ES8801784A1 - Phenethanolamine derivatives - Google Patents
Phenethanolamine derivativesInfo
- Publication number
- ES8801784A1 ES8801784A1 ES557416A ES557416A ES8801784A1 ES 8801784 A1 ES8801784 A1 ES 8801784A1 ES 557416 A ES557416 A ES 557416A ES 557416 A ES557416 A ES 557416A ES 8801784 A1 ES8801784 A1 ES 8801784A1
- Authority
- ES
- Spain
- Prior art keywords
- compounds
- image
- general formula
- hydrogen atom
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D263/06—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Compounds of the general formula (I> < IMAGE > (wherein R represents a hydrogen atom or a straight chain C1-3 alkyl group and n is 1 or 2, and physiologically acceptable acid addition salts, solvates and metabolically labile esters thereof) of use in the treatment of heart failure, cardiogenic shock or ischaemic heart disease. Also disclosed are compounds of general formula (XV> < IMAGE > (wherein n is 1 or 2, R<2>, R<3>, R<4> and R<5> each represent a hydrogen atom or a protecting group and R<8> represents a carboxyl group, or a salt or C1-5 alkyl ester thereof) which are of value as intermediates.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB848420303A GB8420303D0 (en) | 1984-08-09 | 1984-08-09 | Chemical compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8801784A1 true ES8801784A1 (en) | 1988-02-16 |
ES557416A0 ES557416A0 (en) | 1988-02-16 |
Family
ID=10565130
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES546010A Expired ES8703829A1 (en) | 1984-08-09 | 1985-08-08 | Phenethanolamine derivatives |
ES552097A Expired ES8801783A1 (en) | 1984-08-09 | 1986-02-17 | Phenethanolamine derivatives |
ES557415A Expired ES8802488A1 (en) | 1984-08-09 | 1987-02-16 | Phenethanolamine derivatives |
ES557414A Expired ES8802487A1 (en) | 1984-08-09 | 1987-02-16 | Phenethanolamine derivatives |
ES557416A Expired ES8801784A1 (en) | 1984-08-09 | 1987-02-16 | Phenethanolamine derivatives |
Family Applications Before (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES546010A Expired ES8703829A1 (en) | 1984-08-09 | 1985-08-08 | Phenethanolamine derivatives |
ES552097A Expired ES8801783A1 (en) | 1984-08-09 | 1986-02-17 | Phenethanolamine derivatives |
ES557415A Expired ES8802488A1 (en) | 1984-08-09 | 1987-02-16 | Phenethanolamine derivatives |
ES557414A Expired ES8802487A1 (en) | 1984-08-09 | 1987-02-16 | Phenethanolamine derivatives |
Country Status (24)
Country | Link |
---|---|
JP (1) | JPS6183154A (en) |
KR (1) | KR860001783A (en) |
AU (1) | AU4590885A (en) |
BE (1) | BE903041A (en) |
CH (1) | CH667870A5 (en) |
DE (1) | DE3528700A1 (en) |
DK (1) | DK364185A (en) |
ES (5) | ES8703829A1 (en) |
FI (1) | FI853057L (en) |
FR (1) | FR2568874B1 (en) |
GB (2) | GB8420303D0 (en) |
GR (1) | GR851949B (en) |
HU (1) | HU196171B (en) |
IL (1) | IL76062A (en) |
IT (1) | IT1184685B (en) |
LU (1) | LU86038A1 (en) |
MY (1) | MY102187A (en) |
NL (1) | NL8502212A (en) |
NO (1) | NO853151L (en) |
NZ (1) | NZ213055A (en) |
PH (1) | PH21664A (en) |
PT (1) | PT80936B (en) |
SE (1) | SE8503763L (en) |
ZA (1) | ZA856021B (en) |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1165845A (en) * | 1955-05-28 | 1958-10-29 | Philips Nv | Secondary amines bearing substituents and their preparation |
EP0021636B1 (en) * | 1979-06-16 | 1982-12-01 | Beecham Group Plc | Secondary amines, their preparation and use in pharmaceutical compositions |
-
1984
- 1984-08-09 GB GB848420303A patent/GB8420303D0/en active Pending
-
1985
- 1985-08-08 GR GR851949A patent/GR851949B/el unknown
- 1985-08-08 AU AU45908/85A patent/AU4590885A/en not_active Abandoned
- 1985-08-08 ES ES546010A patent/ES8703829A1/en not_active Expired
- 1985-08-09 CH CH3433/85A patent/CH667870A5/en not_active IP Right Cessation
- 1985-08-09 SE SE8503763A patent/SE8503763L/en not_active Application Discontinuation
- 1985-08-09 KR KR1019850005741A patent/KR860001783A/en not_active Application Discontinuation
- 1985-08-09 LU LU86038A patent/LU86038A1/en unknown
- 1985-08-09 IT IT48467/85A patent/IT1184685B/en active
- 1985-08-09 NZ NZ213055A patent/NZ213055A/en unknown
- 1985-08-09 NL NL8502212A patent/NL8502212A/en not_active Application Discontinuation
- 1985-08-09 HU HU853082A patent/HU196171B/en unknown
- 1985-08-09 DE DE19853528700 patent/DE3528700A1/en not_active Withdrawn
- 1985-08-09 IL IL76062A patent/IL76062A/en unknown
- 1985-08-09 PT PT80936A patent/PT80936B/en unknown
- 1985-08-09 JP JP60174406A patent/JPS6183154A/en active Pending
- 1985-08-09 NO NO853151A patent/NO853151L/en unknown
- 1985-08-09 DK DK364185A patent/DK364185A/en not_active Application Discontinuation
- 1985-08-09 ZA ZA856021A patent/ZA856021B/en unknown
- 1985-08-09 PH PH32623A patent/PH21664A/en unknown
- 1985-08-09 BE BE0/215451A patent/BE903041A/en not_active IP Right Cessation
- 1985-08-09 FR FR8512245A patent/FR2568874B1/en not_active Expired
- 1985-08-09 FI FI853057A patent/FI853057L/en not_active Application Discontinuation
- 1985-08-09 GB GB08520111A patent/GB2162845B/en not_active Expired
-
1986
- 1986-02-17 ES ES552097A patent/ES8801783A1/en not_active Expired
-
1987
- 1987-02-16 ES ES557415A patent/ES8802488A1/en not_active Expired
- 1987-02-16 ES ES557414A patent/ES8802487A1/en not_active Expired
- 1987-02-16 ES ES557416A patent/ES8801784A1/en not_active Expired
- 1987-10-01 MY MYPI87002763A patent/MY102187A/en unknown
Also Published As
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