SE8700527D0 - BENZOHETEROCYCLIC COMPOUNDS - Google Patents
BENZOHETEROCYCLIC COMPOUNDSInfo
- Publication number
- SE8700527D0 SE8700527D0 SE8700527A SE8700527A SE8700527D0 SE 8700527 D0 SE8700527 D0 SE 8700527D0 SE 8700527 A SE8700527 A SE 8700527A SE 8700527 A SE8700527 A SE 8700527A SE 8700527 D0 SE8700527 D0 SE 8700527D0
- Authority
- SE
- Sweden
- Prior art keywords
- substd
- thiomorpholino
- halogen
- opt
- methyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Abstract
(+8.5.86, 22.5.86, 23.7.86, 19.8.86, 30.9.86, 15.10.86, 18.12.86-JP-105655, 118568, 173370, 193838, 233837, 246050, 303515) (1703KM) - 4-Oxoquinoline-3-carboxylic acid cpds. of formula (I) and their salts are new. R1 is cyclopropyl opt. substd. by 1-3 substits. selected from lower alkyl and halogen; R2 is 5-9 membered opt. unsatd. heterocyclic ring which may be substd. R3 is lower alkyl which may be substd. by 1-3 substits. selected from a 5- or 6-membered satd. heterocyclic ring, lower alkylthio, amino, lower-alkylamino, lower alkanoyloxy, OH, lower alkoxy and halogen; and X is halogen. - Pref. R2 is opt. substd. 1-piperidinyl, 1-pyrrolidinyl, 1-homopiperazinyl, thiomorpholino, 1,4-diazabicyclo (4.3.0) nona-4-yl, thiomorpholino-4-oxide, thiomorpholino-4,4-dioxide, 1-hexahydropyridazinyl, 2-thiazolidinyl, 1-imidazolidinyl or 3,7-diazabicyclo (4.3.0) nona-3-yl. - 10 Cpds. of (I) including 7-(4-(5-methyl) 2-oxo-1,3-dioxolen -4-yl) methyl-1-piperazinyl) -1-cyclopropyl-6-fluoro- 8-methyl-1,4-dihydro-4-oxoquinoline -3-carboxylic acid are described.
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4092186 | 1986-02-25 | ||
JP10565586 | 1986-05-08 | ||
JP11856886 | 1986-05-22 | ||
JP17337086 | 1986-07-23 | ||
JP19383886 | 1986-08-19 | ||
JP23383786 | 1986-09-30 | ||
JP24605086 | 1986-10-15 | ||
JP30351586 | 1986-12-18 |
Publications (3)
Publication Number | Publication Date |
---|---|
SE8700527D0 true SE8700527D0 (en) | 1987-02-11 |
SE8700527L SE8700527L (en) | 1987-08-26 |
SE501371C2 SE501371C2 (en) | 1995-01-23 |
Family
ID=27572272
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8700527A SE501371C2 (en) | 1986-02-25 | 1987-02-11 | New 4-oxo:quinoline-3-carboxylic acid cpds. - having antimicrobial activity against Gram positive and Gram negative bacteria and other microorganisms |
Country Status (2)
Country | Link |
---|---|
KR (1) | KR970000950B1 (en) |
SE (1) | SE501371C2 (en) |
-
1987
- 1987-02-11 SE SE8700527A patent/SE501371C2/en unknown
- 1987-02-25 KR KR1019870001600A patent/KR970000950B1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
SE501371C2 (en) | 1995-01-23 |
KR870007912A (en) | 1987-09-22 |
KR970000950B1 (en) | 1997-01-21 |
SE8700527L (en) | 1987-08-26 |
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