DE3673430D1 - 7-amino-4-methyl-coumarin-3-carboxyalkyl-abkoemmlinge und fluoreszierende konjugate daraus. - Google Patents

7-amino-4-methyl-coumarin-3-carboxyalkyl-abkoemmlinge und fluoreszierende konjugate daraus.

Info

Publication number
DE3673430D1
DE3673430D1 DE8686907006T DE3673430T DE3673430D1 DE 3673430 D1 DE3673430 D1 DE 3673430D1 DE 8686907006 T DE8686907006 T DE 8686907006T DE 3673430 T DE3673430 T DE 3673430T DE 3673430 D1 DE3673430 D1 DE 3673430D1
Authority
DE
Germany
Prior art keywords
combaters
carboxyalkyl
coumarin
amino
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8686907006T
Other languages
English (en)
Inventor
Don Robinson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biocarb AB
Original Assignee
Biocarb AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocarb AB filed Critical Biocarb AB
Application granted granted Critical
Publication of DE3673430D1 publication Critical patent/DE3673430D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
    • C12Q2337/20—Coumarin derivatives
    • C12Q2337/22—7-Amino-4-methylcoumarin, i.e. AMC, MCA

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Luminescent Compositions (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DE8686907006T 1985-12-03 1986-12-02 7-amino-4-methyl-coumarin-3-carboxyalkyl-abkoemmlinge und fluoreszierende konjugate daraus. Expired - Lifetime DE3673430D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8505716A SE8505716D0 (sv) 1985-12-03 1985-12-03 Novel compounds and conjugates thereof
PCT/SE1986/000550 WO1987003589A1 (en) 1985-12-03 1986-12-02 7-amino-4-methyl-coumarin-3-caboxyalkyl derivates and fluorescent conjugates thereof

Publications (1)

Publication Number Publication Date
DE3673430D1 true DE3673430D1 (de) 1990-09-13

Family

ID=20362325

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686907006T Expired - Lifetime DE3673430D1 (de) 1985-12-03 1986-12-02 7-amino-4-methyl-coumarin-3-carboxyalkyl-abkoemmlinge und fluoreszierende konjugate daraus.

Country Status (6)

Country Link
US (1) US4956480B1 (de)
EP (1) EP0277139B1 (de)
JP (1) JPH0788375B2 (de)
DE (1) DE3673430D1 (de)
SE (1) SE8505716D0 (de)
WO (1) WO1987003589A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5112946A (en) * 1989-07-06 1992-05-12 Repligen Corporation Modified pf4 compositions and methods of use
US5248784A (en) * 1989-12-28 1993-09-28 Mitsui Toatsu Chemicals, Inc. 4-carbonyl-substituted coumarin compound
CA2032602C (en) * 1989-12-28 2001-12-25 Tsukasa Ohyama 4-carbonyl-substituted coumarin compound
US5648270A (en) * 1995-02-06 1997-07-15 Molecular Probes, Inc. Methods of sensing with fluorescent conjugates of metal-chelating nitrogen heterocycles
US5696157A (en) * 1996-11-15 1997-12-09 Molecular Probes, Inc. Sulfonated derivatives of 7-aminocoumarin
GB9716476D0 (en) 1997-08-04 1997-10-08 Amersham Int Plc Dye intermediate and method
EP1273584B1 (de) * 2001-07-03 2004-02-18 Dyomics GmbH Verbindungen auf der Basis von 2-bzw. 4-Chromenyliden-Merocyaninen und ihre Verwendung
US7150967B2 (en) 2002-04-08 2006-12-19 University Of Medicine & Dentistry Of New Jersey Fluorescent tags for amino acid and nucleic acid analysis
US8431416B2 (en) 2009-04-01 2013-04-30 Becton, Dickinson And Company Reactive heterocycle-substituted 7-hydroxycoumarins and their conjugates
US8318953B2 (en) 2010-06-23 2012-11-27 Aat Bioquest, Inc. Reactive coumarin derivatives and their use in cellular analyses
CN108707129A (zh) 2012-07-27 2018-10-26 太阳化学公司 作为油墨中的光引发剂和光敏剂的香豆素酮
PT3553054T (pt) * 2018-04-13 2023-04-18 Univ Evora Novos compostos fluorescentes e métodos de síntese dos mesmos
EP3747957A1 (de) 2019-06-07 2020-12-09 Universidade de Évora Leuchtsfarbstoffe von vinyl-tiophen und -bitiophen-coumarin- und verfahren zu ihrer synthese

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA522581A (en) * 1956-03-13 S. Long Robert Carboxymethyl derivatives of coumarin
US3008969A (en) * 1958-05-21 1961-11-14 American Cyanamid Co 4-substituted-7-carboalkoxyamino-coumarins

Also Published As

Publication number Publication date
JPH0788375B2 (ja) 1995-09-27
JPS63502178A (ja) 1988-08-25
US4956480A (en) 1990-09-11
EP0277139A1 (de) 1988-08-10
SE8505716D0 (sv) 1985-12-03
EP0277139B1 (de) 1990-08-08
WO1987003589A1 (en) 1987-06-18
US4956480B1 (en) 1993-11-16

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Legal Events

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