Kaisha Iseki Kaihatsu Koki Shield tunneling machine with eccentricity accommodating seal structure
CH683151A5 (en) * 1991-04-24 1994-01-31 Ciba Geigy Ag Contraception in female primates without affecting the menstrual cycle.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5614675B2 (en) * 1973-06-16 1981-04-06
DE3422187A1 (en) * 1984-06-12 1985-12-12 Schering AG, 1000 Berlin und 4709 Bergkamen 1,2SS-METHYLENE-4-ANDROSTEN AND 4,6-ANDROSTADIEN-3,17-DIONE

Also Published As

Publication number Publication date
GB2191777A (en) 1987-12-23
DE3719913A1 (en) 1987-12-23
IT1204740B (en) 1989-03-10
AU7429187A (en) 1987-12-24
SE8702527L (en) 1987-12-21
GB8615093D0 (en) 1986-07-23
PT85122A (en) 1987-07-01
NL8701430A (en) 1988-01-18
FI872660A (en) 1987-12-21
FR2600254A1 (en) 1987-12-24
BE1000648A4 (en) 1989-02-28
LU86921A1 (en) 1989-03-08
FI872660A0 (en) 1987-06-16
ZA874403B (en) 1987-12-21
GR870942B (en) 1987-10-19
IL82895A0 (en) 1987-12-20
HUT44037A (en) 1988-01-28
DK315487D0 (en) 1987-06-19
IT8720945A0 (en) 1987-06-18
GB8714416D0 (en) 1987-07-22
DK315487A (en) 1987-12-21
JPS635097A (en) 1988-01-11

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