SE8503763D0 - phenethanolamine derivatives - Google Patents

phenethanolamine derivatives

Info

Publication number
SE8503763D0
SE8503763D0 SE8503763A SE8503763A SE8503763D0 SE 8503763 D0 SE8503763 D0 SE 8503763D0 SE 8503763 A SE8503763 A SE 8503763A SE 8503763 A SE8503763 A SE 8503763A SE 8503763 D0 SE8503763 D0 SE 8503763D0
Authority
SE
Sweden
Prior art keywords
compounds
image
general formula
hydrogen atom
group
Prior art date
Application number
SE8503763A
Other languages
Swedish (sv)
Other versions
SE8503763L (en
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of SE8503763D0 publication Critical patent/SE8503763D0/en
Publication of SE8503763L publication Critical patent/SE8503763L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D263/06—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Compounds of the general formula (I> <IMAGE> (wherein R represents a hydrogen atom or a straight chain C1-3 alkyl group and n is 1 or 2, and physiologically acceptable acid addition salts, solvates and metabolically labile esters thereof) of use in the treatment of heart failure, cardiogenic shock or ischaemic heart disease. Also disclosed are compounds of general formula (XV> <IMAGE> (wherein n is 1 or 2, R<2>, R<3>, R<4> and R<5> each represent a hydrogen atom or a protecting group and R<8> represents a carboxyl group, or a salt or C1-5 alkyl ester thereof) which are of value as intermediates.
SE8503763A 1984-08-09 1985-08-09 phenethanolamine derivatives SE8503763L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848420303A GB8420303D0 (en) 1984-08-09 1984-08-09 Chemical compounds

Publications (2)

Publication Number Publication Date
SE8503763D0 true SE8503763D0 (en) 1985-08-09
SE8503763L SE8503763L (en) 1986-02-10

Family

ID=10565130

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8503763A SE8503763L (en) 1984-08-09 1985-08-09 phenethanolamine derivatives

Country Status (24)

Country Link
JP (1) JPS6183154A (en)
KR (1) KR860001783A (en)
AU (1) AU4590885A (en)
BE (1) BE903041A (en)
CH (1) CH667870A5 (en)
DE (1) DE3528700A1 (en)
DK (1) DK364185A (en)
ES (5) ES8703829A1 (en)
FI (1) FI853057L (en)
FR (1) FR2568874B1 (en)
GB (2) GB8420303D0 (en)
GR (1) GR851949B (en)
HU (1) HU196171B (en)
IL (1) IL76062A (en)
IT (1) IT1184685B (en)
LU (1) LU86038A1 (en)
MY (1) MY102187A (en)
NL (1) NL8502212A (en)
NO (1) NO853151L (en)
NZ (1) NZ213055A (en)
PH (1) PH21664A (en)
PT (1) PT80936B (en)
SE (1) SE8503763L (en)
ZA (1) ZA856021B (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1165845A (en) * 1955-05-28 1958-10-29 Philips Nv Secondary amines bearing substituents and their preparation
DE3061205D1 (en) * 1979-06-16 1983-01-05 Beecham Group Plc Secondary amines, their preparation and use in pharmaceutical compositions

Also Published As

Publication number Publication date
MY102187A (en) 1992-04-30
FI853057L (en) 1986-02-10
ES8801783A1 (en) 1988-02-16
CH667870A5 (en) 1988-11-15
ES552097A0 (en) 1988-02-16
HUT39149A (en) 1986-08-28
GB2162845B (en) 1988-06-08
NO853151L (en) 1986-02-10
FR2568874B1 (en) 1988-09-09
GB8520111D0 (en) 1985-09-18
PH21664A (en) 1988-01-13
IT1184685B (en) 1987-10-28
IL76062A (en) 1989-07-31
JPS6183154A (en) 1986-04-26
ZA856021B (en) 1986-05-28
DK364185D0 (en) 1985-08-09
GB8420303D0 (en) 1984-09-12
KR860001783A (en) 1986-03-22
ES557416A0 (en) 1988-02-16
ES8802487A1 (en) 1988-07-01
HU196171B (en) 1988-10-28
ES8703829A1 (en) 1987-03-01
NL8502212A (en) 1986-03-03
GB2162845A (en) 1986-02-12
AU4590885A (en) 1986-02-13
ES546010A0 (en) 1987-03-01
ES557415A0 (en) 1988-07-01
ES8801784A1 (en) 1988-02-16
ES8802488A1 (en) 1988-07-01
PT80936B (en) 1987-06-02
IL76062A0 (en) 1985-12-31
NZ213055A (en) 1988-11-29
ES557414A0 (en) 1988-07-01
FR2568874A1 (en) 1986-02-14
PT80936A (en) 1985-09-01
SE8503763L (en) 1986-02-10
GR851949B (en) 1985-12-11
BE903041A (en) 1986-02-10
LU86038A1 (en) 1986-09-11
FI853057A0 (en) 1985-08-09
DE3528700A1 (en) 1986-03-06
IT8548467A0 (en) 1985-08-09
DK364185A (en) 1986-02-10

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Legal Events

Date Code Title Description
NAV Patent application has lapsed

Ref document number: 8503763-8

Effective date: 19900301