SE8505716D0 - Novel compounds and conjugates thereof - Google Patents

Novel compounds and conjugates thereof

Info

Publication number
SE8505716D0
SE8505716D0 SE8505716A SE8505716A SE8505716D0 SE 8505716 D0 SE8505716 D0 SE 8505716D0 SE 8505716 A SE8505716 A SE 8505716A SE 8505716 A SE8505716 A SE 8505716A SE 8505716 D0 SE8505716 D0 SE 8505716D0
Authority
SE
Sweden
Prior art keywords
pct
iii
formula
conjugates
date jun
Prior art date
Application number
SE8505716A
Other languages
English (en)
Swedish (sv)
Original Assignee
Biocarb Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocarb Ab filed Critical Biocarb Ab
Priority to SE8505716A priority Critical patent/SE8505716D0/xx
Publication of SE8505716D0 publication Critical patent/SE8505716D0/xx
Priority to DE8686907006T priority patent/DE3673430D1/de
Priority to AT86907006T priority patent/ATE55380T1/de
Priority to JP61506365A priority patent/JPH0788375B2/ja
Priority to EP86907006A priority patent/EP0277139B1/en
Priority to PCT/SE1986/000550 priority patent/WO1987003589A1/en
Priority to DK395187A priority patent/DK395187D0/da
Priority to US90/002271A priority patent/US4956480B1/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
    • C12Q2337/20—Coumarin derivatives
    • C12Q2337/22—7-Amino-4-methylcoumarin, i.e. AMC, MCA

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Luminescent Compositions (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
SE8505716A 1985-12-03 1985-12-03 Novel compounds and conjugates thereof SE8505716D0 (sv)

Priority Applications (8)

Application Number Priority Date Filing Date Title
SE8505716A SE8505716D0 (sv) 1985-12-03 1985-12-03 Novel compounds and conjugates thereof
DE8686907006T DE3673430D1 (de) 1985-12-03 1986-12-02 7-amino-4-methyl-coumarin-3-carboxyalkyl-abkoemmlinge und fluoreszierende konjugate daraus.
AT86907006T ATE55380T1 (de) 1985-12-03 1986-12-02 7-amino-4-methyl-coumarin-3-carboxyalkylabk¯mmlinge und fluoreszierende konjugate daraus.
JP61506365A JPH0788375B2 (ja) 1985-12-03 1986-12-02 新規化合物およびそのコンジュゲ−ト
EP86907006A EP0277139B1 (en) 1985-12-03 1986-12-02 7-amino-4-methyl-coumarin-3-carboxyalkyl derivatives and fluorescent conjugates thereof
PCT/SE1986/000550 WO1987003589A1 (en) 1985-12-03 1986-12-02 7-amino-4-methyl-coumarin-3-caboxyalkyl derivates and fluorescent conjugates thereof
DK395187A DK395187D0 (da) 1985-12-03 1987-07-29 Hidtil ukendte coumarin-derivater og fluorescerende konjugater af saadanne derivater
US90/002271A US4956480B1 (en) 1985-12-03 1988-06-17 7-amino-4-methyl-coumarin-carboxyalkyl derivatives and fluorescent conjugates thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8505716A SE8505716D0 (sv) 1985-12-03 1985-12-03 Novel compounds and conjugates thereof

Publications (1)

Publication Number Publication Date
SE8505716D0 true SE8505716D0 (sv) 1985-12-03

Family

ID=20362325

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8505716A SE8505716D0 (sv) 1985-12-03 1985-12-03 Novel compounds and conjugates thereof

Country Status (6)

Country Link
US (1) US4956480B1 (xx)
EP (1) EP0277139B1 (xx)
JP (1) JPH0788375B2 (xx)
DE (1) DE3673430D1 (xx)
SE (1) SE8505716D0 (xx)
WO (1) WO1987003589A1 (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5112946A (en) * 1989-07-06 1992-05-12 Repligen Corporation Modified pf4 compositions and methods of use
US5248784A (en) * 1989-12-28 1993-09-28 Mitsui Toatsu Chemicals, Inc. 4-carbonyl-substituted coumarin compound
CA2032602C (en) * 1989-12-28 2001-12-25 Tsukasa Ohyama 4-carbonyl-substituted coumarin compound
US5648270A (en) * 1995-02-06 1997-07-15 Molecular Probes, Inc. Methods of sensing with fluorescent conjugates of metal-chelating nitrogen heterocycles
US5696157A (en) * 1996-11-15 1997-12-09 Molecular Probes, Inc. Sulfonated derivatives of 7-aminocoumarin
GB9716476D0 (en) 1997-08-04 1997-10-08 Amersham Int Plc Dye intermediate and method
EP1273584B1 (de) * 2001-07-03 2004-02-18 Dyomics GmbH Verbindungen auf der Basis von 2-bzw. 4-Chromenyliden-Merocyaninen und ihre Verwendung
US7150967B2 (en) 2002-04-08 2006-12-19 University Of Medicine & Dentistry Of New Jersey Fluorescent tags for amino acid and nucleic acid analysis
US8431416B2 (en) 2009-04-01 2013-04-30 Becton, Dickinson And Company Reactive heterocycle-substituted 7-hydroxycoumarins and their conjugates
US8318953B2 (en) 2010-06-23 2012-11-27 Aat Bioquest, Inc. Reactive coumarin derivatives and their use in cellular analyses
CN108707129A (zh) 2012-07-27 2018-10-26 太阳化学公司 作为油墨中的光引发剂和光敏剂的香豆素酮
PT3553054T (pt) * 2018-04-13 2023-04-18 Univ Evora Novos compostos fluorescentes e métodos de síntese dos mesmos
EP3747957A1 (en) 2019-06-07 2020-12-09 Universidade de Évora Fluorescent vinyl tiophene and bitiophene coumarins dyes and method of synthesis thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA522581A (en) * 1956-03-13 S. Long Robert Carboxymethyl derivatives of coumarin
US3008969A (en) * 1958-05-21 1961-11-14 American Cyanamid Co 4-substituted-7-carboalkoxyamino-coumarins

Also Published As

Publication number Publication date
JPH0788375B2 (ja) 1995-09-27
JPS63502178A (ja) 1988-08-25
US4956480A (en) 1990-09-11
DE3673430D1 (de) 1990-09-13
EP0277139A1 (en) 1988-08-10
EP0277139B1 (en) 1990-08-08
WO1987003589A1 (en) 1987-06-18
US4956480B1 (en) 1993-11-16

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